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The pharmaceutical market for age-related macular degeneration (AMD) was worth an estimated $8.6bn across the nine major markets (9MM*) in 2018. This is expected to grow to $18.7bn in 2028 at a modest compound annual growth rate (CAGR) of 8.1%, according to GlobalData, a leading data and analytics company. GlobalData’s latest report, ‘Age-Related Macular Degeneration: Global Drug Forecast and Market Analysis to 2028’, explains that growth in the market will be driven by the entry of longer-acting anti-angiogenic therapies and the launch […]
Healthcare sector witnesses decline in deal activity during the week ended April 12
The number of deals announced in the global healthcare sector (including pharmaceuticals and medical equipment) declined by 28% during the week ended April 12, 2020 compared to the previous week, according to GlobalData’s deals database. Aurojyoti Bose, Analyst at GlobalData, comments: “The decline was subsequent to two consecutive weeks of growth in deal activity. Deal activity in the healthcare sector has remained inconsistent due to uncertainty and volatile market conditions since the coronavirus outbreak.” Deal activity declined in the key markets such as the US and China during the week ended April 12. The announcement of venture financing, partnership, licensing agreement and merger and […]
Protease inhibitors could benefit from being trialled with milder cases of COVID-19
AbbVie was one of the first companies to donate its combination of HIV protease inhibitors Aluvia (lopinavir/ritonavir), also known as Kaletra, to help China treat patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, more recent investigations show that treatment with lopinavir-ritonavir does not actually provide a substantial benefit beyond standard care*, says GlobalData, a leading data and analytics company. Angad Lotay, MPharm, Infectious Diseases Analyst at GlobalData, […]
Government initiatives minimize Indian pharma industry manufacturing and supply chain disruptions amid Covid-19 crisis, says GlobalData
India’s coronavirus (Covid-19) lockdown has impacted the manufacturing and supply chain operations of pharmaceuticals despite pharmaceutical manufacturing being considered an essential service and excluded from the lockdown. However, government initiatives have helped to minimize disruptions to pharmaceutical manufacturing and the supply chain, says GlobalData, a leading data and analytics company. The issues faced by the […]
Fujifilm’s influenza drug favipiravir being tested to treat COVID-19
As the number of confirmed COVID-19 cases reaches nearly 1.5 million worldwide, with almost 430,000 in the US alone, the urgency of finding a treatment mounts. One of the potentially quickest ways to find treatment is to test drugs already approved or in development for other indications, says GlobalData, a leading data and analytics company. Philipp Rosenbaum, PhD, Infectious Diseases Analyst at GlobalData commented: […]
Increased availability of virtual mental health tools reported as the COVID-19 crisis continues
Use of virtual mental health tools is expected to rise significantly over the coming months as self-quarantine and social distancing measures show no signs of being lifted, says GlobalData, a leading data and analytics company. Kathryn Whitney, MSc, Director of Thematic Analysis, comments: “COVID-19 has placed enormous strain on the mental health of the general public, as well as healthcare professionals. The crisis is causing heightened anxiety and stress, with people feeling vulnerable and struggling with worries about contracting the virus, job losses and pay […]
Novo Nordisk’s dominance in GLP-1RA market to continue with arrival of Rybelsus and strong sales for Ozempic in 2019
Novo Nordisk will continue to dominate a large share of the glucagon-like peptide-1 receptor agonist (GLP-1RA) market with the arrival of Rybelsus and Ozempic’s strong global sales of $1.65bn in 2019. This will enable the company to maintain its well-established position in the wider diabetes market, according to GlobalData, a leading data and analytics company. Akash Patel MSc, Pharma Analyst at GlobalData, comments: “Ozempic (semaglutide) is an injectable GLP-1RA indicated for the treatment of type 2 diabetes (T2D). Since its US launch in February 2018, the drug’s market share has grown due to its impressive glycemic and non-glycemic benefits. The drug also […]
Biomarkers heavily used as diagnostic tools in COVID-19 trials
Biomarkers are a beneficial tool in the search for a COVID-19 vaccine and will help speed up clinical trials, reduce costs of development, guide subject selection, reduce patient safety risks and allow for easier verification of the mechanism of action, says GlobalData, a leading data and analytics company. According to GlobalData’s Biomarkers database, the top […]
Novartis digital initiatives to create awareness of heart failure can positively impact patients’ lives in India, says GlobalData
Novartis has taken a lead in actively promoting heart failure awareness across India through unbranded digital initiatives that can successfully deliver message to a large population at risk, says GlobalData, a leading data and analytics company. According to GlobalData’s Pharma Intelligence Center, the diagnosed prevalence of congestive heart failure in India is currently around 9.61 […]
COVID-19 pandemic affects development of Alzheimer’s drugs
With many countries putting clinical trials studies on hold, pharmaceutical companies are shifting their overall priorities away from some current indications toward COVID-19. This could put several Alzheimer’s Disease (AD) drugs, of which there are 38 in Phase I, 19 in Phase III and 37 in Phase II, at risk of delay, says GlobalData, a leading data and […]
Remote clinical study Heartline well positioned to continue with minimal disruptions amid COVID-19
There has been an overall increase in clinical trials that have pushed back their estimated start dates since the beginning of January 2020, largely due to the COVID-19 pandemic. However, remote studies such as Heartline may have a significant advantage as patients can continue to enroll and participate from their homes. As such, the Heartline trial […]
Rheumatology patients treatment jeopardized by coronavirus pandemic
With the global COVID-19 pandemic, many patient groups are at an increased risk of infection and this extends to rheumatology patients prescribed immunosuppressant medication. The outbreak has presented these patients with medical and logistical difficulties that will certainly jeopardize their treatment, says GlobalData, a leading data and analytics company. Antoine Grey, MBiochem, Senior Healthcare Analyst […]
Nearly half of COVID-19 deaths among adults 80 years and older, says GlobalData
A comparison analysis of COVID-19 deaths from seven major markets (7MM*) shows disproportionate rates among older age groups says GlobalData, a leading data and analytics company. GlobalData epidemiologists compared COVID-19 mortality data by age groups from the 7MM and found that the proportions of deaths vary by older age groups in each market. The mortality analysis […]
AstraZeneca gains approval for Koselugo in rare neurological disorder after 17 years of development
Following the news that AstraZeneca’s Koselugo (selumetinib) has been approved by the US Food and Drug Administration (FDA) for the treatment of a rare neurological disorder; Philippa Salter, Neurology & Ophthalmology Analyst at GlobalData, a leading data and analytics company, offers her view: “Previous treatments for neurofibromatosis type 1 (NF1) in pediatric patients, who have […]
COVID-19 exposes fragility of global supply chains but blockchain could be missing link in building resilience, says GlobalData
The COVID-19 pandemic has disrupted nearly every part of supply chains within the healthcare industry, once again exposing the vulnerabilities of many organizations, especially those that have a high dependence on markets such as India and China to meet their raw materials or finished products’ needs. The COVID-19 outbreak is likely to result in healthcare […]
Clinical trials delayed during COVID-19, says GlobalData
There has been an increase in clinical trial delays due to concerns for patient and investigator safety, travel restrictions, subject quarantine, clinical site closures and interrupted supply chains. Numerous aspects of clinical trials are being impacted including enrolment of patients, study start times and initiation of new studies, says GlobalData, a leading data and analytics […]
Recently completed COVID-19 clinical trials show mixed results, says GlobalData
As the COVID-19 pandemic grows across the world, companies are beginning to accelerate their clinical trials for therapeutics and the number of trials has been growing. So far, 21 COVID-19 clinical trials have been completed – with the majority of those sponsored by Chinese hospitals and in the Wuhan province. As of yet, few outstanding […]
Gilead’s remdesivir better suited to mild-to-moderate COVID-19 patients, says GlobalData
Gilead Sciences’ remdesivir is more likely to work in mild-to-moderate COVID-19 patients rather than severe cases, according to reporting from Reynald Castañeda, Pharma Writer for the Investigative News team at GlobalData, a leading data and analytics company. Castañeda explains: “Given its antiviral mechanism, interviewed experts noted that remdesivir has the potential to decrease viral load in less-severe patients. […]
70% increase in clinical trial delays over the last 4 days due to COVID-19 disruption, says GlobalData
Following the news that the continual disruption caused by COVID-19 is starting to have an impact on the drug development programme timings of leading pharma companies; Sakis Paliouras, PhD, Oncology and Hematology Analyst at GlobalData, a leading data and analytics company, offers his analysis on the increase in delays in ongoing clinical trials: “According to […]
Italy likely reached COVID-19 transmission peak but total cases may reach over 200,000 before return to normal, says GlobalData
It is likely that Italy has reached a peak in COVID-19 transmissions as the country has seen a continued decrease in new laboratory-confirmed cases for the last two weeks. At the peak week, Italy was reporting an average of 5,500 new cases per day. Leading data and analytics company GlobalData’s COVID-19 modelling shows that while […]