GlobalData Plc

The ovarian cancer space across the seven major markets of the US, France, Germany, Italy, Spain, the UK, and Japan, is set to rise from around $1.2 billion in 2015 to over $5.2 billion by 2025, representing a strong compound annual growth rate of 15.5%, according to GlobalData, a recognized leader in providing business information and analytics.

The company’s latest report states that the key driver of this growth will be the establishment of new standard of care (SOC) maintenance therapies in the first and second lines of treatment for newly diagnosed and recurrent patients. The anticipated extended durations of therapy in the maintenance settings should fuel the sales of poly ADP-ribose polymerase (PARP) inhibitors and immune checkpoint modulators, as their efficacy data is expected to justify their expensive price tags.

Marc C. Hansel, Ph.D., Healthcare Analyst for GlobalData, explains: “PARP inhibitors are expected to be a major addition to the treatment paradigm for patients with deleterious germline or somatic BRCA mutations or BRCA-like phenotypes. AstraZeneca’s PARP inhibitor, Lynparza (olaparib), enjoyed two years alone on the ovarian cancer market without direct competition until Clovis Oncology’s Rubraca (rucaparib) joined the US market in December 2016.”

In the US, Lynparza is currently indicated for the fourth-line treatment of patients with a germline BRCA mutation. While Rubraca received a label for the third line in the same patient population, it also includes both germline and somatic BRCA. Although this was a success for Clovis, AstraZeneca is set to retake the lead after it announced top-line results from its Phase III SOLO2 study, which investigated Lynparza use in the second-line maintenance treatment setting.

Hansel continues: “While a plethora of PARP inhibitor drug choices may exist in the coming years, many unanswered questions still remain. For example, when in the treatment pathway PARP inhibitors should be used; whether they are best used as maintenance treatment after chemotherapy, as monotherapy for active therapy, or in combination with chemotherapy; what the molecular mechanism responsible for resistance are, and whether they can be overcome; and whether patients can be treated again with the same PARP inhibitor later in the treatment paradigm.

“GlobalData believes that drug companies may be able to differentiate themselves from the crowded field if they can provide answers to these questions. Answering them, along with showing robust efficacy and safety data, would go a long way to help companies stand above the competition and achieve commercial success.”

Information based on GlobalData’s report: OpportunityAnalyzer: Ovarian Cancer Opportunity Analysis and Forecasts to 2025

Related Intelligence

Want more Insight like this?

Our interactive subscription platform has the most comprehensive data and analysis in your industry.

Request a Demo

Related Consulting

How can we help your business?

Our consultants are skilled in every specialist market niche to deliver solutions specifically designed for your individual requirements.

Request a Callback

    Press Release Healthcare

    Late-stage CKD-induced comorbidity therapeutics market to reach $10.5bn by 2026

    Sales for chronic kidney disease (CKD)-induced hyperparathyroidism (HPT), hyperphosphatemia (HP), and hyperkalemia (HK) therapeutics were estimated to be $4.2bn across the seven major markets (7MM*) in 2016. This is expected to grow to $10.5bn in 2026, at a Compound Annual Growth Rate (CAGR) of 9.5%, according to GlobalData, a leading data and analytics company.

    Press Release Healthcare

    Majority of oncology clinical trials in China failed to meet enrolment targets

    The majority of oncology clinical trials in China that had a start date between 1 January 2012 and 31 December 2017 failed to meet the planned enrolment targets, according to GlobalData, a leading data and analytics company. The company identified and analyzed enrollment efficiencies of 324 clinical trials during the period and found that on...

    Press Release Healthcare

    Need for supportive care in oncology will increase during the next decade

    The need for effective supportive care in oncology will increase in the next decade as patients continue to live longer and cancer progresses to become more like a chronic disease. This includes the need for chemotherapy-related conditions, as chemotherapy will remain the backbone of cancer therapy for the foreseeable future, observes GlobalData, a leading data and analytics company.

    Press Release Healthcare

    World Cancer Day: What will 2018 mean for cancer research and treatment?

    The theme of this year’s World Cancer Day held on 4th February of “We can. I can.” aimed to reinforce the public message that all individuals and groups can play their part in reducing the global burden of cancer. Indeed in recent years many events have involved collaborations between traditional drug developers, cancer treatment professionals and those of varying disciplines. Examples include the IBM Watson supercomputer which is helping physicians make treatment decisions and the development of other databases such as ASCO’s CancerLinQ which assists oncologists in monitoring and analyzing patient data.

    Press Release Healthcare

    Melanoma sales are projected to rise to $5.5bn in 2026

    The value of the melanoma market was estimated to be $3.3bn across the seven major markets (7MM*) in 2016. This is expected to grow to $5.5bn in 2026, at a Compound Annual Growth Rate (CAGR) of 5.3%, according to GlobalData, a leading data and analytics company.

Media Enquiries

If you are a member of the press or media and require any further information, please get in touch, as we’re very happy to help.

Emailpr@globaldata.com
PhoneEMEA: +44 207 832 4399
PhoneAPAC: +91 40 6616 6809
Onlinecontact online

56% of #consumers are concerned about the impact of diet. Join us for more insight @incosmetics #cosmetics #trends… https://t.co/wJOJOqYIJF