Dilated Cardiomyopathy Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

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Dilated cardiomyopathy (DCM) is a condition in which the heart’s ability to pump blood is decreased because the heart’s main pumping chamber, the left ventricle, is enlarged and weakened. Symptoms include fatigue and weakness, Shortness of breath (dyspnea), lightheadedness, dizziness or fainting, persistent cough or wheezing, lack of appetite, sudden weight gain from fluid retention, and swelling (edema) in the legs, ankles, and feet. Risk factors include family history, alcoholism, hypertension, cocaine abuse, and metabolic disorders, such as thyroid disease or diabetes.

The dilated cardiomyopathy – drugs in development report provides an overview of the dilated cardiomyopathy pipeline landscape. It provides comprehensive information on the therapeutics under development for dilated cardiomyopathy, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history, and the latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Dilated cardiomyopathy and features dormant and discontinued projects.

What are the key targets in the dilated cardiomyopathy pipeline products market?

The key targets in the dilated cardiomyopathy pipeline products market are BAG Family Molecular Chaperone Regulator 3, High Mobility Group Protein B1, Histone Deacetylase 6, Mitogen Activated Protein Kinase 14, Myosin, Prostacyclin Receptor, and Protein S100 A8.

Dilated Cardiomyopathy Pipeline Products by Targets

Dilated Cardiomyopathy Pipeline Products by Targets

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What are the key mechanisms of action in the dilated cardiomyopathy pipeline products market?

The key mechanisms of action in the dilated cardiomyopathy pipeline products market are BAG Family Molecular Chaperone Regulator 3 Activator, High Mobility Group Protein B1 Activator, Histone Deacetylase 6 Inhibitor, Mitogen Activated Protein Kinase 14 Inhibitor, Myosin Activator, Prostacyclin Receptor Agonist, and Protein S100 A8 Activator.

Dilated Cardiomyopathy Pipeline Products by Mechanism of Action

Dilated Cardiomyopathy Pipeline Products by Mechanism of Action

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What are the key routes of administration in the dilated cardiomyopathy pipeline products market?

The key routes of administration in the dilated cardiomyopathy pipeline products market are intravenous, oral, intracoronary, intracardiac, intrapericardial, intravenous bolus, parenteral, and topical.

Dilated Cardiomyopathy Pipeline Products by Routes of Administration

Dilated Cardiomyopathy Pipeline Products by Routes of Administration

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What are the different molecule types in the dilated cardiomyopathy pipeline products market?

The different molecule types in the dilated cardiomyopathy pipeline products market are gene therapy, cell therapy, small molecule, antisense oligonucleotide, aptamer, and peptide.

Dilated Cardiomyopathy Pipeline Products by Molecule Type

Dilated Cardiomyopathy Pipeline Products by Molecule Type

To know more about molecule types, download a free report sample

Which are the major companies in the dilated cardiomyopathy pipeline products market?

The major companies in the dilated cardiomyopathy pipeline products market are DiNAQOR AG, Renovacor Inc, Bristol-Myers Squibb Co, Tenaya Therapeutics Inc, Avery Therapeutics Inc, Berlin Cures Holding AG, BioMarin Pharmaceutical Inc, BridgeBio Pharma Inc, Cardior Pharmaceuticals GmbH, and Celixir Ltd.

Dilated Cardiomyopathy Pipeline Products by Companies

Dilated Cardiomyopathy Pipeline Products by Companies

To know more about major companies, download a free report sample

Market Report Scope

Key targets BAG Family Molecular Chaperone Regulator 3, High Mobility Group Protein B1, Histone Deacetylase 6, Mitogen Activated Protein Kinase 14, Myosin, Prostacyclin Receptor, and Protein S100 A8
Key mechanism of action BAG Family Molecular Chaperone Regulator 3 Activator, High Mobility Group Protein B1 Activator, Histone Deacetylase 6 Inhibitor, Mitogen Activated Protein Kinase 14 Inhibitor, Myosin Activator, Prostacyclin Receptor Agonist, and Protein S100 A8 Activator
Key routes of administration Intravenous, Oral, Intracoronary, Intracardiac, Intrapericardial, Intravenous Bolus, Parenteral, and Topical
Molecule type Gene Therapy, Cell Therapy, and Small Molecule, Antisense Oligonucleotide, Aptamer, and Peptide
Major companies DiNAQOR AG, Renovacor Inc, Bristol-Myers Squibb Co, Tenaya Therapeutics Inc, Avery Therapeutics Inc, Berlin Cures Holding AG, BioMarin Pharmaceutical Inc, BridgeBio Pharma Inc, Cardior Pharmaceuticals GmbH, and Celixir Ltd

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of dilated cardiomyopathy (cardiovascular).
  • The pipeline guide reviews pipeline therapeutics for dilated cardiomyopathy (cardiovascular) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in dilated cardiomyopathy (cardiovascular) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates dilated cardiomyopathy (cardiovascular) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA), and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews the latest news related to pipeline therapeutics for dilated cardiomyopathy (cardiovascular).

Reasons to Buy

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with a potentially strong product portfolio and create effective counter-strategies to gain a competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for dilated cardiomyopathy (cardiovascular).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and their most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding dilated cardiomyopathy (cardiovascular) pipeline depth and focus of indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understanding from the know-how what drove them from the pipeline.

Avery Therapeutics Inc
Berlin Cures Holding AG
BioMarin Pharmaceutical Inc
BridgeBio Pharma Inc
Bristol-Myers Squibb Co
Cardior Pharmaceuticals GmbH
Celixir Ltd
CellServe GmbH
DiNAQOR AG
Dynomics Inc
Heartseed Inc
Help Therapeutics
iHeart Japan Corp
Martin Pharmaceuticals Inc
Maze Therapeutics Inc
NeoProgen Inc
Nuevocor Pte Ltd
Olagenesis Corp
Pfizer Inc
Recursion Pharmaceuticals Inc
Renovacor Inc
Shionogi & Co Ltd
Tenaya Therapeutics Inc

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Dilated Cardiomyopathy – Overview

Dilated Cardiomyopathy – Therapeutics Development

Pipeline Overview

Pipeline by Companies

Pipeline by Universities/Institutes

Products under Development by Companies

Products under Development by Universities/Institutes

Dilated Cardiomyopathy – Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Dilated Cardiomyopathy – Companies Involved in Therapeutics Development

Avery Therapeutics Inc

Berlin Cures Holding AG

BioMarin Pharmaceutical Inc

BridgeBio Pharma Inc

Bristol-Myers Squibb Co

Cardior Pharmaceuticals GmbH

Celixir Ltd

CellServe GmbH

DiNAQOR AG

Dynomics Inc

Heartseed Inc

Help Therapeutics

iHeart Japan Corp

Martin Pharmaceuticals Inc

Maze Therapeutics Inc

NeoProgen Inc

Nuevocor Pte Ltd

Olagenesis Corp

Pfizer Inc

Recursion Pharmaceuticals Inc

Renovacor Inc

Shionogi & Co Ltd

Tenaya Therapeutics Inc

Dilated Cardiomyopathy – Drug Profiles

BC-007 – Drug Profile

Product Description

Mechanism Of Action

History of Events

CDR-426D – Drug Profile

Product Description

Mechanism Of Action

Cell Therapy for Dilated Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

danicamtiv – Drug Profile

Product Description

Mechanism Of Action

History of Events

DINA-005 – Drug Profile

Product Description

Mechanism Of Action

DINA-006 – Drug Profile

Product Description

Mechanism Of Action

DINA-008 – Drug Profile

Product Description

Mechanism Of Action

DINA-009 – Drug Profile

Product Description

Mechanism Of Action

DINA-010 – Drug Profile

Product Description

Mechanism Of Action

DINA-011 – Drug Profile

Product Description

Mechanism Of Action

DYN-101 – Drug Profile

Product Description

Mechanism Of Action

emprumapimod – Drug Profile

Product Description

Mechanism Of Action

History of Events

Gene Therapy for Dilated Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

Gene Therapy for Dilated Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

Gene Therapy for Dilated Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

History of Events

Gene Therapy for Dilated Cardiomyopathy and Heart Failure – Drug Profile

Product Description

Mechanism Of Action

Gene Therapy to Activate BAG3 for Dilated Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

Heartcel – Drug Profile

Product Description

Mechanism Of Action

History of Events

HS-001 – Drug Profile

Product Description

Mechanism Of Action

History of Events

IHJ-301 – Drug Profile

Product Description

Mechanism Of Action

MyCardia – Drug Profile

Product Description

Mechanism Of Action

Neo-2001 – Drug Profile

Product Description

Mechanism Of Action

NovoCardia – Drug Profile

Product Description

Mechanism Of Action

redasemtide trifluoroacetate – Drug Profile

Product Description

Mechanism Of Action

REN-001 – Drug Profile

Product Description

Mechanism Of Action

History of Events

Small Molecule for Dilated Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

Small Molecules for Dilated Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

Small Molecules for Dilated Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

History of Events

Stem Cell Therapy for Myocardial Infarction and Dilated Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

History of Events

TN-301 – Drug Profile

Product Description

Mechanism Of Action

History of Events

trimetazidine – Drug Profile

Product Description

Mechanism Of Action

History of Events

YS-1402 – Drug Profile

Product Description

Mechanism Of Action

Dilated Cardiomyopathy – Dormant Projects

Dilated Cardiomyopathy – Product Development Milestones

Featured News & Press Releases

Jul 13, 2021: Tenaya Therapeutics unveils preclinical research supporting product candidate for rare and prevalent heart disease indications at ESC Heart Failure 2021

Sep 09, 2020: MyoKardia doses first patient in phase 2 clinical trial of danicamtiv in genetic dilated cardiomyopathy

Mar 26, 2020: MyoKardia Provides clinical trial update on Danicamtiv study

Oct 28, 2019: MyoKardia Announces Positive MYK-491 Data; Advancing Program into Targeted Genetic Dilated Cardiomyopathy Population

May 30, 2019: MyoKardia’s MYK-491 shows favourable profile in Phase Ia study

Apr 15, 2019: Berlin Cures announces start of Phase IIa for its DNA-based neutralizer of ß1-adrenoceptor autoantibodies

Dec 11, 2018: MyoKardia reports positive data from phase 1b single-ascending dose clinical trial of MYK-491 in dilated cardiomyopathy and systolic heart failure patients

Dec 06, 2018: Berlin Cures steering committee is assembled to facilitate the design and implementation of phase 2 study of BC 007

Oct 30, 2018: MyoKardia Shares Data from new research program ACT-1 at 2018 R&D Day

Feb 26, 2018: Heart Failure Treatment from Berlin Cures Shows Promise in Phase 1 Study

Feb 14, 2018: MyoKardia Begins Patient Dosing in Phase 1b Clinical Study of MYK-491 in Dilated Cardiomyopathy Patients

Nov 02, 2017: MyoKardia Provides Update on MYK-491

Sep 27, 2017: MyoKardia Provides Update on MYK-491 Clinical Progress

Feb 02, 2017: First Subjects Dosed in MyoKardia Phase 1 Study of Dilated Cardiomyopathy Candidate MYK-491

Dec 02, 2016: MyoKardia Announces Receipt of Milestone Payment from Sanofi for DCM Candidate MYK-491

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Products under Development for Dilated Cardiomyopathy, 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Universities/Institutes, 2022

Products under Development by Companies, 2022

Products under Development by Companies, 2022 (Contd..1)

Products under Development by Universities/Institutes, 2022

Number of Products by Stage and Target, 2022

Number of Products by Stage and Mechanism of Action, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Dilated Cardiomyopathy – Pipeline by Avery Therapeutics Inc, 2022

Dilated Cardiomyopathy – Pipeline by Berlin Cures Holding AG, 2022

Dilated Cardiomyopathy – Pipeline by BioMarin Pharmaceutical Inc, 2022

Dilated Cardiomyopathy – Pipeline by BridgeBio Pharma Inc, 2022

Dilated Cardiomyopathy – Pipeline by Bristol-Myers Squibb Co, 2022

Dilated Cardiomyopathy – Pipeline by Cardior Pharmaceuticals GmbH, 2022

Dilated Cardiomyopathy – Pipeline by Celixir Ltd, 2022

Dilated Cardiomyopathy – Pipeline by CellServe GmbH, 2022

Dilated Cardiomyopathy – Pipeline by DiNAQOR AG, 2022

Dilated Cardiomyopathy – Pipeline by Dynomics Inc, 2022

Dilated Cardiomyopathy – Pipeline by Heartseed Inc, 2022

Dilated Cardiomyopathy – Pipeline by Help Therapeutics, 2022

Dilated Cardiomyopathy – Pipeline by iHeart Japan Corp, 2022

Dilated Cardiomyopathy – Pipeline by Martin Pharmaceuticals Inc, 2022

Dilated Cardiomyopathy – Pipeline by Maze Therapeutics Inc, 2022

Dilated Cardiomyopathy – Pipeline by NeoProgen Inc, 2022

Dilated Cardiomyopathy – Pipeline by Nuevocor Pte Ltd, 2022

Dilated Cardiomyopathy – Pipeline by Olagenesis Corp, 2022

Dilated Cardiomyopathy – Pipeline by Pfizer Inc, 2022

Dilated Cardiomyopathy – Pipeline by Recursion Pharmaceuticals Inc, 2022

Dilated Cardiomyopathy – Pipeline by Renovacor Inc, 2022

Dilated Cardiomyopathy – Pipeline by Shionogi & Co Ltd, 2022

Dilated Cardiomyopathy – Pipeline by Tenaya Therapeutics Inc, 2022

Dilated Cardiomyopathy – Dormant Projects, 2022

Figures

List of Figures

Number of Products under Development for Dilated Cardiomyopathy, 2022

Number of Products under Development by Companies, 2022

Number of Products by Targets, 2022

Number of Products by Stage and Targets, 2022

Number of Products by Mechanism of Actions, 2022

Number of Products by Stage and Mechanism of Actions, 2022

Number of Products by Routes of Administration, 2022

Number of Products by Stage and Routes of Administration, 2022

Number of Products by Molecule Types, 2022

Number of Products by Stage and Molecule Types, 2022

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