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With rising inflation and a cost-of-living crunch in the US, the passing of the $740 billion Inflation Reduction Act of 2022, which aims to control and lower prescription drug costs, will be welcome news for patients on a budget. However, although its full effects will not be felt until 2026, few pharma companies will be […]
Axsome Therapeutics’ Auvelity will experience strong uptake globally by 2029 and reach $1.3 billion sales, forecasts GlobalData
Following the news that Axsome Therapeutics’ Auvelity (dextromethorphan + bupropion) has been approved by the FDA for the treatment of major depressive disorder (MDD) in adults; Pippa Salter, Senior Neurology Analyst at GlobalData, a leading data and analytics company, offers her view: “Auvelity’s rapid onset of action will provide a major breakthrough to the MDD […]
Alnylam identifies gene target for potential novel therapy for cardiovascular and metabolic disorders, says GlobalData
Alnylam Pharmaceuticals and its partners have identified rare mutations in the INHBE gene that is expressed in the liver and related to a lower waist-to-hip ratio for body mass index (BMI) reducing the likelihood of many major metabolic disorders. With such high levels of interest preventing metabolic disorders, it is likely that a drug which […]
Growing investment in biotech startups likely to make CAR-T therapies affordable in India, says GlobalData
Biotech startups in India, which are focused on developing cell/gene (including CAR-T) therapies for the management and treatment of certain life-limiting illnesses that significantly affect the patient’s quality of life, are increasingly attracting investment from major pharmaceutical companies. This is likely to boost their research and production capabilities and eventually makes the therapies affordable to […]
Karuna’s KarXT could have a major competitive edge for schizophrenia treatment, says GlobalData
Karuna Therapeutics recently announced positive topline results from the Phase III EMERGENT-2 trial of KarXT (xanomeline + trospium chloride) in acutely psychotic hospitalized adult patients with schizophrenia. According to GlobalData, if KarXT continues to show success within the EMERGENT trial program as a monotherapy, as well as in the ongoing ARISE trial as an adjunctive to traditional antipsychotics, […]
Ulcerative colitis treatment pipeline flush with promising therapies, says GlobalData
The ulcerative colitis (UC) treatment pipeline is flush with promising therapies, with over 13 agents in either Phase IIb or III development. Many of these agents are in the later stages of development and have promising novel mechanisms of action (MOAs) and new routes of administration, which will ultimately provide more treatment options for patients […]
Coherus’ Cimerli to Fuel Competition in Anti-VEGF Biosimilar Market Within DME Space, says GlobalData
On August 2, the Food and Drug Administration (FDA) announced the approval of Coherus’ Cimerli (ranibizumab-eqrn; FYB201), which demonstrated efficacy and safety results parallel to its reference product, Roche’s Lucentis (ranibizumab). This approval is of paramount interest as Cimerli is the first anti-VEGF biosimilar in the Diabetic Macular Edema (DME) space to gain a 12-month […]
Long-acting injectables remain under-utilized for schizophrenia in 7MM despite benefits, says GlobalData
Long-acting injectable (LAI) formulations of antipsychotics to treat patients diagnosed with schizophrenia remain under-utilized in the seven major markets (7MM*) due to the resistance surrounding the use of these products despite the benefits, says GlobalData, a leading data and analytics company. According to GlobalData, patients tend to continue oral antipsychotic treatment, and this results in […]
Improved irritability treatments and novel treatments for ASD core symptoms are most important unmet needs in ASD market in 7MM, finds GlobalData
Improved treatments options for irritability and novel treatments for core symptoms of autism spectrum disorder (ASD) are the most important unmet needs in the ASD market in the seven major markets (7MM*), finds GlobalData, a leading data and analytics company. A recent survey** by GlobalData has revealed that treatment options to target irritability and aggression […]
Diagnosed prevalent cases of diabetic macular edema to reach two million in 2031 across 7MM, says GlobalData
The diagnosed prevalent cases of diabetic macular edema (DME) in the seven major markets (*7MM) are projected to increase from 1.7 million cases in 2021 to 2 million in 2031, equating to an annual growth rate (AGR) of 1.66%, according to GlobalData, a leading data and analytics company. DME is a condition characterized by the […]
Diagnosed prevalent cases of primary myelofibrosis in China set to increase by 34.8% between 2021 and 2031, forecasts GlobalData
The diagnosed prevalent cases of primary myelofibrosis (PMF) in China are expected to increase by 34.8% between 2021 and 2031, according to GlobalData, a leading data and analytics company. GlobalData’s latest report, ‘Myelofibrosis Epidemiology Analysis and Forecast, 2021-2031’, notes that the major drivers for the spike in the diagnosed prevalent cases of PMF in China […]
Advancements in GA pipeline bring first wave of therapies closer to patients, says GlobalData
Following the results from Apellis Pharmaceuticals’ Phase III ‘DERBY and OAKS’ study of APL-2 and the post hoc analysis from IVERIC BIO’s Phase III GATHER 1 clinical trial for Zimura, which provided a positive outlook for geographic atrophy (GA) patients by demonstrating clinically significant reduction in lesion growth, leading data and analytics company GlobalData highlights […]
Age-related macular degeneration market across 7MM to reach $22.8 billion in 2031, forecasts GlobalData
The age-related macular degeneration (AMD) market in the seven major markets (7MM: the US, France, Germany, Italy, Spain, the UK, and Japan) is set to grow from $7.3 billion in 2021 to $22.8 billion in 2031, driven by the longer-acting anti-vascular endothelial growth factor (VEGF) pipeline therapies as well as potentially first-to-market therapies for geographic […]
12-month diagnosed prevalent cases of schizophrenia across 7MM to reach 3.49 million in 2031, forecasts GlobalData
The 12-month diagnosed prevalent cases of schizophrenia are expected to increase from 3.40 million in 2021 to 3.49 million in 2031 across the seven major markets (7MM*), at an annual growth rate (AGR) of 0.26%, forecasts GlobalData, a leading data and analytics company. GlobalData’s latest report, ‘Schizophrenia Epidemiology Analysis and Forecast, 2021-2031’, reveals that the […]
Monkeypox outbreak must be taken seriously by public health officials, as new methods of viral spread have recently emerged, says GlobalData
Following the news that the World Health Organization (WHO) has declared the monkeypox outbreak a Public Health Emergency of International Concern (PHEIC); Nancy Jaser, PharmD/MBA, Pharma Analyst at GlobalData, a leading data and analytics company, offers her view: “Recent changes to the mode of transmission and disease presentation of monkeypox in the current outbreak are […]
Homegrown SKYCovione will strengthen South Korea position in global COVID-19 vaccine industry, says GlobalData
SK Bioscience has recently announced that South Korea’s first homegrown COVID-19 vaccine ‘SKYCovione’ adjuvanted with GlaxoSmithKline’s pandemic adjuvant has been authorized by the Korean Ministry of Food and Drug Safety (KMFDS). This will not only strengthen the country’s overall position in the global vaccine industry but also reduce its reliance on foreign vaccines, says GlobalData, […]
Gene therapy RGX-314 holds potential for diabetic macular edema treatment, says GlobalData
AbbVie/Regenxbio recently presented data from a Phase II study of its lead diabetic retinopathy (DR) and neovascular age-related macular degeneration (nAMD) gene therapy candidate, RGX-314, at the American Society of Retinal Specialists (ASRS) annual meeting, which took place on July 13-16. RGX-314 has the potential to address a key unmet need for drugs that reduce patient […]
Detection of world’s second-deadliest cancer being caught at earlier stages worldwide in 2021, says GlobalData
Research by GlobalData has revealed that the majority of colorectal cancer (CRC) cases were detected at stages I and II in 2021, despite the patient showing no symptoms of the disease at these stages. The leading data and analytics company notes that this data suggests that screening programs, as well as the promptness in which […]
Top-selling COVID-19 drug Paxlovid could see sales decrease from 2023 following second booster, says GlobalData
Although many pharmaceutical companies have launched therapeutic drugs for COVID-19, Pfizer’s Paxlovid takes the top spot as market leader. The drug has expected peak sales of $30.7 billion in 2022 and total generated sales of $81 billion between 2021 and 2028, according to GlobalData, a leading data and analytics company. Paxlovid is an oral small […]
Diagnosed prevalent cases of age-related macular degeneration in France projected to increase by 28.95% between 2021 and 2031, says GlobalData
Diagnosed prevalent cases of age-related macular degeneration (AMD) in the seven major markets (7MM*) combined is expected to increase from 33.66 million cases in 2021 to 40.32 million in 2031, at an annual growth rate (AGR) of 1.98%, according to GlobalData, a leading data and analytics company. AMD is a progressive eye condition that is […]