Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

Powered by

All the vital news, analysis, and commentary curated by our industry experts.

Fibrodysplasia Ossificans Progressiva Pipeline Drugs Market

Fibrodysplasia ossificans progressiva (FOP) is a disorder in which muscle tissue and connective tissue such as tendons and ligaments are gradually replaced by bone (ossified), forming bone outside that constrains movement. Symptoms swellings in fibrous tissue, pain, fever, muscle ossification, and restricted movement of joints. Treatment includes surgery and medications to help relieve symptoms of FOP, such as pain and inflammation.

The FOP pipeline products market research report provides comprehensive information on the therapeutics under development for FOP, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history, and the latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for FOP and features dormant and discontinued projects.

FOP Pipeline Products Market Segmentation by Targets

The key targets in the FOP pipeline products market are Activin Receptor Type 1, Retinoic Acid Receptor Gamma, Growth/Differentiation Factor 8, Inhibin Beta A Chain, Proto Oncogene Tyrosine Protein Kinase Src, Serine/Threonine Protein Kinase mTOR, Tyrosine Protein Kinase ABL1, and Tyrosine Protein Kinase Fyn. Activin Receptor Type 1 is the leading target in the FOP pipeline products market.

FOP Pipeline Products Market Analysis by Targets

FOP Pipeline Products Market Analysis by Targets

For more target insights into the FOP pipeline products market, download a free report sample

FOP Pipeline Products Market Segmentation by Mechanisms of Action

The key mechanisms of action in the FOP pipeline products market are Activin Receptor Type 1 Inhibitor, Retinoic Acid Receptor Gamma Agonist, Activin Receptor Type 1 Antagonist, Growth/Differentiation Factor 8 Inhibitor, Inhibin Beta A Chain Inhibitor, Proto Oncogene Tyrosine Protein Kinase Src Inhibitor, Serine/Threonine Protein Kinase mTOR Inhibitor, Tyrosine Protein Kinase ABL1 Inhibitor, and Tyrosine Protein Kinase Fyn Inhibitor. Activin Receptor Type 1 Inhibitor is the leading MoA in the pipeline market.

FOP Pipeline Products Market Analysis by Mechanisms of Action

FOP Pipeline Products Market Analysis by Mechanisms of Action

For more MoA insights into the FOP pipeline products market, download a free report sample

FOP Pipeline Products Market Segmentation by Routes of Administration

The key routes of administration in the FOP pipeline products market are oral, ophthalmic, subcutaneous, intravenous, and topical. Oral accounted for the highest number of FOP drugs in development in terms of RoA, in 2022.

FOP Pipeline Products Market Analysis by Routes of Administration

FOP Pipeline Products Market Analysis by Routes of Administration

For more RoA insights into the FOP pipeline products market, download a free report sample

FOP Pipeline Products Market Segmentation by Molecule Types

The key molecule types in the FOP pipeline products market are small molecule, monoclonal antibody, and antibody. The small molecule is the leading molecule type in the FOP pipeline drugs market.

FOP Pipeline Products Market Analysis by Molecule Types

FOP Pipeline Products Market Analysis by Molecule Types

For more molecule type insights into the FOP pipeline products market, download a free report sample

FOP Pipeline Products Market - Competitive Landscape

Some of the leading companies in the FOP pipeline products market are Regeneron Pharmaceuticals Inc, Ipsen SA, La Jolla Pharmaceutical Company, AstraZeneca Plc, Clementia Pharmaceuticals Inc, Daiichi Sankyo Co Ltd, Incyte Corp, and Pfizer Inc. Regeneron Pharmaceuticals Inc is the leading company in the FOP pipeline products market.

FOP Pipeline Products Market Analysis by Companies

FOP Pipeline Products Market Analysis by Companies

To know more about the leading FOP pipeline products market players, download a free report sample

FOP Pipeline Products Market Overview

Key Targets Activin Receptor Type 1, Retinoic Acid Receptor Gamma, Growth/Differentiation Factor 8, Inhibin Beta A Chain, Proto Oncogene Tyrosine Protein Kinase Src, Serine/Threonine Protein Kinase mTOR, Tyrosine Protein Kinase ABL1, and Tyrosine Protein Kinase Fyn
Key MoA Activin Receptor Type 1 Inhibitor, Retinoic Acid Receptor Gamma Agonist, Activin Receptor Type 1 Antagonist, Growth/Differentiation Factor 8 Inhibitor, Inhibin Beta A Chain Inhibitor, Proto Oncogene Tyrosine Protein Kinase Src Inhibitor, Serine/Threonine Protein Kinase mTOR Inhibitor, Tyrosine Protein Kinase ABL1 Inhibitor, and Tyrosine Protein Kinase Fyn Inhibitor
Key RoA Oral, Ophthalmic, Subcutaneous, Intravenous, and Topical
Key Molecule Type Small Molecule, Monoclonal Antibody, and Antibody
Leading Companies Regeneron Pharmaceuticals Inc, Ipsen SA, La Jolla Pharmaceutical Company, AstraZeneca Plc, Clementia Pharmaceuticals Inc, Daiichi Sankyo Co Ltd, Incyte Corp, and Pfizer Inc

Scope

  • The pipeline guide provides a snapshot of the global therapeutic landscape of FOP.
  • The pipeline guide reviews pipeline therapeutics for FOP by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration to discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in FOP therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates FOP therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA), and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews the latest news related to pipeline therapeutics for FOP

Reasons to Buy

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolios and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for FOP.
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and their most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding the FOP pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from the pipeline.

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Overview

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Therapeutics Development

Pipeline Overview

Pipeline by Companies

Pipeline by Universities/Institutes

Products under Development by Companies

Products under Development by Universities/Institutes

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Companies Involved in Therapeutics Development

AstraZeneca Plc

Clementia Pharmaceuticals Inc

Daiichi Sankyo Co Ltd

Incyte Corp

Ipsen SA

La Jolla Pharmaceutical Company

Pfizer Inc

Regeneron Pharmaceuticals Inc

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Drug Profiles

dipyridamole – Drug Profile

Product Description

Mechanism Of Action

DS-6016 – Drug Profile

Product Description

Mechanism Of Action

garetosmab – Drug Profile

Product Description

Mechanism Of Action

INCB-00928 – Drug Profile

Product Description

Mechanism Of Action

IPN-60130 – Drug Profile

Product Description

Mechanism Of Action

palovarotene – Drug Profile

Product Description

Mechanism Of Action

saracatinib difumarate – Drug Profile

Product Description

Mechanism Of Action

sirolimus – Drug Profile

Product Description

Mechanism Of Action

Small Molecule 1 To Inhibit ALK2 for Fibrodysplasia Ossificans Progressiva – Drug Profile

Product Description

Mechanism Of Action

Small Molecule 2 To Inhibit ALK2 for Fibrodysplasia Ossificans Progressiva – Drug Profile

Product Description

Mechanism Of Action

Small Molecule for Fibrodysplasia Ossificans Progressiva – Drug Profile

Product Description

Mechanism Of Action

Small Molecule to Inhibit ALK2 for Fibrodysplasia Ossificans Progressiva – Drug Profile

Product Description

Mechanism Of Action

trevogrumab – Drug Profile

Product Description

Mechanism Of Action

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Dormant Projects

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Discontinued Products

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Product Development Milestones

Featured News & Press Releases

Oct 25, 2022: Ipsen statement on updated timeline for palovarotene FDA Advisory Committee meeting

Jun 29, 2022: Ipsen announces U.S. FDA priority review for palovarotene new drug application in patients with fibrodysplasia ossificans progressiva following resubmission

Jan 24, 2022: Health Canada approves Ipsen’s Sohonos (palovarotene capsules) as the first approved treatment for Fibrodysplasia Ossificans Progressiva

Aug 13, 2021: Ipsen announces withdrawal of palovarotene NDA, confirming intention to re-submit following additional data analyses

May 28, 2021: Ipsen confirms U.S. FDA accepts new drug application for Palovarotene as the first potential treatment worldwide for fibrodysplasia ossificans progressiva (FOP)

Oct 30, 2020: Regeneron provides update on the Garetosmab phase 2 LUMINA-1 trial in fibrodysplasia ossificans progressiva (FOP)

Sep 10, 2020: Ipsen to present new Insights at ASBMR for potential treatment of ultra-rare disease Fibrodysplasia Ossificans Progressiva (FOP), including global phase III MOVE Trial results

Aug 25, 2020: Ipsen to present results from MOVE, the first global phase III trial in fibrodysplasia ossificans progressiva (FOP), at ASBMR 2020 annual meeting

Mar 27, 2020: Ipsen to restart dosing of palovarotene in FOP studies

Jan 27, 2020: Ipsen temporarily stops palovarotene dosing in FOP trials

Jan 10, 2020: Regeneron reports positive data from rare bone disease trials

Jan 09, 2020: Regeneron announces encouraging garetosmab phase 2 results in patients with ultra-rare debilitating bone disease

Dec 09, 2019: Ipsen initiates partial clinical hold for palovarotene IND120181 and IND135403 studies

Mar 27, 2019: Blueprint Medicines provides update on clinical progress of BLU-782

Feb 11, 2019: Clementia granted Rare Pediatric Disease Designation by FDA for Palovarotene for Fibrodysplasia Ossificans Progressiva

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Products under Development for Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva), 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Universities/Institutes, 2022

Products under Development by Companies, 2022

Products under Development by Companies, 2022 (Contd..1)

Products under Development by Universities/Institutes, 2022

Number of Products by Stage and Target, 2022

Number of Products by Stage and Mechanism of Action, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Pipeline by AstraZeneca Plc, 2022

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Pipeline by Clementia Pharmaceuticals Inc, 2022

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Pipeline by Daiichi Sankyo Co Ltd, 2022

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Pipeline by Incyte Corp, 2022

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Pipeline by Ipsen SA, 2022

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Pipeline by La Jolla Pharmaceutical Company, 2022

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Pipeline by Pfizer Inc, 2022

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Pipeline by Regeneron Pharmaceuticals Inc, 2022

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Dormant Projects, 2022

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) – Discontinued Products, 2022

Figures

List of Figures

Number of Products under Development for Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva), 2022

Number of Products under Development by Companies, 2022

Number of Products by Top 10 Targets, 2022

Number of Products by Stage and Top 10 Targets, 2022

Number of Products by Top 10 Mechanism of Actions, 2022

Number of Products by Stage and Top 10 Mechanism of Actions, 2022

Number of Products by Top 10 Routes of Administration, 2022

Number of Products by Stage and Top 10 Routes of Administration, 2022

Number of Products by Top 10 Molecule Types, 2022

Number of Products by Stage and Top 10 Molecule Types, 2022

Frequently asked questions

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update standard reports
Currency USD
$2,000

Can be used by individual purchaser only

$6,000

Can be shared globally by unlimited users within the purchasing corporation e.g. all employees of a single company


Undecided about purchasing this report?

Enquire Before Buying Download FREE Resources

Get in touch to find out about multi-purchase discounts

reportstore@globaldata.com
Tel +44 20 7947 2745

Sample Report

Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update was curated by the best experts in the industry and we are confident about its unique quality. However, we want you to make the most beneficial decision for your business, so we offer free sample pages to help you:

  • Assess the relevance of the report
  • Evaluate the quality of the report
  • Justify the cost

Download your copy of the sample report and make an informed decision about whether the full report will provide you with the insights and information you need.

Below is a sample report to understand what you are buying

See what our customers are saying
testimonial-image
testimonial-image
testimonial-image
testimonial-image
testimonial-image
testimonial-image
testimonial-image

“The GlobalData platform is our go-to tool for intelligence services. GlobalData provides an easy way to access comprehensive intelligence data around multiple sectors, which essentially makes it a one-for-all intelligence platform, for tendering and approaching customers.

GlobalData is very customer orientated, with a high degree of personalised services, which benefits everyday use. The highly detailed project intelligence and forecast reports can be utilised across multiple departments and workflow scopes, from operational to strategic level, and often support strategic decisions. GlobalData Analytics and visualisation solutions has contributed positively when preparing management presentations and strategic papers.”

Business Intelligence & Marketing Manager, SAL Heavy Lift

“COVID-19 has caused significant interference to our business and the COVID-19 intelligence from GlobalData has helped us reach better decisions around strategy. These two highlights have helped enormously to understand the projections into the future concerning our business units, we also utilise the project database to source new projects for Liebherr-Werk to use as an additional source to pitch for new business.”

Market Analyst & Management, Liebherr-Werk

Your daily news has saved me a lot of time and keeps me up-to-date with what is happening in the market, I like that you almost always have a link to the source origin. We also use your market data in our Strategic Business Process to support our business decisions. By having everything in one place on the Intelligence Center it has saved me a lot of time versus looking on different sources, the alert function also helps with this.

Head of Key Accounts, Saab AB

Having used several other market research companies, I find that GlobalData manages to provide that ‘difficult-to-get’ market data that others can’t, as well as very diverse and complete consumer surveys.

Marketing Intelligence Manager, Portugal Foods

Our experience with GlobalData has been very good, from the platform itself to the people. I find that the analysts and the account team have a high level of customer focus and responsiveness and therefore I can always rely on. The platform is more holistic than other providers. It is convenient and almost like a one stop shop. The pricing suite is highly competitive and value for our organisation.

I like reports that inform new segments such as the analysis on generation Z, millennials, the impact of COVID 19 to our banking customers and their new channel habits. Secondly the specialist insight on affluent sector significantly increases our understanding about this group of customers. The combination of those give us depth and breadth of the evolving market.

I’m in the business of answering and helping people make decisions so with the intelligence center I can do that, effectively and efficiently. I can share quickly key insights that answer and satisfy our country stakeholders by giving them many quality studies and primary research about competitive landscape beyond the outlook of our bank. It helps me be seen as an advisory partner and that makes a big difference. A big benefit of our subscription is that no one holds the whole data and because it allows so many people, so many different parts of our organisation have access, it enables all teams to have the same level of knowledge and decision support.

Head of Customer Insight and Research, Standard Chartered

“I know that I can always rely on Globaldata’s work when I’m searching for the right consumer and market insights. I use Globaldata insights to understand the changing market & consumer landscape and help create better taste & wellbeing solutions for our customers in food, beverage and healthcare industries.

Globaldata has the right data and the reports are of very high quality compared to your competitors. Globaldata not only has overall market sizes & consumer insights on food & beverages but also provides insights at the ingredient & flavour level. That is key for B2B companies like Givaudan. This way we understand our customers’ business and also gain insight to our unique industry”

Head of Consumer Sensory Insights, Givaudan

GlobalData provides a great range of information and reports on various sectors that is highly relevant, timely, easy to access and utilise.  The reports and data dashboards help engagement with clients; they provide valuable industry and market insights that can enrich client conversations and can help in the shaping of value propositions. Moreover, using GlobalData products has helped increase my knowledge of the finance sector, the players within it, and the general threats and opportunities.

I find the consumer surveys that are carried out to be extremely beneficial and not something I have seen anywhere else. They provided an insightful view of why and which consumers take (or don’t) particular financial products. This can help shape conversations with clients to ensure they make the right strategic decisions for their business.

One of the challenges I have found is that data in the payments space is often piecemeal. With GD all of the data I need is in one place, but it also comes with additional market reports that provide useful extra context and information. Having the ability to set-up alerts on relevant movements in the industry, be it competitors or customers, and have them emailed directly to me, ensures I get early sight of industry activity and don’t have to search for news.

Senior Account Manager, TSYS
Go even deeper with GlobalData Intelligence Center

Every Company Report we produce is powered by the GlobalData Intelligence Center.

Subscribing to our intelligence platform means you can monitor developments at Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update in real time.

  • Access a live Fibrodysplasia Ossificans Progressiva (Myositis Ossificans Progressiva) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update dashboard for 12 months, with up-to-the-minute insights.
  • Fuel your decision making with real-time deal coverage and media activity.
  • Turn insights on financials, deals, products and pipelines into powerful agents of commercial advantage.