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Denali Therapeutics Inc: Overview

Denali Therapeutics Inc (Denali Therapeutics) is a clinical-stage biopharmaceutical company that focuses on the development of therapeutics for the treatment of neurodegenerative diseases. Its proprietary drug delivery platform technologies include an antibody transport vehicle and an enzyme transport vehicle designed to deliver large molecules across the blood-brain barrier (BBB). Its pipeline products are intended for the treatment of Alzheimer’s disease, dementia with Lewy bodies, Parkinson’s disease, multiple system atrophy, lysosomal storage disorder MPS II, neurodegeneration, amyotrophic lateral sclerosis and other indications. The company’s product pipeline include DNL201, DNL151, ATV:aSyn, for Parkinson’s disease, DNL747, ATV:Tau, ATV:TREM2, for Alzheimer’s disease; and CH1 and LF1, for neurodegeneration. It has development and commercialization rights to all of its programs, including the programs partnered with Takeda. The company operates in the UK and the US. Denali Therapeutics is headquartered in San Francisco, California, the US.

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Headquarters United States of America

Address 161 Oyster Point Blvd, South San Francisco, California, 94080-1910


Telephone 1 650 8668548

No of Employees 445

Industry Pharmaceuticals and Healthcare

Ticker Symbol & Exchange DNLI (NASD)

Revenue (2022) $330.5M 204.7% (2022 vs 2021)

EPS XYZ

Net Income (2022) XYZ 55.5% (2022 vs 2021)

Market Cap* $2.5B

Net Profit Margin (2022) XYZ 85.4% (2022 vs 2021)

* As of and is in US$
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Denali Therapeutics Inc premium industry data and analytics

80+

Lead Sheet

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Catalyst Calendar

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Pipeline Drugs

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20+

Clinical Trials

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7

Regulatory Milestones

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Insights

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Products and Services

Products
Product Pipeline:
Lysosomal Function
LRRK2
XYZ
XYZ
XYZ
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Competitor Comparison

Key Parameters Denali Therapeutics Inc Eli Lilly and Co Biogen Inc Ionis Pharmaceuticals Inc Prothena Corp Plc
Headquarters United States of America United States of America United States of America United States of America Ireland
City South San Francisco Indianapolis Cambridge Carlsbad Dublin
State/Province California Indiana Massachusetts California -
No. of Employees 445 43,000 7,570 927 173
Entity Type Public Public Public Public Public
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Executives
Name Position Board Since Age
Vicki Sato Chairman Executive Board 2016 74
Ryan J. Watts President; Director; Chief Executive Officer Executive Board 2015 47
Cindy Dunkle Chief People Officer Senior Management - -
Carole Ho Head - Development; Chief Medical Officer Senior Management 2015 50
Joe Lewcock Chief Scientific Officer; Head - Discovery Senior Management - -
Non Dignissim Eros Proin vel Convallis 2024 XY
Non Dignissim Eros Proin vel Convallis 2024 XY
Non Dignissim Eros Proin vel Convallis 2024 XY
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