Pontine Glioma Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

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Pontine Glioma Pipeline Drugs Market Overview

Pontine gliomas are highly aggressive and difficult-to-treat brain tumors found at the base of the brain. One of the most common types is diffuse intrinsic pontine glioma (DIPG). DIPG affects the pons portion of the brainstem, rendering nervous system function impossible. Symptoms include double vision, inability to close the eyelids completely, dropping one side of the face, and difficulty chewing and swallowing.

The pontine glioma pipeline drugs market research report provides comprehensive information on the therapeutics under development for pontine glioma, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history, and the latest news and press releases. Additionally, the report offers an overview of key players involved in therapeutic development for pontine glioma and features dormant and discontinued projects.

Pontine Glioma Pipeline Drugs Market Segmentation by Targets

Some of the targets of the pontine glioma pipeline drugs market are Cells Expressing CD276 Antigen, Cyclin Dependent Kinase 4, Cyclin Dependent Kinase 6, Histone Deacetylase, Programmed Cell Death Protein 1, Signal Transducer and Activator of Transcription 3, Baculoviral IAP Repeat Containing Protein 5, Cells Expressing Integrin Beta 5, and others.

Pontine Glioma Pipeline Drugs Market Analysis, by Targets

Pontine Glioma Pipeline Drugs Market Analysis, by TargetsFor more Pontine Glioma pipeline drugs market target insights, download a free report sample

Pontine Glioma Pipeline Drugs Market Segmentation by Mechanisms of Action

Some of the key mechanisms of action of the Pontine Glioma pipeline drugs market are Cytotoxic To Cells Expressing CD276 Antigen, Cyclin Dependent Kinase 4 Inhibitor, Cyclin Dependent Kinase 6 Inhibitor, Histone Deacetylase Inhibitor, Programmed Cell Death Protein 1 Antagonist, Signal Transducer And Activator Of Transcription 3 Inhibitor, Cytotoxic To Cells Expressing Integrin Beta 5, Cytotoxic To Cells Expressing Wilms Tumor Protein, and others.

Pontine Glioma Pipeline Drugs Market Analysis, by Mechanisms of Action

Pontine Glioma Pipeline Drugs Market Analysis, by Mechanisms of Action

 For more mechanisms of action insights into the Pontine Glioma pipeline drugs market, download a free report sample

Pontine Glioma Pipeline Drugs Market Segmentation by Routes of Administration

The key routes of administration in the Pontine Glioma pipeline drugs market are oral, intravenous, intratumor, subcutaneous, intraperitoneal, intradermal, intracerebral, intravenous drip, and others.

Pontine Glioma Pipeline Drugs Market Analysis, by Routes of Administration

Pontine Glioma Pipeline Drugs Market Analysis, by Routes of Administration

For more routes of administration insights into the Pontine Glioma pipeline drugs market, download a free report sample

Pontine Glioma Pipeline Drugs Market Segmentation by Molecule Types

The molecule types in the Pontine Glioma pipeline drugs market are Small Molecule, Monoclonal Antibody, Subunit Vaccine, Cell Therapy, Gene-Modified Cell Therapy, Monoclonal Antibody Conjugated, Antisense Oligonucleotide, Fusion Protein, and others.

Pontine Glioma Pipeline Drugs Market Analysis, by Molecule Types

Pontine Glioma Pipeline Drugs Market Analysis, by Molecule Types

For more molecule type insights into the Pontine Glioma pipeline drugs market, download a free report sample

Pontine Glioma Pipeline Drugs Market - Competitive Landscape

Some of the key companies in the Pontine Glioma pipeline drugs market are Bristol-Myers Squibb Co, Accendatech Co Ltd, DNAtrix Inc, Midatech Pharma Plc, Novartis AG, Y-mAbs Therapeutics Inc, A. Menarini Industrie Farmaceutiche Riunite Srl, Aminex Therapeutics Inc, Apexigen Inc, and others.

Pontine Glioma Pipeline Drugs Market Analysis, by Companies

Pontine Glioma Pipeline Drugs Market Analysis, by Companies

To know more about the Pontine Glioma pipeline drugs market companies, download a free report sample

Pontine Glioma Pipeline Drugs Market Report Overview

Key Targets Cells Expressing CD276 Antigen, Cyclin Dependent Kinase 4, Cyclin Dependent Kinase 6, Histone Deacetylase, Programmed Cell Death Protein 1, Signal Transducer and Activator Of Transcription 3, Baculoviral IAP Repeat Containing Protein 5, Cells Expressing Integrin Beta 5, and Others
Key Mechanisms of Action Cytotoxic To Cells Expressing CD276 Antigen, Cyclin Dependent Kinase 4 Inhibitor, Cyclin Dependent Kinase 6 Inhibitor, Histone Deacetylase Inhibitor, Programmed Cell Death Protein 1 Antagonist, Signal Transducer and Activator Of Transcription 3 Inhibitor, Cytotoxic To Cells Expressing Integrin Beta 5, Cytotoxic To Cells Expressing Wilms Tumor Protein, and Others
Key Routes of Administration Oral, Intravenous, Intratumor, Subcutaneous, Intraperitoneal, Intradermal, Intracerebral, Intravenous Drip, and Others
Key Molecule Types Small Molecule, Monoclonal Antibody, Subunit Vaccine, Cell Therapy, Gene-Modified Cell Therapy, Monoclonal Antibody Conjugated, Antisense Oligonucleotide, Fusion Protein, and Others
Key Companies Bristol-Myers Squibb Co, Accendatech Co Ltd, DNAtrix Inc, Midatech Pharma Plc, Novartis AG, Y-mAbs Therapeutics Inc, A. Menarini Industrie Farmaceutiche Riunite Srl, Aminex Therapeutics Inc, Apexigen Inc, and Others

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of Pontine Glioma.
  • The pipeline guide reviews pipeline therapeutics for Pontine Glioma by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration to discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Pontine Glioma therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Pontine Glioma therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA), and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews the latest news related to pipeline therapeutics for Pontine Glioma

Reasons to Buy

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with a potentially strong product portfolio and create effective counterstrategies to gain a competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Pontine Glioma.
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and their most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding the Pontine Glioma pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understanding from the know-how what drove them from the pipeline.

A. Menarini Industrie Farmaceutiche Riunite Srl
Accendatech Co Ltd
Aminex Therapeutics Inc
Apexigen Inc
Bayer AG
Bexion Pharmaceuticals LLC
BioMarin Pharmaceutical Inc
Bionaut Labs Inc
Bristol-Myers Squibb Co
CDG Therapeutics Inc
Chimerix Inc
Cothera Bioscience Pty Ltd
Curis Inc
DNAtrix Inc
Eisai Co Ltd
Eli Lilly and Co
Exelixis Inc
F. Hoffmann-La Roche Ltd
Gate2Brain SL
ImmunityBio Inc
Immunomic Therapeutics Inc
Incuron
InnoMab Pte Ltd
Karyopharm Therapeutics Inc
Kazia Therapeutics Ltd
Lumos Pharma Inc
M4K Pharma Inc
Mana Therapeutics Inc
Medicenna Therapeutics Corp
Midatech Pharma Plc
MimiVax LLC
Moleculin Biotech Inc
Novartis AG
Oblato Inc
OncoRx Pharmaceuticals Inc
Oncotelic Therapeutics Inc
Ono Pharmaceutical Co Ltd
Pfizer Inc
Plus Therapeutics Inc
PTC Therapeutics Inc
Regeneron Pharmaceuticals Inc
Secura Bio Inc
Shionogi & Co Ltd
TCR Cure Biopharma Technology Co Ltd
Tmunity Therapeutics Inc
Xcovery Holding Co LLC
Y-mAbs Therapeutics Inc

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Pontine Glioma – Overview

Pontine Glioma – Therapeutics Development

Pipeline Overview

Pipeline by Companies

Pipeline by Universities/Institutes

Products under Development by Companies

Products under Development by Universities/Institutes

Pontine Glioma – Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Pontine Glioma – Companies Involved in Therapeutics Development

Pontine Glioma – Drug Profiles

8H-9 – Drug Profile

Product Description

Mechanism Of Action

abemaciclib – Drug Profile

Product Description

Mechanism Of Action

ACT-001 – Drug Profile

Product Description

Mechanism Of Action

Alocelyvir – Drug Profile

Product Description

Mechanism Of Action

AMXT-1501 + eflornithine hydrochloride – Drug Profile

Product Description

Mechanism Of Action

BXQ-350 – Drug Profile

Product Description

Mechanism Of Action

Cabometyx – Drug Profile

Product Description

Mechanism Of Action

CBL-0137 – Drug Profile

Product Description

Mechanism Of Action

Cellular Immunotherapy for Diffuse Intrinsic Pontine Glioma and Glioblastoma – Drug Profile

Product Description

Mechanism Of Action

Cellular Immunotherapy for Oncology – Drug Profile

Product Description

Mechanism Of Action

Cellular Immunotherapy for Pediatric Diffuse Intrinsic Pontine Glioma – Drug Profile

Product Description

Mechanism Of Action

Cellular Immunotherapy for Pontine Glioma – Drug Profile

Product Description

Mechanism Of Action

cemiplimab – Drug Profile

Product Description

Mechanism Of Action

cobimetinib fumarate – Drug Profile

Product Description

Mechanism Of Action

disufenton sodium – Drug Profile

Product Description

Mechanism Of Action

doxorubicin – Drug Profile

Product Description

Mechanism Of Action

ensartinib hydrochloride – Drug Profile

Product Description

Mechanism Of Action

everolimus – Drug Profile

Product Description

Mechanism Of Action

fimepinostat – Drug Profile

Product Description

Mechanism Of Action

G2B-001 – Drug Profile

Product Description

Mechanism Of Action

Gene Therapy for Diffuse Intrinsic Pontine Glioma – Drug Profile

Product Description

Mechanism Of Action

Gene Therapy to Target B7H3 for CNS Tumor – Drug Profile

Product Description

Mechanism Of Action

Gene Therapy to Target GD-2 for Pediatric Diffuse Intrinsic Pontine Glioma – Drug Profile

Product Description

Mechanism Of Action

Gene Therapy to Target WT1 for Oncology – Drug Profile

Product Description

Mechanism Of Action

indoximod – Drug Profile

Product Description

Mechanism Of Action

ipilimumab + nivolumab – Drug Profile

Product Description

Mechanism Of Action

Kid EDV – Drug Profile

Product Description

Mechanism Of Action

larotrectinib sulfate – Drug Profile

Product Description

Mechanism Of Action

lenvatinib mesylate – Drug Profile

Product Description

Mechanism Of Action

MANA-677679 – Drug Profile

Product Description

Mechanism Of Action

marizomib – Drug Profile

Product Description

Mechanism Of Action

MDNA-55 – Drug Profile

Product Description

Mechanism Of Action

Monoclonal Antibody Conjugate to Target B7H3 for Pediatric Diffuse Intrinsic Pontine Glioma – Drug Profile

Product Description

Mechanism Of Action

nimotuzumab – Drug Profile

Product Description

Mechanism Of Action

nivolumab – Drug Profile

Product Description

Mechanism Of Action

omburtamab – Drug Profile

Product Description

Mechanism Of Action

ONC-201 – Drug Profile

Product Description

Mechanism Of Action

ORX-101 – Drug Profile

Product Description

Mechanism Of Action

P-28 – Drug Profile

Product Description

Mechanism Of Action

palbociclib – Drug Profile

Product Description

Mechanism Of Action

panobinostat – Drug Profile

Product Description

Mechanism Of Action

panobinostat SR – Drug Profile

Product Description

Mechanism Of Action

paxalisib – Drug Profile

Product Description

Mechanism Of Action

pomalidomide – Drug Profile

Product Description

Mechanism Of Action

RG-2833 – Drug Profile

Product Description

Mechanism Of Action

ribociclib succinate – Drug Profile

Product Description

Mechanism Of Action

RNL – Drug Profile

Product Description

Mechanism Of Action

S-588410 – Drug Profile

Product Description

Mechanism Of Action

selinexor – Drug Profile

Product Description

Mechanism Of Action

SL-701 – Drug Profile

Product Description

Mechanism Of Action

Small Molecules to Inhibit ACVR1 for Pediatric Diffuse Intrinsic Pontine Glioma – Drug Profile

Product Description

Mechanism Of Action

sotigalimab – Drug Profile

Product Description

Mechanism Of Action

SurVaxM – Drug Profile

Product Description

Mechanism Of Action

tasadenoturev – Drug Profile

Product Description

Mechanism Of Action

trabedersen – Drug Profile

Product Description

Mechanism Of Action

unesbulin – Drug Profile

Product Description

Mechanism Of Action

Vaccine for Glioma – Drug Profile

Product Description

Mechanism Of Action

Vaccine for Pontine Glioma – Drug Profile

Product Description

Mechanism Of Action

Vaccine to Target CMV Antigen for Central Nervous System Cancer – Drug Profile

Product Description

Mechanism Of Action

WP-1066 – Drug Profile

Product Description

Mechanism Of Action

zotiraciclib citrate – Drug Profile

Product Description

Mechanism Of Action

Pontine Glioma – Dormant Projects

Pontine Glioma – Discontinued Products

Pontine Glioma – Product Development Milestones

Featured News & Press Releases

Nov 20, 2022: Oncotelic prresenting data for OT101 against diffuse intrinsic pontine glioma (DIPG) at the 2022 Society for Neuro-Oncology (SNO) Annual Meeting

Oct 06, 2022: PNOC clinical study of kazia’s paxalisib in childhood brain cancer expands internationally

Jun 21, 2022: Orphan Designation granted by EMA to MTX110 development for the treatment of Glioma

Jun 15, 2022: Midatech Pharma : An update to MTX110 study in pediatric patients with DIPG to be presented at The International Symposium on Pediatric Neuro-Oncology, Hamburg, Germany (ISPNO 2022)

Nov 22, 2021: DNAtrix announces oral presentation of positive overall survival data with DNX-2401 in DIPG at the Society for Neuro-oncology (SNO) annual meeting

Aug 13, 2021: Plus Therapeutics to present data from ReSPECT-GBM trial at the American Association of Neurological Surgeons 2021 Annual Scientific Meeting

Jul 19, 2021: Oblato announces that it has received a positive response from the FDA for the use of OKN-007 for patients with high-grade gliomas in an expanded access program

Jul 07, 2021: The new immunomodulator ACT001 shows great potential

Apr 29, 2021: Y-mAbs announces Omburtamab data to be presented at 2021 ASCO annual meeting

Mar 25, 2021: Midatech Pharma announces MTX110 update & headline results for 2020

Mar 03, 2021: Oblato announces Fast Track Designation of OKN-007 for diffuse intrinsic pontine glioma from the FDA

Dec 11, 2020: Midatech Pharma announces MTX110 Ppogrammes to be presented at ISPNO 2020

Dec 10, 2020: Oblato announces discussion outcome with FDA for development of OKN-007 for diffuse intrinsic pontine glioma

Dec 10, 2020: Kazia to collaborate with Pacific Pediatric Neuro-Oncology Consortium (PNOC) for new Paxalisib combination study in DIPG

Dec 01, 2020: Moleculin announces FDA approves 3 rare pediatric disease designations for WP1066

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Products under Development for Pontine Glioma, 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Universities/Institutes, 2022

Products under Development by Companies, 2022

Products under Development by Universities/Institutes, 2022

Number of Products by Stage and Target, 2022

Number of Products by Stage and Mechanism of Action, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Pontine Glioma – Dormant Projects, 2022

Pontine Glioma – Discontinued Products, 2022

Figures

List of Figures

Number of Products under Development for Pontine Glioma, 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Universities/Institutes, 2022

Number of Products by Top 10 Targets, 2022

Number of Products by Stage and Top 10 Targets, 2022

Number of Products by Top 10 Mechanism of Actions, 2022

Number of Products by Stage and Top 10 Mechanism of Actions, 2022

Number of Products by Top 10 Routes of Administration, 2022

Number of Products by Stage and Top 10 Routes of Administration, 2022

Number of Products by Top 10 Molecule Types, 2022

Number of Products by Stage and Top 10 Molecule Types, 2022

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