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Product Insights
RAF Proto Oncogene Serine, Threonine Protein Kinase (Proto Oncogene c RAF or RAF1 or EC 2.7.11.1) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
RAF proto-oncogene serine/threonine-protein kinase or proto-oncogene c-RAF is an enzyme encoded by the RAF1 gene. The RAF Proto Oncogene Serine, Threonine Protein Kinase (Proto Oncogene c RAF or RAF1 or EC 2.7.11.1) pipeline drugs market research report provides comprehensive information on the RAF Proto Oncogene Serine/Threonine Protein Kinase (Proto Oncogene c RAF or RAF1 or EC 2.7.11.1) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. The report...
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Product Insights
Chondrosarcoma Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Chondrosarcoma is a cancer whose tumor cells produce pure hyaline cartilage that results in abnormal bone and/or cartilage growth. Signs and symptoms include pain in the affected area that may worsen at night or during physical activity, swelling in the painful area, a lump or mass, enlargement of an existing growth, limping, difficulty moving the affected limb, and changes in urination. Treatment includes chemotherapy and radiation therapy. The Chondrosarcoma pipeline drugs market research report provides comprehensive information on the therapeutics...
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Product Insights
Endometrial Cancer Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Endometrial Cancer - Drugs In Development, 2022, provides an overview of the Endometrial Cancer (Oncology) pipeline landscape. Endometrial cancer is cancer that starts in the endometrium, the lining of the uterus (womb). Endometrial cancer is the most common type of uterine cancer. Although the exact cause of endometrial cancer is unknown, increased levels of estrogen appear to play a role. Estrogen helps stimulate the buildup of the lining of the...
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Product Insights
Prostaglandin E2 Receptor EP4 Subtype (Prostanoid EP4 Receptor or PTGER4) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Prostaglandin E2 receptor 4 (EP4) is a prostaglandin receptor encoded by the PTGER4 gene. The activity of the receptor is mediated by G proteins that stimulate adenylate cyclase. It has a relaxing effect on smooth muscle. It plays an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. The Prostaglandin E2 receptor 4 (EP4) pipeline market research report provides comprehensive information on the therapeutics under development for Prostaglandin E2 receptor 4 (EP4), complete with...
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Product Insights
Hairy Cell Leukemia Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Hairy cell leukemia is a rare, slow-growing cancer of the blood in which bone marrow makes too many B cells (lymphocytes), a type of white blood cell that fights infection. Symptoms include fatigue, easy bruising, recurring infections, weakness and weight loss. Risk factors include exposure to radiation, chemicals and saw dust. Treatment includes surgery, chemotherapy and radiation therapy. The Hairy Cell Leukemia pipeline drugs market research report outlays comprehensive information on the Hairy Cell Leukemia targeted therapeutics, complete with analysis...
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Product Insights
Oropharyngeal Cancer Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
The Oropharyngeal Cancer pipeline drugs market research report provides comprehensive information on the therapeutics under development for Oropharyngeal Cancer (Oncology), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history, and the latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Oropharyngeal Cancer...
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Product Insights
Synovial Sarcoma Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Synovial sarcoma is a soft tissue tumor occurring in the biphasic or monophasic type and consisting of epithelial and/or spindle cell components. Symptoms include swelling, mass that may or may not be accompanied by pain and limping or difficulty using legs, arms, hands or feet. The Synovial sarcoma - drugs in development research report provides a comprehensive overview on the therapeutics under development for Synovial sarcoma, complete with analysis by stage of development, drug target, mechanism of action (MoA), route...
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Product Insights
Osteosarcoma Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Osteosarcoma is the most common cancer of the bone that destroys tissue and weakens the bone. It is developed from immature bone cells that normally form new bone tissue. Osteosarcoma Drugs in Development market research report provides comprehensive information on the therapeutics under development for Osteosarcoma, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research...
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Product Insights
Nasopharyngeal Cancer Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Nasopharyngeal cancer is a rare type of head and neck cancer. It starts in the upper part of throat, behind the nose. This area is called the nasopharynx. The risk factors of nasopharyngeal cancer may include Epstein-Barr virus. Symptoms of nasopharyngeal cancer may include blurry or double vision, difficulty speaking, including hoarseness, ear infections that keep coming back, face pain or numbness, headache, hearing loss, ringing in the ears. The Nasopharyngeal cancer - Drugs in Development research report provides a...
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Product Insights
Tyrosine Protein Kinase Mer (Proto Oncogene c Mer or Receptor Tyrosine Kinase MerTK or MERTK or EC 2.7.10.1) Drugs in Development by Therapy Areas and Indications, Stages, MoA, RoA, Molecule Type and Key Players, 2022 Update
The Tyrosine Protein Kinase Mer pipeline market research report provides a comprehensive overview on the therapeutics under development for Tyrosine Protein Kinase Mer, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for...
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Product Insights
Toll Like Receptor 8 (CD288 or TLR8) Development by Therapy Areas and Indications, Stages, MoA, RoA, Molecule Type and Key Players, 2022 Update
Toll-like receptor 8 is a protein encoded by the TLR8 gene. It acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The Toll Like Receptor 8 (CD288 or TLR8) Development market research report provides an in-depth analysis of Toll Like Receptor 8 (CD288 or TLR8) targeted pipeline therapeutics. The report provides comprehensive information on the Toll Like Receptor 8 (CD288 or TLR8) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of...
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Product Insights
Human Cytomegalovirus Envelope Glycoprotein B (gB) Development by Therapy Areas and Indications, Stages, MoA, RoA, Molecule Type and Key Players, 2022 Update
Human Cytomegalovirus envelope glycoprotein B plays an important role in host cell entry and cell to cell virus transmission. It is involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. It interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as post attachment entry receptors. It participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. The Human Cytomegalovirus...
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Product Insights
Chemotherapy Induced Nausea and Vomiting Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update
Chemotherapy induced nausea and vomiting pipeline market research report provides comprehensive information on the therapeutics under development for Chemotherapy Induced Nausea and Vomiting, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for...
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Product Insights
Cyclin Dependent Kinase 4 (Cell Division Protein Kinase 4 or PSK J3 or CDK4 or EC 2.7.11.22) Development by Therapy Areas and Indications, Stages, MoA, RoA, Molecule Type and Key Players, 2022 Update
Cyclin-dependent kinase 4 is an enzyme encoded by the CDK4 gene. Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. Activation of the cyclin-D-CDK4 complex appears to require other factors such as recruitment of the substrate via a substrate recruitment motif, and/or formation of the CDKN1B ternary complex. The Cyclin-dependent kinase 4 - Drugs in Development research report provides a comprehensive overview on...
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Product Insights
Gamma Secretase (EC 3.4.23.) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2021 Update
Gamma Secretase (EC 3.4.23.) Pipeline Drugs Market Report Overview Gamma secretase is a multi-subunit protease complex, itself an integral membrane protein, that cleaves single-pass transmembrane proteins at residues within the transmembrane domain. The most well-known substrate of gamma secretase is amyloid precursor protein, when cleaved by both gamma and beta secretase, produces a short 39-42 amino acid peptide called amyloid beta whose abnormally folded fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease...
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Sector Analysis
Spain Cardiovascular Devices Market Outlook to 2025 – Aortic and Vascular Graft Devices, Atherectomy Devices, Cardiac Assist Devices and Others
GlobalData’s “Spain Cardiovascular Devices Market Outlook to 2025” is a comprehensive databook report, covering key market data on the Spain Cardiovascular Devices market. The databook report provides value (USD), volume (units) and average prices (USD) within market segments – Aortic and Vascular Graft Devices, Atherectomy Devices, Cardiac Assist Devices, Cardiac Rhythm Management Devices, Cardiovascular Prosthetic Devices, Cardiovascular Surgery Devices, Clot Management Devices, Electrophysiology Devices, Interventional Cardiology, Peripheral Vascular Devices and Prosthetic Heart Valves. The Spain Cardiovascular Devices Market report provides...
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Product Insights
Pancreatic Cancer Diagnostic Tests – Medical Devices Pipeline Assessment, 2020
Pancreatic Cancer Diagnostic Tests include assays of mostly antibodies released in response to a pancreatic cancer and cancer-causing proteins. GlobalData's Medical Devices sector report, “Pancreatic Cancer Diagnostic Tests-Medical Devices Pipeline Assessment, 2020" provides comprehensive information about the Pancreatic Cancer Diagnostic Tests pipeline products with comparative analysis of the products at various stages of development and information about the clinical trials which are in progress. The Pancreatic Cancer Diagnostic Tests Pipeline Assessment report provides key information and data related to: Extensive...
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Product Insights
Ovarian Cancer Diagnostic Tests – Medical Devices Pipeline Assessment, 2020
Ovarian Cancer Diagnostic Tests include assays of mostly antibodies released in response to a ovarian cancer and cancer-causing proteins. GlobalData's Medical Devices sector report, “Ovarian Cancer Diagnostic Tests-Medical Devices Pipeline Assessment, 2020" provides comprehensive information about the Ovarian Cancer Diagnostic Tests pipeline products with comparative analysis of the products at various stages of development and information about the clinical trials which are in progress. The Ovarian Cancer Diagnostic Tests Pipeline Assessment report provides key information and data related to: Extensive...
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Product Insights
Colorectal Cancer Diagnostic Tests – Medical Devices Pipeline Assessment, 2020
Colorectal Cancer Diagnostic Tests are used for detection of CRC based on the detection and measurement of cancer-specific biomarker/antibody/antigen present in patient’s sample. GlobalData's Medical Devices sector report, “Colorectal Cancer Diagnostic Tests-Medical Devices Pipeline Assessment, 2020" provides comprehensive information about the Colorectal Cancer Diagnostic Tests pipeline products with comparative analysis of the products at various stages of development and information about the clinical trials which are in progress. The Colorectal Cancer Diagnostic Tests Pipeline Assessment report provides key information and...
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Sector Analysis
Spain Wound Care Management Market Outlook to 2025 – Advanced Wound Management, Compression Therapy, Negative Pressure Wound Therapy (NPWT) and Others
GlobalData’s “Spain Wound Care Management Market Outlook to 2025” is a comprehensive databook report, covering key market data on the Spain Wound Care Management market. The databook report provides value (USD), volume (units) and average prices (USD) within market segments – Advanced Wound Management, Compression Therapy, Negative Pressure Wound Therapy (NPWT), Ostomy Drainage Bags, Oxygen Therapy Devices, Pressure Relief Devices, Surgical Sutures, Tissue Engineered - Skin Substitutes, Traditional Wound Management, Wound Closure Devices and Wound Debridement Devices. The Spain Wound...
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