Net Present Value Model: Leuprorelin
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Overview
Evaluating the value of drugs is a complicated practice and requires a deep knowledge of the drug itself, the market currently and in the future, knowledge of cash inflows and outflows and the potential success rates for each stage of drug development. GlobalData has done all of this work for you, leveraging its gold standard Drugs Intelligence database to create high-value NPV models for purchase on a drug-by-drug basis.
Drug Operating Profit Model

Leuprorelin Drug Details
Leuprolide acetate (Tapros, Tapros 3M Depot, Lupron Depot, Lucrin Depot, Lucrin, Procrin, Prostap SR DCS, Lupron Depot-PED, Leuplin PRO and Enantone, Prostap PD DCS, Enantone-Gyn Monats-Depot, Enantone Monats-Depot, Lucrin PDS Depot, Sixantone, Trenantone, Enantone-Gyn Depot, Leuplin, Prostap 3 DCS, Lupron, Lucrin Depot PDS, Lucrin XL Depot, Ginecrin Depot, Procrin Trimestral, Procrin Semestral, Procrin Mensual, Procrin Depot, Enantone LP) is an gonadotropin-releasing hormone (GnRH) analog. It is formulated as solution and lyophilized powder for suspension for subcutaneous and intramuscular administration. It is indicated in the palliative treatment of advanced prostatic cancer, advanced breast cancer, endometriosis, including pain relief and reduction of endometriotic lesions. Concomitantly with iron therapy is indicated for the preoperative hematologic improvement of patients with anemia caused by uterine leiomyomata. Leuplin PRO indicated for the treatment of prostate cancer and premenopausal breast cancer. Lupron Depot-PED is indicated in the treatment of children with central precocious puberty (CPP). Lupron Depot 7.5 mg for 1-month administration, 22.5 mg for 3-month administration, 30 mg for 4 – month administration, and 45 mg for 6-month administr ation (leuprolide acetate) are indicated in the palliative treatment of advanced prostatic cancer. Prostap SR DCS is indicated for metastatic prostate cancer, locally advanced prostate cancer, as an alternative to surgical castration, as an adjuvant treatment to radiotherapy in patients with high-risk localised or locally advanced prostate cancer, as an adjuvant treatment to radical prostatectomy in patients with locally advanced prostate cancer at high risk of disease progression, as neo-adjuvant treatment prior to radiotherapy in patients with high-risk localised or locally advanced prostate cancer, management of endometriosis, including pain relief and reduction of endometriotic lesions, endometrial preparation prior to intrauterine surgical procedures including endometrial ablation or resection, preoperative management of uterine fibroids to reduce their size and associated bleeding.It is under development for the treatment of autosomal dominant polycystic liver disease, autosomal dominant polycystic kidney disease.It was under development for the treatment of spinal and bulbar muscular atrophy (SBMA). It is a sustained release formulation.
Report Coverage
GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, potential applicable patients, drug margins, company expenses, and pricing estimates. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company.
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Reasons to Buy
- Better understand the quantitative value of a specific drug
- Create or support internal NPV models to improve accuracy
- Understand the profit a drug is expected to make, taking into account revenue and cost forecasts leveraging public and proprietary data sets.
Frequently asked questions
- All drug sales and forecasts within NPV Model are calculated in our proprietary company based models . In these models, Analyst Consensus forecasts are built by using company-specific broker reports to create the sales forecasts for each Drug and Segment.
- Sales and forecasts are not indication-specific where drugs are approved , or in development, for multiple indications. Please refer to GlobalData’s Disease Analysis reports for indication-specific sales forecasts.
- Risk-adjusted NPVs use GlobalData’s LoA and PTSR for the indication in the highest development stage. Please refer to the Likelihood of Approval methodology for more details on this content.
GlobalData’s NPV Model is a premium model providing a fully-interactive forecasting and valuation tool, driven by Analyst Consensus estimates, enabling users to analyze and customize valuations for pharmaceutical assets including drugs or segments. The tool provides 17-year drug forecasts from companies with sales forecast data in the pharmaceutical industry, including established global firms and emerging biotechs, which allows access to critical information to facilitate strategic decision making around pharmaceutical assets
The NPV Model includes a forecasted Revenue Model, followed by a proprietary Patent Expiry Model, Operating Profit Model, Net Profit (apply Tax rate) and Discounted Cash Flow (apply Discount rates), to derive Net Present Value (NPV) for a chosen pharmaceutical asset
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