Partnerships, Licensing, Investments and M&A Deals and Trends for April 2016 in Pharmaceuticals

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GlobalData's “Partnerships, Licensing, Investments and M&A Deals and Trends for April 2016 in Pharmaceuticals” report is an essential source of data and trend analysis on partnerships, licensing, mergers and acquisitions (M&As) and financings in the pharmaceuticals industry. The report provides detailed information on partnership and licensing transactions, M&As, equity/debt offerings, private equity, and venture financing registered in the pharmaceuticals industry in April 2016. The report portrays detailed comparative data on the number of deals and their value in the last six months, subdivided by deal types, various therapy areas, and geographies. Additionally, the report provides information on the top financial advisory firms in the pharmaceuticals industry. Data presented in this report is derived from GlobalData’s proprietary in-house Pharmaceuticals eTrack deals database and primary and secondary research.

Scope

• Analysis of the market trends for the pharmaceutical industry in the global arena.

• Review of deal trends in the cardiovascular, central nervous system, dermatology, ear nose throat disorders, gastrointestinal, genito urinary system and sex hormones, hematological disorders, hormonal disorders, immunology, infectious disease, male health, metabolic disorders, mouth and dental disorders, musculoskeletal, oncology, ophthalmology, respiratory, toxicology, and women's health segments.

• Analysis of partnerships, licensing, M&As, equity/debt offerings, private equity, and venture financing deals in the pharmaceutical industry.

• Analysis of therapy areas which are very active in terms of venture capital financing, partnerships, licensing agreements, equity/debt offerings, and M&As.

• Analysis of deals based on different payment modes, including upfront and milestone payments, primarily in partnerships and licensing agreements in the pharmaceutical industry.

• Analysis of partnership and licensing deals based on clinical stage of development of products.

• Summary of the pharmaceutical deals globally in the six months.

• Information on the top deals happened in the pharmaceutical industry.

• Geographies covered include – North America, Europe, Asia Pacific, South & Central America, and the Middle East & Africa.

• League tables of financial advisors in M&As and equity/debt offerings. This includes key advisors such as Morgan Stanley, Credit Suisse, and Goldman Sachs.

Reasons to Buy

Enhance your decision making capability in a more rapid and time sensitive manner.

Find out the major deal performing segments for investments in your industry.

Evaluate the types of companies which are entering into partnership or licensing agreements; divesting and acquiring assets.

Identify companies that are aggressively looking to raise capital in the market

Evaluate niche therapy areas that are receiving majority of the upfront and milestone payments in the pharmaceutical industry.

Identify the key venture capitalists, who are financing the pharmaceutical and biotech companies.

Evaluate the clinical development stages where majority of the partnerships and licensing agreements are happening.

Do deals with an understanding of how competitors are financed, and the mergers and partnerships that have shaped the pharmaceutical industry.

Identify growth segments and opportunities in each region within the industry.

Look for key financial advisors where you are planning to raise capital from the market or for acquisitions within the industry.

Table of Contents

1Table of Contents

1Table of Contents2

1.1List of Tables7

1.2List of Figures10

2Pharmaceuticals & Healthcare, Global, Deal Summary13

2.1Pharmaceuticals & Healthcare, Global, Deal Analysis, April 201613

2.2Pharmaceuticals & Healthcare, Global, Major Deals, April 201615

2.2.1AbbVie to Acquire Stemcentrx for up to USD9.8 Billion15

2.2.2Allergan Enters into Licensing Agreement with Heptares Therapeutics16

2.2.3Gilead Sciences Acquires Nimbus Apollo from Nimbus Therapeutics16

2.2.4Zymeworks Enters into Licensing Agreement with GlaxoSmithKline17

2.2.5Argen-X to Partner with AbbVie18

2.3Pharmaceuticals & Healthcare, Global, by Type, Number of Deals, April 201619

2.4Pharmaceuticals & Healthcare, Global, by Type, Deal Values, April 201620

3Pharmaceuticals and Healthcare, Global, Deals, Summary, by Type21

3.1Pharmaceuticals & Healthcare, Global, M&A, April 201621

3.1.1Top M&A Deals in April 201622

3.1.2Pharmaceuticals & Healthcare, Global, M&A Deals by Therapy Area, November 2015 – April 201623

3.2Pharmaceuticals & Healthcare, Global, Equity Offering Deals, April 201624

3.2.1Top Equity Offering Deals in April 201625

3.2.2Pharmaceuticals & Healthcare, Global, Equity Offering Deals by Therapy Area, November 2015 – April 201626

3.3Pharmaceuticals & Healthcare, Global, Private Equity and Venture Capital Deals, April 201627

3.3.1Top PE/VC Deals in April 201628

3.3.2Pharmaceuticals & Healthcare, Global, PE/VC by Therapy Area, April 201629

3.3.3Pharmaceuticals & Healthcare, Global, Venture Capital Deals by Stage of Financing, April 201630

3.3.4Pharmaceuticals & Healthcare, Global, Top Venture Financing Firms, November 2015–April 201632

3.3.5Pharmaceuticals & Healthcare, Global, Top VC Backed Companies, November 2015–April 201633

4Pharmaceuticals & Healthcare, Global, Partnership Deals, April 201634

4.1Pharmaceuticals & Healthcare, Global, Partnership Deals, April 201634

4.2Pharmaceuticals & Healthcare, Global, Partnership Deals by Therapy Area, November 2015 – April 201636

4.3Pharmaceuticals & Healthcare, Global, Partnership Deals by Upfront and Milestone Payments and Deal Values (US$ m), April 201637

4.3.1Pharmaceuticals & Healthcare, Global, Top Partnership Deals by Payment Mode, April 201638

4.4Pharmaceuticals & Healthcare, Global, Partnership Deals by Therapy Area, by Upfront and Milestone Payments and Deal Values (US$ m), November 2015 – April 201639

4.5Pharmaceuticals & Healthcare, Global, Partnership Deals by Phase, Number Of Deals, November 2015 – April 201641

4.6Pharmaceuticals & Healthcare, Global, Partnership Deals by Phase, Deal Values (US$ m), November 2015 – April 201642

4.7Pharmaceuticals & Healthcare, Global, Partnership Deals by Phase, by Upfront & Milestone Payments and Deal Values (US$ m), November 2015 – April 201644

5Pharmaceuticals & Healthcare, Global, Licensing Agreements, April 201646

5.1Pharmaceuticals & Healthcare, Global, Licensing Agreements, April 201646

5.2Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals, Upfront and Milestone Payments and Deal Values (US$ m), April 201648

5.3Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals by Therapy Area, Total Deal Values (US$ m), November 2015 – April 201650

5.4Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals by Therapy Area, Upfront Payments and Milestone Payments (US$ m), November 2015 – April 201652

5.5Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals by Phase, Total Deal Values (US$ m), November 2015 – April 201654

5.6Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals by Phase, Upfront Payments and Milestone Payments (US$ m), November 2015 – April 201657

5.6.1Pharmaceuticals & Healthcare, Global, Top Licensing Agreements by Deal Value, April 201658

5.6.2Pharmaceuticals & Healthcare, Global, Top Licensing Agreements, by Total Upfront Payments, April 201659

5.6.3Pharmaceuticals & Healthcare, Global, Top Licensing Agreements by Total Milestone Payment, April 201660

6Pharmaceuticals & Healthcare, Global, Deal Summary by Therapy Area61

6.1Pharmaceuticals & Healthcare, Global, Oncology Deals, April 201661

6.1.1Oncology – Deals of the Month62

6.2Pharmaceuticals & Healthcare, Global, Central Nervous System Deals, April 201665

6.2.1Central Nervous System – Deals of the Month66

6.3Pharmaceuticals & Healthcare, Global, Infectious Disease Deals, April 201668

6.3.1Infectious Diseases – Deals of the Month69

6.4Pharmaceuticals & Healthcare, Global, Cardiovascular Deals, April 201670

6.4.1Cardiovascular – Deals of the Month71

6.5Pharmaceuticals & Healthcare, Global, Immunology Deals, April 201673

6.5.1Immunology – Deals of the Month74

6.6Pharmaceuticals & Healthcare, Global, Gastrointestinal Deals, April 201676

6.6.1Gastrointestinal – Deal of the Month77

6.7Pharmaceuticals & Healthcare, Global, Metabolic Disorders, Deals, April 201679

6.7.1Metabolic Disorders – Deal of the Month80

7Deal Summary by Geography82

7.1Pharmaceuticals & Healthcare, North America Deals, April 201682

7.1.1North America – Deals of the Month83

7.2Pharmaceuticals & Healthcare, Europe, Deals, April 201685

7.2.1Europe – Deals of the Month86

7.3Pharmaceuticals & Healthcare, Asia-Pacific, Regional Deals, April 201688

7.3.1Asia-Pacific – Deals of the Month89

7.4Pharmaceuticals & Healthcare, Rest of the World, Deals, April 201690

7.4.1Rest of the World – Deals of the Month91

8Pharmaceuticals & Healthcare, Global, Top Financial Advisors92

8.1Pharmaceuticals & Healthcare, Global, Top Financial Advisors, M&A, November 2015 – April 201692

8.2Pharmaceuticals & Healthcare, Global, Top Financial Advisors, Equity Offerings, November 2015 – April 201694

9Further Information96

9.1Methodology96

9.2About GlobalData97

9.3Disclosure information97

9.4Disclaimer98

Table

1.1List of Tables

Table 1:Pharmaceuticals & Healthcare, Global, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201614

Table 2:Pharmaceuticals & Healthcare, Global, Major Deals, April 201615

Table 3:Pharmaceuticals & Healthcare, Global, Number Of Deals and Deal Values (%), April 201620

Table 4:Pharmaceuticals & Healthcare, Global, M&A, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201622

Table 5:Pharmaceuticals & Healthcare, Global, Top M&A Deals, April 201622

Table 6:Pharmaceuticals & Healthcare, Global, M&A, Deals Summary, Number of Deals and Deal Values (US$ m), by Therapy Area, November 2015 – April 201623

Table 7:Pharmaceuticals & Healthcare, Global, Equity Offerings, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201625

Table 8:Pharmaceuticals & Healthcare, Global, Top Equity Offering Deals, April 201625

Table 9:Pharmaceuticals & Healthcare, Global, Equity Offering Deals, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201626

Table 10:Pharmaceuticals & Healthcare, Global, PE/VC, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201628

Table 11:Pharmaceuticals & Healthcare, Global, Top PE/VC Deals, April 201628

Table 12:Pharmaceuticals & Healthcare, Global, PE/VC Deals by Therapy Area, Deals Summary, November 2015 – April 201629

Table 13:Pharmaceuticals & Healthcare, Global, Venture Capital Deals by Stage of Financing, Number Of Deals and Deal Values (%), April 201631

Table 14:Pharmaceuticals & Healthcare, Global, Top Venture Financing Firms, Number of Deals and Deal Values (US$ m), November 2015 – April 201632

Table 15:Pharmaceuticals & Healthcare, Global, Top VC Backed Companies, November 2015 – April 201633

Table 16:Pharmaceuticals & Healthcare, Global, Partnerships, Number of Deals and Deal Values (US$ m), November 2015 – April 201635

Table 17:Pharmaceuticals & Healthcare, Global, Partnership Deals by Therapy Area, Number of Deals and Deal Values (US$ m), November 2015 – April 201636

Table 18:Pharmaceuticals & Healthcare, Partnership Deals, Upfront and Milestone Payments and Deal Values (US$ m), November 2015 – April 201638

Table 19:Pharmaceuticals & Healthcare, Global, Partnerships, Upfront and Milestone Payments and Deal Values (US$ m), April 201638

Table 20:Pharmaceuticals & Healthcare, Global, Partnership Deals by Therapy Area, Upfront and Milestone Payments and Deal Values (US$ m), November 2015 – April 201640

Table 21:Pharmaceuticals & Healthcare, Global, Partnership Deals by Phase, November 2015 – April 201643

Table 22:Pharmaceuticals & Healthcare, Global, Partnership Deals by Upfront and Milestone Payment and Deal values (US$ m), November 2015 – April 201645

Table 23:Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201647

Table 24:Pharmaceuticals & Healthcare, Global, Licensing Agreements, Deals Summary, Upfront and Milestone Payments and Deal Values (US$ m), November 2015 – April 201649

Table 25:Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals by Therapy Area, Number of Deals and Deal Values (US$ m), November 2015 – April 201651

Table 26:Pharmaceuticals & Healthcare, Global, Licensing Agreements by Therapy Area, by Upfront and Milestone Payments (US$ m), April 201653

Table 27:Pharmaceuticals & Healthcare, Global, Partnership Deals by Phase, November 2015 – April 201656

Table 28:Pharmaceuticals & Healthcare, Global, Licensing Agreements by Therapy Area, by Upfront and Milestone Payments and Deal Values (US$ m), April 201658

Table 29:Pharmaceuticals & Healthcare, Global, Top Licensing Agreement Deals by Value, April 201658

Table 30:Pharmaceuticals & Healthcare, Global, Top Licensing Agreement Deals by Total Upfront Payments, April 201659

Table 31:Pharmaceuticals & Healthcare, Global, Top Licensing Agreement Deals by Total Milestone Payment, April 201660

Table 32:Pharmaceuticals & Healthcare, Global, Oncology, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201662

Table 33:Pharmaceuticals & Healthcare, Global, Central Nervous System, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201666

Table 34:Pharmaceuticals & Healthcare, Global, Infectious Diseases, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201669

Table 35:Pharmaceuticals & Healthcare, Global, Cardiovascular, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201671

Table 36:Pharmaceuticals & Healthcare, Global, Immunology, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201674

Table 37:Pharmaceuticals & Healthcare, Global, Gastrointestinal, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201677

Table 38:Pharmaceuticals & Healthcare, Global, Metabolic Disorders, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201680

Table 39:Pharmaceuticals & Healthcare, North America, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201683

Table 40:Pharmaceuticals & Healthcare, Europe, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201686

Table 41:Pharmaceuticals & Healthcare, Asia-Pacific, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201689

Table 42:Pharmaceuticals & Healthcare, Rest of the World, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201691

Table 43:Pharmaceuticals & Healthcare, Top Financial Advisors, M&A, Number of Deals and Deal Values (US$ m), November 2015 – April 201693

Table 44:Pharmaceuticals & Healthcare, Global Top Financial Advisors, Equity Offerings, Number of Deals and Deal Values (US$ m), November 2015 – April 201695

Figures

1.2List of Figures

Figure 1:Pharmaceuticals & Healthcare, Global, Number of Deals and Deal Values (US$ m), November 2015 – April 201613

Figure 2:Pharmaceuticals & Healthcare, Global, Number Of Deals (%), April 201619

Figure 3:Pharmaceuticals & Healthcare, Global, Deal Values (%), April 201620

Figure 4:Pharmaceuticals & Healthcare, Global, M&As, Number of Deals and Deal Values (US$ m), November 2015 – April 201621

Figure 5:Pharmaceuticals & Healthcare, Global, M&As by Therapy Area, Number of Deals and Deal Values (US$ m), by Therapy Area, November 2015 – April 201623

Figure 6:Pharmaceuticals & Healthcare, Global, Equity Offering Deals, Number of Deals and Deal Values (US$ m), November 2015 – April 201624

Figure 7:Pharmaceuticals & Healthcare, Global, Equity Offering Deals by Therapy Area, Number of Deals and Deal Values (US$ m), November 2015 – April 201626

Figure 8:Pharmaceuticals & Healthcare, Global, Private Equity and Venture Capital, Number of Deals and Deal Values (US$ m), November 2015 – April 201627

Figure 9:Pharmaceuticals & Healthcare, Global, PE/VC Deals by Therapy Area, Number of Deals and Deal Values (US$ m), by Therapy Area, November 2015 – April 201629

Figure 10:Pharmaceuticals & Healthcare, Global, Venture Capital Deals by Stage of Financing, Number Of Deals (%), April 201630

Figure 11:Pharmaceuticals & Healthcare, Global, Venture Capital Deals by Stage of Financing, Deal Values (%), April 201631

Figure 12:Pharmaceuticals & Healthcare, Global, Top Venture Financing Firms, Number of Deals and Deal Values (US$ m), November 2015 – April 201632

Figure 13:Pharmaceuticals & Healthcare, Global, Partnerships, Number of Deals and Deal Values (US$ m), November 2015 – April 201634

Figure 14:Pharmaceuticals & Healthcare, Global, Partnership Deals by Therapy Area, Number of Deals and Deal Values (US$ m), November 2015 – April 201636

Figure 15:Pharmaceuticals & Healthcare, Global, Partnership Deals, Upfront and Milestone Payments and Deal Values (US$ m), November 2015 – April 201637

Figure 16:Pharmaceuticals & Healthcare, Global, Partnership Deals by Therapy Area, Upfront and Milestone Payments and Deal Values (US$ m), November 2015 – April 201639

Figure 17:Pharmaceuticals & Healthcare, Global, Partnership Deals by Phase, November 2015 – April 201641

Figure 18:Pharmaceuticals & Healthcare, Global, Partnership Deals by Phase, November 2015 – April 201642

Figure 19:Pharmaceuticals & Healthcare, Global, Partnership Deals by Phase, by Upfront & Milestone Payments and Deal Values (US$ m), November 2015 – April 201644

Figure 20:Pharmaceuticals & Healthcare, Global, Licensing Agreements, Number of Deals and Deal Values (US$ m), November 2015 – April 201646

Figure 21:Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals, Upfront and Milestone Payments and Deal Values (US$ m), November 2015 – April 201648

Figure 22:Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals by Therapy Area, Number of Deals and Deal Values (US$ m), November 2015 – April 201650

Figure 23:Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals by Therapy Area, Upfront and Milestone Payments and Deal Values (US$ m), November 2015 – April 201652

Figure 24:Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals by Phase, Number Of Deals, November 2015 – April 201654

Figure 25:Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals by Phase, Deal Values (US$ m), November 2015 – April 201655

Figure 26:Pharmaceuticals & Healthcare, Global, Licensing Agreement Deals by Phase, by Upfront and Milestone Payments and Deal Values (US$ m), April 201657

Figure 27:Pharmaceuticals & Healthcare, Global, Oncology, Number of Deals and Deal Values (US$ m), November 2015 – April 201661

Figure 28:Pharmaceuticals & Healthcare, Global, Central Nervous System, Number of Deals and Deal Values (US$ m), November 2015 – April 201665

Figure 29:Pharmaceuticals & Healthcare, Global, Infectious Diseases, Number of Deals and Deal Values (US$ m), November 2015 – April 201668

Figure 30:Pharmaceuticals & Healthcare, Global, Cardiovascular, Number of Deals and Deal Values (US$ m), November 2015 – April 201670

Figure 31:Pharmaceuticals & Healthcare, Global, Immunology, Number of Deals and Deal Values (US$ m), November 2015 – April 201673

Figure 32:Pharmaceuticals & Healthcare, Global, Gastrointestinal, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201676

Figure 33:Pharmaceuticals & Healthcare, Global, Metabolic Disorders, Deals Summary, Number of Deals and Deal Values (US$ m), November 2015 – April 201679

Figure 34:Pharmaceuticals & Healthcare, North America, Number of Deals and Deal Values (US$ m), November 2015 – April 201682

Figure 35:Pharmaceuticals & Healthcare, Europe, Number of Deals and Deal Values (US$ m), November 2015 – April 201685

Figure 36:Pharmaceuticals & Healthcare, Asia-Pacific, Number of Deals and Deal Values (US$ m), November 2015 – April 201688

Figure 37:Pharmaceuticals & Healthcare, Rest of the World, Number of Deals and Deal Values (US$ m), November 2015 – April 201690

Figure 38:Pharmaceuticals & Healthcare, Global, Top Financial Advisors, M&A, Number of Deals and Deal Values (US$ m), November 2015 – April 201692

Figure 39:Pharmaceuticals & Healthcare, Global, Top Financial Advisors, Equity Offerings, Number of Deals and Deal Values (US$ m), November 2015 – April 201694

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