GlobalData Plc
  • Press Release

    Significant advances in diabetes medicine have been made, but many unmet needs remain, says GlobalData

Advances in diabetes medicine, such as  anti-diabetic oral medications, incretin therapies, and novel insulin formulations have been made over the past century, but many  unmet needs remain for this complex and difficult-to-treat disease, says GlobalData, a leading data and analytics company.

World Diabetes Day (14th November) aims to improve awareness of hyperglycemia (the major hallmark of the disease) and its effects.

According to interviewed Key Opinion Leaders (KOLs), there are four pressing unmet needs in the diabetes space. These unmet needs apply broadly for both Type 1 Diabetes (T1D) and Type 2 Diabetes (T2D).

Dr. Jesus Cuaron, Managing Analyst at GlobalData, comments: “There is a need for additional treatments that provide both glycemic and non-glycemic benefits, especially since the control of diabetes comorbidities is less than optimal in most patients. Incretin-based therapies and Sodium Glucose Cotransporter Inhibitors (SGLTIs) are partially addressing this need in T2D, by inducing weight loss, lowering blood pressure, and providing CV benefit.”

Reducing the occurrence of hypoglycemia, or low blood sugar levels, in insulin-dependent diabetic patients is another vital area in the diabetes space that requires ongoing attention. Currently, all available insulin therapies are associated with the risk of hypoglycemia, despite the fact that new generation insulins such as Novo Nordisk’s Tresiba have lowered the risk.

Dr. Cuaron continues: “The issue of significantly decreased compliance among patients using injectable therapies such as insulin continues to be partially addressed by drug developers. Hypoglycemia is one of the top safety concerns associated with diabetics taking insulin. But most attempts to bring a commercially successful non-injectable insulin to market have been met with failure, as seen with Pfizer’s Exubera.”

The most pressing unmet need in the diabetes space is the development of breakthrough treatments that address the underlying cause of the disease. In T1D, this would be a treatment that  would interfere with either the etiology or the pathogenic processes involved in the eradication of the β  cells. In T2D, the treatment would have to effectively target the root of the disease, insulin resistance.

Dr. Cuaron concludes: “Whether or not a truly curative treatment will be discovered and developed is yet to be seen. In the meantime, developers should continue focusing on tackling the multiple unmet needs that remain in this space.”

ENDS

For more information

To gain access to our latest press releases: GlobalData Media Centre

Analysts available for comment. Please contact the GlobalData Press Office:

email: pr@globaldata.com

EMEA & Americas: +44 (0)207 832 4399

Asia-Pacific: +91 40 6616 6809

GlobalData.com | LinkedIn | Twitter

Notes to Editors

Comments provided by Dr. Jesus Cuaron, Cardiovascular and Metabolic Diseases Managing Analyst for GlobalData

Information taken from GlobalData’s PharmaPoint: Type 2 Diabetes – Global Drug Forecast and Market Analysis to 2026 and GlobalData’s  PharmaPoint: Type 1 Diabetes – Global Drug Forecast and Market Analysis to 2023

About GlobalData
4,000 of the world’s largest companies, including over 70% of FTSE 100 and 60% of Fortune 100 companies, make more timely and better business decisions thanks to GlobalData’s unique data, expert analysis and innovative solutions, all in one platform. GlobalData’s mission is to help our clients decode the future to be more successful and innovative across a range of industries, including the healthcare, consumer, retail, financial, technology and professional services sectors. PR3105

Related Intelligence

Want more Insight like this?

Our interactive subscription platform has the most comprehensive data and analysis in your industry.

Request a Demo

Related Consulting

How can we help your business?

Our consultants are skilled in every specialist market niche to deliver solutions specifically designed for your individual requirements.

Request a Callback

Media Enquiries

If you are a member of the press or media and require any further information, please get in touch, as we’re very happy to help.

Emailpr@globaldata.com
PhoneEMEA: +44 207 832 4399
PhoneAPAC: +91 40 6616 6809
Onlinecontact online

56% of #consumers are concerned about the impact of diet. Join us for more insight @incosmetics #cosmetics #trends… https://t.co/wJOJOqYIJF