B-Cell Non-Hodgkin Lymphoma (NHL) Marketed and Pipeline Drugs Assessment, Clinical Trials and Competitive Landscape

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B-Cell Non-Hodgkin Lymphoma (NHL) Marketed and Pipeline Drugs Market Report Overview

B-cell NHL generally arises in the lymphoid tissue, such as the lymph nodes, bone marrow, thymus, and spleen, and can disseminate to involve distant sites such as the lung or brain in the later stages of the disease. NHLs are further categorized into indolent or aggressive prognostic subtypes, which further influence outcomes and treatment decisions.

The B-Cell NHL marketed, and pipeline drugs market research report includes an assessment of the disease epidemiology, leading marketed products with sales forecast, pricing and reimbursement, late-to-mid-stage pipeline products with phase transition success rate (PTSR), and the likelihood of approval (LoA) for B-cell NHL. The report also analyzes the clinical and commercial landscapes of B-cell NHL, as well as an assessment of deals, future market catalysts, key market players, and the future competitive environment.

Leading Marketed Drugs in B-Cell NHL

A few of the leading marketed drugs in B-Cell NHL are polatuzumab vedotin, Zanubrutinib, Pembrolizumab, and interferon alfa among others. Most marketed drugs for B-cell NHL belong to the class of enzyme inhibitors and protein/peptide inhibitors targeting kinases and proteins like programmed cell death protein 1.

B-Cell NHL Marketed and Pipeline Drugs Market - Top Clinical Trial Sponsors

A few of the top clinical trial sponsors in the B-Cell NHL marketed and pipeline drugs market are F.Hoffmann-La Roche Ltd, University of Texas MD Anderson Cancer Center, National Cancer Institute US, Johnson & Johnson, Gilead Sciences Inc, Celgene Corp, BeiGene Ltd, Novartis AG, and AbbVie Inc among others.

B-Cell NHL Marketed and Pipeline Drugs Market Sponsor Analysis

B-Cell NHL Marketed and Pipeline Drugs Market Sponsor Analysis

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B-Cell NHL Marketed Drugs Segmentation by Mechanism of Action

Some of the key mechanisms of action for B-Cell NHL marketed drugs are peptide and peptide inhibitor, genes, nucleic acids & related component inhibitor, protein and peptide activator, enzyme inhibitor, cytotoxic cell, receptor agonist, and receptor antagonist. The peptide and peptide inhibitor segment was the most common mechanism of action for B-Cell NHL marketed drugs.

B-Cell NHL Marketed Drugs Analysis, by Mechanism of Action

B-Cell NHL Marketed Drugs Analysis, by Mechanism of Action

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B-Cell NHL Marketed Drugs Segmentation by Routes of Administration

The key routes of administration for B-Cell NHL marketed drugs are injection, oral, topical, and suppository.  Most conventional marketed drugs available for B-Cell NHL are intravenous therapies.

B-Cell NHL Marketed Drugs Analysis, by Routes of Administration

B-Cell NHL Marketed Drugs Analysis, by Routes of Administration

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B-Cell NHL Marketed Drugs Segmentation by Molecule Type

The key molecule types in the market are small molecule and biologics. The marketed drugs space for B-Cell NHL is dominated by the small molecule segment.

B-Cell NHL Marketed Drugs Analysis, by Molecule Type

B-Cell NHL Marketed Drugs Analysis, by Molecule Type

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B-Cell NHL Pipeline Drugs Segmentation by Mechanism of Action

A few of the key mechanisms of action for B-Cell NHL pipeline drugs are cytotoxic to cell, enzyme inhibitor, protein and peptide inhibitor, receptor agonist, receptor antagonist, and antigen inhibitor among others. Cytotoxic to cell lead the MoA segment in the B-Cell NHL pipeline drugs market.

B-Cell NHL Pipeline Drugs Analysis, by Mechanisms of Action

B-Cell NHL Pipeline Drugs Analysis, by Mechanisms of Action

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B-Cell NHL Pipeline Drugs Segmentation by Routes of Administration

The key routes of administration for B-Cell NHL pipeline drugs are injection, oral, topical, inhalational, and suppository. Most pipeline drugs for B-cell NHL are injection therapies followed by oral drugs.

B-Cell NHL Pipeline Drugs Analysis, by Routes of Administration

B-Cell NHL Pipeline Drugs Analysis, by Routes of Administration

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B-Cell NHL Pipeline Drugs Segmentation by Molecule Type

The B-Cell NHL pipeline drugs comprise mostly biologics, small molecules, and oligonucleotide. Most More than 60% of the B-cell NHL pipeline is dominated by biologic molecules.

B-Cell NHL Pipeline Drugs Analysis, by Molecule Types

B-Cell NHL Pipeline Drugs Analysis, by Molecule Types

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B-Cell NHL Marketed and Pipeline Drugs – Deals Landscape

  • On 8th Dec 2022, Actinium pharma enters into research agreement with Columbia university.
  • On 21 Nov 2022, Opna bio acquires oncology assets from Plexxikon.

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Key Mechanisms of Action (Marketed) ·        Peptide and Peptide Inhibitor

·        Genes, Nucleic Acids & Related Component Inhibitor

·        Protein and Peptide Activator

·        Enzyme Inhibitor

·        Cytotoxic Cell

·        Receptor Agonist

·        Receptor Antagonist.

Key Routes of Administration (Marketed) ·        Injection

·        Oral

·        Topical

·        Suppository

Key Molecule Types (Marketed) ·        Small Molecule

·        Biologics

Key Mechanisms of Action (Pipeline) ·        Cytotoxic to Cell

·        Enzyme Inhibitor

·        Protein and Peptide Inhibitor

·        Receptor Agonist

·        Receptor Antagonist

·        Antigen Inhibitor

Key Routes of Administration (Pipeline) ·        Injection

·        Oral

·        Topical

·        Inhalational

·        Suppository

Key Molecule Types (Pipeline) ·        Biologics

·        Small Molecule

·        Oligonucleotide

Top Clinical Trial Sponsors ·        F.Hoffmann-La Roche Ltd

·        University of Texas MD Anderson Cancer Center

·        National Cancer Institute US

·        Johnson & Johnson

·        Gilead Sciences Inc

·        Celgene Corp

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Segments Covered in the Report

B-Cell NHL Marketed Drugs MoA Outlook

  • Peptide and Peptide Inhibitor
  • Genes, Nucleic Acids & Related Component Inhibitor
  • Protein and Peptide Activator
  • Enzyme Inhibitor
  • Cytotoxic Cell
  • Receptor Agonist
  • Receptor Antagonist.

B-Cell NHL Marketed Drugs RoA Outlook

  • Injection
  • Oral
  • Topical
  • Suppository

B-Cell NHL Marketed Drugs Molecule Type Outlook

  • Small Molecule
  • Biologics

B-Cell NHL Pipeline Drugs MoA Outlook

  • Cytotoxic to Cell
  • Enzyme Inhibitor
  • Protein and Peptide Inhibitor
  • Receptor Agonist
  • Receptor Antagonist
  • Antigen Inhibitor

B-Cell NHL Pipeline Drugs RoA Outlook

  • Injection
  • Oral
  • Topical
  • Inhalational
  • Suppository

B-Cell NHL Pipeline Drugs Molecule Type Outlook

  • Biologics
  • Small Molecule
  • Oligonucleotide

Scope

GlobalData’s B-Cell NHL Marketed and Pipeline Drugs Assessment, Clinical Trials, and Competitive Landscape combine data from the Pharma Intelligence Center with in-house analyst expertise to provide a competitive assessment of the disease marketplace.

Components of the report include:

  • Disease Landscape
  • Disease Overview
  • Epidemiology Overview
  • Treatment Overview
  • Marketed Products Assessment
  • Breakdown by Mechanism of Action, Molecule Type, Route of Administration
  • Product Profiles with Sales Forecast
  • Pricing and Reimbursement Assessment
  • Retail or Manufacturer Price of Products
  • Time to Pricing and Time to Reimbursement
  • Pipeline Assessment
  • Breakdown by Development Stage, Mechanism of Action, Molecule Type, Route of Administration
  • Product Profiles with Sales Forecast
  • Late-to-mid-stage Pipeline Drugs
  • Phase Transition Success Rate and Likelihood of Approval
  • Clinical Trials Assessment
  • Breakdown of Trials by Phase, Status, Virtual Components, Sponsors, Geography, and Endpoint Status
  • Enrolment Analytics, Site Analytics, Feasibility Analysis
  • Deals Landscape
  • Mergers, Acquisitions, and Strategic Alliances by Region
  • Overview of Recent Deals
  • Commercial Assessment
  • Key Market Players
  • Future Market Catalysts

Reasons to Buy

  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the B-Cell NHL market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global B-Cell NHL market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and strategic partnerships.

Key Players

Table of Contents

1 Preface

1.1 Contents

1.2 Report Scope

1.3 List of Tables and Figures

1.4 Abbreviations

2 Key Findings

3 Disease Landscape

3.1 Disease Overview

3.2 Epidemiology Overview

3.3 Treatment Overview

4 Marketed Drugs Assessment

4.1 Leading Marketed Drugs

4.2 Overview by Mechanism of Action

4.3 Overview by Route of Administration

4.4 Marketed Drugs Profiles and Sales Forecasts

5 Pricing and Reimbursement Assessment

5.1 Manufacturer Price

5.2 Time to Pricing and Reimbursement

6 Pipeline Drugs Assessment

6.1 Phase III Pipeline Drugs

6.2 Overview by Development Stage

6.3 Overview by Molecule Type

6.4 Overview by Mechanism of Action

6.5 Overview by Route of Administration

6.6 Drug Specific Phase Transition Success Rate (PTSR) and Likelihood of Approval (LoA)

6.7 Therapy Area and Indication-specific PTSR and LoA

7 Clinical Trials Assessment

7.1 Historical Overview

7.2 Overview by Phase

7.3 Overview by Status

7.4 Overview by Phase for Ongoing and Planned Trials

7.5 Trials with Virtual Components

7.6 Geographic Overview

7.7 Single-Country and Multinational Trials by Region

7.8 Top 20 Sponsors with Breakdown by Phase

7.9 Top 20 Sponsors with Breakdown by Status

7.10 Overview by Endpoint Status

7.11 Overview by Race and Ethnicity

7.12 Enrollment Data

7.13 Top 20 countries for Trial Sites

7.14 Top 20 Sites Globally

7.15 Feasibility Analysis – Geographic Overview

7.16 Feasibility Analysis – Benchmark Models

8 Deals Landscape

8.1 Mergers, Acquisitions, and Strategic Alliances by Region

8.2 Recent Mergers, Acquisitions, and Strategic Alliances

9 Commercial Assessment

9.1 Key Market Players

10 Future Market Catalysts

11 Appendix

11.1 Methodology

11.2 Methodology – Sales Forecast

11.3 Methodology – Pricing and Reimbursement

11.4 Methodology – PTSR and LoA Analysis

11.5 About the Authors

11.6 Contact Us

11.7 Disclaimer

Frequently asked questions

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