Nanotechnology in Medicine – Thematic Research

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Nanotechnology in Medicine Report Overview

A persistent problem in medicine is the lack of ability to specifically target diseased cells and tissues. Drugs are often administered as free compounds. This non-specific mode of delivery relies on the drug molecules to serendipitously reach target cells. Nanomedicine refers to the area of science that combines nanotechnology with drugs or diagnostic molecules to improve the ability to target specific cells or tissues. These materials are produced on a nanoscale level and are safe to introduce into the body. Applications for nanotechnology in medicine include imaging, diagnosis, or the delivery of drugs that will help medical professionals treat various diseases.

The nanotechnology in medicine research report will focus on nanotechnology and nanomedicines that are currently approved by the FDA. Specifically, the nanotechnology that will be covered includes liposomes, microbubbles, and nanoparticles. All these technologies are approved either on their own or in combination with specific drugs.

Key trends Technology Trends, Macroeconomic Trends, and Regulatory Trends
Key value chains Imaging, Diagnostics, and Therapy
Leading public companies Amgen, Bausch Health Companies, Biogen, Celgene, Eisai, F. Hoffmann-La Roche, Gilead Sciences, Ipsen, Jazz Pharmaceuticals, Lantheus Holdings, Merck, and Novo Nordisk
Leading private companies AlfaSigma, Dompe Farmaceutici, GE Healthcare, Horizon Pharmaceuticals, and Janssen Pharmaceuticals

Trends That Will Impact the Nanotechnology in Medicine Theme

The key trends that will impact the nanotechnology in medicine theme in the coming months can be divided into three categories: technology trends, macroeconomic trends, and regulatory trends.

Technology trends

The main technology trends that will impact the nanotechnology in medicine theme are target specification, controlled drug release, and understanding different patient populations.

Macroeconomic trends

The main macroeconomic trends that will impact the nanotechnology in medicine theme are clinical trials, lack of nanomaterial experts, mergers & acquisitions, and nanomedicine production.

Regulatory trends

The main regulatory trends that will impact the nanotechnology in medicine theme are FDA regulation of nanotechnology, government & regulatory agencies, and patents & IP.

Nanotechnology in Medicine Value Chains Analysis

The key nanotechnology in medicine value chains can be divided into three segments: imaging, diagnostics, and therapy.

Imaging

Microbubbles are approved by the FDA as imaging contrast agents. They can be injected intravenously into patients and enhance imaging techniques, such as ultrasound by vibrating upon stimulation by energy. Currently, the market is dominated by three companies: Lantheus Holdings, Dompe Farmaceutici, and GE Healthcare, which manufacture the FDA-approved products Definity, Lumason, and Optison, respectively.

Diagnostics

While not yet clinically approved, liposomes have been studied for the diagnosis of various diseases. For example, PEGylated liposomes have been demonstrated to be useful for the diagnosis of obstructed coronary arteries that can lead to ischemic myocardium. In addition, liposomes encapsulating fluorescent dye have been used for the diagnosis of cerebral malaria and inflammation. Finally, liposomes have been proven to be useful for the diagnosis of various tumors upon update by various types of cancer cells, including breast cancer cells. Once the liposomes interact with the tumors, signals are generated by pH changes and can be detected by clinicians.

Therapy

Nanotechnology in medicine is predominantly used for therapeutic purposes. Currently, there are over 25 different nanomedicines approved by the FDA for indications such as oncology, pain relief, macular degeneration, Crohn’s disease, multiple sclerosis, and hemophilia. These nanomedicines use liposomes and other nanoparticle-drug conjugates to deliver, increase the efficiency of uptake by tissues, or prolong the half-life of various drugs.

Leading Public Companies Associated with the Nanotechnology in Medicine Theme

Some of the leading public companies associated with the nanotechnology in medicine theme are Amgen, Bausch Health Companies, Biogen, Celgene, Eisai, F. Hoffmann-La Roche, Gilead Sciences, Ipsen, Jazz Pharmaceuticals, Lantheus Holdings, Merck, and Novo Nordisk.

Leading Private Companies Associated with the Nanotechnology in Medicine Theme

The leading private companies associated with the nanotechnology in medicine theme are AlfaSigma, Dompe Farmaceutici, GE Healthcare, Horizon Pharmaceuticals, and Janssen Pharmaceuticals.

For more insights on the nanotechnology in medicine theme, download a free report sample

Key Highlights

This report focuses on nanotechnology and nanomedicines that are currently approved by the FDA.

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Janssen
Bausch & Lomb
Pacira Pharma
Ipsen Biopharm
Jazz Pharma
GE Healthcare
Lantheus
F. Hoffman-La Roche
Merck
Sanofi

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