Mpox (Monkeypox) Marketed and Pipeline Drugs Assessment, Clinical Trials and Competitive Landscape

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Mpox Marketed and Pipeline Drugs Report Overview

Mpox (monkeypox) is an infectious disease caused by the monkeypox virus, an enveloped double-stranded DNA virus of the Orthopoxvirus genus in the Poxviridae family, which includes variola, cowpox, vaccinia, and other viruses. The two genetic clades of the virus are (Central Africa) clades I and (West Africa) Clade II. The current global outbreak (2022–23) is caused by Clade IIb, a subtype of the less severe West African clade. Poxviruses are brick-shaped, surrounded by a lipoprotein envelope with a linear double-stranded DNA genome. Viral replication takes place in the cytoplasm of the infected cell. Aside from their reliance on host ribosomes for messenger RNA (mRNA) translation, the poxvirus genome encodes all essential factors for replication, transcription, assembly, and egress.

Key Routes of Administration (Marketed) ·       Injection

·       Oral

Key Molecule Types (Marketed) ·       Biologic

·       Small Molecules

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The Mpox marketed and pipeline drugs market research report includes an assessment of the disease epidemiology, leading marketed products with sales forecast, and late-to-mid-stage pipeline products with Phase Transition Success Rate (PTSR) and Likelihood of Approval (LoA) for Mpox. The report also analyzes the clinical and commercial landscapes of Mpox, as well as an assessment of deals, future market catalysts, key market players, and the future competitive environment.

Key Mechanisms of Action ·       Antigen Inhibitor

·       Cell and Cell Organelle Disrupter

·       Protein and Peptide Inhibitor

·       Enzyme Inhibitor

Key Routes of Administration ·       Topical

·       Oral

·       Injection

·       Suppository

Key Molecule Types ·       Biologic

·       Small Molecules

Top Sponsors (Marketed and Pipeline Drugs) ·       National Institute of Allergy and Infectious Diseases

·       Japan Agency for Medical Research and Development

·       Assistance Publique – Hôpitaux de Paris

·       University of Oxford

·       University Hospital Geneva

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Mpox Marketed Drugs Segmentation by Routes of Administration

The key routes of administration for Mpox marketed drugs are injection and oral. In 2023, the most marketed drugs for Mpox are injectables.

Mpox Marketed Drugs Analysis by RoA, 2023 (%)

Mpox Marketed Drugs Analysis by RoA, 2023 (%)

For more RoA insights into the Mpox marketed drugs, download a free report sample

Mpox Marketed Drugs Segmentation by Molecule Type

In 2023, most of the marketed drugs for Mpox are biologic. The small molecule is another significant molecule type in the marketed drugs for Mpox.

Mpox Marketed Drugs Analysis by Molecule Types, 2023 (%)

Mpox Marketed Drugs Analysis by Molecule Types, 2023 (%)

For more molecule type insights into the Mpox marketed drugs market, download a free report sample

Mpox Pipeline Drugs Segmentation by Mechanisms of Action

The key mechanisms of action for Mpox pipeline drugs are antigen inhibitor, cell and cell organelle disrupter, protein and peptide inhibitor, and enzyme inhibitor. In 2023, all of the Mpox MoA has an equal number of drugs in the pipeline.

Mpox Pipeline Drugs Analysis by MoA, 2023 (%)

Mpox Pipeline Drugs Analysis by MoA, 2023 (%)

 For more MoA insights into the Mpox pipeline drugs market, download a free report sample

Mpox Pipeline Drugs Segmentation by Routes of Administration

The key routes of administration for Mpox pipeline drugs are injection, topical, oral, and suppository. In 2023, for all the Mpox pipeline drugs, injectable is the most common route of administration, followed by oral therapies.

Mpox Pipeline Drugs Analysis by RoA, 2023 (%)

Mpox Pipeline Drugs Analysis by RoA, 2023 (%)

For more RoA insights into the Mpox pipeline drugs market, download a free report sample

Mpox Pipeline Drugs Segmentation by Molecule Type

The key molecule types for the Mpox drugs market are biologics and small molecules. In 2023, the Mpox pipeline is mostly made up of biologics.

Mpox Pipeline Drugs Analysis by Molecule Types, 2023 (%)

Mpox Pipeline Drugs Analysis by Molecule Types, 2023 (%)

For more molecule type insights into the Mpox pipeline drugs market, download a free report sample

Top Sponsors in the Mpox Marketed and Pipeline Drugs Market

Some of the top sponsors in the Mpox marketed and pipeline drugs market are the National Institute of Allergy and Infectious Diseases, Japan Agency for Medical Research and Development, Assistance Publique – Hôpitaux de Paris, University of Oxford, and University Hospital Geneva among others. In 2023, in terms of ongoing trials, the National Institute of Allergy and Infectious Diseases leads among the non-commercial sponsors for Mpox.

Segments Covered in the Report

Mpox Marketed Drugs Routes of Administration Outlook (Number of Drugs, 2023)

  • Oral
  • Injection

Mpox Marketed Drugs Molecule Types Outlook (Number of Drugs, 2023)

  • Small Molecules
  • Biologic

Mpox Pipeline Drugs Mechanisms of Action Outlook (Number of Drugs, 2023)

  • Antigen Inhibitor
  • Cell and Cell Organelle Disrupter
  • Protein and Peptide Inhibitor
  • Enzyme Inhibitor

Mpox Pipeline Drugs Routes of Administration Outlook (Number of Drugs, 2023)

  • Topical
  • Oral
  • Injection
  • Suppository

Mpox Pipeline Drugs Molecule Types Outlook (Number of Drugs, 2023)

  • Small Molecule
  • Biologic

Scope

GlobalData’s Mpox Marketed and Pipeline Drugs Assessment, Clinical Trials, and Competitive Landscape combines data from the Pharma Intelligence Center with in-house analyst expertise to provide a competitive assessment of the disease marketplace.

Components of the report include:

  • Disease Landscape
  • Disease Overview
  • Epidemiology Overview
  • Treatment Overview
  • Marketed Products Assessment
  • Breakdown by Mechanism of Action, Molecule Type, Route of Administration
  • Product Profiles with Sales Forecast
  • Pricing and Reimbursement Assessment
  • Annual Therapy Cost
  • Time to Pricing and Time to Reimbursement
  • Pipeline Assessment
  • Breakdown by Development Stage, Mechanism of Action, Molecule Type, Route of Administration
  • Product Profiles with Sales Forecast
  • Late-to-mid-stage Pipeline Drugs
  • Phase Transition Success Rate and Likelihood of Approval
  • Clinical Trials Assessment
  • Breakdown of Trials by Phase, Status, Virtual Components, Sponsors, Geography, and Endpoint Status
  • Enrolment Analytics, Site Analytics, Feasibility Analysis
  • Deals Landscape
  • Mergers, Acquisitions, and Strategic Alliances by Region
  • Overview of Recent Deals
  • Commercial Assessment
  • Key Market Players
  • Future Market Catalysts

Reasons to Buy

  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the Mpox market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global Mpox market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and strategic partnerships.

Table of Contents

1 Preface

1.1 Contents

1.2 Report Scope

1.3 List of Tables and Figures

1.4 Abbreviations

2 Key Findings

3 Disease Landscape

3.1 Disease Overview

3.2 Epidemiology Overview

3.3 Treatment Overview

4 Marketed Drugs Assessment

4.1 Leading Marketed Drugs

4.2 Overview by Mechanism of Action

4.3 Overview by Route of Administration

4.4 Marketed Drugs Profiles and Sales Forecasts

5 Pricing and Reimbursement Assessment

5.1 Annual Therapy Cost

5.2 Time to Pricing and Reimbursement

6 Pipeline Drugs Assessment

6.1 Phase III Pipeline Drugs

6.2 Overview by Development Stage

6.3 Overview by Molecule Type

6.4 Overview by Mechanism of Action

6.5 Overview by Route of Administration

6.6 Drug Specific Phase Transition Success Rate (PTSR) and Likelihood of Approval (LoA)

6.7 Therapy Area and Indication-specific PTSR and LoA

7 Clinical Trials Assessment

7.1 Historical Overview

7.2 Overview by Phase

7.3 Overview by Status

7.4 Overview by Phase for Ongoing and Planned Trials

7.5 Trials with Virtual Components

7.6 Geographic Overview

7.7 Single-Country and Multinational Trials by Region

7.8 Top 20 Sponsors with Breakdown by Phase

7.9 Top 20 Sponsors with Breakdown by Status

7.10 Overview by Endpoint Status

7.11 Overview by Race and Ethnicity

7.12 Enrollment Data

7.13 Top 20 countries for Trial Sites

7.14 Top 20 Sites Globally

7.15 Feasibility Analysis – Geographic Overview

7.16 Feasibility Analysis – Benchmark Models

8 Deals Landscape

8.1 Mergers, Acquisitions, and Strategic Alliances by Region

8.2 Recent Mergers, Acquisitions, and Strategic Alliances

9 Commercial Assessment

9.1 Key Market Players

10 Future Market Catalysts

11 Appendix

11.1 Methodology

11.2 Methodology – Sales Forecast

11.3 Methodology – Pricing and Reimbursement

11.4 Methodology – PTSR and LoA Analysis

11.5 About the Authors

11.6 Contact Us

11.7 Disclaimer

Frequently asked questions

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