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Despite the continued success of prophylactic vaccines such as Pfizer/BioNTech’s messenger RNA (mRNA) vaccine Comirnaty and spikes in COVID-19 case numbers over the winter, prophylactic COVID-19 vaccine sales forecasts have seen an average decline between H1 2022 and H2 2022 of 7% in their predicted total forecast sales between 2022 and 2028, says GlobalData, a […]
Janssen and Eli Lilly collaboration to address lack of pediatric therapies could rescue mirikizumab program, says GlobalData
In recent years, there has been a steady increase in the number of agents approved to treat inflammatory bowel diseases (IBD), which has provided physicians with an increasing number of options to treat Crohn’s disease (CD). However, this progress is not reflected in the number of approved treatments for pediatric IBD patients. Of the seven […]
Zynerba’s Zygel could target Fragile X Syndrome but likely to face barriers in uptake, says GlobalData
There are currently no approved therapies available for Fragile X Syndrome (FXS), with prescribed treatments consisting exclusively of off-label drugs that target individual symptoms of the disease. However, as these therapies do not target the pathogenesis underlying FXS, they have only a modest effect on a subset of patients. This has led to a call […]
GlobalData slashes Moderna COVID-19 vaccine Spikevax sales forecast amid strong competition
It was an exceptional year for Moderna’s vaccine Spikevax, with forecast sales of $19.5 billion in 2022. However, increasing competition from Pfizer’s Comirnaty, Novavax’s Nuvaxovid, and COVID-19 therapeutics has forced GlobalData to slash Spikevax’s average annual sales forecast by 23% between H1 and H2 2022 in its Coronavirus Disease 2019 (COVID-19) Sector Forecast reports. Kevin […]
Uptake of long-awaited Humira biosimilar in US to be dictated by price, says GlobalData
Following the launch of Amgen’s Amjevita (adalimumab-atto), the first biosimilar to AbbVie’s cash-cow immunology biologic therapy, Humira (adalimumab), in the US on 31 January; Vinie Varkey, Managing Analyst, Immunology at GlobalData, a leading data and analytics company, offers her view: “For AbbVie, while the threat of adalimumab biosimilars to its blockbuster therapy are finally tangible […]
With expanded approval for Brukinsa, BeiGene poised to lead chronic lymphocytic leukemia market, says GlobalData
The FDA has recently granted expanded approval for BeiGene’s oral Bruton tyrosine kinase inhibitor (BTKi) Brukinsa (zanubrutinib) for patients with chronic lymphocytic leukemia (CLL) or small Lymphocytic Leukemia (SLL). Brukinsa has gained approval after outperforming Abbvie’s Imbruvica, which has been the standard of care in CLL for almost a decade. Brukinsa should largely replace Imbruvica […]
Biomarker identification important for the future of ulcerative colitis treatment, says GlobalData
Inflammatory bowel disease (IBD) refers to two autoimmune diseases that cause intestinal inflammation: Crohn’s disease (CD) and ulcerative colitis (UC). The market for the UC is filled with several different treatment options, and the pipeline is relatively strong. Despite this, there remains an unmet need due to the unpredictable nature of UC. As a result, […]
AI and Big Data will be most impactful emerging technologies for pharma industry in 2023, finds GlobalData survey
Artificial Intelligence (AI) and Big Data will be the two most impactful technologies for the pharmaceutical industry for the fourth year in a row in 2023, according to a survey by GlobalData. The leading data and analytics company notes that 39% of healthcare industry professionals in the survey believed that AI would be the emerging […]
CAR-T cells to hold over 40% of acute lymphocytic leukemia market by 2031, forecasts GlobalData
The market for acute lymphocytic leukemia (ALL), the most commonly diagnosed form of leukemia, is expected to see strong growth at a compound annual growth rate (CAGR) of 5% over the next decade across the world’s eight major markets (8MM*). This is driven primarily by the increased use of cell therapies, with the CAR-T market […]
Takeda newly approved NSCLC therapy Exkivity still has room for better treatment outcome in China, observes GlobalData
Takeda‘s Exkivity (mobocertinib) is the first and only targeted therapy to be approved for locally advanced or metastatic epidermal growth factor receptor (EGFR) exon 20 insertions (exon20ins)-positive non-small cell lung cancer (NSCLC) in China. The drug is approved under the National Medical Products Administration’s Breakthrough Therapy program for second-line treatment. However, there still exists room […]
Pharma companies that develop vaccines with efficacy against Omicron variants will gain competitive advantage in China, says GlobalData
Omicron lineages BA.5.2 and BF.7 account for 97.5% of all local infections in China, according to the Chinese Center for Disease Control and Prevention. With new cases spreading rapidly, the National Health Commission (NHC) announced a national fourth booster vaccination campaign. Consequently, Chinese vaccine developers are focused on expanding their COVID-19 pipelines to include targeted […]
Intercept Pharmaceuticals’ obeticholic acid could be first drug to be approved for NASH, says GlobalData
Intercept Pharmaceuticals’ obeticholic acid could be first drug to be approved for NASH, says GlobalData Following FDA’s acceptance for Intercept Pharmaceuticals’ resubmission of its new drug application (NDA) for obeticholic acid (OCA) in patients with pre-cirrhotic liver fibrosis due to non-alcoholic steatohepatitis (NASH) in December 2022 Sravani Meka, Senior Immunology Analyst at GlobalData, a leading […]
Obesity therapy by Versanis Bio sees advantageous MoA and reduced treatment days but challenged by pricing and hospital administration, says GlobalData
Following Versanis Bio’s recent announcement that enrolment had begun for Phase IIb trial BELIEVE on bimagrumab (BYM338); Sara Reci, Pharma Analyst at GlobalData, a leading data and analytics company, offers her view: “Bimagrumab has the potential to address key unmet needs in the obesity space. One advantage is its novel mechanism of action (MoA). Currently, […]
89bio’s pegozafermin has potential to become a major player in the dyslipidemia market, says GlobalData
89bio’s pegazofermin has potential to become one of the major players in the dyslipidemia space if it is successful in Phase III clinical trials, says GlobalData, a leading data and analytics company. The Food and Drug Administration (FDA) recently supported the advancement of pegozafermin into two Phase III clinical trials, the first due to launch […]
Genetic map of cells linked to endometriosis could help to improve treatment options, says GlobalData
Following the news that scientists at Cedars-Sinai have successfully mapped the cellular changes linked to endometriosis; Amy Murray, Healthcare Analyst at GlobalData, a leading data and analytics company, offers her view: “Despite its high prevalence and cost, endometriosis remains an understudied disease. This lack of research has greatly limited understanding and slowed much-needed innovation in treatment […]
Leqembi’s prospects in the Alzheimer’s disease market remain uncertain despite its advantages over Aduhelm, says GlobalData
Eisai and Biogen’s anti-amyloid beta (Aβ) monoclonal antibody (mAb), Leqembi (lecanemab), recently gained approval from the Food and Drug Administration (FDA) under the accelerated approval pathway for the treatment of Alzheimer’s disease (AD) in patients with early AD. Achieving full approval will be crucial for Leqembi’s prospects as the US Centers for Medicare and Medicaid […]
Healthcare industry professionals’ optimism regarding pharma industry’s growth prospects is fading, finds GlobalData
The pharmaceutical industry is considered to be one of the most stable sectors even when pandemics, economic or geopolitical crises hit markets. However, even the pharmaceutical industry is not immune to the uncertainty in business conditions that 2023 may bring, finds GlobalData, a leading data and analytics company. A survey* taken from GlobalData’s report, ‘The State of the Biopharmaceutical Industry […]
Global (68M) cardiomyopathies market set to reach $9.63 billion by 2031 driven by US and China’s drug sales, forecasts GlobalData
The cardiomyopathies market in the 68M* is set to grow from $3.07 billion in 2021 to $9.63 billion in 2031 at a compound annual growth rate (CAGR) of 12.1%, notes leading data and analytics company GlobalData. GlobalData’s research reveals that North America accounted for 51.7% of cardiomyopathy drug sales in the 68M in 2021 and […]
T2D market will reach $136.2 billion in 2029 driven by the launch of novel GLP-1s and once-weekly basal insulin therapies, says GlobalData
Type 2 diabetes (T2D) is a crowded and competitive landscape with multiple ‘me-too’, generic and biosimilar drugs entering the market. Growth will be primarily driven by the launch of novel blockbuster therapies and an increasing diagnosed prevalent population across the nine major markets (9MM)*, notes GlobalData, a leading data and analytics company. According to GlobalData’s latest […]
Western companies to play key role in improving cardiovascular disease management approach in China, says GlobalData
Cardiovascular diseases (CVDs) continue to be the leading cause of death globally, with China being no exception. As domestic companies are mostly involved in providing generic drugs for CVDs, China is heavily reliant on foreign players. Against this backdrop, key foreign players will play a crucial role in improving the overall cardiovascular disease management approach […]