Mpox (Monkeypox) Marketed and Pipeline Drugs Assessment, Clinical Trials and Competitive Landscape
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Mpox Marketed and Pipeline Drugs Report Overview
Mpox (monkeypox) is an infectious disease caused by the monkeypox virus, an enveloped double-stranded DNA virus of the Orthopoxvirus genus in the Poxviridae family, which includes variola, cowpox, vaccinia, and other viruses. The two genetic clades of the virus are (Central Africa) clades I and (West Africa) Clade II. The current global outbreak (2022–23) is caused by Clade IIb, a subtype of the less severe West African clade. Poxviruses are brick-shaped, surrounded by a lipoprotein envelope with a linear double-stranded DNA genome. Viral replication takes place in the cytoplasm of the infected cell. Aside from their reliance on host ribosomes for messenger RNA (mRNA) translation, the poxvirus genome encodes all essential factors for replication, transcription, assembly, and egress.
The Mpox marketed and pipeline drugs market research report includes an assessment of the disease epidemiology, leading marketed products with sales forecast, and late-to-mid-stage pipeline products with Phase Transition Success Rate (PTSR) and Likelihood of Approval (LoA) for Mpox. The report also analyzes the clinical and commercial landscapes of Mpox, as well as an assessment of deals, future market catalysts, key market players, and the future competitive environment.
Leading Marketed Drugs in Mpox
The leading marketed drugs in Mpox are Jynneos (Imvanex/Imvamune), Tecovirimat (Tpoxx), and monkeypox [strain LC16m8] vaccinex. Tecovirimat (Tpoxx) is the only approved medication for the treatment of severe complications of mpox that is available in both an oral and intravenous formulation. Currently, several other antiviral medications are used off-label to treat patients with mpox. These off-label antivirals include: brincidofovir (Tembexa), which is approved for smallpox, and cidofovir (Vistide), an intravenously administered antiviral approved to treat cytomegalovirus retinitis in patients with HIV.
Top Sponsors in the Mpox Marketed and Pipeline Drugs Market
A few of the top sponsors in the Mpox marketed and pipeline drugs market are the National Institute of Allergy and Infectious Diseases, Japan Agency for Medical Research and Development, Assistance Publique – Hôpitaux de Paris, University of Oxford, and University Hospital Geneva among others.
Mpox Marketed and Pipeline Drugs Market Sponsor Analysis
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Mpox Marketed Drugs Segmentation by Molecule Type
Most of the marketed drugs for Mpox are biologic. The small molecule is another significant molecule type in the marketed drugs for Mpox.
Mpox Marketed Drugs Analysis by Molecule Types
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Mpox Pipeline Drugs Segmentation by Mechanisms of Action
The key mechanisms of action for Mpox pipeline drugs are antigen inhibitor, cell and cell organelle disrupter, protein and peptide inhibitor, and enzyme inhibitor. All the Mpox MoA has an equal number of drugs in the pipeline.
Mpox Pipeline Drugs Segmentation by Routes of Administration
The key routes of administration for Mpox pipeline drugs are injection, topical, oral, and suppository. Injectable is the most common route of administration, followed by oral therapies.
Mpox Pipeline Drugs Analysis by RoA
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Mpox Pipeline Drugs Segmentation by Molecule Type
The key molecule types for the Mpox drugs market are biologics and small molecule. The Mpox pipeline is mostly made up of biologics.
Mpox Pipeline Drugs Analysis by Molecule Types
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Mpox Marketed and Pipeline Drugs – Deals Landscape
- On 1st Feb 2023, On Blue Water Vaccines enters into co-development agreement with AbVacc
- On 12th Oct 2022, Emergex Vaccines acquires Zosano Pharma
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| Key Routes of Administration (Marketed) | · Injection
· Oral |
| Key Molecule Types (Marketed) | · Biologic
· Small Molecule |
| Key Mechanisms of Action (Pipeline) | · Antigen Inhibitor
· Cell and Cell Organelle Disrupter · Protein and Peptide Inhibitor · Enzyme Inhibitor |
| Key Routes of Administration (Pipeline) | · Topical
· Oral · Injection · Suppository |
| Key Molecule Types (Pipeline) | · Biologic
· Small Molecule |
| Top Sponsors (Marketed and Pipeline Drugs) | · National Institute of Allergy and Infectious Diseases
· Japan Agency for Medical Research and Development · Assistance Publique – Hôpitaux de Paris · University of Oxford · University Hospital Geneva |
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Segments Covered in the Report
Mpox Marketed Drugs Routes of Administration Outlook (Number of Drugs)
- Oral
- Injection
Mpox Marketed Drugs Molecule Types Outlook (Number of Drugs)
- Small Molecules
- Biologic
Mpox Pipeline Drugs Mechanisms of Action Outlook (Number of Drugs)
- Antigen Inhibitor
- Cell and Cell Organelle Disrupter
- Protein and Peptide Inhibitor
- Enzyme Inhibitor
Mpox Pipeline Drugs Routes of Administration Outlook (Number of Drugs)
- Topical
- Oral
- Injection
- Suppository
Mpox Pipeline Drugs Molecule Types Outlook (Number of Drugs)
- Small Molecule
- Biologic
Scope
GlobalData’s Mpox Marketed and Pipeline Drugs Assessment, Clinical Trials, and Competitive Landscape combines data from the Pharma Intelligence Center with in-house analyst expertise to provide a competitive assessment of the disease marketplace.
Components of the report include:
- Disease Landscape
- Disease Overview
- Epidemiology Overview
- Treatment Overview
- Marketed Products Assessment
- Breakdown by Mechanism of Action, Molecule Type, Route of Administration
- Product Profiles with Sales Forecast
- Pricing and Reimbursement Assessment
- Annual Therapy Cost
- Time to Pricing and Time to Reimbursement
- Pipeline Assessment
- Breakdown by Development Stage, Mechanism of Action, Molecule Type, Route of Administration
- Product Profiles with Sales Forecast
- Late-to-mid-stage Pipeline Drugs
- Phase Transition Success Rate and Likelihood of Approval
- Clinical Trials Assessment
- Breakdown of Trials by Phase, Status, Virtual Components, Sponsors, Geography, and Endpoint Status
- Enrolment Analytics, Site Analytics, Feasibility Analysis
- Deals Landscape
- Mergers, Acquisitions, and Strategic Alliances by Region
- Overview of Recent Deals
- Commercial Assessment
- Key Market Players
- Future Market Catalysts
Reasons to Buy
- Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
- Develop business strategies by understanding the trends shaping and driving the Mpox market.
- Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global Mpox market in the future.
- Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
- Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
- Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and strategic partnerships.
Table of Contents
Frequently asked questions
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Which is the leading RoA for Mpox-marketed drugs?
Injectables is the leading RoA for Mpox-marketed drugs.
-
Which is the leading molecule type for Mpox-marketed drugs?
Biologic is the leading molecule type for Mpox-marketed drugs.
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Who are the top sponsors for Mpox marketed and pipeline drugs market?
A few of the top sponsors in the Mpox marketed and pipeline drugs market are the National Institute of Allergy and Infectious Diseases, Japan Agency for Medical Research and Development, Assistance Publique – Hôpitaux de Paris, University of Oxford, and University Hospital Geneva among others.
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Sample Report
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