Axial Spondyloarthritis (axSpA) Marketed and Pipeline Drugs Assessment, Clinical Trials and Competitive Landscape

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Axial Spondyloarthritis, a chronic autoinflammatory disorder of the sacroiliac joints and spine, causes can occur with symptoms like fatigue​, spinal pain​, arthralgia (joint pain) or swelling​, enthesitis (inflammation of the entheses)​, and morning stiffness​. There are millions of diagnosed prevalent cases of axial Spondyloarthritis worldwide.

The Axial Spondyloarthritis marketed and pipeline drugs market research report includes an assessment of the disease epidemiology, leading marketed products with sales forecast, pricing and reimbursement, late-stage pipeline products with phase transition success rate (PTSR), and likelihood of approval (LoA) for axSpA.​ The report also analyzes the clinical and commercial landscapes of axSpA, as well as an assessment of deals, future market catalysts, key market players, and the future competitive environment.​

Leading Marketed Drugs for Axial Spondyloarthritis

Adalimumab, Etanercept, Golimumab, Ixekizumab, and Upadacitinib are some of the primary drugs for Axial Spondyloarthritis.​ AbbVie – Humira, Novartis – Cosentyx, and Pfizer – Enbrel are some of the key brands involved in the production of leading marketed drugs in Axial Spondyloarthritis.

Axial Spondyloarthritis Marketed Drugs Segmentation by Mechanism of Action

The majority of marketed drugs for Axial Spondyloarthritis are receptor agonists and enzyme inhibitors. Receptor antagonist, biological factor inhibitor, and ion channel blocker are some of the primary mechanisms of actions in the marketed drugs for Axial Spondyloarthritis.

Axial Spondyloarthritis Marketed Drugs Analysis, by Mechanism of Action, 2022 (%)

Axial Spondyloarthritis Marketed Drugs Analysis, by Mechanism of Action

For more MoA insights into the Axial Spondyloarthritis marketed drugs, download a free report sample

Axial Spondyloarthritis Marketed Drugs Segmentation by Molecule Type

The majority of the marketed drugs for Axial Spondyloarthritis are small molecules. Biologic is another significant molecule type in the marketed drugs for Axial Spondyloarthritis.

Axial Spondyloarthritis Marketed Drugs Analysis, by Molecule type, 2022 (%)

Axial Spondyloarthritis Marketed Drugs Analysis, by Molecule type

For more molecule type insights into the Axial Spondyloarthritis marketed drugs, download a free report sample

Axial Spondyloarthritis Marketed Drugs Segmentation by Routes of Administration

More than half of the marketed drugs for Axial Spondyloarthritis utilize an oral route of administration. The other four RoA in the marketed drugs for Axial Spondyloarthritis are injection, inhalational, topical, and suppository.

Axial Spondyloarthritis Marketed Drugs Analysis, by Routes of Administration, 2022 (%)

Axial Spondyloarthritis Marketed Drugs Analysis, by Routes of Administration

For more RoA insights into the Axial Spondyloarthritis marketed drugs, download a free report sample

Leading Pipeline Drugs for Axial Spondyloarthritis

In the current axSpA late-stage clinical development, drugs are targeting IL-17A or IL-17A/F and JAK1, with biosimilars for anti-TNF agents also in the pipeline.​ Upadacitinib ER, Adalimumab biosimilar, and Brodalumab are some of the primary pipeline drugs for Axial Spondyloarthritis.

Axial Spondyloarthritis Pipeline Drugs Segmentation by Mechanism of Action

Most of the pipeline drugs undergoing development for axSpA with a known mechanism of action are biological factor inhibitors. ​Receptor antagonists, enzyme inhibitors, and receptor agonists are other significant mechanisms of action in the axSpA pipeline drugs.

Axial Spondyloarthritis Pipeline Drugs Analysis, by Mechanisms of Action, 2022 (%)

Axial Spondyloarthritis Pipeline Drugs Analysis, by Mechanisms of Action

For more MoA insights into the Axial Spondyloarthritis pipeline drugs, download a free report sample

Axial Spondyloarthritis Pipeline Drugs Segmentation by Molecule Type

Currently the majority of drugs in various development stages are biologics. Small molecule and Oligonucleotide are the other two molecule types found in pipeline drugs in Axial Spondyloarthritis.

Axial Spondyloarthritis Pipeline Drugs Analysis, by Molecule Types, 2022 (%)

Axial Spondyloarthritis Pipeline Drugs Analysis, by Molecule Types

For more molecule type insights into the Axial Spondyloarthritis pipeline drugs, download a free report sample

Axial Spondyloarthritis Pipeline Drugs Segmentation by Routes of Administration

Of the pipeline drugs undergoing development for Axial Spondyloarthritis with a known route of administration, injectable, topical, and oral therapies are all common. Majority of the Axial Spondyloarthritis pipeline drugs are injectables.

Axial Spondyloarthritis Pipeline Drugs Analysis, by Routes of Administration, 2022 (%)

Axial Spondyloarthritis Pipeline Drugs Analysis, by Routes of Administration

For more RoA insights into the Axial Spondyloarthritis pipeline drugs, download a free report sample

Top Sponsors in the Axial Spondyloarthritis Marketed and Pipeline Drugs Market

Novartis has sponsored the highest number of clinical trials of all the clinical trials in Axial Spondyloarthritis that were initiated over the past 10 years. UCB SA, Pfizer Inc, and Biocad are some of the top sponsors in the clinical trials of Axial Spondyloarthritis marketed and pipeline drugs market.

Axial Spondyloarthritis Marketed Drugs Report Overview

Key Mechanisms of Action (Marketed Drugs) Receptor Agonist, Receptor Antagonist, Enzyme Inhibitor, Biological Factor Inhibitor, and Ion Channel Blocker
Analysis Year 2022
Key Routes of Administration (Marketed Drugs) Injections, Oral, Topical, Inhalational, And Suppository
Key Molecule Types (Marketed Drugs) Small Molecule, and Biologic

Axial Spondyloarthritis Pipeline Drugs Market Report Overview

Key Mechanisms of Action (Pipeline Drugs) Receptor Antagonists, Biological Factor Inhibitors, Enzyme Inhibitors, and Receptor Agonists
Analysis Year 2022
Key Routes of Administration (Pipeline Drugs) Injection, Topical, and Oral
Key Molecule Types (Pipeline Drugs) Small Molecule, Oligonucleotide, and Biologic
Top Sponsors Novartis, UCB SA, Pfizer Inc, and Biocad

Axial Spondyloarthritis Marketed Drugs Market MoA Overview ( No of Drugs in the Pipeline, 2022)

  • Axial Spondyloarthritis Marketed Drugs Market MoA Overview ( No of Drugs in the Pipeline, 2022)

Axial Spondyloarthritis Marketed Drugs Market RoA Overview ( No of Drugs in the Pipeline, 2022)

  • Injections
  • Oral
  • Topical
  • Inhalational
  • Suppository

Axial Spondyloarthritis Marketed Drugs Market Molecule Types Overview ( No of Drugs in the Pipeline, 2022)

  • Small Molecule
  • Biologic

Axial Spondyloarthritis Pipeline Drugs Market MoA Overview ( No of Drugs in the Pipeline, 2022)

  • Receptor Antagonists
  • Biological Factor Inhibitors
  • Enzyme Inhibitors
  • Receptor Agonists

Axial Spondyloarthritis Pipeline Drugs Market RoA Overview ( No of Drugs in the Pipeline, 2022)

  • Injection
  • Topical
  • Oral

Axial Spondyloarthritis Pipeline Drugs Market Molecule Types Overview ( No of Drugs in the Pipeline, 2022)

  • Small Molecule
  • Oligonucleotide
  • Biologic

Scope

GlobalData’s “Axial Spondyloarthritis (axSpA) Marketed and Pipeline Drugs Assessment, Clinical Trials and Competitive Landscape” combines data from the Pharma Intelligence Center with in-house analyst expertise to provide a competitive assessment of the disease marketplace.

Components of the report include:

  • Disease Landscape
  • Disease Overview
  • Epidemiology Overview
  • Treatment Overview
  • Marketed Products Assessment
  • Breakdown by Mechanism of Action, Molecule Type, Route of Administration
  • Product Profiles with Sales Forecast
  • Pricing and Reimbursement Assessment
  • Retail or Manufacturer Price of Products
  • Time to Pricing and Time to Reimbursement
  • Pipeline Assessment
  • Breakdown by Development Stage, Mechanism of Action, Molecule Type, Route of Administration
  • Product Profiles with Sales Forecast
  • Late-to-mid-stage Pipeline Drugs
  • Phase Transition Success Rate and Likelihood of Approval
  • Clinical Trials Assessment
  • Breakdown of Trials by Phase, Status, Virtual Components, Sponsors, Geography, and Endpoint Status
  • Enrolment Analytics, Site Analytics, Feasibility Analysis
  • Deals Landscape
  • Mergers, Acquisitions, and Strategic Alliances by Region
  • Overview of Recent Deals
  • Commercial Assessment
  • Key Market Players
  • Future Market Catalysts

Reasons to Buy

  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the axSpA market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global axSpA market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and strategic partnerships.

Table of Contents

1 Preface

1.1 Contents

1.2 Report Scope

1.3 List of Tables and Figures

1.4 Abbreviations

2 Key Findings

3 Disease Landscape

3.1 Disease Overview

3.2 Epidemiology Overview

3.3 Treatment Overview

4 Marketed Drugs Assessment

4.1 Leading Marketed Drugs

4.2 Overview by Mechanism of Action

4.3 Overview by Route of Administration

4.4 Marketed Drugs Profiles and Sales Forecasts

5 Pricing and Reimbursement Assessment

5.1 Manufacturer Price

5.2 Time to Pricing and Reimbursement

6 Pipeline Drugs Assessment

6.1 Phase III Pipeline Drugs

6.2 Overview by Development Stage

6.3 Overview by Molecule Type

6.4 Overview by Mechanism of Action

6.5 Overview by Route of Administration

6.6 Drug Specific Phase Transition Success Rate (PTSR) and Likelihood of Approval (LoA)

6.7 Therapy Area and Indication-specific PTSR and LoA

7 Clinical Trials Assessment

7.1 Historical Overview

7.2 Overview by Phase

7.3 Overview by Status

7.4 Overview by Phase for Ongoing and Planned Trials

7.5 Trials with Virtual Components

7.6 Geographic Overview

7.7 Single-Country and Multinational Trials by Region

7.8 Top 20 Sponsors with Breakdown by Phase

7.9 Top 20 Sponsors with Breakdown by Status

7.10 Overview by Endpoint Status

7.11 Overview by Race and Ethnicity

7.12 Enrollment Data

7.13 Top 20 countries for Trial Sites

7.14 Top 20 Sites Globally

7.15 Feasibility Analysis – Geographic Overview

7.16 Feasibility Analysis – Benchmark Models

8 Deals Landscape

8.1 Mergers, Acquisitions, and Strategic Alliances by Region

8.2 Recent Mergers, Acquisitions, and Strategic Alliances

9 Commercial Assessment

9.1 Key Market Players

10 Future Market Catalysts

11 Appendix

11.1 Methodology

11.2 Methodology – Sales Forecast

11.3 Methodology – Pricing and Reimbursement

11.4 Methodology – PTSR and LoA Analysis

11.5 About the Authors

11.6 Contact Us

11.7 Disclaimer

Frequently asked questions

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