Pulmonary Arterial Hypertension – Drugs In Development, 2024

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Published: June 05, 2024 Report Code: GDGMDHC23049IDB-L5

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Pulmonary arterial hypertension (PAH) is a type of high blood pressure that occurs in the right side of the heart and in the arteries that supply blood to the lungs. Symptoms include chest pain, fatigue, passing out suddenly, and swelling of the legs (edema). Risk factors include family history, age, obesity, obstructive sleep apnea, and other diseases, including congenital heart disease, lung disease, liver disease, and connective tissue disorders like scleroderma and lupus. Treatment includes sildenafil, prostanoids, and calcium channel blockers.

The Pulmonary Arterial Hypertension drugs in development market research report provide comprehensive information on the therapeutics under development for Pulmonary Arterial Hypertension, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action and product description of the therapeutics, and the latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Pulmonary Arterial Hypertension and features dormant and discontinued products.

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* This is an “on-demand” report and will be delivered within 2 business days (excluding weekends and holidays) of the purchase.

* Certain sections in the report may be removed or altered based on the availability and relevance of data.

Quick View – Pulmonary Arterial Hypertension
Key Targets
· Prostacyclin Receptor; cGMP Specific 3',5' Cyclic Phosphodiesterase; Platelet Derived Growth Factor Receptor; Thromboxane A2 Receptor; Endothelin 1 Receptor; Mast/Stem Cell Growth Factor Receptor Kit; Soluble Guanylate Cyclase; Endothelial PAS Domain Containing Protein 1; Inhibin Beta B Chain; and Endothelin Receptor Type B
Key Mechanisms of Action
· Prostacyclin Receptor Agonist; cGMP Specific 3',5' Cyclic Phosphodiesterase Inhibitor; Endothelin 1 Receptor Antagonist; Thromboxane A2 Receptor Antagonist; Soluble Guanylate Cyclase Activator; Platelet Derived Growth Factor Receptor Inhibitor; Mast/Stem Cell Growth Factor Receptor Kit Inhibitor; Endothelial PAS Domain Containing Protein 1 Inhibitor; E3 Ubiquitin Protein Ligase SMURF1 Inhibitor; and Endothelin Receptor Type B Antagonist
Key Routes of Administration
· Oral; Inhalational; Intravenous; Subcutaneous; Topical; Parenteral; Intramuscular; Intracoronary; Intravesical; and Nasal
Key Molecule Types
· Small Molecule; Monoclonal Antibody; Fusion Protein; Oligonucleotide; Gene-Modified Cell Therapy; Peptide; Protein; Recombinant Enzyme; Recombinant Peptide; and Polysaccharide
Major Companies
· United Therapeutics Corp; ATXA Therapeutics Ltd; Chiesi Farmaceutici SpA; Johnson & Johnson; Merck & Co Inc; Novartis AG; Boehringer Ingelheim International GmbH; Bayer AG; AstraZeneca Plc; and Antlia Bioscience Inc

Scope

  • Therapeutics in Development: Covering 129 molecules, with 120 developed by companies and the rest by universities/institutes.

  • Analysis Parameters: Offering insights by stage of development, drug target, MoA, RoA, and molecule type for a comprehensive overview.

  • Pharmacological Insights: Understand the descriptive pharmacological action of therapeutics.

  • Development History: Access the complete research and development history.

  • Latest News and Press Releases: Stay updated with the latest developments through comprehensive news coverage.

Reasons to Buy

  • Holistic insights: Understand the broad spectrum of Pulmonary Arterial Hypertension therapeutics, aiding strategic decision-making with insights into stages, targets, MoA, RoA and molecule types.

  • Pipeline Exploration: Explore the detailed Pulmonary Arterial Hypertension pipeline, offering nuanced analysis of drug targets, mechanisms of action and routes of administration for varied decision-making.

  • Comprehensive R&D: Access thorough R&D histories, providing a comprehensive understanding of Pulmonary Arterial Hypertension treatments for adaptable decision-making.

  • Save valuable hours: Identify key players steering innovation in therapeutics, enabling strategic partnerships.

Key Players

Aadi Bioscience Inc
Abivax SA
Actelion Pharmaceuticals Ltd
Advantx Pharmaceuticals Inc
Advent Therapeutics Inc
Aeon Respire Inc
Aerami Therapeutics Inc
Aerovate Therapeutics Inc
Algorithm Sciences Inc
Alsymo
Alterras Therapeutics GmbH
Alveolus Bio Inc
Antlia Bioscience Inc
Apaxen
APEIRON Biologics AG
APT Therapeutics Inc
Aqualung Therapeutics Corp
Artin Bioscience Inc
AstraZeneca Plc
ATXA Therapeutics Ltd
Audax Therapeutics Ltd
Bayer AG
Biogen Inc
Biozeus Pharmaceutical SA
Boehringer Ingelheim International GmbH
Camurus AB
Capricor Therapeutics Inc
Celon Pharma SA
Cereno Scientific AB
Chengdu Dikang Pharmaceuticals Co Ltd
Chiesi Farmaceutici SpA
Claritas Pharmaceuticals Inc
Corsair Pharma Inc
Eli Lilly and Co
EspeRare Foundation
Everest Medicines Ltd
Excubio Pharmaceuticals Inc
Foresee Pharmaceuticals Co Ltd
Galectin Therapeutics Inc
GenThera Inc
GEXVal Inc
Gmax Biopharm LLC
GNI Group Ltd
Gossamer Bio Inc
Guangdong East Sunshine Pharmaceutical Co Ltd
Guangzhou Magpie Pharmaceutical Co Ltd
Hanmi Pharmaceuticals Co Ltd
Hunterian Medicine LLC
Imunon Inc
Insmed Inc
Interprotein Corp
Japan Tobacco Inc
Johnson & Johnson
KARE Biosciences Inc
Keros Therapeutics Inc
Lempo Therapeutics Ltd
Liquidia Corp
LTT Bio-Pharma Co Ltd
Mallinckrodt Plc
Merck & Co Inc
Mochida Pharmaceutical Co Ltd
Morphic Therapeutic Inc
Nadian Bio Ltd
Nippon Shinyaku Co Ltd
Nissan Chemical Corp
Northern Therapeutics Inc
Northwestern University
Novartis AG
OrphAI Therapeutics Inc
Osaka University
Pfizer Inc
Pharmosa Biopharm Inc
PulmoSIM Therapeutics
Q BioMed Inc
Radikal Therapeutics Inc
Recursion Pharmaceuticals Inc
Respira Therapeutics Inc
Resverlogix Corp
Reviva Pharmaceuticals Inc
Ribomic Inc
San Rocco Therapeutics LLC
Sanofi
Schrodinger Inc
Shanghai Aoquan Biomedical Technology Co Ltd
Shanghai Institute of Materia Medica Chinese Academy of Sciences
Shiftbio Co Ltd
Structure Therapeutics Inc
Sulfateq BV
Systimmune Inc
Talem Therapeutics Inc
Tenax Therapeutics Inc
tiakis BIOTECH AG
Topadur Pharma AG
Triastek Inc
Tritech Biopharmaceuticals Co Ltd
United Therapeutics Corp
University of California San Diego
University of Cambridge
University of Pennsylvania
University of Strathclyde
Vascular BioSciences
Vasculonics LLC
VasoRx Inc
VasThera Co Ltd
Vicore Pharma AB
Vivus LLC
Voronoi Group
Wuxi Biocity Biopharma Co Ltd
Yale University
Zymedi

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Overview

Therapeutics Development

Pipeline Overview

Pipeline by Companies

Pipeline by Universities/Institutes

Drugs Under Development by Companies

Drugs under Development by Universities/Institutes

Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Companies Involved in Therapeutic Development

Drug Profiles

Dormant Projects

Discontinued Drugs

Product Development Milestones

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Drugs under Development, 2024

Number of Drugs under Development by Companies, 2024

Number of Drugs under Development by Universities/Institutes, 2024

Drugs under Development by Companies, 2024

Drugs under Development by Universities/Institutes, 2024

Number of Drugs by Stage and Target, 2024

Number of Drugs by Stage and Mechanism of Action, 2024

Number of Drugs by Stage and Route of Administration, 2024

Number of Drugs by Stage and Molecule Type, 2024

Dormant Projects, 2024

Discontinued Drugs, 2024

Figures

List of Figures

Number of Drugs under Development, 2024

Number of Drugs under Development by Companies, 2024

Number of Drugs under Development by Universities/Institutes, 2024

Number of Drugs by Top 10 Targets, 2024

Number of Drugs by Stage and Top 10 Targets, 2024

Number of Drugs by Top 10 Mechanism of Actions, 2024

Number of Drugs by Stage and Top 10 Mechanism of Actions, 2024

Number of Drugs by Top 10 Routes of Administration, 2024

Number of Drugs by Stage and Top 10 Routes of Administration, 2024

Number of Drugs by Top 10 Molecule Types, 2024

Number of Drugs by Stage and Top 10 Molecule Types, 2024

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