Diffuse Large B-Cell Lymphoma (DLBCL) Marketed and Pipeline Drugs Assessment, Clinical Trials and Competitive Landscape

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Diffuse Large B-Cell Lymphoma (DLBCL) Marketed and Pipeline Drugs Report Overview

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin’s lymphoma (NHL). The subtypes of NHL are defined by the cell of origin, the location involved, and the extensive histopathologic, immunophenotypic, and genetic criteria. B-cell NHLs generally arise in the lymphoid tissue, such as the lymph nodes, bone marrow, thymus, and spleen, and can disseminate to distant sites such as the lung or brain in the later stages of the disease.

Key Mechanism of Action (Marketed) ·       Cytotoxic

·       Receptor Agonist

·       Receptor Antagonist

·       Protein and Peptide Inhibitor

·       Genes, Nucleic Acids & Related Components Inhibitor

Key Routes of Administration (Marketed) ·       Injection

·       Oral

·       Topical

Key Molecule Types (Marketed) ·       Biologic

·       Small molecules

The Diffuse Large B-Cell Lymphoma (DLBCL) marketed and pipeline drugs market research report includes an assessment of the disease epidemiology, leading marketed products with sales forecast, pricing and reimbursement, and late-to-mid-stage pipeline products with Phase transition success rate (PTSR) and the likelihood of approval (LoA) for Diffuse Large B-Cell Lymphoma (DLBCL). The report also analyzes the clinical and commercial landscapes of DLBCL, as well as an assessment of deals, future market catalysts, key market players, and the future competitive environment.

Key Mechanisms of Action (Pipeline) ·       Cytotoxic

·       Biological Factor Inhibitor

·       Enzyme Inhibitor

·       Receptor Inhibitor

·       Receptor Agonist

Key Routes of Administration (Pipeline) ·       Injection

·       Oral

·       Suppository

·       Topical

Key Molecule Types (Pipeline) ·       Biologic

·       Small molecules

·       Oligonucleotides

Top Sponsors (Marketed and Pipeline Drugs) ·       National Cancer Institute US

·       F. Hoffmann-La Roche Ltd

·       Beigene Ltd

·       Novartis AG

·       Abbvie Inc

·       Celgene Corp

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DLBCL Marketed Drugs Segmentation by Mechanisms of Action

Cytotoxic, receptor agonist, receptor antagonist, protein and peptide inhibitor, and genes, nucleic acids & related components inhibitor are the key MoA in the DLBCL marketed drugs market. Most marketed drugs for DLBCL are cytotoxic, targeting proteins such as CD19 or CD20.

DLBCL Marketed Drugs Analysis by Mechanisms of Action, 2023 (%)

DLBCL Marketed Drugs Analysis by Mechanisms of Action, 2023 (%)

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DLBCL Marketed Drugs Segmentation by Routes of Administration

The key routes of administration for DLBCL marketed drugs are injection, oral, suppository, and topical. In 2023, most of the marketed drugs available for DLBCL are given by injection.

DLBCL Marketed Drugs Analysis by Routes of Administration, 2023 (%)

DLBCL Marketed Drugs Analysis by Routes of Administration, 2023 (%)

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DLBCL Marketed Drugs Segmentation by Molecule Types

The key molecule types for DLBCL marketed drugs are biologic and small molecules. Biologic is leading in the market.

DLBCL Marketed Drugs Analysis by Molecule Types, 2023 (%)

DLBCL Marketed Drugs Analysis by Molecule Types, 2023 (%)

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DLBCL Pipeline Drugs Market Segmentation by Mechanisms of Action

The key mechanisms of action for DLBCL pipeline drugs are cytotoxic, biological factor inhibitor, enzyme inhibitor, receptor inhibitor, and receptor agonist among others. In 2023, most of the drugs in the DLBCL pipeline are cytotoxic.

DLBCL Pipeline Drugs Market Analysis by Mechanisms of Action, 2023 (%)

DLBCL Pipeline Drugs Market Analysis by Mechanisms of Action, 2023 (%)

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DLBCL Pipeline Drugs Market Segmentation by Routes of Administration

The key routes of administration for DLBCL pipeline drugs are injection, oral, and topical. Most pipeline drugs for DLBCL are injection therapies.

DLBCL Pipeline Drugs Market Analysis by Routes of Administration, 2023 (%)

DLBCL Pipeline Drugs Market Analysis by Routes of Administration, 2023 (%)

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DLBCL Pipeline Drugs Market Segmentation by Molecule Types

Most pipeline drugs for DLBCL are biologic, followed by small molecules. Oligonucleotide molecules in development are fewer in number and in earlier stages of development.

DLBCL Pipeline Drugs Market Analysis by Molecule Types, 2023 (%)

DLBCL Pipeline Drugs Market Analysis by Molecule Types, 2023 (%)

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DLBCL Marketed and Pipeline Drugs Market – Competitive Landscape

Some of the top sponsors in the DLBCL marketed and pipeline drugs market are the National Cancer Institute US, F. Hoffmann-La Roche Ltd, Beigene Ltd, Novartis AG, Abbvie Inc, and Celgene Corp, among others. In 2023, the National Cancer Institute US leads among the trial sponsors after adding up all the trial phases.

DLBCL Marketed and Pipeline Drugs Market Analysis by Sponsors, 2023 (%)

DLBCL Marketed and Pipeline Drugs Market Analysis by Sponsors, 2023 (%)

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Segments Covered in the Report

DLBCL Marketed Drugs Mechanism of Action (Number of Drugs, 2023)

  • Cytotoxic
  • Receptor Agonist
  • Receptor Antagonist
  • Protein and Peptide Inhibitor
  • Genes, Nucleic Acids & Related Components Inhibitor

DLBCL Marketed Drugs Routes of Administration Outlook (Number of Drugs, 2023)

  • Injection
  • Oral
  • Topical

DLBCL Marketed Drugs Molecule Types Outlook (Number of Drugs, 2023)

  • Biologics
  • Small molecules

DLBCL Pipeline Drugs Mechanisms of Action Outlook (Number of Drugs, 2023)

  • Cytotoxic
  • Biological Factor Inhibitor
  • Enzyme Inhibitor
  • Receptor Inhibitor
  • Receptor Agonist

DLBCL Pipeline Drugs Routes of Administration Outlook (Number of Drugs, 2023)

  • Injection
  • Oral
  • Suppository
  • Topical

DLBCL Pipeline Drugs Molecule Types Outlook (Number of Drugs, 2023)

  • Biologics
  • Small molecules
  • Oligonucleotides

Scope

Components of the report include –

  • Disease Landscape
  • Disease Overview
  • Epidemiology Overview
  • Treatment Overview
  • Marketed Products Assessment
  • Breakdown by Mechanism of Action, Route of Administration
  • Product Profiles with Sales Forecast
  • Pricing and Reimbursement Assessment
  • Annual Therapy Cost
  • Time to Pricing and Time to Reimbursement
  • Pipeline Assessment
  • Breakdown by Development Stage, Mechanism of Action, Molecule Type, Route of Administration
  • Product Profiles with Sales Forecast
  • Late-to-mid-stage Pipeline Drugs
  • Phase Transition Success Rate and Likelihood of Approval
  • Clinical Trials Assessment
  • Breakdown of Trials by Phase, Status, Virtual Components, Sponsors, Geography, and Endpoint Status
  • Enrolment Analytics, Site Analytics, Feasibility Analysis
  • Deals Landscape
  • Mergers, Acquisitions, and Strategic Alliances by Region
  • Overview of Recent Deals
  • Commercial Assessment
  • Key Market Players
  • Future Market Catalysts

Reasons to Buy

  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the DLBCL market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global DLBCL market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counterstrategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and strategic partnerships.

Table of Contents

1 Preface_x000D_

1.1 Contents_x000D_

1.2 Report Scope_x000D_

1.3 List of Tables and Figures_x000D_

1.4 Abbreviations_x000D_

2 Key Findings_x000D_

3 Disease Landscape_x000D_

3.1 Disease Overview_x000D_

3.2 Epidemiology Overview_x000D_

3.3 Treatment Overview _x000D_

4 Marketed Drugs Assessment_x000D_

4.1 Leading Marketed Drugs_x000D_

4.2 Overview by Mechanism of Action_x000D_

4.3 Overview by Route of Administration_x000D_

4.4 Marketed Drugs Profiles and Sales Forecasts_x000D_

5 Pricing and Reimbursement Assessment_x000D_

5.1 Annual Therapy Cost_x000D_

5.2 Time to Pricing and Reimbursement_x000D_

6 Pipeline Drugs Assessment_x000D_

6.1 Phase III Pipeline Drugs_x000D_

6.2 Overview by Development Stage_x000D_

6.3 Overview by Molecule Type_x000D_

6.4 Overview by Mechanism of Action_x000D_

6.5 Overview by Route of Administration_x000D_

6.6 Drug Specific Phase Transition Success Rate (PTSR) and Likelihood of Approval (LoA)_x000D_

6.7 Therapy Area and Indication-specific PTSR and LoA_x000D_

7 Clinical Trials Assessment_x000D_

7.1 Historical Overview_x000D_

7.2 Overview by Phase_x000D_

7.3 Overview by Status_x000D_

7.4 Overview by Phase for Ongoing and Planned Trials_x000D_

7.5 Trials with Virtual Components_x000D_

7.6 Geographic Overview_x000D_

7.7 Single-Country and Multinational Trials by Region_x000D_

7.8 Top 20 Sponsors with Breakdown by Phase_x000D_

7.9 Top 20 Sponsors with Breakdown by Status_x000D_

7.10 Overview by Endpoint Status_x000D_

7.11 Overview by Race and Ethnicity_x000D_

7.12 Enrollment Data_x000D_

7.13 Top 20 countries for Trial Sites_x000D_

7.14 Top 20 Sites Globally_x000D_

7.15 Feasibility Analysis – Geographic Overview_x000D_

7.16 Feasibility Analysis – Benchmark Models_x000D_

8 Deals Landscape_x000D_

8.1 Mergers, Acquisitions, and Strategic Alliances by Region_x000D_

8.2 Recent Mergers, Acquisitions, and Strategic Alliances_x000D_

9 Commercial Assessment_x000D_

9.1 Key Market Players_x000D_

10 Future Market Catalysts_x000D_

11 Appendix_x000D_

11.1 Methodology_x000D_

11.2 Methodology – Sales Forecast_x000D_

11.3 Methodology – Pricing and Reimbursement_x000D_

11.4 Methodology – PTSR and LoA Analysis_x000D_

11.5 About the Authors_x000D_

11.6 Contact Us_x000D_

11.7 Disclaimer

Frequently asked questions

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