Myelofibrosis – Drugs In Development, 2024

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Published: June 05, 2024 Report Code: GDGMDHC23114IDB-L5

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Myelofibrosis is a rare bone marrow disorder where abnormal cells cause fibrous tissue buildup, impairing blood cell production. It’s a type of myeloproliferative neoplasm, leading to an enlarged spleen, anemia, fatigue, and increased infection risk. JAK2, MPL, or CALR mutations often underlie this condition. Diagnosis involves blood tests, bone marrow biopsy, and imaging. Treatment aims to manage symptoms and might involve medications, blood transfusions, targeted therapies, or stem cell transplantation in severe cases. Myelofibrosis is chronic and variable; management focuses on improving quality of life and addressing complications through personalized approaches and regular monitoring.

The Myelofibrosis drugs in development market research report provide comprehensive information on the therapeutics under development for Myelofibrosis, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action and product description of the therapeutics, and the latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Myelofibrosis and features dormant and discontinued products.

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* This is an “on-demand” report and will be delivered within 2 business days (excluding weekends and holidays) of the purchase.

* Certain sections in the report may be removed or altered based on the availability and relevance of data.

Quick View – Myelofibrosis
Key Targets
· Tyrosine Protein Kinase JAK2; Tyrosine Protein Kinase JAK1; Bromodomain Containing Protein 4; Transforming Growth Factor Beta 1 Proprotein; Receptor Type Tyrosine Protein Kinase FLT3; Phosphatidylinositol 4,5 Bisphosphate 3 Kinase Catalytic Subunit Delta Isoform; Bromodomain Containing Protein 2; Apoptosis Regulator Bcl 2; Bromodomain Containing Protein 3; and Bromodomain Containing Protein
Key Mechanisms of Action
· Tyrosine Protein Kinase JAK2 Inhibitor; Tyrosine Protein Kinase JAK1 Inhibitor; Bromodomain Containing Protein 4 Inhibitor; Transforming Growth Factor Beta 1 Proprotein Inhibitor; Receptor Type Tyrosine Protein Kinase FLT3 Inhibitor; Phosphatidylinositol 4,5 Bisphosphate 3 Kinase Catalytic Subunit Delta Isoform Inhibitor; Bromodomain Containing Protein 2 Inhibitor; Bromodomain Containing Protein 3 Inhibitor; Apoptosis Regulator Bcl 2 Inhibitor; and Bromodomain Containing Protein Inhibitor
Key Routes of Administration
· Oral; Intravenous; Subcutaneous; Topical; Intramuscular; Inhalational; and Ophthalmic
Key Molecule Types
· Small Molecule; Monoclonal Antibody; Cell Therapy; Fusion Protein; Recombinant Vector Vaccine; Subunit Vaccine; Antibody; Recombinant Protein; Oligonucleotide; and Monoclonal Antibody Conjugated
Major Companies
· Incyte Corp; Novartis AG; AbbVie Inc; Bristol-Myers Squibb Co; Cellenkos Inc; Chia Tai Tianqing Pharmaceutical Group Co Ltd; Lotus Pharmaceutical Co Ltd; Merck & Co Inc; Johnson & Johnson; and H. Lee Moffitt Cancer Center & Research Institute Inc

Scope

  • Therapeutics in Development: Covering 90 molecules, with 85 developed by companies and the rest by universities/institutes.

  • Analysis Parameters: Offering insights by stage of development, drug target, MoA, RoA, and molecule type for a comprehensive overview.

  • Pharmacological Insights: Understand the descriptive pharmacological action of therapeutics.

  • Development History: Access the complete research and development history.

  • Latest News and Press Releases: Stay updated with the latest developments through comprehensive news coverage.

Reasons to Buy

  • Holistic insights: Understand the broad spectrum of Myelofibrosis therapeutics, aiding strategic decision-making with insights into stages, targets, MoA, RoA and molecule types.

  • Pipeline Exploration: Explore the detailed Myelofibrosis pipeline, offering nuanced analysis of drug targets, mechanisms of action and routes of administration for varied decision-making.

  • Comprehensive R&D: Access thorough R&D histories, providing a comprehensive understanding of Myelofibrosis treatments for adaptable decision-making.

  • Save valuable hours: Identify key players steering innovation in therapeutics, enabling strategic partnerships.

Key Players

AbbVie Inc
Abfero Pharmaceuticals Inc
Active Biotech AB
Actuate Therapeutics Inc
Ajax Therapeutics Inc
Antengene Corp Ltd
AOP Health
Aviceda Therapeutics Inc
Bayer AG
Biolexis Therapeutics Inc
Boston University School of Medicine
Bristol-Myers Squibb Co
Cellenkos Inc
Chengdu Jinrui Foundation Biotechnology Co Ltd
Chengdu Zenitar Biomedical Technology Co Ltd
Chia Tai Tianqing Pharmaceutical Group Co Ltd
CTI BioPharma Corp
Cyclica Inc
Disc Medicine Inc
Galecto Inc
GAT Therapeutics SL
Geron Corp
GSK plc
H. Lee Moffitt Cancer Center & Research Institute Inc
Hangzhou East China Pharmaceutical Group Co Ltd
Helocyte Biosciences Inc
Hinova Pharmaceuticals Co Ltd
Imago BioSciences Inc
Incyte Corp
IO Biotech Inc
iOnctura SA
Italfarmaco SpA
Jacobio Pharmaceuticals Group Co Ltd
Johnson & Johnson
JW Pharmaceutical Corp
Kartos Therapeutics Inc
Karyopharm Therapeutics Inc
Keros Therapeutics Inc
Lotus Pharmaceutical Co Ltd
Lympharma LLC
MEI Pharma Inc
Merck & Co Inc
Millennium Pharmaceuticals Inc
Morphic Therapeutic Inc
MorphoSys AG
Newave Pharmaceutical Inc
Novartis AG
NS Pharma Inc
Opna Bio SA
Orca Biosystems Inc
Pfizer Inc
PharmaEssentia Corp
Pharmaxis Ltd
Plexium Inc
Prelude Therapeutics Inc
Rhizen Pharmaceuticals SA
Ryvu Therapeutics SA
Samus Therapeutics Inc
Scholar Rock Inc
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd
Shenyang Pharmaceutical University
Shouyao Holding Co Ltd
Sino Biopharmaceutical Ltd
Stemline Therapeutics Inc
Sumitomo Dainippon Pharma Oncology
Inc
Suzhou Zelgen Biopharmaceutical Co Ltd
Telios Pharma Inc
TG Therapeutics Inc
University of Texas MD Anderson Cancer Center
Wigen Biomedicine Technology (Shanghai) Co Ltd

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Overview

Therapeutics Development

Pipeline Overview

Pipeline by Companies

Pipeline by Universities/Institutes

Drugs Under Development by Companies

Drugs under Development by Universities/Institutes

Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Companies Involved in Therapeutic Development

Drug Profiles

Dormant Projects

Discontinued Drugs

Product Development Milestones

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Drugs under Development, 2024

Number of Drugs under Development by Companies, 2024

Number of Drugs under Development by Universities/Institutes, 2024

Drugs under Development by Companies, 2024

Drugs under Development by Universities/Institutes, 2024

Number of Drugs by Stage and Target, 2024

Number of Drugs by Stage and Mechanism of Action, 2024

Number of Drugs by Stage and Route of Administration, 2024

Number of Drugs by Stage and Molecule Type, 2024

Dormant Projects, 2024

Discontinued Drugs, 2024

Figures

List of Figures

Number of Drugs under Development, 2024

Number of Drugs under Development by Companies, 2024

Number of Drugs under Development by Universities/Institutes, 2024

Number of Drugs by Top 10 Targets, 2024

Number of Drugs by Stage and Top 10 Targets, 2024

Number of Drugs by Top 10 Mechanism of Actions, 2024

Number of Drugs by Stage and Top 10 Mechanism of Actions, 2024

Number of Drugs by Top 10 Routes of Administration, 2024

Number of Drugs by Stage and Top 10 Routes of Administration, 2024

Number of Drugs by Top 10 Molecule Types, 2024

Number of Drugs by Stage and Top 10 Molecule Types, 2024

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