EpiCast Report: Diabetic Foot Ulcers – Epidemiology Forecast To 2022

Diabetic foot ulcers (DFUs) are a major complication of diabetes and the most common foot injury in diabetics. DFUs occur as a result of trauma to or extreme pressure on any part of the foot in diabetics. The lifetime risk of an individual with diabetes developing a DFU is approximately 25%, according to a meta-analysis of studies conducted during 1980–2004. DFUs have become an increasingly significant public health concern in both the developed and the developing world, and are a major cause of hospitalizations, as well the leading cause of lower-extremity amputations, in diabetics.

Globally, the morbidity associated with DFUs varies widely, with the prevalence ranging from 1.4% in the UK to approximately 12% in Algeria (Boulton, 2000; Lavery et al., 2003; Reiber, 2001). Given the increasing prevalence of diabetes, coupled with the aging population, the burden of complications related to diabetes, such as DFUs, is also likely to increase over the next 20 years (Boulton et al., 2005).

GlobalData epidemiologists forecast that the total prevalent cases of DFUs in the six major markets (6MM) (US, France, Germany, Italy, Spain, and UK) will grow from 3,811,190 cases in 2012 to 5,647,926 cases in 2022, at an Annual Growth Rate (AGR) of 4.82%. Approximately 80% of the total prevalent cases of DFUs will be in the US, with the number of cases increasing from 2,842,976 cases in 2012 to 4,328,256 cases in 2022, at an AGR of 5.22%. The increase in the number of total prevalent cases of DFUs in the 6MM is the result of changing population demographics and GlobalData’s predicted increase in the diagnosed prevalent cases of diabetes in the 6MM.

Scope

The diabetic foot ulcers (DFU) EpiCast Report provides an overview of the risk factors and epidemiological trends for DFU in the seven major markets (6MM) (US, France, Germany, Italy, Spain, and UK). It includes a 10-year epidemiological forecast of the total prevalent cases of DFUs in the diagnosed diabetic population segmented by age, (ages 20 to >85 years), sex, and the proportion of diabetic foot infections in these markets. The DFU epidemiology report was written and developed by Masters- and PhD-level epidemiologists. The EpiCast Report is in-depth, high quality, transparent and market-driven, providing expert analysis of disease trends in the 6MM.

Reasons to buy

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Table of Contents

1Table of Contents1

1.1List of Tables2

1.2List of Figures3

2Executive Summary3

3Introduction5

3.1Catalyst5

3.2Related Reports6

3.3Upcoming Reports6

4Epidemiology6

4.1Disease Background6

4.2Risk Factors and Comorbidities7

4.2.1An Increased Duration of Diabetes Triples the Risk of Dfus7

4.2.2Men Diabetics are at Higher Risk for Dfus than Women Diabetics8

4.3Global Trends8

4.3.1US10

4.3.25EU11

4.4Forecast Methodology12

4.4.1Sources Used13

4.4.2Sources Not Used15

4.4.3Forecast Assumptions and Methods, Diagnosed Prevalent Cases of Diabetes16

4.4.4Forecast Assumptions and Methods, Diabetic Foot Ulcers19

4.5Epidemiological Forecast for DFUs (2012–2022)22

4.5.1Total Prevalent Cases of DFUs22

4.5.2Age-Specific Total Prevalent Cases of DFUs24

4.5.3Sex-Specific Total Prevalent Cases of DFUs26

4.5.4Total Prevalent Cases of Diabetic Foot Infections27

4.6Discussion29

4.6.1Epidemiological Forecast Insight29

4.6.2Limitations of the Analysis29

4.6.3Strengths of the Analysis30

5Appendix30

5.1Bibliography30

5.2About the Authors35

5.2.1Epidemiologists35

5.2.2Reviewers35

5.2.3Global Director of Epidemiology and Health Policy36

5.2.4Global Head of Healthcare36

5.3About GlobalData38

5.4About EpiCast38

5.5Contact Us38

5.6Disclaimer39

List of Tables

Table 1: Risk Factors for DFUs7

Table 2: Epidemiological Sources Used to Forecast the Total Prevalence of DFUs and Diabetic Foot Infections in the Diagnosed Diabetic Population12

Table 3: 6MM, Total Prevalent Cases of DFUs, Ages =20 Years, Both Sexes, N, 2012–202222

Table 4: 6MM, Total Prevalent Cases of DFUs, by Age, Both Sexes, N, (Row %), 201224

Table 5: 6MM, Total Prevalent Cases of DFUs, by Sex, Ages =20 years, N (Row %), 201226

Table 6: 6MM, Total Prevalent Cases of Diabetic Foot Infections, Ages =20 years, Both Sexes, N, 2012–202227

List of Figures

Figure 1: 6MM, Total Prevalent Cases of DFUs, Ages = 20 Years, Men and Women, N, 2012 and 20224

Figure 2: 6MM, Total Prevalent Cases of DFUs, Ages =20 Years, Both Sexes, N, 2012–202223

Figure 3: 6MM, Total Prevalent Cases of DFUs, by Age, Both Sexes, N, 201225

Figure 4: 6MM, Total Prevalent Cases of DFUs, by Sex, Ages =20 Years, N, 201227

Figure 5: 6MM, Total Prevalent Cases of Diabetic Foot Infections, Ages =20 Years, Both Sexes, N, 2012–202228

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