Lupus Nephritis – Drugs In Development, 2024

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Lupus nephritis is a severe complication of systemic lupus erythematosus (SLE), an autoimmune disease that affects various organs, tissues, and systems within the body. Lupus nephritis specifically involves inflammation of the kidneys, leading to kidney damage and impaired kidney function.

In systSLE, the body’s immune system mistakenly attacks its own tissues and organs, including the kidneys, causing inflammation. Not all individuals with SLE develop lupus nephritis, but it can significantly impact those who do.

Symptoms of lupus nephritis can vary widely, ranging from mild to severe, and can include high blood pressure; swelling, particularly in the legs, feet, hands, or face; dark urine or blood in the urine; proteinuria (excessive protein in the urine); reduced urine output; fatigue; and general discomfort.

The Lupus Nephritis drugs in development market research report provide comprehensive information on the therapeutics under development for Lupus Nephritis, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action and product description of the therapeutics, and the latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Lupus Nephritis and features dormant and discontinued products.

Note:

* This is an “on-demand” report and will be delivered within 2 business days (excluding weekends and holidays) of the purchase.

* Certain sections in the report may be removed or altered based on the availability and relevance of data.

Quick View – Lupus Nephritis
Key Targets
· B Lymphocyte Antigen CD19; B Lymphocyte Antigen CD20; Complement C5; Mannan Binding Lectin Serine Protease 2; Inosine Monophosphate Dehydrogenase; Serine/Threonine Protein Kinase Pim 2; Serine/Threonine Protein Kinase Pim 3; ADP Ribosyl Cyclase/Cyclic ADP Ribose Hydrolase 1; Complement Factor B; and Interleukin 17A
Key Mechanisms of Action
· Complement C5 Inhibitor; B Lymphocyte Antigen CD20 Inhibitor; Mannan Binding Lectin Serine Protease 2 Inhibitor; Interleukin 17A Inhibitor; Inosine Monophosphate Dehydrogenase Inhibitor; IgG Receptor FcRn Large Subunit p51 Antagonist; ADP Ribosyl Cyclase/Cyclic ADP Ribose Hydrolase 1 Inhibitor; Complement Factor B Inhibitor; Serine/Threonine Protein Kinase Pim 1 Inhibitor; and Serine/Threonine Protein Kinase Pim 2 Inhibitor
Key Routes of Administration
· Intravenous; Subcutaneous; Oral; Parenteral; Intravenous Drip; Intralesional; Intravitreal; and Ophthalmic
Key Molecule Types
· Monoclonal Antibody; Small Molecule; Gene-Modified Cell Therapy; Fusion Protein; Cell Therapy; Recombinant Protein; Synthetic Peptide; Oligonucleotide; Biologic; and Antisense RNAi Oligonucleotide
Major Companies
· Novartis AG; Johnson & Johnson; F. Hoffmann-La Roche Ltd; Kyverna Therapeutics Inc; Alexion Pharmaceuticals Inc; Resolve Therapeutics LLC; Transcenta Holding Ltd; UCB SA; University of Southern California; and Slate Bio Inc

Scope

  • Therapeutics in Development: Covering 70 molecules, with 68 developed by companies and the rest by universities/institutes.
  • Analysis Parameters: Offering insights by stage of development, drug target, MoA, RoA, and molecule type for a comprehensive overview.
  • Pharmacological Insights: Understand the descriptive pharmacological action of therapeutics.
  • Development History: Access the complete research and development history.
  • Latest News and Press Releases: Stay updated with the latest developments through comprehensive news coverage.

Reasons to Buy

  • Holistic insights: Understand the broad spectrum of Lupus Nephritis therapeutics, aiding strategic decision-making with insights into stages, targets, MoA, RoA and molecule types.
  • Pipeline Exploration: Explore the detailed Lupus Nephritis pipeline, offering nuanced analysis of drug targets, mechanisms of action and routes of administration for varied decision-making.
  • Comprehensive R&D: Access thorough R&D histories, providing a comprehensive understanding of Lupus Nephritis treatments for adaptable decision-making.
  • Save valuable hours: Identify key players steering innovation in therapeutics, enabling strategic partnerships.

Key Players

149 Bio LLC
AbbVie Inc
Alexion Pharmaceuticals Inc
Alphamab Oncology
Alpine Immune Sciences Inc
Amgen Inc
Annexon Inc
Apellis Pharmaceuticals Inc
Aria Pharmaceuticals Inc
Asahi Kasei Pharma Corp
AstraZeneca Plc
Astria Therapeutics Inc
BeiGene Ltd
Beijing Mabworks Biotech Co Ltd
Bellvitge Biomedical Research Institute
BioAegis Therapeutics Inc
Biocon Ltd
Bristol-Myers Squibb Co
Cabaletta Bio Inc
Capricor Therapeutics Inc
Cellenkos Inc
Chinook Therapeutics Inc
Chugai Pharmaceutical Co Ltd
Corestemchemon Inc
Createrna Science and Technology Co Ltd
Eledon Pharmaceuticals Inc
Equillium Inc
Everest Medicines Ltd
F. Hoffmann-La Roche Ltd
Genrix (Shanghai) Biopharmaceutical Co Ltd
Horizon Therapeutics Plc
ImmPACT Bio USA Inc
ImmuneID Inc
Inflection Biosciences Ltd
Innovent Biologics Inc
Jiangsu Hengrui Medicine Co Ltd
JiangSu Qyuns Therapeutics Co Ltd
Jiangsu Ruiyuan Biotechnology Co Ltd
Johnson & Johnson
Juventas Cell Therapy Ltd
Kezar Life Sciences Inc
Kyverna Therapeutics Inc
Lepton Pharmaceuticals Ltd
MorphoSys AG
Mysthera Therapeutics AG
Neutrolis Inc
Nkarta Inc
Novartis AG
NovelMed Therapeutics Inc
Omeros Corp
Orbsen Therapeutics Ltd
Pfizer Inc
Ra Pharmaceuticals Inc
RemeGen Co Ltd
Resolve Therapeutics LLC
Sana Biotechnology Inc
SciRhom GmbH
Serenity Bioworks Inc
Slate Bio Inc
Transcenta Holding Ltd
UCB SA
University of Southern California
Zai Lab Ltd

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Overview

Therapeutics Development

Pipeline Overview

Pipeline by Companies

Pipeline by Universities/Institutes

Drugs Under Development by Companies

Drugs under Development by Universities/Institutes

Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Companies Involved in Therapeutic Development

Drug Profiles

Dormant Projects

Discontinued Drugs

Product Development Milestones

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Drugs under Development, 2024

Number of Drugs under Development by Companies, 2024

Number of Drugs under Development by Universities/Institutes, 2024

Drugs under Development by Companies, 2024

Drugs under Development by Universities/Institutes, 2024

Number of Drugs by Stage and Target, 2024

Number of Drugs by Stage and Mechanism of Action, 2024

Number of Drugs by Stage and Route of Administration, 2024

Number of Drugs by Stage and Molecule Type, 2024

Dormant Projects, 2024

Discontinued Drugs, 2024

Figures

List of Figures

Number of Drugs under Development, 2024

Number of Drugs under Development by Companies, 2024

Number of Drugs under Development by Universities/Institutes, 2024

Number of Drugs by Top 10 Targets, 2024

Number of Drugs by Stage and Top 10 Targets, 2024

Number of Drugs by Top 10 Mechanism of Actions, 2024

Number of Drugs by Stage and Top 10 Mechanism of Actions, 2024

Number of Drugs by Top 10 Routes of Administration, 2024

Number of Drugs by Stage and Top 10 Routes of Administration, 2024

Number of Drugs by Top 10 Molecule Types, 2024

Number of Drugs by Stage and Top 10 Molecule Types, 2024

Frequently asked questions

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