EpiCast Report: Head and Neck Cancers – Epidemiology Forecast to 2024

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Head and neck cancers (HNCs) are a heterogeneous group, consisting of cancers of the mouth, including the lip, tongue, gum, floor of mouth, palate, and other parts of mouth; the salivary glands; the pharynx, including the tonsil, oropharynx, nasopharynx, pyriform fossa, hypopharynx, other mouth/pharynx; the nose, sinuses, and related structures; the larynx; and the thyroid. HNCs usually begin in the squamous cells that line the moist mucosal surfaces of the tissues and organs of the head and neck — more than 80% of all HNCs are squamous cell carcinomas. HNCs are common in several regions across the globe and account for 600,000 new cases annually worldwide.GlobalData epidemiologists forecast an increase in diagnosed incident cases of HNCs in the 7MM from 151,393 diagnosed incident cases in 2014 to 174,056 diagnosed incident cases in 2024, with an Annual Growth Rate (AGR) of 1.50% during the forecast period. In 2024, the US will have the highest number of diagnosed incident cases of HNCs in the 7MM, with 65,663 diagnosed incident cases, whereas the UK will have the lowest number of diagnosed incident cases of HNCs, with 12,702 diagnosed incident cases in 2024. The diagnosed incident cases of thyroid cancer in the 7MM are expected to increase from 93,225 diagnosed incident cases in 2014 to 123,504 diagnosed incident cases in 2024, with an AGR of 3.25% during the forecast period. In 2024, the US will have the highest number of diagnosed incident cases of thyroid cancer in the 7MM with 81,286 diagnosed incident cases, whereas Spain will have the lowest number of diagnosed incident cases of thyroid cancer with 3,233 diagnosed incident cases in 2024.

Scope

The Head and neck cancers (HNCs) EpiCast Report and EpiCast Model provide an overview of the risk factors, comorbidities, and the global and historical trends for HNCs in the seven major markets (7MM) (US, France, Germany, Italy, Spain, UK, and Japan). It includes a 10-year epidemiological forecast of the diagnosed incident cases of HNCs segmented into three sub-groups: cancers of the lip, oral cavity, and pharynx; cancers of the nose, sinuses, and related structures; and cancers of the larynx, in these markets. It also includes a 10-year epidemiological forecast for the five-year diagnosed prevalent cases of HNCs (excluding nose, sinuses, and related cancers). Additionally, it includes a 10-year epidemiological forecast for the diagnosed incident cases and the five-year diagnosed prevalent cases of thyroid cancer in the 7MM. The diagnosed incident cases of HNCs (excluding nose, sinuses, and related cancers) and thyroid cancer are segmented by age, sex, clinical stage at diagnosis, and histology.

The HNCs epidemiology report and model were written and developed by Masters- and PhD-level epidemiologists.

The EpiCast Report is in-depth, high quality, transparent and market-driven, providing expert analysis of disease trends in the 7MM.

The EpiCast Model is easy to navigate, interactive with dashboards, and epidemiology-based with transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over a 10-year forecast period using reputable sources.

Table of Contents

1Table of Contents

1.1List of Tables

1.2List of Figures

2Introduction

2.1Catalyst

2.2Related Reports

2.3Upcoming Reports

3Epidemiology

3.1Disease Background

3.2Risk Factors and Comorbidities

3.3Global Trends

3.3.1Incidence

3.3.2Relative Survival – 7MM

3.4Forecast Methodology

3.4.1Sources Used

3.4.2Sources Not Used

3.4.3Forecast Assumptions and Methods

3.5Epidemiological Forecast for HNCs and Thyroid Cancer (2014–2024)

3.5.1Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer

3.5.2Diagnosed Incident Cases of Nose, Sinuses, and Related Cancers

3.5.3Diagnosed Incident Cases of Larynx Cancer

3.5.4Diagnosed Incident Cases of HNCs

3.5.5Diagnosed Incident Cases of Thyroid Cancer

3.5.6Age-Specific Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer

3.5.7Age-Specific Diagnosed Incident Cases of Larynx Cancer

3.5.8Age-Specific Diagnosed Incident Cases of Thyroid Cancer

3.5.9Sex-Specific Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer

3.5.10Sex-Specific Diagnosed Incident Cases of Larynx Cancer

3.5.11Sex-Specific Diagnosed Incident Cases of Thyroid Cancer

3.5.12Age-Standardized Diagnosed Incidence of Lip, Oral Cavity, and Pharynx Cancer

3.5.13Age-Standardized Diagnosed Incidence of Larynx Cancer

3.5.14Age-Standardized Diagnosed Incidence of Thyroid Cancer

3.5.15Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer by Clinical Stage at Diagnosis

3.5.16Diagnosed Incident Cases of Larynx Cancer by Clinical Stage at Diagnosis

3.5.17Diagnosed Incident Cases of Thyroid Cancer by Clinical Stage at Diagnosis

3.5.18Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer by Histology Distribution

3.5.19Diagnosed Incident Cases of Nose, Sinuses, and Related Cancers by Histology Distribution

3.5.20Diagnosed Incident Cases of Larynx Cancer by Histology Distribution

3.5.21Diagnosed Incident Cases of Thyroid Cancer by Histology Distribution

3.5.22Five-Year Diagnosed Prevalent Cases of Lip, Oral Cavity, and Pharynx Cancer

3.5.23Five-Year Diagnosed Prevalent Cases of Larynx Cancer

3.5.24Five-Year Diagnosed Prevalent Cases of Thyroid Cancer

3.6Discussion

3.6.1Epidemiological Forecast Insight

3.6.2Limitations of the Analysis

3.6.3Strengths of the Analysis

4Appendix

4.1Bibliography

4.2About the Authors

4.2.1Epidemiologists

4.2.2Reviewers

4.2.3Global Director of Therapy Analysis and Epidemiology

4.2.4Global Head of Healthcare

4.3About GlobalData

4.4About EpiCast

4.5Disclaimer

Table

Table 1: HNCs Clinical Stages at Diagnosis

Table 2: Risk Factors for HNCs

Table 3: Trends in the Age-Adjusted Incidence of Lip, Oral Cavity, and Pharynx Cancer in the 7MM, All Ages, 1998–2007

Table 4: Trends in the Age-Adjusted Incidence of Larynx Cancer in the 7MM, All Ages, 1998–2007

Table 5: Trends in the Age-Adjusted Incidence of Thyroid Cancer in the 7MM, All Ages, 1998–2007

Table 6: Trends in the Five-Year Relative Survival (%) of HNCs and Thyroid Cancer in the 7MM, Both Sexes, 1993–2007

Table 7: 7MM, Sources of Epidemiological Data Used for the Forecast for the Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer

Table 8: 7MM, Sources of Epidemiological Data Used for the Forecast for the Diagnosed Incident Cases of Larynx Cancer

Table 9: 7MM, Sources of Epidemiological Data Used for the Forecast for the Diagnosed Incident Cases of Nose, Sinuses, and Related Cancer

Table 10: 7MM, Sources of Epidemiological Data Used for the Forecast for the Diagnosed Incident Cases of Thyroid Cancer

Table 11: 7MM, Sources of Epidemiological Data Used for the Forecast for the Five-Year Diagnosed Prevalent Cases of Lip, Oral Cavity, and Pharynx Cancer

Table 12: 7MM, Sources of Epidemiological Data Used for the Forecast for the Five-Year Diagnosed Prevalent Cases of Larynx Cancer

Table 13: 7MM, Sources of Epidemiological Data Used for the Forecast for the Five-Year Diagnosed Prevalent Cases of Thyroid Cancer

Table 14: 7MM, Sources of Epidemiological Data Used for the Segmentation of Diagnosed Incident Cases of HNCs (Excluding Nose, Sinuses, and Related Cancers) and Thyroid Cancer by Clinical Stage at Diagnosis

Table 15: 7MM, Sources of Epidemiological Data Used for the Segmentation of the Diagnosed Incident Cases HNCs and Thyroid Cancer by Histology Distribution

Table 16: 7MM, Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer, Both Sexes, All Ages, N, 2014–2024

Table 17: 7MM, Diagnosed Incident Cases of Nose, Sinuses, and Related Cancer, Both Sexes, All Ages, N, 2014–2024

Table 18: 7MM, Diagnosed Incident Cases of Larynx Cancer, Both Sexes, All Ages, N, 2014–2024

Table 19: 7MM, Diagnosed Incident Cases of HNCs, Both Sexes, All Ages, N, 2014–2024

Table 20: 7MM, Diagnosed Incident Cases of Thyroid Cancer, Both Sexes, All Ages, N, 2014–2024

Table 21: 7MM, Age-Specific Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer, Both Sexes, N (Row %), 2014

Table 22: 7MM, Age-Specific Diagnosed Incident Cases of Larynx Cancer, Both Sexes, N (Row %), 2014

Table 23: 7MM, Age-Specific Diagnosed Incident Cases of Thyroid Cancer, Both Sexes, N (Row %), 2014

Table 24: 7MM, Sex-Specific Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer, All Ages, N (Row %), 2014

Table 25: 7MM, Sex-Specific Diagnosed Incident Cases of Larynx Cancer, All Ages, N (Row %), 2014

Table 26: 7MM, Sex-Specific Diagnosed Incident Cases of Thyroid Cancer, All Ages, N (Row %), 2014

Table 27: 7MM, Five-Year Diagnosed Prevalent Cases of Lip, Oral Cavity, and Pharynx Cancer, All Ages, Both Sexes, N, 2014–2024

Table 28: 7MM, Five-Year Diagnosed Prevalent Cases of Larynx Cancer, All Ages, Both Sexes, N, 2014–2024

Table 29: 7MM, Five-Year Diagnosed Prevalent Cases of Thyroid Cancer, All Ages, Both Sexes, N, 2014–2024

Figures

Figure 1: 7MM, Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer, Both Sexes, All Ages, N, 2014–2024

Figure 2: 7MM, Diagnosed Incident Cases of Nose, Sinuses, and Related Cancer, Both Sexes, All Ages, N, 2014–2024

Figure 3: 7MM, Diagnosed Incident Cases of Larynx Cancer, Both Sexes, All Ages, N, 2014–2024

Figure 4: 7MM, Diagnosed Incident Cases of HNCs, Both Sexes, All Ages, N, 2014–2024

Figure 5: 7MM, Diagnosed Incident Cases of Thyroid Cancer, Both Sexes, All Ages, N, 2014–2024

Figure 6: 7MM, Age-Specific Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer, Both Sexes, N, 2014

Figure 7: 7MM, Age-Specific Diagnosed Incident Cases of Larynx Cancer, Both Sexes, N, 2014

Figure 8: 7MM, Age-Specific Diagnosed Incident Cases of Thyroid Cancer, Both Sexes, N, 2014

Figure 9: 7MM, Sex-Specific Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer, All Ages, N, 2014

Figure 10: 7MM, Sex-Specific Diagnosed Incident Cases of Larynx Cancer, All Ages, N, 2014

Figure 11: 7MM, Sex-Specific Diagnosed Incident Cases of Thyroid Cancer, All Ages, N, 2014

Figure 12: 7MM, Age-Standardized Diagnosed Incidence Cases of Lip, Oral Cavity, and Pharynx Cancer (Cases per 100,000 Population), All Ages, by Sex, 2014

Figure 13: 7MM, Age-Standardized Diagnosed Incidence Cases of Larynx Cancer (Cases per 100,000 Population), All Ages, by Sex, 2014

Figure 14: 7MM, Age-Standardized Diagnosed Incidence Cases of Thyroid Cancer (Cases per 100,000 Population), All Ages, by Sex, 2014

Figure 15: 7MM, Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer by Clinical Stage at Diagnosis, All Ages, Both Sexes, N, 2014

Figure 16: 7MM, Diagnosed Incident Cases of Larynx Cancer by Clinical Stage at Diagnosis, All Ages, Both Sexes, N, 2014

Figure 17: 7MM, Diagnosed Incident Cases of Thyroid Cancer by Clinical Stage at Diagnosis, All Ages, Both Sexes, N, 2014

Figure 18: 7MM, Diagnosed Incident Cases of Lip, Oral Cavity, and Pharynx Cancer by Histology Distribution, All Ages, Both Sexes, N, 2014

Figure 19: 7MM, Diagnosed Incident Cases of Nose, Sinuses, and Related Cancers by Histology Distribution, All Ages, Both Sexes, N, 2014

Figure 20: 7MM, Diagnosed Incident Cases of Larynx Cancer by Histology Distribution, All Ages, Both Sexes, N, 2014

Figure 21: 7MM, Diagnosed Incident Cases of Thyroid Cancer by Histology Distribution, All Ages, Both Sexes, N, 2014

Figure 22: 7MM, Five-Year Diagnosed Prevalent Cases of Lip, Oral Cavity, and Pharynx Cancer, All Ages, Both Sexes, N, 2014–2024

Figure 23: 7MM, Five-Year Diagnosed Prevalent Cases of Larynx Cancer, All Ages, Both Sexes, N, 2014–2024

Figure 24: 7MM, Five-Year Diagnosed Prevalent Cases of Thyroid Cancer, All Ages, Both Sexes, N, 2014–2024

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