Biomarkers and Companion Diagnostics in Oncology
All the vital news, analysis, and commentary curated by our industry experts.
A biomarker is a defined molecular characteristic, for example a genetic mutation, that can tell a physician more about a patient’s disease state, or how they might respond to treatment. Predictive biomarkers indicate how likely a patient is to respond to a treatment, and are used in clinical decision making. In some cases, a patient must possess a particular biomarker to receive a particular drug. For example, breast cancer patients must test positive for HER2 in order to receive anti-HER2 therapy. Companion diagnostics (CDx) are in vitro diagnostics used to measure biomarkers deemed essential for the use of a particular drug, and their use is on the rise, particularly in oncology. In fact, over 90% of FDA-approved CDx are for cancer indications. This is likely because oncology treatments have a relatively high ‘failure’ rate compared to other diseases, and treating a patient with the right drug is often very time-sensitive due to the aggressive nature of some cancers. Biomarkers are of high interest to multiple stakeholders in oncology and have been a major focus of the major international medical congresses in recent years, reflecting the rapidly growing oncology CDx market.
In this report, GlobalData provides an overview of oncology-specific biomarkers and CDx in the 8MM (US, 5EU, Japan and China) including key opinion leader and payer perspectives throughout. Coverage includes insights into select biomarkers across seven oncology indications, CDx technologies, market access trends, market drivers, barriers and unmet needs, key products and companies, emerging areas of interest, and market outlook.
GlobalData’s Biomarkers and Companion Diagnostics in Oncology report combines primary research from key opinion leaders and payers with in-house analyst expertise to provide an assessment of the development landscape.
Components of the slide deck include primary and secondary research:
• Quotes from 7 US-, 5EU-, Japan- and China-based key opinion leaders and from 2 payers (EU and US)
• Provides an overview of biomarkers and CDx in the 8MM
• Explains the terminology surrounding CDx, which is still evolving across the 8MM and can have implications for how CDx are used and accessed
• Highlights the aspects of healthcare systems and national regulatory landscapes that are important in achieving market and patient access to CDx in the 8MM
• Identifies the market drivers, barriers and unmet needs in the global CDx market
• Provides an overview of the different types of CDx technologies and highlights which ones will drive market growth in the next five years
• Gives an overview of the main biomarkers currently used in clinical practice and in clinical trials
• Gives an overview of marketed and pipeline CDx products, and key pharma, biotech and diagnostic companies
• Provides detailed insights from leading physicians and payers and identifies emerging topics of interest within this field
• Insight from GlobalData’s specialist oncology analysts
Reasons to Buy
Develop business strategies by understanding the opportunities and challenges for biomarkers and CDx in the 8MM
Drive revenues through understanding the market trends and unmet needs in the global CDx market
Become acquainted with how CDx are regulated and reimbursed in the 8MM, and the associated opportunities and challenges
Understand the emerging technologies that are being used for CDx platforms and how these will drive market growth
Find out who the key CDx players are and the business models they use to achieve success in this growing market
Merck & Co.
Ventana Medical Systems
Table of Contents
1 Table of Contents (PowerPoint Deck)
1.1 Table of Contents
1.3 Related Reports
1.4 Upcoming Related Reports
2. Executive Summary
2.1 Key Findings
2.2 KOL and Payer Insights
3. Introduction to Biomarkers and Companion Diagnostics in Oncology
3.1 Biomarkers and Companion Diagnostics in the Era of Personalized Medicine
4. Companion Diagnostic Technologies
4.2 Nucleic Acid-Based Technologies
4.3 Protein-Based Technologies
4.4 Most Common Marketed Technologies
4.5 KOL Perspectives
5. Predictive Biomarkers in Oncology
5.2 Predictive Biomarkers in Breast Cancer
5.3 Predictive Biomarkers in Non-Small Cell Lung Cancer
5.4 Predictive Biomarkers in Melanoma
5.5 Predictive Biomarkers in Colorectal Cancer
5.6 Predictive Biomarkers in Ovarian Cancer
5.7 Predictive Biomarkers in Acute Myeloid Leukemia
5.8 Predictive Biomarkers in Site-Agnostic Cancers
6. Emerging Areas of Interest
6.2 Trial Design Disruption
6.3 Liquid Biopsies
6.4 Biomarkers for CAR-T Cell Therapy
7. Market Opportunities
7.2 Market Drivers
7.3 Market Barriers
7.4 Unmet Needs
8. Market Access
8.2 Global Regulatory Agencies’ Definitions of CDx
8.3 Regulation and Reimbursement in the US
8.4 Regulation and Reimbursement in the EU
8.5 Regulation and Reimbursement in Japan
8.6 Regulation and Reimbursement in China
9. Companion Diagnostic Products and Key Players
9.2 Key Players in the US CDx Market
9.3 Key Players in the Japan CDx Market
9.4 Key Player Company Profiles
9.5 CDx Business Models and Key Players
9.6 Marketed Product Examples
9.7 Pipeline Overview
10. Market Outlook
10.1 Expert Perspectives
11.1 Marketed CDx
11.2 Pipeline CDx
11.4 Primary Research
11.5 About the Authors
11.6 About GlobalData
11.7 Contact Us
Frequently asked questions
Tel +44 20 7947 2745
Every customer’s requirement is unique. With over 220,000 construction projects tracked, we can create a tailored dataset for you based on the types of projects you are looking for. Please get in touch with your specific requirements and we can send you a quote.
Business Intelligence & Marketing Manager, SAL Heavy Lift
“The GlobalData platform is our go-to tool for intelligence services. GlobalData provides an easy way to access comprehensive intelligence data around multiple sectors, which essentially makes it a one-for-all intelligence platform, for tendering and approaching customers.
GlobalData is very customer orientated, with a high degree of personalised services, which benefits everyday use. The highly detailed project intelligence and forecast reports can be utilised across multiple departments and workflow scopes, from operational to strategic level, and often support strategic decisions. GlobalData Analytics and visualisation solutions has contributed positively when preparing management presentations and strategic papers.”
Market Analyst & Management, Liebherr-Werk
“COVID-19 has caused significant interference to our business and the COVID-19 intelligence from GlobalData has helped us reach better decisions around strategy. These two highlights have helped enormously to understand the projections into the future concerning our business units, we also utilise the project database to source new projects for Liebherr-Werk to use as an additional source to pitch for new business.”
Head of Key Accounts, Saab AB
Your daily news has saved me a lot of time and keeps me up-to-date with what is happening in the market, I like that you almost always have a link to the source origin. We also use your market data in our Strategic Business Process to support our business decisions. By having everything in one place on the Intelligence Center it has saved me a lot of time versus looking on different sources, the alert function also helps with this.
Marketing Intelligence Manager, Portugal Foods
Having used several other market research companies, I find that GlobalData manages to provide that ‘difficult-to-get’ market data that others can’t, as well as very diverse and complete consumer surveys.
Head of Customer Insight and Research, Standard Chartered
Our experience with GlobalData has been very good, from the platform itself to the people. I find that the analysts and the account team have a high level of customer focus and responsiveness and therefore I can always rely on. The platform is more holistic than other providers. It is convenient and almost like a one stop shop. The pricing suite is highly competitive and value for our organisation.
I like reports that inform new segments such as the analysis on generation Z, millennials, the impact of COVID 19 to our banking customers and their new channel habits. Secondly the specialist insight on affluent sector significantly increases our understanding about this group of customers. The combination of those give us depth and breadth of the evolving market.
I’m in the business of answering and helping people make decisions so with the intelligence center I can do that, effectively and efficiently. I can share quickly key insights that answer and satisfy our country stakeholders by giving them many quality studies and primary research about competitive landscape beyond the outlook of our bank. It helps me be seen as an advisory partner and that makes a big difference. A big benefit of our subscription is that no one holds the whole data and because it allows so many people, so many different parts of our organisation have access, it enables all teams to have the same level of knowledge and decision support.
Head of Consumer Sensory Insights, Givaudan
“I know that I can always rely on Globaldata’s work when I’m searching for the right consumer and market insights. I use Globaldata insights to understand the changing market & consumer landscape and help create better taste & wellbeing solutions for our customers in food, beverage and healthcare industries.
Globaldata has the right data and the reports are of very high quality compared to your competitors. Globaldata not only has overall market sizes & consumer insights on food & beverages but also provides insights at the ingredient & flavour level. That is key for B2B companies like Givaudan. This way we understand our customers’ business and also gain insight to our unique industry”
Senior Account Manager, TSYS
GlobalData provides a great range of information and reports on various sectors that is highly relevant, timely, easy to access and utilise. The reports and data dashboards help engagement with clients; they provide valuable industry and market insights that can enrich client conversations and can help in the shaping of value propositions. Moreover, using GlobalData products has helped increase my knowledge of the finance sector, the players within it, and the general threats and opportunities.
I find the consumer surveys that are carried out to be extremely beneficial and not something I have seen anywhere else. They provided an insightful view of why and which consumers take (or don’t) particular financial products. This can help shape conversations with clients to ensure they make the right strategic decisions for their business.
One of the challenges I have found is that data in the payments space is often piecemeal. With GD all of the data I need is in one place, but it also comes with additional market reports that provide useful extra context and information. Having the ability to set-up alerts on relevant movements in the industry, be it competitors or customers, and have them emailed directly to me, ensures I get early sight of industry activity and don’t have to search for news.