Apoptosis Regulator BAX (Bcl 2 Like Protein 4 or BCL2L4 or BAX) Development by Therapy Areas and Indications, Stages, MoA, RoA, Molecule Type and Key Players, 2022 Update

Pages: 44 Published: March 31, 2022 Report Code: GMDGDHC22046TDB

Apoptosis regulator BAX or bcl-2-like protein 4 is a protein is encoded by the BAX gene. It accelerates programmed cell death by antagonizing the apoptosis repressor BCL2. It promotes activation of CASP3, and thereby apoptosis. It undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis under stress conditions.

The Apoptosis regulator BAX – Drugs in Development research report provides a comprehensive overview on the therapeutics under development for Apoptosis regulator BAX, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.  The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.  Additionally, the report provides an overview of key players involved in therapeutic development for Apoptosis regulator BAX and features dormant and discontinued projects.

Key Therapy Areas in the Apoptosis Regulator BAX Pipeline Drugs Market

The key therapy areas in the Apoptosis Regulator BAX pipeline drugs market are Oncology, Cardiovascular, Central nervous System, and Ophthalmology.

Apoptosis Regulator BAX Pipeline Drugs Market, by Therapy Areas

Apoptosis Regulator BAX Pipeline Drugs Market, by Therapy Areas

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Key MoA in the Apoptosis Regulator BAX Pipeline Drugs Market

The key mechanisms of action in the Apoptosis Regulator BAX Pipeline Drugs Market are Apoptosis Regulator BAX Activator, and Apoptosis Regulator BAX Inhibitor.

Apoptosis Regulator BAX Pipeline Drugs Market, by MoA

Apoptosis Regulator BAX Pipeline Drugs Market, by MoA

To get more insights on key MoA, download a free sample report

Apoptosis Regulator BAX Pipeline Drugs Market Segmentation by RoA

The key routes of administration in the Apoptosis Regulator BAX pipeline drugs market are Oral, Intratumor, Intravenous, and Intravenous Bolus.

Apoptosis Regulator BAX Pipeline Drugs Market Analysis, by RoA

Apoptosis Regulator BAX Pipeline Drugs Market Analysis, by RoA

To get more insights on key RoA, download a free sample report

Key Molecule Types in the Apoptosis Regulator BAX Pipeline Drugs Market

The key molecule types in the Apoptosis Regulator BAX pipeline drugs market are Small Molecule, and Synthetic Peptide.

Apoptosis Regulator BAX Pipeline Drugs Market, by Molecule Type

Apoptosis Regulator BAX Pipeline Drugs Market, by Molecule Type

To get more insights on key molecule types, download a free sample report

Major Companies in the Apoptosis Regulator BAX Pipeline Drugs Market

The major companies in the Apoptosis Regulator BAX pipeline drugs market are BAKX Therapeutics Inc, Genervon Biopharmaceuticals LLC, Lytix Biopharma AS, and PHD Biosciences.

Apoptosis Regulator BAX Pipeline Drugs Market, by Major Companies

Apoptosis Regulator BAX Pipeline Drugs Market, by Major Companies

For more company insights, download a free sample report

Apoptosis Regulator BAX Pipeline Drugs Market Overview

Key Targets Oncology, Cardiovascular, Central nervous System, and Ophthalmology
Key Mechanisms of action Apoptosis Regulator BAX Activator, and Apoptosis Regulator BAX Inhibitor
Key Routes of Administration Oral, Intratumor, Intravenous, and Intravenous Bolus
Key molecule types Small Molecule, and Synthetic Peptide
Major companies BAKX Therapeutics Inc, Genervon Biopharmaceuticals LLC, Lytix Biopharma AS, and PHD Biosciences

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of Apoptosis Regulator BAX
  • The pipeline guide reviews pipeline therapeutics for Apoptosis Regulator BAX by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Apoptosis Regulator BAX therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Apoptosis Regulator BAX therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA), and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews the latest news related to pipeline therapeutics for Apoptosis Regulator BAX

Reasons to Buy

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with a potentially strong product portfolio and create effective counter strategies to gain a competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Apoptosis Regulator BAX
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and their most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Apoptosis Regulator BAX pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from the pipeline.

Key Players

BAKX Therapeutics Inc
Genervon Biopharmaceuticals LLC
Lytix Biopharma AS
PHD Biosciences

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Apoptosis Regulator BAX (Bcl 2 Like Protein 4 or BCL2L4 or BAX) – Overview

Apoptosis Regulator BAX (Bcl 2 Like Protein 4 or BCL2L4 or BAX) – Therapeutics Development

Products under Development by Stage of Development

Products under Development by Therapy Area

Products under Development by Indication

Products under Development by Companies

Products under Development by Universities/Institutes

Apoptosis Regulator BAX (Bcl 2 Like Protein 4 or BCL2L4 or BAX) – Therapeutics Assessment

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Apoptosis Regulator BAX (Bcl 2 Like Protein 4 or BCL2L4 or BAX) – Companies Involved in Therapeutics Development

BAKX Therapeutics Inc

Genervon Biopharmaceuticals LLC

Lytix Biopharma AS

PHD Biosciences

Apoptosis Regulator BAX (Bcl 2 Like Protein 4 or BCL2L4 or BAX) – Drug Profiles

BKX-001 – Drug Profile

Product Description

Mechanism Of Action

History of Events

CYD-211 – Drug Profile

Product Description

Mechanism Of Action

History of Events

GM-6 – Drug Profile

Product Description

Mechanism Of Action

History of Events

LTX-401 – Drug Profile

Product Description

Mechanism Of Action

History of Events

Small Molecule to Activate Apoptosis Regulator BAX for Lung Cancer – Drug Profile

Product Description

Mechanism Of Action

Small Molecule to Inhibit BAX for Myocardial Infarction – Drug Profile

Product Description

Mechanism Of Action

Small Molecules to Inhibit BAX for Ophthalmology – Drug Profile

Product Description

Mechanism Of Action

SMBA-1 – Drug Profile

Product Description

Mechanism Of Action

Apoptosis Regulator BAX (Bcl 2 Like Protein 4 or BCL2L4 or BAX) – Dormant Products

Apoptosis Regulator BAX (Bcl 2 Like Protein 4 or BCL2L4 or BAX) – Product Development Milestones

Featured News & Press Releases

Feb 15, 2022: Lytix Biopharma granted 3 MNOK from Oslo Regional Research Fund

Feb 26, 2018: Genervon Presents Innovative CNS Drug Candidate at 2018 BIO CEO & Investor Conference

Dec 08, 2017: GM604 Is a Multi-Target Regulator That Provides a Novel Treatment Strategy for ALS

Apr 06, 2017: Lytix Biopharma presents poster on LTX-401 at AACR in Washington April 2017

Mar 23, 2017: Confidential Data from Genervon ALS Phase 2A Clinical Trial Were Released and Published

Jan 10, 2017: Genervon Releases ALS, PD and AD Disease­ Associated Gene Lists Modulated by GM6 and Encourages Researchers to Explore New Discoveries beyond Single Target Drug Development Paradigm

Dec 27, 2016: ALS and Alzheimer’s disease bioinformatics reports confirm GM6’s role as regulator of disease-relevant pathways

Sep 21, 2016: Lytix Biopharma develops second generation oncolytic molecules for deep seated tumors

Jun 06, 2016: GENERVON GM604 received EUs orphan drug designation to treat ALS

May 23, 2016: ALS Patients from Around the World Responding Well to Genervons GM604

May 03, 2016: GM604 to Be Granted “Orphan Drug” Status in Europe

Sep 22, 2015: Genervon GM604 Reduced TDP-43 Protein Aggregates and Slowed Down ALS Progression

Jun 29, 2015: Genervon Filed Patent for Using GM604 Modulations of ALS Disease Biomarkers Showing Homeostasis, Leading to Prognosis and Therapeutic Treatment for ALS Disease

Apr 17, 2015: Amyotrophic Lateral Sclerosis Statement; FDA

Jan 08, 2015: Genervon Announces ALS Compassionate Use Results

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

List of Tables

List of Tables

Number of Products under Development by Stage of Development, 2022

Number of Products under Development by Therapy Areas, 2022

Number of Products under Development by Indication, 2022

Number of Products under Development by Companies, 2022

Products under Development by Companies, 2022

Number of Products under Investigation by Universities/Institutes, 2022

Products under Investigation by Universities/Institutes, 2022

Number of Products by Stage and Mechanism of Actions, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Pipeline by BAKX Therapeutics Inc, 2022

Pipeline by Genervon Biopharmaceuticals LLC, 2022

Pipeline by Lytix Biopharma AS, 2022

Pipeline by PHD Biosciences, 2022

Dormant Projects, 2022

List of Figures

List of Figures

Number of Products under Development by Stage of Development, 2022

Number of Products under Development by Therapy Areas, 2022

Number of Products under Development by Top 10 Indications, 2022

Number of Products by Mechanism of Actions, 2022

Number of Products by Stage and Mechanism of Actions, 2022

Number of Products by Routes of Administration, 2022

Number of Products by Stage and Routes of Administration, 2022

Number of Products by Molecule Types, 2022

Number of Products by Stage and Molecule Types, 2022

Frequently Asked Questions

The key therapy areas in the Apoptosis Regulator BAX pipeline drugs market are Oncology, Cardiovascular, Central nervous System, and Ophthalmology.

The key mechanisms of action in the Apoptosis Regulator BAX pipeline drugs market are Apoptosis Regulator BAX Activator, and Apoptosis Regulator BAX Inhibitor.

The key routes of administration in the Apoptosis Regulator BAX pipeline drugs market are Oral, Intratumor, Intravenous, and Intravenous Bolus.

The key molecule types in the Apoptosis Regulator BAX pipeline drugs market are Small Molecule, and Synthetic Peptide.

The major companies in the Apoptosis Regulator BAX pipeline drugs market are BAKX Therapeutics Inc, Genervon Biopharmaceuticals LLC, Lytix Biopharma AS, and PHD Biosciences.

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