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The biopharmaceutical industry is showcasing increasing optimism regarding its growth prospects over the next 12 months. While the upward trend is a positive sign, it remains below the levels of confidence seen in 2022, finds GlobalData, a leading data and analytics company. In a recent GlobalData’s survey*, “The State of the Biopharmaceutical Industry 2024 (mid-year […]
Biopharmaceutical industry remains mixed over EU reform proposals, finds GlobalData
Reforms to the European Union’s (EU) general pharmaceutical legislation emerge as one of the key policy developments affecting the operating environment for the pharma industry. In a survey, respondents’ opinions on the impact of EU reform proposals were mixed, with the percentage of participants expressing positive, negative, or neutral views remaining varied, according to GlobalData, […]
Amylyx’s efforts to explore other indications for Relyvrio seem to be bearing fruit, says GlobalData
In March 2024, Amylyx Pharmaceuticals announced that Relyvrio, a neuroprotective agent, failed to achieve its primary efficacy endpoints in the global Phase III PHOENIX trial for amyotrophic lateral sclerosis (ALS). Relyvrio/Albrioza was first approved in the US and Canada in September 2022 for the treatment of ALS. However, following the monumental setback, on April 4, […]
ADHD market to decline by over $900 million in 7MM during 2022-32, forecasts GlobalData
The attention-deficit/hyperactivity disorder (ADHD) market across the seven major markets (7MM*) is forecast to decline at a negative compound annual growth rate (CAGR) of 0.8% from $11.9 billion in 2022 to $11.0 billion in 2032, driven by patent expiries, high generic uptake in the largest ADHD market, namely the US, and limited innovator entrants, according […]
PROTACs oncology market to hit $3.7 billion by 2030 despite lack of approved therapies, says GlobalData
Proteolysis targeting chimeras (PROTACs) are a promising approach to cancer treatment, yet after over two decades of research, not a single PROTAC has gained FDA approval. PROTACs are novel bifunctional compounds that promote the degradation of a protein of interest (POI) by connecting a POI ligand to an E3 ubiquitin ligase (E3) ligand through a […]
IGNAZ trial interim results highlight HI-Bio’s potential to differentiate in IgAN space, says GlobalData
At this year’s European Renal Association, positive results were presented from Human Immunology Bioscience’s (HI-Bio) interim results of the Phase II IGNAZ clinical trial. According to the results, the use of MOR-202 (felzartamab) demonstrated a deep and durable reduction in proteinuria in patients with immunoglobulin A (IgA) nephropathy (IgAN). The drug potentially fills an unmet […]
Neurology remains key therapeutic area for Japan pharma majors, says GlobalData
In the dynamic landscape of healthcare, key neurological disorders like Alzheimer’s disease, epilepsy, Parkinson’s disease, and depression pose significant challenges, particularly in the Asia-Pacific (APAC) region, where prevalence is high. The World Health Organization stated in March 2024 that “over 80% of neurological deaths and health losses occur in low- and middle-income countries, and access […]
Verona’s Ensifentrine attracts positive opinions in light of anticipated US launch for COPD, says GlobalData
Verona Pharma recently announced that they are finalizing preparations for a potential US launch of Ensifentrine in the third quarter of 2024, depending upon the FDA’s approval, set for June 26, 2024. The first-in-class dual phosphodiesterase (PDE) 3/4 inhibitor aims to reduce exacerbations in chronic obstructive pulmonary disease (COPD) patients, administered as a nebulized formulation. […]
Osteoporosis Awareness & Prevention Month highlights need for prioritizing early diagnosis and advanced treatments, says GlobalData
The Bone Health and Osteoporosis Foundation (BHOF) observes the month of May every year as Osteoporosis Awareness & Prevention Month to shed light on the critical needs of those living with osteoporosis. Advocates emphasize the importance of enhancing education, research, and healthcare strategies to tackle this prevalent, yet frequently neglected condition. Prioritizing prevention, early diagnosis, […]
AbbVie’s strong immunology portfolio to offset Humira losses, says GlobalData
For 20 years, AbbVie’s Humira (adalimumab) has been one of the world’s top-selling products. However, the US drug expiry in January 2023 resulted in a 32% decline in sales of Humira in 2023, accompanied by a 7% drop in the company’s total revenue for that year. As further sharp declines are expected for Humira, AbbVie […]
Total prevalent cases of osteoporosis to surpass 58.05 million in 7MM in 2033, forecasts GlobalData
The total prevalent cases of osteoporosis in the seven major markets (7MM*) are projected to increase from 51.17 million in 2023 to 58.05 million in 2033, with an annual growth rate (AGR) of 1.34%, forecasts GlobalData, a leading data and analytics company. GlobalData’s latest report, “Osteoporosis – Epidemiology Analysis and Forecast to 2033,” reveals that […]
Innovent Biologics mazdutide can pave way for transformative T2D treatment, says GlobalData
Innovent Biologics Inc has recently unveiled promising Phase III (DREAMS-2) results for mazdutide, indicating superiority over dulaglutide in glycaemic control for type 2 diabetes (T2D) patients in China. With its potential to revolutionize T2D treatment, mazdutide’s success could not only reshape the landscape of diabetes therapeutics in China but also underscores the growing demand for […]
Non-injectable medication development remains significant unmet need in female infertility, says GlobalData
Great progress has been made in the management of female infertility since the introduction of assisted reproductive technology, predominantly in vitro fertilization (IVF). However, despite the improvements made in the space, challenges associated with the treatment remain. The development of non-injectable fertility medications represents a significant unmet need, according to key opinion leaders (KOLs) interviewed […]
Pre-emptive pandemic preparedness measures emerge in US against avian influenza A(H5N1), says GlobalData
With cases of avian influenza A(H5N1) on the rise among cattle in the US, government health officials are preparing for the potential of the virus adapting to enable human-to-human transmission and have two vaccine candidates available in case of such an event. While there is no evidence yet that H5N1 could spread between humans, such […]
World AIDS Vaccine Day 2024: Prophylactic vaccines in phase II development hold potential to reduce epidemic burden, says GlobalData
World AIDS (acquired immunodeficiency syndrome) Vaccine Day, also known as HIV (human immunodeficiency virus) Vaccine Awareness Day, takes place annually on 18 May. The National Institute of Allergy and Infectious Diseases (NIAID) leads the observance, educating the public on the importance of HIV prevention and the significance of vaccine research, and acknowledging the contributions of […]
AstraZeneca’s Fasenra approval for asthma could have same potential for COPD, says GlobalData
AstraZeneca’s Fasenra (benralizumab) recently received Food and Drug Administration (FDA) approval for severe asthma in children aged 6 to 11, specifically for the eosinophilic phenotype, in over 80 countries, including the US, EU, and Japan. Fasenra is a monoclonal antibody intended to inhibit the alpha subunit of the interleukin-5 receptor found on eosinophils and is […]
GLP-1R agonists’ type 2 diabetes and obesity market to reach $125 billion in 7MM by 2033, forecasts GlobalData
Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of incretin mimetic medicines for the treatment of type 2 diabetes and obesity. With the obesity and type 2 diabetes markets growing at unprecedented rates, the GLP-1 receptor agonists market is also growing. GLP-1 receptor agonist sales for the type 2 diabetes and obesity markets are forecast […]
Roche challenges Regeneron and Bayer’s position as industry leaders within wAMD, DME and DR spaces, says GlobalData
Roche’s Vabysmo (faricimab) is in the spotlight following its promising Q1 2024 sales figures. Vabysmo, a vascular endothelial growth factor (VEGF) inibitior and angiopoietin-2 (Ang-2) inhibitor therapy, is indicated for wet age-related macular degeneration (wAMD), diabetic macular edema (DME), and macular edema following retinal vein occlusion (RVO). This presents a looming challenge to Regeneron and […]
Anticipation builds as Insmed bronchiectasis therapy brensocatib nears Phase III completion, observes GlobalData
Insmed is in the spotlight over the past few years for its pipeline agent, brensocatib, which has previously shown promising Phase II results, generating anticipation within the medical community ahead of their Phase III results for the treatment of bronchiectasis. The positive outcomes could pave the way for regulatory approval, potentially transforming the therapeutic landscape […]
Diagnosed incident cases of HER2-positive breast cancer to grow at 1.5% AGR between 2023-2033 across 8MM, forecasts GlobalData
The diagnosed incident cases of HER2-positive (HER2+) breast cancer in the eight major markets (*8MM) are projected to increase from 107,352 in 2023 to 123,580 in 2033 for invasive HER2+/HR+ breast cancer, and from 59,598 cases in 2023 to 68,846 cases in 2033 for invasive HER2+/HR- breast cancer, at an annual growth rate (AGR) of […]