Competitor Landscape: Non-alcoholic Steatohepatitis (NASH)

Pages: 52 Published: November 30, 2018 Report Code: GDHC062SP

Executive Summary: Contains analysis of key market events that have occurred during the previous month and which have impacted Sociable Pharma’s view of the disease landscape
Landscape Updates: ‘Order of Entry’ analysis, detailing timeline forecasts for each drug in Phase II development or higher; Timeline forecasts for each approved product’s lifecycle management initiatives; ‘Market Entry’ & ‘Direction of Travel’ positioning analysis for pipeline & currently approved therapies
Pipeline Landscape: An overview of pipeline candidates, containing snapshots of current development status; Expected drug-specific events & milestones until YE 2019
Approved Product Landscape: An overview of pipeline candidates, containing snapshots of current development status; Expected drug-specific events & milestones until YE 2019

Scope

The briefing is based on Sociable Pharma’s analysis of clinical trial data from company announcements (press releases, earnings calls) and clinical trial databases (clinicaltrials.gov)

Sociable Pharma applies disease & drug specific assumptions in order to forecast US & EU approvals for drugs in Phase II development, or higher – these are outlined in the report Appendix

Forecasts are presented in pipeline forecast figures & detailed tables

‘Market Entry’ & ‘Direction of Travel’ positioning analysis for pipeline & currently approved therapies is also provided

Key Highlights

Phase II NCT02787304 trial has been discontinued, and the future of SHP626 (volixibat) in NASH is currently uncertain

Topline results for Phase IIb NATIVE trial of lanifibranor in NASH are currently expected in H1 2020 (delayed from the original schedule of mid-2018 due to slow patient enrollment)

Medicinova will likely initiate a Phase IIb trial for MN-001 with biopsy-based endpoints, which could begin at any time

Reasons to Buy

Provides details on forecast US & EU approvals for pipeline drugs in Phase II development or higher

Includes potential positioning strategies that companies may adopt for their novel assets once they are approved & launched in the market

Reviews ongoing lifecycle management strategies for existing players in the market

A detailed methodology allows you to understand the forecast assumptions made, enabling cross comparison with your own internal forecasts

Key Players

Afimmune
Akarna Therapeutics
Akero Therapeutics
Albireo
Allergan
Allergan (acquired from
Ardelyx
Arisaph
AstraZeneca
BHV Pharma Inc
Bird Rock Bio/Janssen
BMS
Boehringer Ingelheim
Can-Fite BioPharma
Celgene
Cempra
Cerenis Therapeutics
ChemomAb
Cirius Therapeutics
CohBar
ConSynance Therapeutics
CymaBay Therapeutics
DeuteRx
Dr. Falk Pharma GmbH
DURECT Corporation
Eli Lilly
Enanta
Galectin Therapeutics
Galmed
Gemcabene
Genfit
Gilead
GRI Bio
HighTide Biopharma
Immune Pharmaceuticals Inc.
Immuron
Intercept
INVENT Pharmaceuticals
Inventiva
Ionis Pharma-ceuticals
Janssen
Madrigal
MediciNova
Metacrine
Mitsubishi Tanabe
Naia
NGM Biopharmaceuticals
Nitto Denko
NorthSea Therapeutics
Novartis
Novo Nordisk
NuSirt BioPharma
Oramed
Pfizer
Poxel
Sanofi
Second Genome
Shire
Sinew Pharma
Sucampo Pharmaceuticals
Synairgen
Taiwan Pharmaceuticals
Teva
Tiziana Life Sciences
Valbiotis
Viking Therapeutics
Virobay
Zafgen
Zydus Discovery

Table of Contents

• Introduction to Sociable Pharma’s ‘Competitor Landscape’

• Executive Summary (Go to Section)

– Key Events & Landscape Updates

• Landscape Updates (Go to Section)

– Order of Entry

– Key Competitor Market Entry Strategies

– Lifecycle Development

– Key Competitor ‘Direction of Travel’

• Pipeline Landscape (Go to Section)

– Pipeline Summary

• Appendix (Go to Section)

– Early Stage Pipeline ‘Watch List’

– Assumptions, Glossary & Abbreviations, and Notes

– Contact Details

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