Hypercholesterolemia – Drugs In Development, 2024

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Hypercholesterolemia is a condition characterized by very high levels of cholesterol in the blood. This leads to the formation of sticky deposits (called plaque) along the artery walls. Plaque can completely block blood flow through an artery, causing a heart attack or stroke. Two forms of the condition exist: heterozygous familial hypercholesterolemia (HeFH) and homozygous familial hypercholesterolemia (HoFH). Risk factors include obesity, family history, high blood pressure, smoking, and diabetes. Treatment includes statins, bile acid sequestrants, fibric acid derivatives, and cholesterol absorption inhibitors.

The Hypercholesterolemia drugs in development market research report provide comprehensive information on the therapeutics under development for Hypercholesterolemia, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action and product description of the therapeutics, and the latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Hypercholesterolemia and features dormant and discontinued products.

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* This is an “on-demand” report and will be delivered within 2 business days (excluding weekends and holidays) of the purchase.

* Certain sections in the report may be removed or altered based on the availability and relevance of data.

Quick View – Hypercholesterolemia
Key Targets
· Proprotein Convertase Subtilisin/Kexin Type 9; 3 Hydroxy 3 Methylglutaryl Coenzyme A Reductase; Angiopoietin Related Protein 3; NPC1 Like Intracellular Cholesterol Transporter 1; Apolipoprotein C III; ATP Citrate Synthase; Cholesteryl Ester Transfer Protein; Thyroid Hormone Receptor Beta; Squalene Synthase; and Low Density Lipoprotein Receptor
Key Mechanisms of Action
· Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor; 3 Hydroxy 3 Methylglutaryl Coenzyme A Reductase Inhibitor; Angiopoietin Related Protein 3 Inhibitor; NPC1 Like Intracellular Cholesterol Transporter 1 Inhibitor; Apolipoprotein C III Inhibitor; ATP Citrate Synthase Inhibitor; Cholesteryl Ester Transfer Protein Inhibitor; Squalene Synthase Inhibitor; Thyroid Hormone Receptor Beta Agonist; and Thyroid Hormone Receptor Agonist
Key Routes of Administration
· Oral; Subcutaneous; Intravenous; Buccal; Intramuscular; Intraperitoneal; Nasal; Parenteral; Sublingual; and Topical
Key Molecule Types
· Small Molecule; Monoclonal Antibody; Gene Therapy; Antisense RNAi Oligonucleotide; Antisense Oligonucleotide; Synthetic Peptide; Biologic; Peptide; Fusion Protein; and Conjugate Vaccine
Major Companies
· Verve Therapeutics Inc; Arrowhead Pharmaceuticals Inc; Huons Co Ltd; iMetabolic Biopharma Corp; Nyrada Inc; NewAmsterdam Pharma Company NV; Medlab Clinical Ltd; LipimetiX Development Inc; Imagine Pharma LLC; and Ionis Pharmaceuticals Inc

Scope

  • Therapeutics in Development: Covering 130 molecules, with 118 developed by companies and the rest by universities/institutes.
  • Analysis Parameters: Offering insights by stage of development, drug target, MoA, RoA, and molecule type for a comprehensive overview.
  • Pharmacological Insights: Understand the descriptive pharmacological action of therapeutics.
  • Development History: Access the complete research and development history.
  • Latest News and Press Releases: Stay updated with the latest developments through comprehensive news coverage.

Reasons to Buy

  • Holistic insights: Understand the broad spectrum of Hypercholesterolemia therapeutics, aiding strategic decision-making with insights into stages, targets, MoA, RoA and molecule types.
  • Pipeline Exploration: Explore the detailed Hypercholesterolemia pipeline, offering nuanced analysis of drug targets, mechanisms of action and routes of administration for varied decision-making.
  • Comprehensive R&D: Access thorough R&D histories, providing a comprehensive understanding of Hypercholesterolemia treatments for adaptable decision-making.
  • Save valuable hours: Identify key players steering innovation in therapeutics, enabling strategic partnerships.

Key Players

Addpharma Inc
AFFiRiS AG
Ahn-Gook Pharmaceutical Co Ltd
Akeso Inc
Alexion Pharmaceuticals Inc
Amgen Inc
Amytrx Therapeutics Inc
Arrowhead Pharmaceuticals Inc
Astellas Pharma Inc
AstraZeneca Plc
Beijing Mabworks Biotech Co Ltd
BioLingus AG
Bojiyuan (Shanghai) Biopharmaceutical Co Ltd
Boryung Pharmaceutical Co Ltd
CardioPharma Inc
Celltrion Inc
Centeer BioTherapeutics Ltd Co
Chiesi Farmaceutici SpA
Cholesgen Shanghai Co Ltd
Chong Kun Dang Pharmaceutical Corp.
Civi Biopharma Inc
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co Ltd
Daewon Pharmaceutical Co Ltd
Daewoong Pharmaceutical Co Ltd
Dalian Wista Pharmaceutical Co Ltd
Delivra Corp
Draupnir Bio Aps
EDIRNA Inc
Eight Plus One Pharmaceutical Co Ltd
EmendoBio Inc
Epicrispr Biotechnologies Inc
Esperion Therapeutics Inc
Federal University of Rio de Janeiro
Golden Biotechnology Corp
Gruthan Bioscience LLC
Guangzhou Jiayue Pharmaceutical Technology Co Ltd
Haisco Pharmaceutical Group Co Ltd
Hanmi Pharmaceuticals Co Ltd
Hanmi Science Co Ltd
Hasten Biopharmaceutic Co Ltd
Hingez Therapeutics Inc
Huons Co Ltd
Ikaria Bioscience Pty Ltd
Imagine Pharma LLC
iMetabolic Biopharma Corp
Innovent Biologics Inc
Ionis Pharmaceuticals Inc
Jiangsu Carephar Pharmaceutical Co Ltd
Jiangsu Hengrui Medicine Co Ltd
JW Pharmaceutical Corp
Kowa Co Ltd
Kyttaro Ltd
LIB Therapeutics LLC
Lipigon Pharmaceuticals AB
LipimetiX Development Inc
Luckwel Pharmaceuticals Inc
Luye Pharma Group Ltd
Lyndra Therapeutics Inc.
MediciNova Inc
Medlab Clinical Ltd
Merck & Co Inc
Nanjing University of Science and Technology
NeuroBo Pharmaceuticals Inc
NewAmsterdam Pharma Company NV
NorthSea Therapeutics BV
Novartis AG
Novo Nordisk AS
NVP Healthcare Co Ltd
Nyrada Inc
OliPass Corporation
OrsoBio Inc
Otsuka Pharmaceutical Co Ltd
PRD Therapeutics Inc
Precision Biosciences Inc
Progenra Inc
Repair Biotechnologies Inc
Saliogen Therapeutics Inc
San Raffaele Telethon Institute for Gene Therapy
Sanegene Bio USA Inc
Sanofi
Seed Health Inc
Shandong Boan Biotechnology Co Ltd
Shanghai Henlius Biotech Inc
Shanghai Junshi Biosciences Co Ltd
Shenzhen Salubris Pharmaceuticals Co Ltd
Shifa Biomedical Corp
Sirius Therapeutics Inc
Sun Yat-sen University
Suzhou Ribo Life Sciences Co Ltd
Tangdu Hospital
Tasly Pharmaceutical Group Co Ltd
UAB Minority Health and Health Equity Research Center
Ultragenyx Pharmaceutical Inc
University Hospitals Leuven
University of Hong Kong
University of Montreal
University of Oxford
Vaxxinity Inc
Verve Therapeutics Inc
Vesicle Therapeutics Inc
Viking Therapeutics Inc
Viscera Labs Inc
Visirna Therapeutics HK Ltd
Wake Forest University
Xi'an Jiaotong University
Yaotang (Shanghai) Biotechnology Co Ltd
Zhejiang Jingxin Pharmaceutical Co Ltd
Zhejiang Teruisi Pharmaceutical Co Ltd

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Overview

Therapeutics Development

Pipeline Overview

Pipeline by Companies

Pipeline by Universities/Institutes

Drugs Under Development by Companies

Drugs under Development by Universities/Institutes

Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Companies Involved in Therapeutic Development

Drug Profiles

Dormant Projects

Discontinued Drugs

Product Development Milestones

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Drugs under Development, 2024

Number of Drugs under Development by Companies, 2024

Number of Drugs under Development by Universities/Institutes, 2024

Drugs under Development by Companies, 2024

Drugs under Development by Universities/Institutes, 2024

Number of Drugs by Stage and Target, 2024

Number of Drugs by Stage and Mechanism of Action, 2024

Number of Drugs by Stage and Route of Administration, 2024

Number of Drugs by Stage and Molecule Type, 2024

Dormant Projects, 2024

Discontinued Drugs, 2024

Figures

List of Figures

Number of Drugs under Development, 2024

Number of Drugs under Development by Companies, 2024

Number of Drugs under Development by Universities/Institutes, 2024

Number of Drugs by Top 10 Targets, 2024

Number of Drugs by Stage and Top 10 Targets, 2024

Number of Drugs by Top 10 Mechanism of Actions, 2024

Number of Drugs by Stage and Top 10 Mechanism of Actions, 2024

Number of Drugs by Top 10 Routes of Administration, 2024

Number of Drugs by Stage and Top 10 Routes of Administration, 2024

Number of Drugs by Top 10 Molecule Types, 2024

Number of Drugs by Stage and Top 10 Molecule Types, 2024

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