Primary Sclerosing Cholangitis Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

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The Primary Sclerosing Cholangitis pipeline market research report provides comprehensive information on the therapeutics under development for Primary Sclerosing Cholangitis, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Primary Sclerosing Cholangitis and features dormant and discontinued projects.

What are the key targets in the Primary Sclerosing Cholangitis pipeline market?

The key targets in the Primary Sclerosing Cholangitis pipeline market are Ileal Sodium/Bile Acid Cotransporter, Integrin Beta 6, Integrin Alpha V, Integrin Beta 1, Prostaglandin G/H Synthase 2, Transforming Growth Factor Beta 1, Bile Acid Receptor, Bile Salt Export Pump, Integrin Alpha 5, and C-C Motif Chemokine 24. Ileal Sodium/Bile Acid Cotransporter has the highest number of pipeline products in the Primary Sclerosing Cholangitis pipeline market.

What are the key targets in the Primary Sclerosing Cholangitis pipeline market

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What are the key MoA in the Primary Sclerosing Cholangitis pipeline market?

The key MoA in the Primary Sclerosing Cholangitis pipeline market are Ileal Sodium/Bile Acid Cotransporter Inhibitor, Integrin Beta 6 Antagonist, Integrin Alpha V Antagonist, Integrin Beta 1 Antagonist, Prostaglandin G/H Synthase 2 Inhibitor, Transforming Growth Factor Beta 1 Inhibitor, Bile Acid Receptor Agonist, Bile Salt Export Pump Inhibitor, Integrin Alpha 5 Antagonist, and C-C Motif Chemokine 24 Inhibitor. Ileal Sodium/Bile Acid Cotransporter Inhibitor has the highest number of pipeline products in the Primary Sclerosing Cholangitis pipeline market.

Primary Sclerosing Cholangitis pipeline market, by MoA

Primary Sclerosing Cholangitis pipeline market, by MoA

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What are the key RoA in the Primary Sclerosing Cholangitis pipeline market?

The key RoA in the Primary Sclerosing Cholangitis pipeline market are oral, intravenous, subcutaneous, inhalational, intradermal, intratumor, and topical. Oral has the highest number of pipeline product in the Primary Sclerosing Cholangitis pipeline market.

Primary Sclerosing Cholangitis pipeline market, by RoA

Primary Sclerosing Cholangitis pipeline market, by RoA

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What are the key molecule type in the Primary Sclerosing Cholangitis pipeline market?

The key molecule type in the Primary Sclerosing Cholangitis pipeline market are Small Molecule, Antisense RNAi Oligonucleotide, Biologic, Recombinant Protein, Cell Therapy, Monoclonal Antibody, Peptide, Subunit Vaccine, and Synthetic Peptide. Small Molecule has the highest number of pipeline products in the Primary Sclerosing Cholangitis pipeline market.

Primary Sclerosing Cholangitis pipeline market, by molecule type

Primary Sclerosing Cholangitis pipeline market, by molecule type

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Which are the key companies in the Primary Sclerosing Cholangitis pipeline market?

The key companies in the Primary Sclerosing Cholangitis pipeline market are Pliant Therapeutics Inc, Sirnaomics Inc, Albireo Pharma Inc, HighTide Therapeutics Inc, Mirum Pharmaceuticals Inc, Qing Bile Therapeutics Inc, AbbVie Inc, Avolynt Inc, BiomX Inc, Cadila Healthcare Ltd, Cascade Pharmaceuticals Inc, and Chemomab Therapeutics Ltd.

Primary Sclerosing Cholangitis pipeline market, by companies

Primary Sclerosing Cholangitis pipeline market, by companies

To know more about key companies, download a free report sample

Market report overview

Key target Ileal Sodium/Bile Acid Cotransporter, Integrin Beta 6, Integrin Alpha V, Integrin Beta 1, Prostaglandin G/H Synthase 2, Transforming Growth Factor Beta 1, Bile Acid Receptor, Bile Salt Export Pump, Integrin Alpha 5, and C-C Motif Chemokine 24
Key MoA Ileal Sodium/Bile Acid Cotransporter Inhibitor, Integrin Beta 6 Antagonist, Integrin Alpha V Antagonist, Integrin Beta 1 Antagonist, Prostaglandin G/H Synthase 2 Inhibitor, Transforming Growth Factor Beta 1 Inhibitor, Bile Acid Receptor Agonist, Bile Salt Export Pump Inhibitor, Integrin Alpha 5 Antagonist, and C-C Motif Chemokine 24 Inhibitor
Key RoA Oral, Intravenous, Subcutaneous, Inhalational, Intradermal, Intratumor, and Topical
Key molecule type Small Molecule, Antisense RNAi Oligonucleotide, Biologic, Recombinant Protein, Cell Therapy, Monoclonal Antibody, Peptide, Subunit Vaccine, and Synthetic Peptide
Key companies Pliant Therapeutics Inc, Sirnaomics Inc, Albireo Pharma Inc, HighTide Therapeutics Inc, Mirum Pharmaceuticals Inc, Qing Bile Therapeutics Inc, AbbVie Inc, Avolynt Inc, BiomX Inc, Cadila Healthcare Ltd, Cascade Pharmaceuticals Inc, and Chemomab Therapeutics Ltd

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of Primary Sclerosing Cholangitis (Gastrointestinal).
  • The pipeline guide reviews pipeline therapeutics for Primary Sclerosing Cholangitis (Gastrointestinal) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Primary Sclerosing Cholangitis (Gastrointestinal) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Primary Sclerosing Cholangitis (Gastrointestinal) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Primary Sclerosing Cholangitis (Gastrointestinal)

Reasons to Buy

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Primary Sclerosing Cholangitis (Gastrointestinal).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Primary Sclerosing Cholangitis (Gastrointestinal) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

AbbVie Inc
Albireo Pharma Inc
Avolynt Inc
BiomX Inc
Cadila Healthcare Ltd
Cascade Pharmaceuticals Inc
Chemomab Therapeutics Ltd
CymaBay Therapeutics Inc
Dr. Falk Pharma GmbH
Emergent Biotechnologies LLC
Engitix Ltd
Escient Pharmaceuticals Inc
Gilead Sciences Inc
Hanmi Pharmaceuticals Co Ltd
HighTide Therapeutics Inc
Iltoo Pharma
Immunic Inc
Intercept Pharmaceuticals Inc
LISCure Biosciences Co Ltd
Mirum Pharmaceuticals Inc
NGM Biopharmaceuticals Inc
Orbsen Therapeutics Ltd
Parvus Therapeutics Inc
Pliant Therapeutics Inc
Qing Bile Therapeutics Inc
Scohia Pharma Inc
Sirnaomics Inc
Takeda Pharmaceutical Co Ltd
Yungjin Pharm Co Ltd

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Primary Sclerosing Cholangitis – Overview

Primary Sclerosing Cholangitis – Therapeutics Development

Pipeline Overview

Pipeline by Companies

Pipeline by Universities/Institutes

Products under Development by Companies

Products under Development by Universities/Institutes

Primary Sclerosing Cholangitis – Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Primary Sclerosing Cholangitis – Companies Involved in Therapeutics Development

AbbVie Inc

Albireo Pharma Inc

Avolynt Inc

BiomX Inc

Cadila Healthcare Ltd

Cascade Pharmaceuticals Inc

Chemomab Therapeutics Ltd

CymaBay Therapeutics Inc

Dr. Falk Pharma GmbH

Emergent Biotechnologies LLC

Engitix Ltd

Escient Pharmaceuticals Inc

Gilead Sciences Inc

Hanmi Pharmaceuticals Co Ltd

HighTide Therapeutics Inc

Iltoo Pharma

Immunic Inc

Intercept Pharmaceuticals Inc

LISCure Biosciences Co Ltd

Mirum Pharmaceuticals Inc

NGM Biopharmaceuticals Inc

Orbsen Therapeutics Ltd

Parvus Therapeutics Inc

Pliant Therapeutics Inc

Qing Bile Therapeutics Inc

Scohia Pharma Inc

Sirnaomics Inc

Takeda Pharmaceutical Co Ltd

Yungjin Pharm Co Ltd

Primary Sclerosing Cholangitis – Drug Profiles

A-3907 – Drug Profile

Product Description

Mechanism Of Action

History of Events

aldafermin – Drug Profile

Product Description

Mechanism Of Action

History of Events

aldesleukin – Drug Profile

Product Description

Mechanism Of Action

History of Events

AVO-1681 – Drug Profile

Product Description

Mechanism Of Action

B7-33 – Drug Profile

Product Description

Mechanism Of Action

History of Events

berberine ursodeoxycholate – Drug Profile

Product Description

Mechanism Of Action

History of Events

Biologic for Primary Sclerosing Cholangitis – Drug Profile

Product Description

Mechanism Of Action

History of Events

BX-003 – Drug Profile

Product Description

Mechanism Of Action

History of Events

Cilofexor – Drug Profile

Product Description

Mechanism Of Action

History of Events

CM-101 – Drug Profile

Product Description

Mechanism Of Action

History of Events

CS-0159 – Drug Profile

Product Description

Mechanism Of Action

History of Events

Drugs for Gastrointestinal Diseases – Drug Profile

Product Description

Mechanism Of Action

EP-547 – Drug Profile

Product Description

Mechanism Of Action

History of Events

HM-15211 – Drug Profile

Product Description

Mechanism Of Action

History of Events

HTD-1801 – Drug Profile

Product Description

Mechanism Of Action

History of Events

maralixibat chloride – Drug Profile

Product Description

Mechanism Of Action

History of Events

MB-12066 – Drug Profile

Product Description

Mechanism Of Action

History of Events

MORF Beta6-2 – Drug Profile

Product Description

Mechanism Of Action

History of Events

norursodeoxycholic acid – Drug Profile

Product Description

Mechanism Of Action

History of Events

obeticholic acid – Drug Profile

Product Description

Mechanism Of Action

History of Events

odevixibat – Drug Profile

Product Description

Mechanism Of Action

History of Events

PLN-1177 – Drug Profile

Product Description

Mechanism Of Action

History of Events

PLN-1561 – Drug Profile

Product Description

Mechanism Of Action

History of Events

PLN-1705 – Drug Profile

Product Description

Mechanism Of Action

History of Events

PLN-74809 – Drug Profile

Product Description

Mechanism Of Action

History of Events

PVT-201 – Drug Profile

Product Description

Mechanism Of Action

QBT-002 – Drug Profile

Product Description

Mechanism Of Action

QBT-006 – Drug Profile

Product Description

Mechanism Of Action

saroglitazar – Drug Profile

Product Description

Mechanism Of Action

History of Events

SC-435 – Drug Profile

Product Description

Mechanism Of Action

History of Events

SCO-240 – Drug Profile

Product Description

Mechanism Of Action

History of Events

seladelpar lysine – Drug Profile

Product Description

Mechanism Of Action

History of Events

Small Molecules to Inhibit NTCP for Infectious Diseases and Unspecified Metabolic Diseases – Drug Profile

Product Description

Mechanism Of Action

Stem Cell Therapy for Gastrointestinal, Infectious and Respiratory Disease – Drug Profile

Product Description

Mechanism Of Action

History of Events

STP-705 – Drug Profile

Product Description

Mechanism Of Action

History of Events

STP-707 – Drug Profile

Product Description

Mechanism Of Action

vidofludimus calcium – Drug Profile

Product Description

Mechanism Of Action

History of Events

volixibat potassium – Drug Profile

Product Description

Mechanism Of Action

History of Events

Primary Sclerosing Cholangitis – Dormant Projects

Primary Sclerosing Cholangitis – Discontinued Products

Primary Sclerosing Cholangitis – Product Development Milestones

Featured News & Press Releases

Feb 22, 2022: HighTide Therapeutics announces end-of-phase 2 meeting with FDA and agreement to Proceed to phase 3 for HTD1801 for the treatment of PSC

Feb 16, 2022: Sirnaomics receives safe to proceed letter for U.S. FDA investigational new drug application for systemic RNAi therapeutic STP707 in primary sclerosing cholangitis (PSC)

Dec 02, 2021: Chemomab announces FDA clearance of its IND application for CM-101, a first-in-class CCL24 neutralizing antibody for the treatment of primary sclerosing cholangitis

Nov 10, 2021: Chemomab announces poster presentation at AASLD’s The Liver Meeting 2021

Oct 28, 2021: HighTide Therapeutics to present new PSC and NASH clinical data at AASLD 2021

Jun 24, 2021: Korea-US innovative bio-drug confirms the possibility of treating various rare liver diseases

Jun 23, 2021: Mirum Pharmaceuticals presents analyses from volixibat at the EASL International Liver Congress 2021

Jun 21, 2021: HighTide Therapeutics announces the presentation of topline results of phase 2 study of HTD1801 in PSC patients at the International Liver Congress 2021

Jun 16, 2021: Mirum Pharmaceuticals to showcase analyses from volixibat at The International Liver Congress 2021

Jun 10, 2021: Chemomab announces poster presentation at the International Liver Congress 2021 (EASL)

May 28, 2021: SCOHIA initiates a phase 1 study on an SSTR5 antagonist (SCO-240)

May 18, 2021: BiomX to host key opinion leader event on BX003 for the treatment of inflammatory bowel disease

May 12, 2021: Korea-US LAPS Triple Agonist additionally designated as orphan drug by US FDA

Mar 31, 2021: Immunic and 4SC AG sign agreement regarding the settlement of royalty obligations for Immunic’s lead program, IMU-838

Mar 25, 2021: Albireo announces first patients dosed in phase 1 study with new product candidate A3907

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Products under Development for Primary Sclerosing Cholangitis, 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Companies, 2022 (Contd..1)

Number of Products under Development by Universities/Institutes, 2022

Products under Development by Companies, 2022

Products under Development by Companies, 2022 (Contd..1)

Products under Development by Companies, 2022 (Contd..2)

Products under Development by Universities/Institutes, 2022

Number of Products by Stage and Target, 2022

Number of Products by Stage and Mechanism of Action, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Primary Sclerosing Cholangitis – Pipeline by AbbVie Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Albireo Pharma Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Avolynt Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by BiomX Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Cadila Healthcare Ltd, 2022

Primary Sclerosing Cholangitis – Pipeline by Cascade Pharmaceuticals Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Chemomab Therapeutics Ltd, 2022

Primary Sclerosing Cholangitis – Pipeline by CymaBay Therapeutics Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Dr. Falk Pharma GmbH, 2022

Primary Sclerosing Cholangitis – Pipeline by Emergent Biotechnologies LLC, 2022

Primary Sclerosing Cholangitis – Pipeline by Engitix Ltd, 2022

Primary Sclerosing Cholangitis – Pipeline by Escient Pharmaceuticals Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Gilead Sciences Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Hanmi Pharmaceuticals Co Ltd, 2022

Primary Sclerosing Cholangitis – Pipeline by HighTide Therapeutics Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Iltoo Pharma, 2022

Primary Sclerosing Cholangitis – Pipeline by Immunic Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Intercept Pharmaceuticals Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by LISCure Biosciences Co Ltd, 2022

Primary Sclerosing Cholangitis – Pipeline by Mirum Pharmaceuticals Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by NGM Biopharmaceuticals Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Orbsen Therapeutics Ltd, 2022

Primary Sclerosing Cholangitis – Pipeline by Parvus Therapeutics Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Pliant Therapeutics Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Qing Bile Therapeutics Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Scohia Pharma Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Sirnaomics Inc, 2022

Primary Sclerosing Cholangitis – Pipeline by Takeda Pharmaceutical Co Ltd, 2022

Primary Sclerosing Cholangitis – Pipeline by Yungjin Pharm Co Ltd, 2022

Primary Sclerosing Cholangitis – Dormant Projects, 2022

Primary Sclerosing Cholangitis – Discontinued Products, 2022

Figures

List of Figures

Number of Products under Development for Primary Sclerosing Cholangitis, 2022

Number of Products under Development by Companies, 2022

Number of Products by Top 10 Targets, 2022

Number of Products by Stage and Top 10 Targets, 2022

Number of Products by Top 10 Mechanism of Actions, 2022

Number of Products by Stage and Top 10 Mechanism of Actions, 2022

Number of Products by Routes of Administration, 2022

Number of Products by Stage and Routes of Administration, 2022

Number of Products by Molecule Types, 2022

Number of Products by Stage and Molecule Types, 2022

Frequently asked questions

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