Mesoblast Ltd - Company Profile

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Mesoblast Ltd (Mesoblast) is a regenerative medicine company that develops regenerative cell-based products. Its most advanced candidate, remestemcel-L, is in Phase III clinical trials under the brand name RYONCIL for the treatment of pediatric steroid-refractory acute graft versus host disease (SR-aGVHD). Mesoblast is advancing rexlemestrocel for localized inflammatory diseases including advanced heart failure, and end-stage ischemic heart failure, and MPc-06-ID (rexlemestrocel) for the treatment of chronic low back pain. The company employs its proprietary technology platform to discover and treat cardiac diseases, and hematological diseases, mesenchymal lineage adult stem cells (MLCs), spine and musculoskeletal disorders and immune-mediated and inflammatory conditions. The company has operations in the US, Australia, and Singapore. Mesoblast is headquartered in Melbourne, Victoria, Australia.

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Headquarters Australia

Address L 38 55 Collins St, Melbourne, Victoria, 3000


Telephone 61 3 96396036

No of Employees 83

Industry Pharmaceuticals and Healthcare

Ticker Symbol & Exchange MSB (ASX)

Revenue (2022) $7.5M -26.6% (2022 vs 2021)

EPS XYZ

Net Income (2022) XYZ 10.4% (2022 vs 2021)

Market Cap* $550.5M

Net Profit Margin (2022) XYZ -22.1% (2022 vs 2021)

* As of and is in US$
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Mesoblast Ltd premium industry data and analytics

60+

Clinical Trials

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30+

Catalyst Calendar

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20+

Insights

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Lead Sheet

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18+

Pipeline Drugs

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7

Regulatory Milestones

Track drug and patent expiries along with geographies impacted.

1

Marketed Drugs

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Products and Services

Products Brands
Pipeline Ryoncil
Remestemcel-L: Revascor
Steroid-Refractory Acute Graft Versus Host Disease (Children)
XYZ
XYZ
XYZ
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History

History section provides information on new products, mergers, acquisitions, expansions, approvals, and many more key events.

Year Event Description
2024 Regulatory Approval In February, the company received approval from the US Food and Drug Administration for its allogeneic cell therapy Revascor (rexlemestrocel-L) from the randomized controlled trial in children with hypoplastic left heart syndrome.
2023 Contracts/Agreements In November, the company entered into an agreement with the Blood and Marrow Transplant Clinical Trials Network to develop a pivotal trial of Ryoncil (remestemcel-L) in the treatment of adults with steroid-refractory acute graft versus host disease.
2023 Regulatory Approval In February, the company secured an approval from the United States Food and Drug Administration’s (FDA) Office of Tissues and Advanced Therapies for Regenerative Medicine Advanced Therapy (RMAT) designation for rexlemestrocel-L in the treatment of chronic low back pain (CLBP) associated with disc degeneration in combination with hyaluronic acid (HA) as delivery agent for injection into the lumbar disc.
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Competitor Comparison

Key Parameters Mesoblast Ltd CSL Ltd Acrux Ltd Genetic Technologies Ltd IDT Australia Ltd
Headquarters Australia Australia Australia Australia Australia
City Melbourne Melbourne Melbourne Melbourne Melbourne
State/Province Victoria Victoria Victoria Victoria Victoria
No. of Employees 83 32,065 43 60 156
Entity Type Public Public Public Public Public
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Executives
Name Position Board Since Age
Silviu Itescu Managing Director; Director; Chief Executive Officer Executive Board 2011 -
Eric Rose, MD Chief Medical Officer; Director Executive Board 2022 -
Dagmar Rosa-Bjorkeson Chief Operating Officer Senior Management 2021 -
Andrew Chaponnel Chief Financial Officer - Interim Senior Management 2021 -
Joseph R. Swedish Chairman Non Executive Board 2019 -
Non Dignissim Eros Proin vel Convallis 2024 XY
Non Dignissim Eros Proin vel Convallis 2024 XY
Non Dignissim Eros Proin vel Convallis 2024 XY
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