EpiCast Report: Colorectal Cancer – Epidemiology Forecast to 2025

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Colorectal cancer (CRC) is a cancer that starts in the colon or the rectum (ACS, 2016). CRC is one of the most common types of cancers diagnosed. For this analysis, GlobalData epidemiologists defined CRC as a cancer in all sub-sites of the colon and rectum, using the International Classification of Diseases, Tenth Revision (ICD-10) codes for CRC (C18-C20). To build the forecast, GlobalData epidemiologists sourced international and national cancer databases such as the Cancer Incidence in Five Continents (CI5) CI5plus data analysis tool; the EUROCARE-5 survival database; Surveillance, Epidemiology and End Results (SEER); the German Centre for Cancer Registry (ZfKD); peer-reviewed research articles; and government publications. The forecast methodology is consistent across each of the eight markets, thereby allowing for a meaningful comparison among them.

In 2015, there were 746,590 diagnosed incident cases of CRC in the 8MM. GlobalData epidemiologists forecast that the diagnosed incident cases in the 8MM will increase to 913,832 by 2025 at an Annual Growth Rate (AGR) of 2.24%. With the exception of the US and Germany, all markets will see an increase in the number of cases, at varying AGRs. The 8MM combined had an estimated 2,582,288 five-year diagnosed prevalent cases of CRC in 2015. The number of five-year diagnosed prevalent cases will increase by 22.06% over the next 10 years to 3,151,930 by 2025. Urban China will have the highest number of diagnosed incident and five-year diagnosed prevalent cases among the 8MM, as well as the highest AGR for both data types. The US and Germany are the only markets that will see a decrease in incidence rate during the forecast period.

Scope

The Colorectal Cancer (CRC) EpiCast Report and EpiCast Model provide an overview of the risk factors and global trends of CRC in the eight major markets (8MM) (US, France, Germany, Italy, Spain, UK, Japan, and China [urban]). It includes a 10-year epidemiological forecast of the diagnosed incident cases and the five-year diagnosed prevalent cases of CRC in these markets from 2015–2025. The diagnosed incident cases of CRC are further segmented by age, sex, stage at diagnosis, and genetic mutations.

The CRC epidemiology report and model were written and developed by Masters- and PhD-level epidemiologists.

The EpiCast Report is in-depth, high quality, transparent and market-driven, providing expert analysis of disease trends in the 8MM.

The EpiCast Model is easy to navigate, interactive with dashboards, and epidemiology-based with transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over a 10-year forecast period using reputable sources.

Table of Contents

1Table of Contents

1.1List of Tables

1.2List of Figures

2Epidemiology

2.1Disease Background

2.2Risk Factors and Comorbidities

2.3Global Trends

2.3 ...

1Table of Contents

1.1List of Tables

1.2List of Figures

2Epidemiology

2.1Disease Background

2.2Risk Factors and Comorbidities

2.3Global Trends

2.3.18MM Incidence Trends

2.3.28MM, Trends in Five-Year Relative Survival

2.4Forecast Methodology

2.4.1Sources Used Tables

2.4.2Forecast Assumptions and Methods

2.4.3Sources Not Used

2.5Epidemiological Forecast for CRC (2015–2025)

2.5.1Diagnosed Incident Cases of CRC

2.5.2Age-Specific Diagnosed Incident Cases of CRC

2.5.3Sex-Specific Diagnosed Incident Cases of CRC

2.5.4Age-Standardized Diagnosed Incidence of CRC

2.5.5Diagnosed Incident Cases of CRC by Stage at Diagnosis

2.5.6Type of Genetic Mutation among Diagnosed Incident Cases of CRC

2.5.7Five-Year Diagnosed Prevalent Cases of CRC

2.6Discussion

2.6.1Epidemiological Forecast Insight

2.6.2Limitations of the Analysis

2.6.3Strengths of the Analysis

3Appendix

3.1Bibliography

3.2About the Authors

3.2.1Epidemiologists

3.2.2Reviewers

3.2.3Global Director of Therapy Analysis and Epidemiology

3.3About GlobalData

3.4About EpiCast

3.5Disclaimer

List of tables

Table 1: Risk Factors and Comorbidities For CRC

Table 2: 8MM, Five-Year Relative Survival (%)

Table 3: 8MM, Sources Used to Forecast the Diagnosed Incidence of ...

Table 1: Risk Factors and Comorbidities For CRC

Table 2: 8MM, Five-Year Relative Survival (%)

Table 3: 8MM, Sources Used to Forecast the Diagnosed Incidence of CRC

Table 4: 8MM, Sources Used to Forecast the Five-Year Diagnosed Prevalent Cases of CRC

Table 5: 8MM, Sources of CRC Cancer Stage at Diagnosis

Table 6: 8MM, Sources of Genetic Mutations

Table 7: 8MM, Diagnosed Incident Cases of CRC (N), Both Sexes, Ages =18 Years, 2015–2025

Table 8: 8MM, Age-Specific Diagnosed Incident Cases of CRC (N), Both Sexes, Row (%), 2015

Table 9: 8MM, Sex-Specific Diagnosed Incident Cases of CRC (N), Ages =18 Years, Row (%), 2015

Table 10: 8MM, Diagnosed Incident Cases of CRC by Cancer Stage at Diagnosis (N), Ages =18 Years, Row (%), 2015

Table 11: 8MM, Diagnosed Incident Cases of CRC by Type of Genetic Mutation (N), Both Sexes, Ages =18 Years, 2015

Table 12: 8MM, Five-Year Diagnosed Prevalent Cases of CRC (N), Both Sexes, Ages =18 Years, 2015–2025

List of figures

Figure 1: 8MM, Age-Adjusted Incidence Rate for CRC (Cases per 100,000 Population), Men, Ages =15 Years, 1998–2007

Figure 2: 8MM, Age-Adjusted Incidence Rate ...

Figure 1: 8MM, Age-Adjusted Incidence Rate for CRC (Cases per 100,000 Population), Men, Ages =15 Years, 1998–2007

Figure 2: 8MM, Age-Adjusted Incidence Rate for CRC (Cases per 100,000 Population), Women, Ages =15 Years, 1998–2007

Figure 3: 8MM, Diagnosed Incident Cases of CRC (N), Both Sexes, Ages =18 Years, 2015–2025

Figure 4: 8MM, Age-Specific Diagnosed Incident Cases of CRC (N), Both Sexes, Ages =18 Years, 2015

Figure 5: 8MM, Sex-Specific Diagnosed Incident Cases of CRC (N), Ages =18 Years, 2015

Figure 6: 8MM, Age-Standardized Incidence of CRC (Cases per 100,000 Population), Ages =18 Years, by Sex, 2015.

Figure 7: 8MM, Five-Year Diagnosed Prevalent Cases of CRC (N), Both Sexes, Ages =18 Years, 2015–2025

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