EpiCast Report: Diabetic Foot Ulcers – Epidemiology Forecast to 2025

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Diabetic foot ulcers (DFUs) are a common and disabling condition among people with diabetes. Globally, the prevalence of DFU among people with diabetes varies widely, ranging from 5.1% in the UK to approximately 11.9% in Algeria. The lifetime risk of developing a DFU in an individual with diabetes is approximately 25%. DFUs have become an increasingly significant public health concern in both the developed and the developing world, and are a major cause of hospitalizations and the leading cause of lower-extremity amputations in diabetics. Given the increasing prevalence of diabetes coupled with the aging population, the burden of complications related to diabetes such as DFUs is likely to increase over the next 20 years.

GlobalData epidemiologists forecast that the diagnosed incident cases of DFU among the diagnosed diabetic population in the 7 MM will increase from 1,060,036 cases in 2015 to 1,487,754 cases in 2025, at an Annual Growth Rate (AGR) of 4.03%. In the 7MM, GlobalData epidemiologists forecast that the total prevalent cases of DFUs among the diagnosed diabetic population will increase from 4,975,656 cases in 2015 to 7,063,884 cases in 2025, at an AGR of 4.20%.

GlobalData epidemiologists forecast the diagnosed incident cases and total prevalent cases of DFU in the 7MM from 2015-2025 using studies published in peer-reviewed journals that provided age- and sex-specific diagnosed incidence and total prevalence of DFU in the respective markets. GlobalData epidemiologists further segmented the diagnosed incident cases of DFU by classification of DFUs (neuropathic, ischemic, and neuroischemic). Additionally, the report includes a forecast of the cases of diabetic foot infection and peripheral artery disease (PAD) among the diagnosed incident population of DFUs in the 7MM. GlobalData epidemiologists ensured that the forecast methodology was consistent across all the 7MM to allow for a meaningful comparison of the forecast numbers across these markets.

Scope

The Diabetic Foot Ulcers (DFU) EpiCast Report and EpiCast Model provide an overview of the risk factors and global trends of DFU in the seven major markets (7MM) (US, France, Germany, Italy, Spain, UK, and Japan). It includes a 10-year epidemiological forecast for the diagnosed incident cases of DFU and total prevalent cases of DFU (diagnosed and undiagnosed cases), which are segmented by sex and age. The diagnosed incident cases of DFU are further segmented by classification of DFUs (neuropathic, ischemic, and neuroischemic). Additionally, the report includes a forecast of the cases of diabetic foot infection and peripheral artery disease (PAD) among the diagnosed incident population of DFUs in the 7MM.

The DFU epidemiology report and model were written and developed by Masters- and PhD-level epidemiologists.

The EpiCast Report is in-depth, high quality, transparent and market-driven, providing expert analysis of disease trends in the 7MM.

The EpiCast Model is easy to navigate, interactive with dashboards, and epidemiology-based with transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over a 10-year forecast period using reputable sources.

Table of Contents

1Table of Contents

1.1List of Tables

1.2List of Figures

2Epidemiology

2.1Disease Background

2.2Risk Factors and Comorbidities

2.3Global Trends

2.3.1Diagnosed Incidence and Total Prevalence

2.4Forecast Methodology

2.4.1Sources Used Tables

2.4.2Forecast Assumptions and Methods

2.4.3Sources Not Used

2.5Epidemiological Forecast of DFU (2015–2025)

2.5.1Diagnosed Incident Cases of DFU Among the Diagnosed Diabetic Population

2.5.2Total Prevalent Cases of DFU Among the Diagnosed Diabetic Population

2.6Discussion

2.6.1Epidemiological Forecast Insight

2.6.2Limitations of the Analysis

2.6.3Strengths of the Analysis

3Appendix

3.1Bibliography

3.2About the Authors

3.2.1Epidemiologists

3.2.2Reviewers

3.2.3Global Director of Therapy Analysis and Epidemiology

3.3About GlobalData

3.4About EpiCast

3.5Contact Us

3.6Disclaimer

Table

Table 1: Risk Factors and Comorbidities of DFUs

Table 2: 7MM, Diagnosed Incidence of DFU Among the Diabetic Population from 1993–2008

Table 3: 7MM, Total Prevalence of DFU Among the Diabetic Population from 1990–2008

Table 4: 7MM, Sources Used to Forecast the Diagnosed Incident Cases of DFU Among the Diagnosed Diabetic Population

Table 5: 7MM, Sources Used for the Classification of DFUs Among the DFU-Diagnosed Incident Population

Table 6: 7MM, Sources Used to Forecast Diabetic Foot Infection and PAD Cases Among the DFU-Diagnosed Incident Population

Table 7: 7MM, Sources Used to Forecast the Total Prevalent Cases of DFU Among the Diagnosed Diabetic Population

Table 8: 7MM, Sources Not Used in Epidemiological Analysis of DFU

Table 9: 7MM, Diagnosed Incident Cases of DFU, Ages =20 Years, Both Sexes, N, Selected Years 2015–2025

Table 10. 7MM, Diagnosed Incident Cases of DFU, by Age, Both Sexes, N (Row %), 2015

Table 11: 7MM, Diagnosed Incident Cases of DFU, by Sex, Ages =20 Years, N (Row %), 2015

Table 12: 7MM, Total Prevalent Cases of DFU, Ages =20 Years, Both Sexes, N, Selected Years 2015–2025

Table 13. 7MM, Total Prevalent Cases of DFU, by Age, Both Sexes, N (Row %), 2015

Table 14: 7MM, Total Prevalent Cases of DFU, by Sex, Ages =20 Years, N (Row %), 2015

Figures

Figure 1: 7MM, Diagnosed Incident Cases of DFU, Ages =20 Years, Both Sexes, N, Selected Years 2015–2025

Figure 2: 7MM, Diagnosed Incident Cases of DFU, by Age, Both Sexes, N, 2015

Figure 3: 7MM, Diagnosed Incident Cases of DFU, Ages =20 Years, by Sex, N , 2015

Figure 4: 7MM, Age-Standardized Diagnosed Incidence of DFU, Ages =20 Years, by Sex, Cases per 100,000 Diabetic Population, 2015

Figure 5: 7MM, Diagnosed Incident Cases of DFU by Classification, Both Sexes, Ages =20 Years, 2015

Figure 6: 7MM, Diabetic Foot Infection Cases Among the DFU-Diagnosed Incident Population, Both Sexes, Ages =20 Years, 2015

Figure 7: 7MM, PAD Cases Among the DFU-Diagnosed Incident Population, Both Sexes, Ages =20 Years, 2015

Figure 8: 7MM, Total Prevalent Cases of DFU, Ages =20 Years, Both Sexes, N, Selected Years 2015–2025

Figure 9: 7MM, Total Prevalent Cases of DFU, by Age, Both Sexes, N, 2015

Figure 10: 7MM, Total Prevalent Cases of DFU, Ages =20 Years, by Sex, N , 2015

Figure 11: 7MM, Age-Standardized Total Prevalence of DFU, Ages =20 Years, by Sex, %, 2015

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