Amyloidosis Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

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Amyloidosis Pipeline Drugs Market Overview

Abnormal accumulation of amyloid protein in the tissues results in a group of diseases known as amyloidosis. It may affect the shape and functioning of the organ eventually leading to organ failure. Predisposing factors are misfolding of an abnormal protein called the light chain and its subsequent deposition in the body. It may also occur because of dialysis. Symptoms include fatigue, chest pain, swelling, and breathing problems. Amyloidosis can be managed by transplant and, medication such as diuretics and chemotherapy drugs.

The Amyloidosis drugs in development market research report provide comprehensive information on the therapeutics under development for Amyloidosis, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history, and the latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Amyloidosis and features dormant and discontinued projects.

Key Targets in the Amyloidosis Pipeline Products Market

The key targets in the Amyloidosis pipeline products market are Transthyretin, Cells Expressing ADP Ribosyl Cyclase/Cyclic ADP Ribose Hydrolase 1, Amyloid Protein And Peptide, Alpha Synuclein, Amyloid Beta A4 Protein, Interleukin 1 Beta, Microtubule Associated Protein Tau, B Cell Lymphoma 2, Cells Expressing Tumor Necrosis Factor Receptor Superfamily Member 17, 20s Proteasome, and others.

Amyloidosis Pipeline Products Analysis Market by Targets

Amyloidosis Pipeline Products Analysis Market by Targets

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Key Mechanisms of Action in the Amyloidosis Pipeline Products Market

The key mechanisms of action in the Amyloidosis pipeline products market are Transthyretin Inhibitor, Cytotoxic To Cells Expressing ADP Ribosyl Cyclase/Cyclic ADP Ribose Hydrolase 1, Amyloid Protein And Peptide Inhibitor, Transthyretin Activator, Alpha Synuclein Inhibitor, Amyloid Beta A4 Protein Inhibitor, Interleukin 1 Beta Inhibitor, Microtubule Associated Protein Tau Inhibitor, B Cell Lymphoma 2 Inhibitor, Cytotoxic To Cells Expressing Tumor Necrosis Factor Receptor Superfamily Member 17, and others.

Amyloidosis Pipeline Products Market Analysis by Mechanism of Actions

Amyloidosis Pipeline Products Market Analysis by Mechanism of Actions

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Key Routes of Administration in the Amyloidosis Pipeline Products Market

The key routes of administration in the Amyloidosis pipeline products market are intravenous, subcutaneous, oral, parenteral, and topical.

Amyloidosis Pipeline Products Market Analysis by Routes of Administration

Amyloidosis Pipeline Products Market Analysis by Routes of Administration

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Key Molecule Types in the Amyloidosis Pipeline Products Market

The key molecule types in the Amyloidosis pipeline products market are small molecule, monoclonal antibody, fusion protein, antisense RNAi oligonucleotide, gene therapy, Antisense Oligonucleotide, Gene-Modified Cell Therapy, Monoclonal Antibody Conjugated, recombinant peptide, antibody, and others.

Amyloidosis Pipeline Products Market Analysis by Molecule Type

Amyloidosis Pipeline Products Market Analysis by Molecule Type

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Major Companies in the Amyloidosis Pipeline Products Market

Some of the major companies in the Amyloidosis pipeline products market are Alnylam Pharmaceuticals Inc, Akcea Therapeutics Inc, Attralus Inc, Johnson & Johnson, Alexion Pharmaceuticals Inc, Autotac Bio Inc, BridgeBio Pharma Inc, BSIM Therapeutics SA, Millennium Pharmaceuticals Inc, and Proclara Biosciences Inc.

Amyloidosis Pipeline Products Market Analysis by Companies

Amyloidosis Pipeline Products Market Analysis by Companies

To know more about major companies, download a free report sample

Market Report Overview

Key targets Transthyretin Inhibitor, Cytotoxic To Cells Expressing ADP Ribosyl Cyclase/Cyclic ADP Ribose Hydrolase 1, Amyloid Protein And Peptide Inhibitor, Transthyretin Activator, Alpha Synuclein Inhibitor, Amyloid Beta A4 Protein Inhibitor, Interleukin 1 Beta Inhibitor, Microtubule Associated Protein Tau Inhibitor, B Cell Lymphoma 2 Inhibitor, Cytotoxic To Cells Expressing Tumor Necrosis Factor Receptor Superfamily Member 17, and Others
Key mechanism of action Transthyretin Inhibitor, Cytotoxic To Cells Expressing ADP Ribosyl Cyclase/Cyclic ADP Ribose Hydrolase 1, Amyloid Protein And Peptide Inhibitor, Transthyretin Activator, Alpha Synuclein Inhibitor, Amyloid Beta A4 Protein Inhibitor, Interleukin 1 Beta Inhibitor, Microtubule Associated Protein Tau Inhibitor, B Cell Lymphoma 2 Inhibitor, Cytotoxic To Cells Expressing Tumor Necrosis Factor Receptor Superfamily Member 17, and others
Key routes of administration Intravenous, Subcutaneous, Oral, Parenteral, and Topical
Key molecule type Small Molecule, Monoclonal Antibody, Fusion Protein, Antisense RNAi Oligonucleotide, Gene Therapy, Antisense Oligonucleotide, Gene-Modified Cell Therapy, Monoclonal Antibody Conjugated, Recombinant Peptide, Antibody, and Others
Major companies Alnylam Pharmaceuticals Inc, Akcea Therapeutics Inc, Attralus Inc, Johnson & Johnson, Alexion Pharmaceuticals Inc, Autotac Bio Inc, BridgeBio Pharma Inc, BSIM Therapeutics SA, Millennium Pharmaceuticals Inc, and Proclara Biosciences Inc

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of Amyloidosis (Metabolic Disorders).
  • The pipeline guide reviews pipeline therapeutics for Amyloidosis (Metabolic Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Amyloidosis (Metabolic Disorders) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Amyloidosis (Metabolic Disorders) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA), and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews the latest news related to pipeline therapeutics for Amyloidosis (Metabolic Disorders)

Reasons to Buy

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Amyloidosis (Metabolic Disorders).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and their most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Amyloidosis (Metabolic Disorders) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from the pipeline.

3SBio Inc
AbbVie Inc
ADRx Inc
Akcea Therapeutics Inc
Alexion Pharmaceuticals Inc
Alnylam Pharmaceuticals Inc
Amgen Inc
Amyl Therapeutics
Attralus Inc
Autotac Bio Inc
Auven Therapeutics Development Switzerland Sarl
BridgeBio Pharma Inc
Bristol-Myers Squibb Co
Brooklyn ImmunoTherapeutics Inc
BSIM Therapeutics SA
Chugai Pharmaceutical Co Ltd
Corino Therapeutics Inc
Covalent Bioscience Inc
Dren Bio Inc
EUSA Pharma (UK) Ltd
GlaxoSmithKline Plc
Guangdong Yinzhu Pharmaceutical Technology Co Ltd
HaemaLogix Pty Ltd
IMMvention Therapeutix Inc
Johnson & Johnson
Karyopharm Therapeutics Inc
Mabpharm Ltd
Millennium Pharmaceuticals Inc
Mitsubishi Tanabe Pharma Corp
Novo Nordisk AS
Precision Biosciences Inc
Proclara Biosciences Inc
Prothena Corp Plc
R-Pharm
Regeneron Pharmaceuticals Inc
ResQ Biotech
Sanofi
Shanghai YaKe Biotechnology Co Ltd
SOLA Biosciences LLC
Sorrento Therapeutics Inc
Spectrum Pharmaceuticals Inc
Telix Pharmaceuticals Ltd
Vera Therapeutics Inc
Zentalis Pharmaceuticals Inc

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Amyloidosis – Overview

Amyloidosis – Therapeutics Development

Pipeline Overview

Pipeline by Companies

Pipeline by Universities/Institutes

Products under Development by Companies

Products under Development by Universities/Institutes

Amyloidosis – Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Amyloidosis – Companies Involved in Therapeutics Development

Amyloidosis – Drug Profiles

Amyloidosis – Dormant Projects

Amyloidosis – Discontinued Products

Amyloidosis – Product Development Milestones

Featured News & Press Releases

Feb 17, 2022: Intellia Therapeutics announces two upcoming investor events in February 2022

Jan 24, 2022: Eplontersen granted Orphan Drug Designation in the US for transthyretin amyloidosis

Jan 21, 2022: Alnylam presents positive 18-Month results from HELIOS-A phase 3 study of investigational Vutrisiran in patients with hATTR amyloidosis with polyneuropathy

Jan 14, 2022: Alnylam to present full 18-month results from the HELIOS-A phase 3 study of vutrisiran at the Société Francophone du Nerf Périphérique Annual Meeting

Dec 27, 2021: BridgeBio Pharma reports month 12 topline results from phase 3 ATTRibute-CM study

Dec 27, 2021: BridgeBio Pharma reports month 12 topline results from phase 3 ATTRibute-CM study

Dec 13, 2021: Attralus presents positive new data at 2021 American Society of Hematology Annual Meeting

Nov 22, 2021: Intellia Therapeutics announces expansion of ongoing phase 1 study of NTLA-2001 to include adults with transthyretin amyloidosis with cardiomyopathy (ATTR-CM)

Nov 22, 2021: Intellia Therapeutics announces expansion of ongoing phase 1 study of NTLA-2001 to include adults with transthyretin amyloidosis with cardiomyopathy (ATTR-CM)

Nov 04, 2021: Attralus to present new data at 2021 American Society of Hematology Annual Meeting

Oct 27, 2021: Alnylam reports positive topline 18-month results from HELIOS-A phase 3 study of Vutrisiran in patients with hATTR amyloidosis with polyneuropathy

Oct 27, 2021: Alnylam reports positive topline 18-month results from HELIOS-A phase 3 study of Vutrisiran in patients with hATTR amyloidosis with polyneuropathy

Oct 21, 2021: Intellia Therapeutics receives U.S. FDA Orphan Drug Designation for NTLA-2001, an investigational CRISPR therapy for the treatment of transthyretin (ATTR) amyloidosis

Oct 11, 2021: Tegsedi receives innovative drug category pricing in Brazil

Sep 13, 2021: Alnylam submits marketing authorization application to the European Medicines Agency for investigational vutrisiran for the treatment of hereditary ATTR amyloidosis with polyneuropathy

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Products under Development for Amyloidosis, 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Companies, 2022 (Contd..1)

Number of Products under Development by Universities/Institutes, 2022

Products under Development by Companies, 2022

Products under Development by Companies, 2022 (Contd..1)

Products under Development by Companies, 2022 (Contd..2)

Products under Development by Companies, 2022 (Contd..3)

Products under Development by Companies, 2022 (Contd..4)

Products under Development by Universities/Institutes, 2022

Number of Products by Stage and Target, 2022

Number of Products by Stage and Mechanism of Action, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Amyloidosis – Pipeline by 3SBio Inc, 2022

Amyloidosis – Pipeline by AbbVie Inc, 2022

Amyloidosis – Pipeline by ADRx Inc, 2022

Amyloidosis – Pipeline by Akcea Therapeutics Inc, 2022

Amyloidosis – Pipeline by Alexion Pharmaceuticals Inc, 2022

Amyloidosis – Pipeline by Alnylam Pharmaceuticals Inc, 2022

Amyloidosis – Pipeline by Amgen Inc, 2022

Amyloidosis – Pipeline by Amyl Therapeutics, 2022

Amyloidosis – Pipeline by Attralus Inc, 2022

Amyloidosis – Pipeline by Autotac Bio Inc, 2022

Amyloidosis – Pipeline by Auven Therapeutics Development Switzerland Sarl, 2022

Amyloidosis – Pipeline by BridgeBio Pharma Inc, 2022

Amyloidosis – Pipeline by Bristol-Myers Squibb Co, 2022

Amyloidosis – Pipeline by Brooklyn ImmunoTherapeutics Inc, 2022

Amyloidosis – Pipeline by BSIM Therapeutics SA, 2022

Amyloidosis – Pipeline by Chugai Pharmaceutical Co Ltd, 2022

Amyloidosis – Pipeline by Corino Therapeutics Inc, 2022

Amyloidosis – Pipeline by Covalent Bioscience Inc, 2022

Amyloidosis – Pipeline by Dren Bio Inc, 2022

Amyloidosis – Pipeline by EUSA Pharma (UK) Ltd, 2022

Amyloidosis – Pipeline by GlaxoSmithKline Plc, 2022

Amyloidosis – Pipeline by Guangdong Yinzhu Pharmaceutical Technology Co Ltd, 2022

Amyloidosis – Pipeline by HaemaLogix Pty Ltd, 2022

Amyloidosis – Pipeline by IMMvention Therapeutix Inc, 2022

Amyloidosis – Pipeline by Johnson & Johnson, 2022

Amyloidosis – Pipeline by Karyopharm Therapeutics Inc, 2022

Amyloidosis – Pipeline by Mabpharm Ltd, 2022

Amyloidosis – Pipeline by Millennium Pharmaceuticals Inc, 2022

Amyloidosis – Pipeline by Mitsubishi Tanabe Pharma Corp, 2022

Amyloidosis – Pipeline by Novo Nordisk AS, 2022

Amyloidosis – Pipeline by Precision Biosciences Inc, 2022

Amyloidosis – Pipeline by Proclara Biosciences Inc, 2022

Amyloidosis – Pipeline by Prothena Corp Plc, 2022

Amyloidosis – Pipeline by R-Pharm, 2022

Amyloidosis – Pipeline by Regeneron Pharmaceuticals Inc, 2022

Amyloidosis – Pipeline by ResQ Biotech, 2022

Amyloidosis – Pipeline by Sanofi, 2022

Amyloidosis – Pipeline by Shanghai YaKe Biotechnology Co Ltd, 2022

Amyloidosis – Pipeline by SOLA Biosciences LLC, 2022

Amyloidosis – Pipeline by Sorrento Therapeutics Inc, 2022

Amyloidosis – Pipeline by Spectrum Pharmaceuticals Inc, 2022

Amyloidosis – Pipeline by Telix Pharmaceuticals Ltd, 2022

Amyloidosis – Pipeline by Vera Therapeutics Inc, 2022

Amyloidosis – Pipeline by Zentalis Pharmaceuticals Inc, 2022

Amyloidosis – Dormant Projects, 2022

Amyloidosis – Dormant Projects, 2022 (Contd..1)

Amyloidosis – Discontinued Products, 2022

Figures

List of Figures

Number of Products under Development for Amyloidosis, 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Universities/Institutes, 2022

Number of Products by Top 10 Targets, 2022

Number of Products by Stage and Top 10 Targets, 2022

Number of Products by Top 10 Mechanism of Actions, 2022

Number of Products by Stage and Top 10 Mechanism of Actions, 2022

Number of Products by Routes of Administration, 2022

Number of Products by Stage and Routes of Administration, 2022

Number of Products by Molecule Types, 2022

Number of Products by Stage and Molecule Types, 2022

Frequently asked questions

  • What are the key targets in the Amyloidosis pipeline products market?

    The key targets in the Amyloidosis pipeline products market are Transthyretin, Cells Expressing ADP Ribosyl Cyclase/Cyclic ADP Ribose Hydrolase 1, Amyloid Protein And Peptide, Alpha Synuclein, Amyloid Beta A4 Protein, Interleukin 1 Beta, Microtubule Associated Protein Tau, B Cell Lymphoma 2, Cells Expressing Tumor Necrosis Factor Receptor Superfamily Member 17, 20s Proteasome, and others.

  • What are the key mechanisms of action in the Amyloidosis pipeline products market?

    The key mechanisms of action in the Amyloidosis pipeline products market are Transthyretin Inhibitor, Cytotoxic To Cells Expressing ADP Ribosyl Cyclase/Cyclic ADP Ribose Hydrolase 1, Amyloid Protein And Peptide Inhibitor, Transthyretin Activator, Alpha Synuclein Inhibitor, Amyloid Beta A4 Protein Inhibitor, Interleukin 1 Beta Inhibitor, Microtubule Associated Protein Tau Inhibitor, B Cell Lymphoma 2 Inhibitor, Cytotoxic To Cells Expressing Tumor Necrosis Factor Receptor Superfamily Member 17, and others.

  • What are the key routes of administration in the Amyloidosis pipeline products market?

    The key routes of administration in the Amyloidosis pipeline products market are intravenous, subcutaneous, oral, parenteral, and topical.

  • What are the key molecule types in the Amyloidosis pipeline products market?

    The key molecule types in the Amyloidosis pipeline products market are small molecule, monoclonal antibody, fusion protein, antisense RNAi oligonucleotide, gene therapy, antisense oligonucleotide, gene-modified cell therapy, monoclonal antibody conjugated, recombinant peptide, antibody, and others.

  • Which are the major companies in the Amyloidosis pipeline products market?

    Some of the major companies in the Amyloidosis pipeline products market are Alnylam Pharmaceuticals Inc, Akcea Therapeutics Inc, Attralus Inc, Johnson & Johnson, Alexion Pharmaceuticals Inc, Autotac Bio Inc, BridgeBio Pharma Inc, BSIM Therapeutics SA, Millennium Pharmaceuticals Inc, and Proclara Biosciences Inc.

Amyloidosis Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update standard reports
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