Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

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Chronic myeloid leukemia (CML), also known as chronic myelogenous leukemia, is a type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood. Risk factors for CML include high-dose radiation, age, and gender. Symptoms include weakness, fatigue, night sweats, weight loss, fever, bone pain, an enlarged spleen, and pain or a sense of fullness in the belly. Treatment includes radiation therapy, blood cell transplantation, and chemotherapy.

The CML pipeline drugs market research report provides comprehensive information on the therapeutics under development for CML, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history, and the latest news and press releases. Additionally, the report offers an overview of key players involved in therapeutic development for CML and features dormant and discontinued projects.

CML Pipeline Drugs Market Segmentation by Targets

Some of the targets of the CML pipeline drugs market are Bcr-Abl Tyrosine Kinase, Cells Expressing B Lymphocyte Antigen CD19, Cells Expressing B Cell Receptor CD22, Cells Expressing Interleukin 3 Receptor Subunit Alpha, CD3, Cells Expressing Mast/Stem Cell Growth Factor Receptor Kit, Cells Expressing Myeloid Cell Surface Antigen CD33, Cells Expressing Wilms Tumor Protein, and others.

CML Pipeline Drugs Market Analysis, by Targets

CML Pipeline Drugs Market Analysis, by Targets

For more CML pipeline drugs market target insights, download a free report sample

CML Pipeline Drugs Market Segmentation by Mechanisms of Actions

Some of the key mechanisms of action of the CML pipeline drugs market are Bcr-Abl Tyrosine Kinase Inhibitor, Cytotoxic To Cells Expressing B Lymphocyte Antigen CD19, Cytotoxic To Cells Expressing B Cell Receptor CD22, Cytotoxic To Cells Expressing Interleukin 3 Receptor Subunit Alpha, CD3 Agonist, Cytotoxic To Cells Expressing Mast/Stem Cell Growth Factor Receptor Kit, Cytotoxic To Cells Expressing Myeloid Cell Surface Antigen CD33, Cytotoxic To Cells Expressing Wilms Tumor Protein, and others.

CML Pipeline Drugs Market Analysis, by Mechanism of Action

CML Pipeline Drugs Market Analysis, by Mechanism of Action

For more mechanisms of action insights into the CML pipeline drugs market, download a free report sample

CML Pipeline Drugs Market Segmentation by Routes of Administration

The key routes of administration in the CML pipeline drugs market are oral, intravenous, parenteral, subcutaneous, intraperitoneal, intradermal, intralesional, intramuscular, and others.

CML Pipeline Drugs Market Analysis, by Routes of Administration

CML Pipeline Drugs Market Analysis, by Routes of Administration

For more routes of administration insights into the CML pipeline drugs market, download a free report sample

CML Pipeline Drugs Market Segmentation by Molecule Types

The molecule types in the CML pipeline drugs market are Small Molecule, Cell Therapy, Gene-Modified Cell Therapy, Monoclonal Antibody Conjugated, Monoclonal Antibody, Fusion Protein, and others.

CML Pipeline Drugs Market Analysis, by Molecule Types

CML Pipeline Drugs Market Analysis, by Molecule TypesFor more molecule type insights into the CML pipeline drugs market, download a free report sample

CML Pipeline Drugs Market - Competitive Landscape

Some of the key companies in the CML pipeline drugs market are Ascentage Pharma Group International, Bristol-Myers Squibb Co, Millennium Pharmaceuticals Inc, Pfizer Inc, AbbVie Inc, Handa Pharmaceuticals LLC, Ilyang Pharmaceutical Co Ltd, Nanocopoeia LLC, and others.

CML Pipeline Drugs Market Analysis, by Companies

CML Pipeline Drugs Market Analysis, by Companies

To know more about the CML pipeline drugs market companies, download a free report sample

CML Pipeline Drugs Market Report Overview

Key Targets Bcr-Abl Tyrosine Kinase, Cells Expressing B Lymphocyte Antigen CD19, Cells Expressing B Cell Receptor CD22, Cells Expressing Interleukin 3 Receptor Subunit Alpha, CD3, Cells Expressing Mast/Stem Cell Growth Factor Receptor Kit, Cells Expressing Myeloid Cell Surface Antigen CD33, Cells Expressing Wilms Tumor Protein, and Others
Key Mechanisms of Action Bcr-Abl Tyrosine Kinase Inhibitor, Cytotoxic To Cells Expressing B Lymphocyte Antigen CD19, Cytotoxic To Cells Expressing B Cell Receptor CD22, Cytotoxic To Cells Expressing Interleukin 3 Receptor Subunit Alpha, CD3 Agonist, Cytotoxic To Cells Expressing Mast/Stem Cell Growth Factor Receptor Kit, Cytotoxic To Cells Expressing Myeloid Cell Surface Antigen CD33, Cytotoxic To Cells Expressing Wilms Tumor Protein, and Others
Key Routes of Administration Oral, Intravenous, Parenteral, Subcutaneous, Intraperitoneal, Intradermal, Intralesional, Intramuscular, and Others
Key Molecule Types Small Molecule, Cell Therapy, Gene-Modified Cell Therapy, Monoclonal Antibody Conjugated, Monoclonal Antibody, Fusion Protein, and Others
Key Companies Ascentage Pharma Group International, Bristol-Myers Squibb Co, Millennium Pharmaceuticals Inc, Pfizer Inc, AbbVie Inc, Handa Pharmaceuticals LLC, Ilyang Pharmaceutical Co Ltd, Nanocopoeia LLC

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of CML.
  • The pipeline guide reviews pipeline therapeutics for CML by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration to discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in CML therapeutics and enlists CML in their major and minor projects.
  • The pipeline guide evaluates CML therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA), and molecule type.
  • The pipeline guide encapsulates CML in the dormant and discontinued pipeline projects.
  • The pipeline guide reviews the latest news related to pipeline therapeutics for CML

Reasons to Buy

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with a potentially strong product portfolio and create effective counterstrategies to gain a competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for CML.
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and their most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding the CML pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understanding from the know-how what drove them from the pipeline.

A. Menarini Industrie Farmaceutiche Riunite Srl
AbbVie Inc
Actinium Pharmaceuticals Inc
Arromax Pharmatech Co Ltd
Ascentage Pharma Group International
Astex Pharmaceuticals Inc
Aurigene Discovery Technologies Ltd
Autolus Therapeutics Plc
Bio-Path Holdings Inc
BioLineRx Ltd
Bristol-Myers Squibb Co
Celularity Inc
Chimeric Therapeutics Ltd
CSPC Pharmaceutical Group Ltd
Enliven Therapeutics Inc
Escend Pharmaceuticals Inc
Eureka Therapeutics Inc
ExCellThera Inc
F. Hoffmann-La Roche Ltd
Fate Therapeutics Inc
Fusion Pharmaceuticals US Inc
Gamida Cell Ltd
GT Biopharma Inc
Handa Pharmaceuticals LLC
HEC Pharma Co Ltd
Helocyte Biosciences Inc
HighPass Bio Inc
Housey Pharmaceutical Research Laboratories LLC
iCell Gene Therapeutics LLC
Ilyang Pharmaceutical Co Ltd
ImmunityBio Inc
ImmunoForge Co Ltd
ImmunoGen Inc
IN8bio Inc
Inhibikase Therapeutics Inc
InnoCure Therapeutics Inc
Johnson & Johnson
Kartos Therapeutics Inc
Kiadis Pharma NV
MAA Laboratories Inc
MacroGenics Inc
Mana Therapeutics Inc
MedPacto Inc
Millennium Pharmaceuticals Inc
Nanjing Sanhome Pharmaceutical Co Ltd
Nanocopoeia LLC
Nemucore Medical Innovations Inc
Nohla Therapeutics Inc
Novartis AG
Novelty Nobility Inc
Ono Pharmaceutical Co Ltd
Otsuka Pharmaceutical Co Ltd
Pfizer Inc
Pharma Mar SA
PharmaEssentia Corp
PRISM Pharma Co Ltd
PYC Therapeutics Ltd
Sanofi
Shenogen Pharma Group Ltd
Shenzhen Targetrx Inc
Sun Pharma Advanced Research Company Ltd
Synactix Pharmaceuticals Inc
Takeda Pharmaceutical Co Ltd
Telix Pharmaceuticals Ltd
Terns Pharmaceuticals Inc
TotalClarity Inc
Vincerx Pharma Inc
VioQuest Pharmaceuticals Inc (Inactive)
Xencor Inc
Xspray Pharma AB

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) – Overview

Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) – Therapeutics Development

Pipeline Overview

Pipeline by Companies

Pipeline by Universities/Institutes

Products under Development by Companies

Products under Development by Universities/Institutes

Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) – Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) – Companies Involved in Therapeutics Development

Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) – Drug Profiles

Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) – Dormant Projects

Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) – Discontinued Products

Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) – Product Development Milestones

Featured News & Press Releases

Sep 21, 2022: Ascentage Pharma announces phase I/II data of olverembatinib (HQP1351) published in the Journal of Hematology & Oncology, further validating the drug’s best-in-class potential

Aug 31, 2022: Scemblix, a first-in-class CML treatment with new mechanism of action approved in Canada

Aug 29, 2022: Novartis Scemblix, with novel mechanism of action, approved by the European Commission for adult patients with chronic myeloid leukemia

Aug 26, 2022: Inhibikase Therapeutics announces FDA clearance of Investigational New Drug Application for IkT-001Pro for the Treatment of Chronic Myelogenous Leukemia

Jul 22, 2022: Ascentage Pharma and Tanner Pharma Group initiate a global innovative Named Patient Program

Jul 21, 2022: Ascentage Pharma announces clinical trial application for Olverembatinib (HQP1351) approved in Canada

Jul 19, 2022: The National Medical Products Adminstration accepted and granted priortiy review designation to a new drug application for olverembatinib for the treatment of drug-resistant chornic myeloid leukemia

Jun 30, 2022: First STAMP (specifically targeting the abl myristoyl pocket) inhibitor for treatment for chronic myeloid leukaemia (CML), Scemblix (asciminib) receives NICE final draft recommendation in Great Britain

Jun 24, 2022: Novartis receives positive CHMP opinion for Scemblix, a novel treatment for adult patients with chronic myeloid leukemia

Jun 07, 2022: Novartis Scemblix, with novel mechanism of action, shows superior, long-term efficacy and consistent tolerability in 96-week follow-up of chronic myeloid leukemia trial

Jan 05, 2022: The first commercial insurance landed in Huzhou, and Ascentage Pharma’s Nerike was included in the “Zheli Medical Insurance South Taihu Health Insurance”

Dec 14, 2021: ASH 2021 | Ascentage Pharma releases long-term clinical data of olverembatinib (HQP1351) in oral presentation demonstrating efficacy and safety

Dec 11, 2021: Novartis Scemblix demonstrates sustained response rate in 48-week follow-up in patients with chronic myeloid leukemia

Nov 25, 2021: Ascentage Pharma announces approval by NMPA for China’s first approved third-generation BCR-ABL TKI HQP1351 (Olverembatinib)

Nov 22, 2021: Ascentage Pharma’s olverembatinib granted orphan designation by the European Commission for the treatment of chronic myeloid leukemia

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Products under Development for Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia), 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Universities/Institutes, 2022

Products under Development by Companies, 2022

Products under Development by Universities/Institutes, 2022

Number of Products by Stage and Target, 2022

Number of Products by Stage and Mechanism of Action, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) – Dormant Projects, 2022

Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) – Discontinued Products, 2022

Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) – Discontinued Products, 2022 (Contd..1)

Figures

List of Figures

Number of Products under Development for Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia), 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Universities/Institutes, 2022

Number of Products by Top 10 Targets, 2022

Number of Products by Stage and Top 10 Targets, 2022

Number of Products by Top 10 Mechanism of Actions, 2022

Number of Products by Stage and Top 10 Mechanism of Actions, 2022

Number of Products by Top 10 Routes of Administration, 2022

Number of Products by Stage and Top 10 Routes of Administration, 2022

Number of Products by Top 10 Molecule Types, 2022

Number of Products by Stage and Top 10 Molecule Types, 2022

Frequently asked questions

  • What are the key targets of the CML pipeline drugs market?

    Some of the targets of the CML pipeline drugs market are Bcr-Abl Tyrosine Kinase, Cells Expressing B Lymphocyte Antigen CD19, Cells Expressing B Cell Receptor CD22, Cells Expressing Interleukin 3 Receptor Subunit Alpha, CD3, Cells Expressing Mast/Stem Cell Growth Factor Receptor Kit, Cells Expressing Myeloid Cell Surface Antigen CD33, Cells Expressing Wilms Tumor Protein, and others.

  • What are the key mechanisms of action in the CML pipeline drugs market?

    Some of the mechanisms of action of the CML pipeline drugs market are Bcr-Abl Tyrosine Kinase Inhibitor, Cytotoxic To Cells Expressing B Lymphocyte Antigen CD19, Cytotoxic To Cells Expressing B Cell Receptor CD22, Cytotoxic To Cells Expressing Interleukin 3 Receptor Subunit Alpha, CD3 Agonist, Cytotoxic To Cells Expressing Mast/Stem Cell Growth Factor Receptor Kit, Cytotoxic To Cells Expressing Myeloid Cell Surface Antigen CD33, Cytotoxic To Cells Expressing Wilms Tumor Protein, and others.

  • What are the key routes of administration in the CML pipeline drugs market?

    The key routes of administration in the CML pipeline drugs market are oral, intravenous, parenteral, subcutaneous, intraperitoneal, intradermal, intralesional, intramuscular, and others.

  • What are the key molecule types in the CML pipeline drugs market?

    The molecule types in the CML pipeline drugs market are Small Molecule, Cell Therapy, Gene-Modified Cell Therapy, Monoclonal Antibody Conjugated, Monoclonal Antibody, Fusion Protein, and others.

  • Which are the leading companies in the CML pipeline drugs market?

    Some of the key companies in the CML pipeline drugs market are Ascentage Pharma Group International, Bristol-Myers Squibb Co, Millennium Pharmaceuticals Inc, Pfizer Inc, AbbVie Inc, Handa Pharmaceuticals LLC, Ilyang Pharmaceutical Co Ltd, Nanocopoeia LLC, and others.

Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update standard reports
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