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Following the publication, at the International Liver Congress (ILC) 2019, of top-line data from a proof-of-concept study into Gilead’s combination therapy for NASH; James Mather, MChem, Senior Pharma Analyst at GlobalData, a leading data and analytics company, offers his view on the impact these results could have on Gilead’s NASH pipeline: “As the race to […]
Gilead Sciences and Novo Nordisk NASH partnership will bolster growth for both companies
Following the news that Novo Nordisk and Gilead Sciences have partnered on a clinical trial combining drugs to treat the progressive fatty liver disease NASH, Kajal Jaddoo, Associate Analyst at GlobalData, a leading data and analytics company, offers her view: “Currently, treatment options for NASH are limited and populations are increasingly developing the disease fueled […]
World Parkinson’s Day 2019: Promising pipeline drugs could be key to tackling the disease and address unmet needs
In light of World Parkinson’s Day (11 April 2019), there have been a number of successes over the past half century in the treatment of Parkinson’s disease (PD) symptoms. However, key areas of unmet needs in the treatment of motor and non-motor symptoms still remain, says GlobalData, a leading data and analytics company. According to […]
Zogenix’s Fintepla projected to reach $872m by 2026 despite recent setback
The FDA recently rejected a marketing application for Zogenix’s Fintepla, an anti-epileptic drug candidate for Dravet syndrome. Magdalene Crabbe, Neurology and Ophthalmology Analyst at GlobalData, a leading data and analytics company, discusses the revelation: “The impact of this setback is not necessarily catastrophic. Fintepla is still at the pre-registration stage in the EU and in […]
Alnylam continues to blaze the RNAi frontier with Regeneron partnership
Following the news on April 8, 2019 that Alnylam and Regeneron have entered into an $800m pact to develop RNA interference (RNAi) therapies for eye and CNS diseases, Paul Jeng, Senior Pharma Analyst at GlobalData, a leading data and analytics company, offers his view on the growing opportunities for RNAi: “RNAi therapies are still relatively […]
Louisiana achieves major discount from Gilead’s subsidiary through Hepatitis C procurement model
Louisiana’s Department of Health recently announced that Gilead’s subsidiary Asegua Therapeutics has been selected as the pharmaceutical company for hepatitis C procurement model. Arafa Salam, PhD, Pharma Analyst at GlobalData, a leading data and analytics company, offers her view on the cost savings realized by this innovative procurement strategy: “The strong competition for patient share […]
UCB’s Cimzia US approval for nr-axSpA places company ahead of competitive biologic space
The approval of UCB’s Cimzia marks the first anti-tumor necrosis factor biologic therapy for non-radiographic axial spondyloarthritis (nr-axSpA) patients in the US, having been already approved for the condition in Europe. Antoine Grey, MBiochem, Immunology Analyst at GlobalData, a leading data and analytics company, offers his view: “UCB’s efforts to expand into a patient population […]
May’s third deal defeat heightens concerns within the UK’s healthcare sector
Following the PM’s third consecutive defeat on the original set date of Brexit, companies within the UK healthcare sector are in angst as the future of the country remains unclear. Gavin Davidson, Pharma Analyst at GlobalData, a leading data and analytics company, offers his views on the current events: “With a third defeat and multiple […]
Xeljanz cardiovascular safety signal unlikely to slow the upward trajectory of the JAK inhibitor class
On 20 March 2019, the European Medicines Agency (EMA) announced that it has put Pfizer’s blockbuster JAK inhibitor drug, Xeljanz (tofacitinib), under review following signs from a post-marketing study showing an increased risk of pulmonary embolism and overall mortality in rheumatoid arthritis (RA) patients who received a 10mg dose of Xeljanz twice daily, compared to […]
HeartMate 3 has potential to significantly impact treatment options for patients with end stage heart failure
Results posted from the MOMENTUM-3 clinical trial at the 68th American College of Cardiology Scientific Session on 17 March 2019, revealed that the HeartMate 3 LVAD demonstrated superiority over the HeartMate 2 LVAD in long-term treatment of end stage heart failure. David Brown, Medical Devices Analyst at GlobalData, offers his view: “The results of the […]
Sleep boosting DNA repair in damaged neurons could significantly impact the treatment of mental illnesses
A recent study conducted at Bar-Ilan University in Israel found that DNA repair in damaged neurons is most efficient during sleep, and treating sleep disorders is a vastly growing area of innovation in the pharmaceutical industry. Magdalene Crabbe, Neurology and Ophthalmology Analyst at GlobalData, a leading data and analytics company, discusses the revelation: “Considering the […]
The flow diversion stent market is growing at a CAGR of approximately 2%
Estimated to be approximately 15% of the embolization devices market, the flow diversion stent market is growing at a Compound Annual Growth Rate (CAGR) of approximately 2% by 2028, says GlobalData. In February, “Medtronic’s Pipeline Flex flow diversion device” won expanded FDA approval to treat small or medium wide-neck aneurysms, in addition to its existing […]
Despite two cases of remission, effective HIV cure is still years away
Following the news of a UK patient (The London Patient) who has been in remission with undetectable levels of HIV viral load for 18 months, becoming the second patient who has experienced disease free remission from HIV, Patrick Aiyes, MEng, Immunology Analyst at GlobalData, a leading data and analytics company comments: “The London Patient, similar […]
Tecentriq assumes pole position with FDA approval but Keytruda looms in triple negative breast cancer
On March 8, the FDA granted the accelerated approval of Roche’s programmed cell death protein 1 (PD-1) inhibitor Tecentriq in combination with Abraxane (protein-bound paclitaxel) for the treatment of locally advanced or metastatic triple-negative breast cancer (TNBC). Adam Pearson, PhD, Oncology and Hematology Analyst at GlobalData, a leading data and analytics company, offers his view […]
Apparent cure of a second HIV patient provides renewed hope for patients and researchers
Following the news that a UK patient has shown undetectable levels of HIV virus 18 months after after receiving transplanted stem cells from an HIV-resistant donor, representing the second case worldwide, following the Berlin patient’s apparent cure announced 10 years ago, Christopher Pace, PhD, Director of Infectious Diseases at GlobalData, offers his view: “The news […]
Novavax’s RSV vaccine fails second Phase III trial, further shrinking its pathways to success
Following the news on 28 February 2019 that Novavax’s respiratory syncytial virus (RSV) disease vaccine for infants – ResVax – did not meet its primary Phase III endpoint, Paul Jeng, PhD, Pharma Analyst at GlobalData, a leading data and analytics company, offers his view on the future prospects for ResVax in RSV prevention: “This is […]
Themis retains momentum for first Chikungunya vaccine approval with MV-CHIK
Following the news (25 February 2019) that the FDA has granted a Fast Track designation to Themis Bioscience’s lead Phase II experimental vaccine (MV-CHIK) for prevention of Chikungunya, Paul Jeng, PhD, Pharma Analyst at GlobalData, a leading data and analytics company, offers his view on the unmet needs and vaccine development for Chikungunya: “There are no […]
Roche’s acquisition of Spark Therapeutics is a long-term investment in the hemophilia A gene therapy market
Following the news (25 February 2019) that Roche has entered into a definitive merger agreement to fully acquire Spark Therapeutics for $4.3bn, Tajekesa Chapman, Pharma Analyst at GlobalData, a leading data and analytics company, offers her view on the acquisition: “The hemophilia market is currently undergoing major changes in its treatment landscape due to advances […]
Neurofilament light is most promising molecule for use in routine management of patients with MS
Following the news (20th February 2019) that, according to a study published in the journal Neurology, blood neurofilament light chain can be a biomarker of multiple sclerosis (MS) disease activity and treatment response, Alessio Brunello, Pharma Analyst at GlobalData, a leading data and analytics company, offers his view: “Finding a biomarker in MS that translates […]
Merck’s Keytruda set to become new standard of care for renal cancer patient population after gaining edge over competitors
Merck & Co Inc’s abstract presentation regarding KEYNOTE-426 trial at ASCO GU 2019 (16 February 2019) has confirmed that Keytruda, an anti-PD-1 therapy, in combination with Pfizer’s Inlyta, a tyrosine kinase inhibitor, can significantly improve clinical outcomes for renal cancer patients. Amrita Gujral, Pharma Analyst at GlobalData, a leading data and analytics company, offers her […]