Hypereosinophilic Syndrome Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

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The hypereosinophilic syndrome (HES) is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow. HES is a diagnosis of exclusion, after clonal eosinophilia (such as leukemia) and reactive eosinophilia (in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or cancer) have been ruled out.

The Hypereosinophilic Syndrome pipeline drugs market research report provides comprehensive information on the therapeutics under development for Hypereosinophilic Syndrome, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Hypereosinophilic Syndrome and features dormant and discontinued projects.

Hypereosinophilic Syndrome Pipeline Drugs Market Segmentation by Targets

The key targets in the Hypereosinophilic Syndrome pipeline drugs market are Interleukin 5, Cells Expressing Interleukin 3 Receptor Subunit Alpha, Interleukin 5 Receptor Subunit Alpha, Tyrosine Protein Kinase JAK1, and Tyrosine Protein Kinase JAK2.

Hypereosinophilic Syndrome Pipeline Drugs Market Analysis, by Targets

Hypereosinophilic Syndrome Pipeline Drugs Market Analysis, by Targets

For more insights on Hypereosinophilic Syndrome pipeline drugs targets, download a free report sample

Hypereosinophilic Syndrome Pipeline Drugs Market Segmentation by Mechanism of Actions

The key mechanism of actions in the Hypereosinophilic Syndrome pipeline drugs market are Interleukin 5 Inhibitor, Cytotoxic to Cells Expressing Interleukin 3 Receptor Subunit Alpha, Interleukin 5 Receptor Subunit Alpha Antagonist, Tyrosine Protein Kinase JAK1 Inhibitor, and Tyrosine Protein Kinase JAK2 Inhibitor.

Hypereosinophilic Syndrome Pipeline Drugs Market Analysis, by Mechanism of Actions

Hypereosinophilic Syndrome Pipeline Drugs Market Analysis, by Mechanism of Actions

For more insights on Hypereosinophilic Syndrome pipeline drugs mechanism of actions, download a free report sample

Hypereosinophilic Syndrome Pipeline Drugs Market Segmentation by Key Routes of Administration

The key routes of administration in the Hypereosinophilic Syndrome pipeline drugs market are intravenous, subcutaneous, oral, inhalational, parenteral, and topical.

Hypereosinophilic Syndrome Pipeline Drugs Market Analysis, by Routes of Administration

Hypereosinophilic Syndrome Pipeline Drugs Market Analysis, by Routes of Administration

For more insights on Hypereosinophilic Syndrome pipeline drugs routes of administration, download a free report sample

Hypereosinophilic Syndrome Pipeline Drugs Market Segmentation by Key Molecule Types

The key molecule types in the Hypereosinophilic Syndrome pipeline drugs market are monoclonal antibody, small molecule, fusion protein, and protein.

Hypereosinophilic Syndrome Pipeline Drugs Market Analysis, by Molecule Types

Hypereosinophilic Syndrome Pipeline Drugs Market Analysis, by Molecule Types

For more insights on Hypereosinophilic Syndrome pipeline drugs molecule type, download a free report sample

Competitive Landscape

Some of the leading companies in the Hypereosinophilic Syndrome pipeline drugs market are GSK plc, A. Menarini Industrie Farmaceutiche Riunite Srl, Areteia Therapeutics Inc, Incyte Corp, Kyowa Kirin Co Ltd, and Nexeos Bio.

Hypereosinophilic Syndrome Pipeline Drugs Market Analysis, by Companies

Hypereosinophilic Syndrome Pipeline Drugs Market Analysis, by Companies

To know more about the leading players in the Hypereosinophilic Syndrome pipeline drugs market, download a free report sample

Hypereosinophilic Syndrome Pipeline Drugs Market Overview

Key Targets Interleukin 5, Cells Expressing Interleukin 3 Receptor Subunit Alpha, Interleukin 5 Receptor Subunit Alpha, Tyrosine Protein Kinase JAK1, and Tyrosine Protein Kinase JAK2
Key Mechanism of Actions Interleukin 5 Inhibitor, Cytotoxic to Cells Expressing Interleukin 3 Receptor Subunit Alpha, Interleukin 5 Receptor Subunit Alpha Antagonist, Tyrosine Protein Kinase JAK1 Inhibitor, and Tyrosine Protein Kinase JAK2 Inhibitor
Key Routes of Administration Intravenous, Subcutaneous, Oral, Inhalational, Parenteral, and Topical
Key Molecule Types Monoclonal Antibody, Small Molecule, Fusion Protein, and Protein
Leading Companies GSK plc, A. Menarini Industrie Farmaceutiche Riunite Srl, Areteia Therapeutics Inc, Incyte Corp, Kyowa Kirin Co Ltd, and Nexeos Bio

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of Hypereosinophilic Syndrome (Hematological Disorders).
  • The pipeline guide reviews pipeline therapeutics for Hypereosinophilic Syndrome (Hematological Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Hypereosinophilic Syndrome (Hematological Disorders) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Hypereosinophilic Syndrome (Hematological Disorders) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Hypereosinophilic Syndrome (Hematological Disorders)

Reasons to Buy

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Hypereosinophilic Syndrome (Hematological Disorders).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Hypereosinophilic Syndrome (Hematological Disorders) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Hypereosinophilic Syndrome – Overview

Hypereosinophilic Syndrome – Therapeutics Development

Pipeline Overview

Pipeline by Companies

Products under Development by Companies

Hypereosinophilic Syndrome – Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Hypereosinophilic Syndrome – Companies Involved in Therapeutics Development

Hypereosinophilic Syndrome – Drug Profiles

Hypereosinophilic Syndrome – Dormant Projects

Hypereosinophilic Syndrome – Product Development Milestones

Featured News & Press Releases

Nov 17, 2021: European Commission approves Nucala (mepolizumab) in three additional eosinophil-driven diseases

Sep 17, 2021: GSK receives CHMP positive opinions recommending approval of Nucala (mepolizumab) in three additional eosinophil-driven diseases

Sep 15, 2021: NUCALA (mepolizumab) approved in Canada as the first and only biologic treatment for adults with hypereosinophilic syndrome

Jan 15, 2021: Knopp Biosciences reports positive trial results of oral asthma drug

Oct 29, 2020: GSK Nucala (mepolizumab) filings accepted by European Medicines Agency for three additional eosinophil-driven diseases

Sep 28, 2020: GSK’s Nucala receives FDA approval to treat HES

Sep 16, 2020: Knopp Biosciences completes enrollment in phase 2 trial of oral dexpramipexole in eosinophilic asthma

May 27, 2020: FDA grants priority review of Nucala for patients with Hypereosinophilic Syndrome (HES)

Dec 03, 2019: Knopp to start trial enrollment of oral dexpramipexole in H1 2020

Nov 14, 2019: GSK reports positive data for Nucala in late-stage HES trial

Aug 19, 2019: Knopp begins study of dexpramipexole in eosinophilic asthma patients

Jul 09, 2019: Knopp Biosciences to present clinical data for Dexpramipexole at 11th Biennial Symposium of the International Eosinophil Society

Apr 24, 2019: Knopp Biosciences receives FDA Orphan Drug Designation for Dexpramipexole for treatment of Hypereosinophilic Syndrome

Apr 05, 2019: Study finds AstraZeneca’s asthma drug could treat immune disorder

Apr 03, 2019: FDA-approved drug effectively treats rare chronic immune disorder

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Products under Development for Hypereosinophilic Syndrome, 2022

Number of Products under Development by Companies, 2022

Products under Development by Companies, 2022

Number of Products by Stage and Target, 2022

Number of Products by Stage and Mechanism of Action, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Hypereosinophilic Syndrome – Pipeline by A. Menarini Industrie Farmaceutiche Riunite Srl, 2022

Hypereosinophilic Syndrome – Pipeline by Areteia Therapeutics Inc, 2022

Hypereosinophilic Syndrome – Pipeline by GSK plc, 2022

Hypereosinophilic Syndrome – Pipeline by Incyte Corp, 2022

Hypereosinophilic Syndrome – Pipeline by Kyowa Kirin Co Ltd, 2022

Hypereosinophilic Syndrome – Pipeline by Nexeos Bio, 2022

Hypereosinophilic Syndrome – Dormant Projects, 2022

Figures

List of Figures

Number of Products under Development for Hypereosinophilic Syndrome, 2022

Number of Products under Development by Companies, 2022

Number of Products by Top 10 Targets, 2022

Number of Products by Stage and Top 10 Targets, 2022

Number of Products by Top 10 Mechanism of Actions, 2022

Number of Products by Stage and Top 10 Mechanism of Actions, 2022

Number of Products by Top 10 Routes of Administration, 2022

Number of Products by Stage and Top 10 Routes of Administration, 2022

Number of Products by Top 10 Molecule Types, 2022

Number of Products by Stage and Top 10 Molecule Types, 2022

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