Type 2 Diabetes Market Size and Trend Report including Epidemiology, Disease Management, Pipeline Analysis, Competitor Assessment, Unmet Needs, Clinical Trial Strategies and Forecast, 2019-2029

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Type 2 Diabetes Market Report Overview

The T2D market size across the 7MM was valued at $2.43 billion in 2021 and will achieve a CAGR of more than 31% during 2021-2031. The diabetic population is set to grow in line with the increased prevalence of risk factors such as obesity, which will drive market growth during the forecast period.

Type 2 Diabetes Market Outlook, 2021-2031 ($ Billion)

Type 2 Diabetes Market Outlook, 2021-2031 ($ Billion)

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The T2D market research covers the 7MM (France, Germany, Italy, Spain, and the UK) and provides a forecast model for the T2D market through 2031.

Market Size (2021) $2.43 billion
CAGR (2021-2031) >31%
Leading Players ·       Takeda

·       GSK

·       AstraZeneca

·       Novo Nordisk

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Type 2 Diabetes Market Insights

The expiry of established brands, such as Saxenda, leaves these products vulnerable to sales erosion thereby hampering the market growth. However, therapies with new routes of will administration enter the market such as Novo Nordisk’s oral semaglutide (NN-9932), Eli Lilly’s orforglipron, and Pfizer’s PF-07081532 and danuglipron tromethamine, which will propel the market growth in the coming years.

Type 2 Diabetes - Treatment Insights

  • Many of the activities in the developed world promote overindulgence while facilitating sedentary behaviours, leading to an imbalance where there is a juxtaposing surplus in calories consumed and a deficit in calories expended, which is a predisposition to weight gain in the long term. Therefore, as a chronic condition, obesity necessitates timely diagnosis and treatment.
  • Clinical practice favors conservative treatment options relying on behavioral modification for patients with Class I and Class II obesity.
  • Interventional treatment options are offered to patients with obesity. For instance, Roux-en-Y gastric bypass, biliopancreatic diversion with duodenal switch (BDP/DS), and sleeve gastrectomy collectively comprise the various types of bariatric surgery, a procedure in which stomach size is reduced to limit the amount of food eaten by the individual and decrease nutrient absorption.

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Type 2 Diabetes Market - Competitive Landscape

Takeda was the leading sponsor of cell therapy trials in T2D market in 2019.

A few of the leading players in the T2D market are:

  • Takeda
  • GSK
  • AstraZeneca
  • Novo Nordisk

Type 2 Diabetes Market Analysis by Companies

Type 2 Diabetes Market Analysis by Companies

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Reasons to Buy

  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the 7MM T2D therapeutics market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the 7MM T2D therapeutics market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counterstrategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and strategic partnerships.

Eli Lilly
Novo Nordisk
Sanofi
AstraZeneca
Merck & Co.
Boehringer Ingelheim
GlaxoSmithKline
Takeda
Roche
Pfizer
Johnson & Johnson
Novartis
Theracos
Lexicon Pharmaceuticals
Hua Medicine Shanghai Ltd
Tonghua Dongbao Pharmaceutical Co Ltd
Jiangsu Hengrui Medicine Co Ltd.
Sihuan Pharmaceutical Holdings Group
Biocon Ltd
Oramed Pharamceuticals

Table of Contents

| Contents

| List of Tables

| List of Figures

| About GlobalData

1 Type 2 Diabetes (T2D): Executive Summary – Updated Dec 2022, based on events up to Dec 5, 2022

1.1 Continued, Significant Growth in the T2D Market, With Drug Sales Expected to Almost Double Across the 9MM by the End of the Forecast Period

1.2 T2D Developers Battle for Share in an Increasingly Crowded Market

1.3 Decrease in Sales Among Branded T2D Drugs Across the 9MM

1.4 Glucagon-Like Peptide -1 Receptor Agonist Class Faces Intense Internal Competition, Largely Revolving Around Drugs’ Ability to Improve Patient Compliance/Ease of Administration and Reduced Risk of Major Adverse Cardiovascular Events

1.5 Label Expansions for SGLT-2 Inhibitors

1.6 What Do Physicians Think?

2 Introduction – Updated Dec 2022, based on events up to Dec 5, 2022

2.1 Catalyst

2.2 Related Reports

3 Disease Overview

3.1 Etiology

3.2 Pathophysiology

3.3 Symptoms

3.4 Prognosis and Quality of Life

4 Epidemiology

4.1 Disease Background

4.2 Risk Factors and Comorbidities

4.3 Global and Historical Trends

4.4 Forecast Methodology

4.4.1 Sources

4.4.2 Forecast Assumptions and Methods: Diagnosed Prevalent Cases of T2D

4.4.3 Forecast Assumptions and Methods: Prevalent Cases of CKD Among the Diagnosed Prevalent Cases of T2D

4.4.4 Forecast Assumptions and Methods: Prevalent Cases of CVD Among the Diagnosed Prevalent Cases of T2D

4.4.5 Forecast Assumptions and Methods: Prevalent Cases of Obesity Among the Diagnosed Prevalent Cases of T2D

4.4.6 Forecast Assumptions and Methods: Prevalent Cases of Hypertension Among the Diagnosed Prevalent Cases of T2D

4.4.7 Forecast Assumptions and Methods: Prevalent Cases of Dyslipidemia Among the Diagnosed Prevalent Cases of T2D

4.4.8 Forecast Assumptions and Methods: Prevalent Cases of Atherosclerosis Among the Diagnosed Prevalent Cases of T2D

4.5 Epidemiological Forecast for Type 2 Diabetes (2018–2028)

4.5.1 Diagnosed Prevalent Cases of T2D

4.5.2 Age-Specific Diagnosed Prevalent Cases of T2D

4.5.3 Sex-Specific Diagnosed Prevalent Cases of T2D

4.5.4 Comorbidities Among the Diagnosed Prevalent Cases of T2D

4.6 Discussion

4.6.1 Epidemiological Forecast Insight

4.6.2 Limitations of the Analysis

4.6.3 Strengths of the Analysis

5 Disease Management

5.1 Diagnosis and Treatment Overview

5.2 US

5.3 5EU

5.3.1 France

5.3.2 Germany

5.3.3 Italy

5.3.4 Spain

5.3.5 UK

5.4 Japan

5.5 China

5.6 India

6 Competitive Assessment – Updated Dec 2022, based on events up to Dec 5, 2022

6.1 Overview

7 Unmet Needs and Opportunities

7.1 Overview

7.2 Disease-Modifying Treatments Providing Sustained Glycemic Control

7.3 Drugs with Non-glycemic Benefits

7.4 Drugs with Improved Side-Effect Profiles

7.5 Increased Patient Compliance

7.6 Drugs for the Emergent T2D Pediatric Population

7.7 Controls on Insulin Drug Pricing and the Need for Fairly Priced Biologics

8 Pipeline Assessment – Updated Dec 2022, based on events up to Dec 5, 2022

8.1 Overview

8.2 Promising Drugs in Clinical Development

9 Current and Future Players – Updated Dec 2022, based on events up to Dec 5, 2022

9.1 Overview

9.2 Trends in Corporate Strategy

10 Market Outlook – Updated Dec 2022, based on events up to Dec 5, 2022

10.1 Global Markets

10.1.1 Forecast

10.1.2 Drivers and Barriers – Global Issues

10.2 US

10.2.1 Forecast

10.2.2 Key Events

10.2.3 Drivers and Barriers

10.3 5EU

10.3.1 Forecast

10.3.2 Key Events

10.3.3 Drivers and Barriers

10.4 Japan

10.4.1 Forecast

10.4.2 Key Events

10.4.3 Drivers and Barriers

10.5 China

10.5.1 Forecast

10.5.2 Key Events

10.5.3 Drivers and Barriers

10.6 India

10.6.1 Forecast

10.6.2 Key Events

10.6.3 Drivers and Barriers

11 Appendix

11.1 Abbreviations

11.2 Bibliography

11.3 Methodology

11.3.1 Forecasting Methodology

11.4 Physicians and Specialists Included in this Study

11.5 About the Authors

11.5.1 Healthcare Analyst

11.5.2 Therapy Area Director

11.5.3 Epidemiologists

11.5.4 Vice President of Disease Analysis and Intelligence

11.5.5 Global Head and EVP of Healthcare Operations and Strategy

| Contact Us

Table

Table 1: T2D: Key Metrics in the Nine Major Pharmaceutical Markets

Table 2: Primary Pathophysiologic Conditions Associated with T2D

Table 3: Symptoms of T2D presents an overview of the most frequently observed symptoms for T2D.

Table 4: Risk Factors and Comorbidities for T2D

Table 5: Diagnostic Tests and Typical Criteria for Diagnosing T2D

Table 6: Country Profile, T2D Management, US

Table 7: Country Profile, T2D Management, France

Table 8: Country Profile, T2D Management, Germany

Table 9: Absence of Typical T2D Symptoms, Italy

Table 10: Individuals with Increased Risk of T2D, Italy

Table 11: Country Profile, T2D Management, Italy

Table 12: Country Profile, T2D Management, Spain

Table 13: Country Profile, T2D Management, UK

Table 14: Country Profile, T2D Management, Japan

Table 15: Country Profile, T2D Management, China

Table 16: Country Profile, T2D Management, India

Table 17: Leading Branded Treatments for T2D, 2022

Table 18: T2D Market – Drivers and Barriers, 2020

Table 19: Key Events Impacting Sales for T2D in the US, 2019–2029

Table 20: T2D Market – Drivers and Barriers in the US, 2020

Table 21: Key Events Impacting Sales for T2D in the 5EU, 2019–2029

Table 22: T2D Market – Drivers and Barriers in the 5EU, 2020

Table 23: Key Events Impacting Sales for T2D in Japan, 2019–2029

Table 24: T2D Market – Drivers and Barriers in Japan, 2020

Table 25: Key Events Impacting Sales for T2D in China, 2019–2029

Table 26: T2D Market – Drivers and Barriers in China, 2020

Table 27: Key Events Impacting Sales for T2D in India, 2019–2029

Table 28: T2D Market – Drivers and Barriers in India, 2020

Table 29: Number of High-Prescribing Physicians Surveyed

Figures

Figure 1: Global Sales By Region (Type 2 Diabetes) 2019 and 2029

Figure 2: Company Portfolio Gap Analysis in T2D, 2019–2029

Figure 3: Competitive Assessment of Late-Stage (Phase III) Pipeline Agents in T2D, 2019–2029

Figure 4: T2D Pathophysiology

Figure 5: 9MM, Diagnosed Prevalence of T2D (%), Men, All Ages, 2018

Figure 6: 9MM, Diagnosed Prevalence of T2D (%), Women, All Ages, 2018

Figure 7: 9MM, Sources Used and Not Used to Forecast Diagnosed Prevalent Cases of T2D

Figure 8: 9MM, Sources Used to Forecast the Prevalent Cases of CKD Among the Diagnosed Prevalent Cases of T2D

Figure 9: 9MM, Sources Used to Forecast the Prevalent Cases of CVD Among the Diagnosed Prevalent Cases of T2D

Figure 10: 9MM, Sources Used to Forecast the Prevalent Cases of Obesity Among the Diagnosed Prevalent Cases of T2D

Figure 11: 9MM, Sources Used to Forecast the Prevalent Cases of Hypertension Among the Diagnosed Prevalent Cases of T2D

Figure 12: 9MM, Sources Used to Forecast the Prevalent Cases of Dyslipidemia Among the Diagnosed Prevalent Cases of T2D

Figure 13: 9MM, Sources Used to Forecast the Prevalent Cases of Atherosclerosis Among the Diagnosed Prevalent Cases of T2D

Figure 14: 9MM, Diagnosed Prevalent Cases of T2D, Both Sexes, All Ages, N, 2018

Figure 15: 9MM, Age-Specific Diagnosed Prevalent Cases of T2D, Both Sexes, N, 2018

Figure 16: 9MM, Sex-Specific Diagnosed Prevalent Cases of T2D, All Ages, N, 2018

Figure 17: 9MM, Prevalent Cases of CKD Among the Diagnosed Prevalent Cases of T2D, Both Sexes, All Ages, N, 2018

Figure 18: 9MM, Prevalent Cases of CVD Among the Diagnosed Prevalent Cases of T2D, Both Sexes, All Ages, N, 2018

Figure 19: 9MM, Prevalent Cases of Obesity Among the Diagnosed Prevalent Cases of T2D, Both Sexes, All Ages, N, 2018

Figure 20: 9MM, Prevalent Cases of Hypertension Among the Diagnosed Prevalent Cases of T2D, Both Sexes, All Ages, N, 2018

Figure 21: 9MM, Diagnosed Prevalent Cases of Dyslipidemia Among the Diagnosed Prevalent Cases of T2D, Both Sexes, All Ages, N, 2018

Figure 22: 9MM, Prevalent Cases of Atherosclerosis Among the Diagnosed Prevalent Cases of T2D, Both Sexes, All Ages, N, 2018

Figure 23: ADA Treatment Algorithm for Antihyperglycemic Therapy in T2D

Figure 24: Unmet Needs and Opportunities in T2D

Figure 25: Pipeline Agents in Development for T2D

Figure 26: Key Phase II/III Trials for the Promising Pipeline Agents That GlobalData Expects to be Licensed for T2D in the 9MM During the Forecast Period

Figure 27: Company Portfolio Gap Analysis in T2D, 2019–2029

Figure 28: Global Sales for T2D by Country/Region, 2019 and 2029

Figure 29: Sales for T2D in the US by Drug Class, 2019 and 2029

Figure 30: Sales for T2D in the 5EU by Drug Class, 2019 and 2029

Figure 31: Sales for T2D in Japan by Drug Class, 2019 and 2029

Figure 32: Sales for T2D in China by Drug Class, 2019 and 2029

Figure 33: Sales for T2D in India by Drug Class, 2019 and 2029

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