Alzheimer’s Disease Global Clinical Trials Review, H2, 2016

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GlobalData's clinical trial report, “Alzheimer's Disease Global Clinical Trials Review, H2, 2016" provides an overview of Alzheimer's Disease clinical trials scenario. This report provides top line data relating to the clinical trials on Alzheimer's Disease. Report includes an overview of trial numbers and their average enrollment in top countries conducted across the globe. The report offers coverage of disease clinical trials by region, country (G7 & E7), phase, trial status, end points status and sponsor type. Report also provides prominent drugs for in-progress trials (based on number of ongoing trials). GlobalData Clinical Trial Reports are generated using GlobalData’s proprietary database – Pharma eTrack Clinical trials database. Clinical trials are collated from 80+ different clinical trial registries, conferences, journals, news etc across the globe. Clinical trials database undergoes periodic update by dynamic process.

The report enhances the decision making capabilities and helps to create an effective counter strategies to gain competitive advantage.
Note: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

– The report provides a snapshot of the global clinical trials landscape

– Report provides top level data related to the clinical trials by Region, Country (G7 & E7), Trial Status, Trial Phase, Sponsor Type and End point status

– The report reviews top companies involved and enlists all trials (Trial title, Phase, and Status) pertaining to the company

– The report provides all the unaccomplished trials (Terminated, Suspended and Withdrawn) with reason for unaccomplishment

– The Report provides enrollment trends for the past five years

– Report provides latest news for the past three months

Note: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Reasons to Buy

Assists in formulating key business strategies with regards to investment

Helps in identifying prominent locations for conducting clinical trials which saves time and cost

Provides top level analysis of Global Clinical Trials Market which helps in identifying key business opportunities

Supports understanding of trials count and enrollment trends by country in global therapeutics market

Aids in interpreting the success rates of clinical trials by providing a comparative scenario of completed and uncompleted (terminated, suspended or withdrawn) trials

Facilitates clinical trial assessment of the indication on a global, regional and country level

Note: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Pfizer Inc.
Johnson & Johnson
Eisai Co.
Ltd.
F. Hoffmann-La Roche Ltd.
Eli Lilly and Company
Novartis AG
AstraZeneca Plc
GlaxoSmithKline Plc
AbbVie Inc
Merck & Co.
Inc.

Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 4

Report Guidance 6

Clinical Trials by Region 7

Clinical Trials and Average Enrollment by Country 8

Top Five Countries Contributing to Clinical Trials in Asia-Pacific 11

Top Five Countries Contributing to Clinical Trials in Europe 12

Top Countries Contributing to Clinical Trials in North America 13

Top Countries Contributing to Clinical Trials in Middle East and Africa 14

Top Five Countries Contributing to Clinical Trials in Central and South America 15

Clinical Trials by G7 Countries: Proportion of Alzheimer's Disease to Central Nervous System Clinical Trials 16

Clinical Trials by Phase in G7 Countries 18

Clinical Trials in G7 Countries by Trial Status 19

Clinical Trials by E7 Countries: Proportion of Alzheimer's Disease to Central Nervous System Clinical Trials 21

Clinical Trials by Phase in E7 Countries 23

Clinical Trials in E7 Countries by Trial Status 24

Clinical Trials by Phase 25

In Progress Trials by Phase 26

Clinical Trials by Trial Status 27

Clinical Trials by End Point Status 29

Subjects Recruited Over a Period of Time 30

Clinical Trials by Sponsor Type 31

Prominent Sponsors 32

Top Companies Participating in Alzheimer's Disease Therapeutics Clinical Trials 34

Prominent Drugs 36

Latest Clinical Trials News on Alzheimer's Disease 37

Aug 09, 2016: U.S. FDA Confirms Sufficient Data to Advance Investigational Bace Inhibitor E2609 for Treatment of Early Alzheimer’s Disease to Phase III 37

Aug 02, 2016: Accera Appoints C. Evan Ballantyne as Chief Financial Officer 37

Aug 01, 2016: The results of phase I clinical trial of the Araclon Biotech Alzheimers vaccine support its continuation 38

Jul 29, 2016: Anavex Confirms Data from Phase 2a Study of ANAVEX 2-73 in Alzheimer's Patients Presented at AAIC 2016 38

Jul 27, 2016: TauRx Reports First Phase 3 Results for LMTX 38

Jul 27, 2016: Oryzon Initiates Multiple Ascending Dose Cohorts in ORY-2001 Phase 1 Clinical Trial 40

Jul 27, 2016: vTv Therapeutics Announces Presentation of Phase 2b Azeliragon Results at the 2016 Alzheimer’s Association International Conference 40

Jul 27, 2016: Stemedica Begins First Clinical Trials In The U.S. Using Adult Allogeneic Stem Cells To Treat Alzheimer Disease 41

Jul 27, 2016: Actinogen Medical Announces Landmark Research on Excess Cortisol and Alzheimer's Disease 41

Jul 27, 2016: Anavex Presents 31-Week Efficacy Data from Phase 2a Study of ANAVEX 2-73 in Alzheimer’s Patients at AAIC 2016 42

Jul 27, 2016: Prana Alzheimers disease data features at world leading conference 43

Jul 25, 2016: Alzheon Presents Positive Results of ALZ-801 Clinical Studies that Lead to Advancement to Pivotal Phase 3 Study in Alzheimer Patients with APOE4/4 Homozygous Genotype 43

Jul 24, 2016: Anavex Presents 31-Week Safety Data from Phase 2a Study of ANAVEX 2-73 in Alzheimer's Patients at AAIC 2016 44

Jul 20, 2016: Corium to Present Clinical Data from a Phase 1 Pharmacokinetic Study of Once-Weekly Corplex Donepezil Transdermal System 45

Jul 14, 2016: vTv Therapeutics Announces Phase 2b Azeliragon Data Selected for Oral Presentation at the 2016 Alzheimer's Association International Conference 45

Jul 13, 2016: IntelGenx to Initiate Phase 1 Trial of Montelukast 46

Jul 12, 2016: Anavex to Present at the Alzheimer’s Association International Conference (AAIC) 2016 46

Jul 07, 2016: AC Immune to receive milestone payment for Anti-Tau Antibody moving into Phase 1 trial for Alzheimer’s disease 47

Jun 28, 2016: Intra-Cellular Therapies Announces Initiation of ITI-007-201 Phase 3 Clinical Trial for the Treatment of Agitation in Patients with Dementia, Including Alzheimer’s Disease 47

Jun 22, 2016: AXON Pioneering Tau Vaccine against Alzheimers Started Phase II 48

Jun 21, 2016: Bryostatin, a PKC epsilon Activator, Generates New Synapses Through Accumulation of the Synaptic Anchoring Protein PSD-95 at Neuronal Membranes 48

Jun 14, 2016: New Alzheimers Study Aimed at Preventing or Delaying Symptoms 49

Jun 06, 2016: IL-33 ameliorates Alzheimers-like pathology and cognitive decline 49

Clinical Trial Profile Snapshots 51

Appendix 1069

Abbreviations 1069

Definitions 1069

Research Methodology 1070

Secondary Research 1070

About GlobalData 1071

Contact Us 1071

Disclaimer 1071

Source 1072

Table

Alzheimer's Disease Therapeutics, Global, Clinical Trials by Region, 2016* 7

Alzheimer's Disease Therapeutics, Global, Clinical Trials and Average Enrollment by Top Countries, 2016* 8

Alzheimer's Disease Therapeutics, Global, Clinical Trials In Progress by Top Countries, 2016* 10

Alzheimer's Disease Therapeutics Clinical Trials, Asia-Pacific, Top Five Countries, 2016* 11

Alzheimer's Disease Therapeutics Clinical Trials, Europe, Top Five Countries, 2016* 12

Alzheimer's Disease Therapeutics Clinical Trials, North America, Top Countries, 2016* 13

Alzheimer's Disease Therapeutics Clinical Trials, Middle East and Africa, Top Countries, 2016* 14

Alzheimer's Disease Therapeutics Clinical Trials, Central and South America, Top Five Countries, 2016* 15

Proportion of Alzheimer's Disease to Central Nervous System Clinical Trials, G7 Countries (%), 2016* 16

Alzheimer's Disease Therapeutics, G7 Countries, Clinical Trials by Phase, 2016* 18

Alzheimer's Disease Therapeutics, G7 Countries, Clinical Trials by Trial Status, 2016* 19

Proportion of Alzheimer's Disease to Central Nervous System Clinical Trials, E7 Countries (%), 2016* 21

Alzheimer's Disease Therapeutics, E7 Countries, Clinical Trials by Phase, 2016* 23

Alzheimer's Disease Therapeutics, E7 Countries, Clinical Trials by Trial Status, 2016* 24

Alzheimer's Disease Therapeutics, Global, Clinical Trials by Phase, 2016* 25

Alzheimer's Disease Therapeutics, Global, Clinical Trials In Progress by Phase 2016* 26

Alzheimer's Disease Therapeutics, Global, Clinical Trials by Trial Status, 2016* 27

Alzheimer's Disease Therapeutics Clinical Trials, Global, by End Point Status, 2016* 29

Alzheimer's Disease Therapeutics Clinical Trials, Global, Average Enrollment Target Trends, 2011-2015 30

Alzheimer's Disease Therapeutics Market, Global, Clinical Trials by Sponsor Type, 2016* 31

Alzheimer's Disease Therapeutics Clinical Trials, Global, Key Sponsors, 2016* 32

Alzheimer's Disease Therapeutics Clinical Trials, Global, Top Companies by Phase, 2016* 34

Alzheimer's Disease Therapeutics Clinical Trials, Global, Ongoing Clinical Trials by Prominent Drugs, 2016* 36

Figures

Alzheimer's Disease Therapeutics, Global, Clinical Trials by Region (%), 2016* 7

Alzheimer's Disease Therapeutics, Global, Clinical Trials and Average Enrollment by Top Countries, 2016* 8

Alzheimer's Disease Therapeutics, Global, Clinical Trials In Progress by Top Countries, 2016* 10

Alzheimer's Disease Therapeutics Clinical Trials, Asia-Pacific, Top Five Countries (%), 2016* 11

Alzheimer's Disease Therapeutics Clinical Trials, Europe, Top Five Countries (%), 2016* 12

Alzheimer's Disease Therapeutics Clinical Trials, North America, Top Countries (%), 2016* 13

Alzheimer's Disease Therapeutics Clinical Trials, Middle East and Africa, Top Countries (%), 2016* 14

Alzheimer's Disease Therapeutics Clinical Trials, Central and South America, Top Five Countries (%), 2016* 15

Proportion of Alzheimer's Disease to Central Nervous System Clinical Trials, G7 Countries (%), 2016* 16

Alzheimer's Disease Therapeutics, G7 Countries, Clinical Trials by Phase, 2016* 18

Alzheimer's Disease Therapeutics, G7 Countries, Clinical Trials by Trial Status, 2016* 19

Proportion of Alzheimer's Disease to Central Nervous System Clinical Trials, E7 Countries (%), 2016* 21

Alzheimer's Disease Therapeutics, E7 Countries, Clinical Trials by Phase, 2016* 23

Alzheimer's Disease Therapeutics, E7 Countries, Clinical Trials by Trial Status, 2016* 24

Alzheimer's Disease Therapeutics, Global, Clinical Trials by Phase (%), 2016* 25

Alzheimer's Disease Therapeutics, Global, Clinical Trials In Progress by Phase, 2016* 26

Alzheimer's Disease Therapeutics, Global, Clinical Trials by Trial Status, 2016* 27

Alzheimer's Disease Therapeutics Clinical Trials, Global, by End Point Status, 2016* 29

Alzheimer's Disease Therapeutics Clinical Trials, Global, Average Enrollment Target Trends, 2011-2015 30

Alzheimer's Disease Therapeutics Market, Global, Clinical Trials by Sponsor Type (%), 2016* 31

Alzheimer's Disease Therapeutics Clinical Trials, Global, Key Sponsors, 2016* 32

Alzheimer's Disease Therapeutics Clinical Trials, Global, Top Companies by Phase, 2016* 34

Alzheimer's Disease Therapeutics Clinical Trials, Global, Ongoing Clinical Trials by Prominent Drugs, 2016* 36

GlobalData Methodology 1070

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