Transthyretin (ATTR or Prealbumin or TBPA or TTR) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

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Transthyretin is a transport protein that transports thyroid hormones and retinol (vitamin A). The Transthyretin pipeline drugs market research report outlays comprehensive information on the Transthyretin (ATTR or Prealbumin or TBPA or TTR) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also reviews key players involved in Transthyretin (ATTR or Prealbumin or TBPA or TTR) targeted therapeutics development with respective active and dormant or discontinued projects.

Transthyretin Pipeline Drugs Market Segmentation by Therapy Areas

The key therapy areas in the Transthyretin pipeline drugs market are metabolic disorders, ophthalmology, central nervous system, gastrointestinal, immunology, and infectious disease.

Transthyretin Pipeline Drugs Market Analysis, by Therapy Areas, 2022 (%)

Transthyretin Pipeline Drugs Market Analysis, by Therapy Areas

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Transthyretin Pipeline Drugs Market Segmentation by Mechanism of Actions

The key mechanism of actions in the Transthyretin pipeline drugs market are Transthyretin Inhibitor and Transthyretin Activator.

Transthyretin Pipeline Drugs Market Analysis, by Mechanism of Actions, 2022 (%)

Transthyretin Pipeline Drugs Market Analysis, by Mechanism of Actions

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Transthyretin Pipeline Drugs Market Segmentation by Routes of Administration

The key routes of administration in the Transthyretin pipeline drugs market are intravenous, subcutaneous, oral, and parenteral.

Transthyretin Pipeline Drugs Market Analysis, by Routes of Administration, 2022 (%)

Transthyretin Pipeline Drugs Market Analysis, by Routes of Administration

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Transthyretin Pipeline Drugs Market Segmentation by Molecule Types

The key molecule types in the Transthyretin pipeline drugs market are small molecule, antisense RNAi oligonucleotide, monoclonal antibody, antisense oligonucleotide, gene therapy, synthetic peptide, antibody, and fusion protein.

Transthyretin Pipeline Drugs Market Analysis, by Molecule Types, 2022 (%)

Transthyretin Pipeline Drugs Market Analysis, by Molecule Types

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Competitive Landscape

Some of the leading companies in the Transthyretin pipeline drugs market are ADRx Inc, Akcea Therapeutics Inc, Alexion Pharmaceuticals Inc, Alnylam Pharmaceuticals Inc, Autotac Bio Inc, BridgeBio Pharma Inc, BSIM Therapeutics SA, Corino Therapeutics Inc, Covalent Bioscience Inc, and Galmed Pharmaceuticals Ltd.

Transthyretin Pipeline Drugs Market Analysis, by Companies, 2022 (%)

Transthyretin Pipeline Drugs Market Analysis, by Companies

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Transthyretin Pipeline Drugs Market Report Overview

Key Therapy Areas Metabolic Disorders, Ophthalmology, Central Nervous System, Gastrointestinal, Immunology, and Infectious Disease
Key Mechanism of Actions Transthyretin Inhibitor and Transthyretin Activator
Key Routes of Administration Intravenous, Subcutaneous, Oral, and Parenteral
Key Molecule Types Small Molecule, Antisense RNAi Oligonucleotide, Monoclonal Antibody, Antisense Oligonucleotide, Gene Therapy, Synthetic Peptide, Antibody, and Fusion Protein
Leading Companies ADRx Inc, Akcea Therapeutics Inc, Alexion Pharmaceuticals Inc, Alnylam Pharmaceuticals Inc, Autotac Bio Inc, BridgeBio Pharma Inc, BSIM Therapeutics SA, Corino Therapeutics Inc, Covalent Bioscience Inc, and Galmed Pharmaceuticals Ltd

Segments Covered in the Report

Transthyretin Pipeline Drugs Market Therapy Areas Outlook

  • Metabolic Disorders
  • Ophthalmology
  • Central Nervous System
  • Gastrointestinal
  • Immunology
  • Infectious Disease

Transthyretin Pipeline Drugs Market Mechanism of Actions Outlook

  • Transthyretin Inhibitor
  • Transthyretin Activator

Transthyretin Pipeline Drugs Market Routes of Administration Outlook

  • Intravenous
  • Subcutaneous
  • Oral
  • Parenteral

Transthyretin Pipeline Drugs Market Molecule Types Outlook

  • Small Molecule
  • Antisense RNAi Oligonucleotide
  • Monoclonal Antibody
  • Antisense Oligonucleotide
  • Gene Therapy
  • Synthetic Peptide
  • Antibody
  • Fusion Protein

Scope

This report provides:

  • A snapshot of the global therapeutic landscape for Transthyretin (ATTR or Prealbumin or TBPA or TTR).
  • Reviews of Transthyretin (ATTR or Prealbumin or TBPA or TTR) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • Pipeline products based on various stages of development ranging from pre-registration to discovery and undisclosed stages.
  • Descriptive drug profiles for the pipeline products which includes product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities.
  • Reviews of key players involved in Transthyretin (ATTR or Prealbumin or TBPA or TTR) targeted therapeutics and enlists all their major and minor projects.
  • Assessment of Transthyretin (ATTR or Prealbumin or TBPA or TTR) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA), and molecule type.
  • Summaries of all the dormant and discontinued pipeline projects.
  • Reviews of the latest news and deals related to Transthyretin (ATTR or Prealbumin or TBPA or TTR) targeted therapeutics.

Reasons to Buy

  • Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies.
  • Identify emerging players with potentially strong product portfolio and create effective counterstrategies to gain competitive advantage.
  • Identify and understand the targeted therapy areas and indications for Transthyretin (ATTR or Prealbumin or TBPA or TTR). Identify the use of drugs for target identification and drug repurposing.
  • Identify potential new clients or partners in the target demographic.
  • Develop strategic initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions effectively by identifying key players and their most promising pipeline therapeutics.
  • Devise corrective measures for pipeline projects by understanding Transthyretin (ATTR or Prealbumin or TBPA or TTR) development landscape.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.

ADRx Inc
Akcea Therapeutics Inc
Alexion Pharmaceuticals Inc
Alnylam Pharmaceuticals Inc
Autotac Bio Inc
BridgeBio Pharma Inc
BSIM Therapeutics SA
Corino Therapeutics Inc
Covalent Bioscience Inc
Galmed Pharmaceuticals Ltd
Novo Nordisk AS
Proclara Biosciences Inc
Regeneron Pharmaceuticals Inc

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Transthyretin (ATTR or Prealbumin or TBPA or TTR) – Overview

Transthyretin (ATTR or Prealbumin or TBPA or TTR) – Therapeutics Development

Products under Development by Stage of Development

Products under Development by Therapy Area

Products under Development by Indication

Products under Development by Companies

Products under Development by Universities/Institutes

Transthyretin (ATTR or Prealbumin or TBPA or TTR) – Therapeutics Assessment

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Transthyretin (ATTR or Prealbumin or TBPA or TTR) – Companies Involved in Therapeutics Development

ADRx Inc

Akcea Therapeutics Inc

Alexion Pharmaceuticals Inc

Alnylam Pharmaceuticals Inc

Autotac Bio Inc

BridgeBio Pharma Inc

BSIM Therapeutics SA

Corino Therapeutics Inc

Covalent Bioscience Inc

Galmed Pharmaceuticals Ltd

Novo Nordisk AS

Proclara Biosciences Inc

Regeneron Pharmaceuticals Inc

Transthyretin (ATTR or Prealbumin or TBPA or TTR) – Drug Profiles

acoramidis hydrochloride – Drug Profile

Product Description

Mechanism Of Action

History of Events

ALNTTRSC-04 – Drug Profile

Product Description

Mechanism Of Action

History of Events

Amilo-5MER – Drug Profile

Product Description

Mechanism Of Action

History of Events

Antibody to Inhibit TTR for Familial Transthyretin Amyloidosis – Drug Profile

Product Description

Mechanism Of Action

History of Events

ATC-202 – Drug Profile

Product Description

Mechanism Of Action

doxycycline hyclate – Drug Profile

Product Description

Mechanism Of Action

History of Events

eplontersen sodium – Drug Profile

Product Description

Mechanism Of Action

History of Events

inotersen sodium – Drug Profile

Product Description

Mechanism Of Action

History of Events

Monoclonal Antibody for Familial Amyloid Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

History of Events

NI-006 – Drug Profile

Product Description

Mechanism Of Action

History of Events

NPT-189 – Drug Profile

Product Description

Mechanism Of Action

History of Events

NTLA-2001 – Drug Profile

Product Description

Mechanism Of Action

History of Events

patisiran – Drug Profile

Product Description

Mechanism Of Action

History of Events

PRX-004 – Drug Profile

Product Description

Mechanism Of Action

History of Events

Small Molecules to Inhibit Transthyretin for Ophthalmology – Drug Profile

Product Description

Mechanism Of Action

tafamidis meglumine – Drug Profile

Product Description

Mechanism Of Action

History of Events

tolcapone – Drug Profile

Product Description

Mechanism Of Action

History of Events

vutrisiran – Drug Profile

Product Description

Mechanism Of Action

History of Events

Transthyretin (ATTR or Prealbumin or TBPA or TTR) – Dormant Products

Transthyretin (ATTR or Prealbumin or TBPA or TTR) – Discontinued Products

Transthyretin (ATTR or Prealbumin or TBPA or TTR) – Product Development Milestones

Featured News & Press Releases

Aug 18, 2022: Alnylam to present data from the APOLLO-B phase 3 study of patisiran in patients with ATTR amyloidosis with cardiomyopathy at the 18th International Symposium on amyloidosis

Aug 03, 2022: Alnylam reports positive topline results from APOLLO-B phase 3 study of patisiran in patients with ATTR amyloidosis with cardiomyopathy

Jul 22, 2022: Alnylam receives positive CHMP opinion for vutrisiran for the treatment of hereditary transthyretin-mediated (hATTR) amyloidosis in adult patients with stage 1 or stage 2 polyneuropathy

Jul 20, 2022: Orsini Specialty Pharmacy selected as limited distribution partner for AMVUTTRA (vutrisiran)

Jun 24, 2022: Intellia and Regeneron present updated interim data from phase 1 Study of CRISPR-based NTLA-2001 for the treatment of transthyretin (ATTR) amyloidosis demonstrating that deep serum TTR reductions remained durable after a single dose

Jun 22, 2022: AstraZeneca-Ionis’ eplontersen meets endpoints in Phase III ATTRv-PN trial

Jun 13, 2022: Alnylam announces FDA approval of AMVUTTRA (vutrisiran), an RNAi therapeutic for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults

Jun 08, 2022: Intellia Therapeutics to present updated interim clinical data from ongoing phase 1 study of NTLA-2001 for the treatment of transthyretin (ATTR) amyloidosis at the International Liver Congress 2022

May 23, 2022: Alnylam presents new 18-month results from exploratory cardiac endpoints in HELIOS-A phase 3 study of investigational vutrisiran

Apr 04, 2022: Alnylam announces 3-Month extension of review period for New Drug Application for Vutrisiran

Apr 03, 2022: BridgeBio Pharma presents updated rsults from phase 2 open-label extension study of Acoramidis in transthyretin amyloid cardiomyopathy (ATTR-CM)

Mar 28, 2022: BridgeBio Pharma to present updated results from phase 2 open-label extension study of Acoramidis in Transthyretin Amyloid Cardiomyopathy (ATTR-CM) at the American College of Cardiology (ACC) Annual Scientific Session & Expo

Mar 01, 2022: Intellia, Regeneron report positive Phase I transthyretin amyloidosis data

Feb 17, 2022: Intellia Therapeutics announces two upcoming investor events in February 2022

Jan 24, 2022: Eplontersen granted Orphan Drug Designation in the US for transthyretin amyloidosis

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Products under Development by Stage of Development, 2022

Number of Products under Development by Therapy Areas, 2022

Number of Products under Development by Indication, 2022

Number of Products under Development by Companies, 2022

Products under Development by Companies, 2022

Products under Development by Companies, 2022 (Contd..1)

Products under Development by Companies, 2022 (Contd..2)

Number of Products under Investigation by Universities/Institutes, 2022

Products under Investigation by Universities/Institutes, 2022

Number of Products by Stage and Mechanism of Actions, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Pipeline by ADRx Inc, 2022

Pipeline by Akcea Therapeutics Inc, 2022

Pipeline by Alexion Pharmaceuticals Inc, 2022

Pipeline by Alnylam Pharmaceuticals Inc, 2022

Pipeline by Autotac Bio Inc, 2022

Pipeline by BridgeBio Pharma Inc, 2022

Pipeline by BSIM Therapeutics SA, 2022

Pipeline by Corino Therapeutics Inc, 2022

Pipeline by Covalent Bioscience Inc, 2022

Pipeline by Galmed Pharmaceuticals Ltd, 2022

Pipeline by Novo Nordisk AS, 2022

Pipeline by Proclara Biosciences Inc, 2022

Pipeline by Regeneron Pharmaceuticals Inc, 2022

Dormant Projects, 2022

Discontinued Products, 2022

Figures

List of Figures

Number of Products under Development by Stage of Development, 2022

Number of Products under Development by Therapy Areas, 2022

Number of Products under Development by Top 10 Indications, 2022

Number of Products by Mechanism of Actions, 2022

Number of Products by Stage and Mechanism of Actions, 2022

Number of Products by Routes of Administration, 2022

Number of Products by Stage and Routes of Administration, 2022

Number of Products by Molecule Types, 2022

Number of Products by Stage and Molecule Types, 2022

Frequently asked questions

Transthyretin (ATTR or Prealbumin or TBPA or TTR) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update standard reports
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