Alnylam Pharmaceuticals Inc - Company Profile

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Alnylam Pharmaceuticals Inc: Overview

Alnylam Pharmaceuticals Inc (Alnylam) is a biopharmaceutical company, which discovers, develops, and commercializes drugs based on RNAi interference. The company’s marketed RNAi therapies include Onpattro, which is used in the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR amyloidosis; Givlaari for acute hepatic porphyria, Amvuttra, for the treatment of ATTR amyloidosis with cardiomyopathy; and Oxlumo for primary hyperoxaluria type 1 (PH1). The company develops a broad pipeline of investigational RNAi drugs in the areas of genetic medicines, hepatic infectious, cardio-metabolic, and central nervous system (CNS) diseases. Its late-stage product candidates include vutrisiran for ATTR amyloidosis, inclisiran for hypercholesterolemia, fitusiran for hemophilia and rare bleeding disorders, and lumasiran for severe PH1. The company operates subsidiaries in North America, Europe and Asia-Pacific. Alnylam is headquartered in Cambridge, Massachusetts, the US.

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Headquarters United States of America

Address 675 W Kendall St, Cambridge, Massachusetts, 02142-1168


Telephone 1 617 5518200

No of Employees 2,100

Industry Pharmaceuticals and Healthcare

Ticker Symbol & Exchange ALNY (NASD)

Revenue (2022) $1.8B 76.2% (2022 vs 2021)

EPS XYZ

Net Income (2022) XYZ 61.1% (2022 vs 2021)

Market Cap* $18.7B

Net Profit Margin (2022) XYZ 77.9% (2022 vs 2021)

* As of and is in US$
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Alnylam Pharmaceuticals Inc premium industry data and analytics

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Catalyst Calendar

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Lead Sheet

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Pipeline Drugs

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Clinical Trials

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Insights

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Regulatory Milestones

Track drug and patent expiries along with geographies impacted.

5

Sales & Consensus Forecasts

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Marketed Drugs

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Products and Services

Products Brands
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Marketed: Onpattro
Onpattro - RNAi therapeutic for treatment of hATTR amyloidosis Givlaari
XYZ XYZ
XYZ XYZ
XYZ XYZ
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History

History section provides information on new products, mergers, acquisitions, expansions, approvals, and many more key events.

Year Event Description
2023 Others In September, the company announced the first-ever recommendations for patient- and family-centred holistic care for people living with hereditary transthyretin-mediated amyloidosis, also called hATTR or ATTRv.
2023 Contracts/Agreements In July, the company entered into a strategic agreement with Roche to develop and commercialize zilebesiran, Alnylam’s investigational RNAi therapeutic for the treatment of hypertension.
2023 Contracts/Agreements In March, the company and Medison Pharma announced an expansion of their existing partnership to a multi-regional agreement that includes Poland, Czech Republic, Hungary, Slovakia, Lithuania, Estonia and Latvia, in addition to Israel.
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Competitor Comparison

Key Parameters Alnylam Pharmaceuticals Inc F. Hoffmann-La Roche Ltd AstraZeneca Plc GSK plc Eli Lilly and Co
Headquarters United States of America Switzerland United Kingdom United Kingdom United States of America
City Cambridge Basel Cambridge Brentford Indianapolis
State/Province Massachusetts - England England Indiana
No. of Employees 2,100 103,605 89,900 70,212 43,000
Entity Type Public Public Public Public Public
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Executives
Name Position Board Since Age
Amy W. Schulman Chairman Executive Board 2023 -
Yvonne Greenstreet, MBChB Director; Chief Executive Officer Executive Board 2022 -
Jeff Poulton Executive Vice President; Chief Financial Officer Senior Management 2019 55
Indrani Franchini Secretary; Executive Vice President; Chief Legal Officer Senior Management 2022 51
Pushkal P. Garg, M.D. Executive Vice President - Development & Medical Affairs; Chief Medical Officer Senior Management 2022 55
Non Dignissim Eros Proin vel Convallis 2024 XY
Non Dignissim Eros Proin vel Convallis 2024 XY
Non Dignissim Eros Proin vel Convallis 2024 XY
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