Leap Therapeutics Inc - Company Profile

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Leap Therapeutics Inc: Overview

Leap Therapeutics Inc (Leap Therapeutics) is a clinical-stage biopharmaceutical company that develops novel therapeutics to treat patients with different types of cancer. The company’s pipeline products include DKN-01. DKN-1 is a monoclonal antibody that targets the Dickkopf-1 (DKK-1) protein, intended for the treatment of gastroesophageal cancer, prostate cancer and gynecologic cancer. FL-301, a monoclonal antibody that targets Claudin18.2, is being tested in patients with gastric and pancreatic cancer. The company has an agreement with BeiGene Ltd for development rights and commercialization of DKN-01 in Australia, Asia (excluding Japan) and New Zealand. Leap Therapeutics is headquartered in Cambridge, Massachusetts, the US.

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Headquarters United States of America

Address 47 Thorndike St Ste B1-1, Cambridge, Massachusetts, 02141-1799


Telephone 1 617 2524343

No of Employees 54

Industry Pharmaceuticals and Healthcare

Ticker Symbol & Exchange LPTX (NASD)

EPS XYZ

Net Income (2022) XYZ -49.1% (2022 vs 2021)

Market Cap* $113.3M

Net Profit Margin (2020) XYZ -47.5% (2022 vs 2021)

   

* As of and is in US$
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Leap Therapeutics Inc premium industry data and analytics

30+

Lead Sheet

Understand when and why to target accounts of prospective leads, as well as who to reach out to, drawing on intelligence for Leap Therapeutics Inc’s relevant decision makers and contact details.

20+

Clinical Trials

Determine Leap Therapeutics Inc go-to-market proposition and gain insight into the company’s clinical operations, recruitment, and trial strategy.

20+

Catalyst Calendar

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8

Pipeline Drugs

Identify which of Leap Therapeutics Inc’s products will be commercialized, helping you to better contend with shifting product portfolios, and allowing you to stay one step ahead of the market.

3

Insights

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2

Regulatory Milestones

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Products and Services

Products
Pipeline
DKN-01 - Gastroesophageal Cancer/ Prostate Cancer / Gynecologic Cancer
FL-301 (NBL-105) - Gastric/ Pancreatic
XYZ
XYZ
XYZ
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History

History section provides information on new products, mergers, acquisitions, expansions, approvals, and many more key events.

Year Event Description
2023 Contracts/Agreements In March, the company entered into an agreement with BeiGene for trial, a randomized controlled trial of DKN-01 in combination with BeiGene's anti-PD-1 antibody, tislelizumab, and chemotherapy in first-line gastric cancer patients, as a clinical collaboration with BeiGene supplying tislelizumab.
2023 Contracts/Agreements In January, the company entered into an agreement to acquire Flame Biosciences, Inc.
2022 Contracts/Agreements In January, the company entered into an agreement with Leica Biosystems to develop companion diagnostic tests to detect Dickkopf-related protein 1 (DKK1) for cancer therapy.
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Competitor Comparison

Key Parameters Leap Therapeutics Inc Merck & Co Inc Pfizer Inc Bristol-Myers Squibb Co Amgen Inc
Headquarters United States of America United States of America United States of America United States of America United States of America
City Cambridge Kenilworth New York Princeton Thousand Oaks
State/Province Massachusetts New Jersey New York New Jersey California
No. of Employees 54 72,000 88,000 34,100 26,700
Entity Type Public Public Public Public Public
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Executives
Name Position Board Since Age
Christopher K. Mirabelli, Ph.D. Chairman Executive Board 2016 68
Douglas E. Onsi Director; Chief Executive Officer; President Executive Board 2020 54
Augustine Lawlor Chief Operating Officer Senior Management 2016 66
Cyndi Sirard, M.D. Chief Medical Officer Senior Management 2020 53
Jason Baum, Ph.D. Chief Scientific Officer Senior Management 2023 44
Non Dignissim Eros Proin vel Convallis 2024 XY
Non Dignissim Eros Proin vel Convallis 2024 XY
Non Dignissim Eros Proin vel Convallis 2024 XY
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