Major depressive disorder (MDD) is one of the most common psychiatric diseases worldwide. The MDD market is a crowded and competitive market, with more than 30 marketed products available for the treatment of patients with MDD. The depression market is about to enter a dynamic phase with imminent patent expiries for top selling products, such as Eli Lilly’s Cymbalta, and Otsuka/BMS’s Abilify, along with the recent launch of the multimodal antidepressant, Lundbeck/Takeda’s Brintellix, in January 2014, and the potential introduction of seven promising late-stage pipeline products into the market during the forecast period, from 2013 to 2023. Effexor (venlafaxine) is an antidepressant that belongs to the SNRI class. It was developed and launched by Wyeth, which was later fully acquired by Pfizer. Effexor first became available in the US and 5EU in 1994, and its extended release formulation (Effexor XR) was introduced into the US and 5EU markets in 1998.
Overview of Major depressive disorder, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
Detailed information on Effexor including product description, safety and efficacy profiles as well as a SWOT analysis.
Sales forecast for Effexor for the top seven countries from 2013 to 2023.
Sales information covered for the US, France, Germany, Italy, Spain, the UK and Australia.
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Obtain sales forecast for Effexor from 2013-2023 in the top seven countries (the US, France, Germany, Italy, Spain, the UK and Australia)
Table of Contents
1Table of Contents1
1.1List of Tables3
1.2List of Figures4
2.1Sales for Effexor in the Major Depressive Disorder (MDD) Market5
2.2What Do the Physicians Think?6
3.3Upcoming Related Reports10
4.1Etiology and Pathophysiology11
4.3Symptoms and Subtypes of Major Depressive Disorder15
4.5Quality of Life16
5.1Diagnosis and Treatment Overview16
5.1.2Treatment Guidelines and Leading Prescribed Drugs18
8.4.1Diagnosed MDD Patients37
8.4.2Percent of Drug-Treated Patients37
8.4.3General Pricing Assumptions38
8.4.4Individual Drug Assumptions38
8.5Physicians and Specialists Included in this Study40
8.6About the Authors42
8.6.2Therapy Area Directors42
8.6.3Global Head of Healthcare43
List of Tables
Table 1: Effexor: Key Metrics in the 7MM and Australia Major Depressive Disorder Markets, 2013–20234
Table 2: Classification and Criteria of Major Depressive Disorder (DSM-IV) and Major Depressive Episode (ICD-10)14
Table 3: Subtypes of Major Depressive Disorder15
Table 4: Severity of Depressive Episodes according to ICD-10 and DSM-IV Diagnostic Criteria17
Table 5: Treatment Guidelines for Major Depressive Disorder19
Table 6: Most Prescribed Drugs for MDD by Class in the 7MM and Australia, 201321
Table 7: Leading Treatments for MDD, 201327
Table 8: Product Profile – Effexor29
Table 9: Effexor SWOT Analysis, 201431
Table 10:Global MDD Sales Forecasts ($m) for Effexor XR, 2013–202332
Table 11:High-Prescribing Physicians (Non-KOLs) Surveyed, by Country41
List of Figures
Figure 1: Sales for Effexor by Region, 2013-20236
Figure 2: Overview of Targets of Antidepressant Action on Noradrenergic and Serotonergic Neurons13
Figure 3: Disease Management Model for Major Depressive Disorder23
Figure 4: Major Depressive Disorder Treatment Algorithm25
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