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Increasingly, over the past decade pharmaceutical companies have sought to enhance the efficacy of Immune checkpoint inhibitors (ICIs) by using these in combination with other ICIs, chemotherapies, small molecules or cell therapies says GlobalData, the leading data and analytics company. ICIs are very widely used in oncology and include blockbuster drugs Merck & Co.’s Keytruda […]
Novel CAR-T cell approaches of Chinese pharma promote clinical innovation and can address remaining unmet needs, says GlobalData
Chinese pharma companies are continuously focusing on the research and development of new innovative oncology therapies. Recently, Innovent Biologics and Gracell Biotechnologies have initiated Phase I trials for their innovative chimeric-antigen receptor T (CAR-T) therapies. It could further address remaining unmet needs, says GlobalData, a leading data and analytics company. Gracell Biotechnologies’ GC012F is developed […]
AML treatment landscape in China evolving with availability of multiple precision therapy options, says GlobalData
China has recently approved CStone Pharmaceuticals’ Tibsovo (ivosidenib tablets) for the treatment of adult patients with relapsed/refractory acute myeloid leukemia (R/R AML) with a susceptible isocitrate dehydrogenase-1 (IDH1) mutation, providing a new precision therapy for this patient population. With multiple precision therapies now available, the cancer treatment arsenal is expanding for adult acute myeloid leukemia […]
Evelo’s EDP-1815 to initiate Phase III trial by Q4 2023, predicts GlobalData
GlobalData anticipates that Evelo Biosciences’ Phase III study of EDP-1815 for the treatment of psoriasis (PsO) will be initiated in Q4 2023. The leading data and analytics company notes that EDP-1815 has been the company’s most progressed candidate, as it is currently in late-stage development for plaque PsO and COVID-19, and is in Phase II […]
Early results highlight ZT-01’s ability to restore glucagon regulation in type 1 diabetics, says GlobalData
Zucara Therapeutics recently announced the publication of ZT-01 preclinical data for the treatment of insulin-induced hypoglycemia in patients with type 1 diabetes (T1D). Zucara is currently conducting a Phase 1b proof-of-concept clinical trial in people with T1D, with results anticipated in Q2 2022. With few therapeutics in development that focus on hypoglycemic prevention specifically, GlobalData […]
Ardelyx’s tenapanor has potential to capture a slice of the CKD-HP market, says GlobalData
Ardelyx’s tenapanor has the potential to capture a slice of the chronic kidney disease (CKD)-hyperphosphatemia (HP) market if the company can successfully appeal the Food and Drug Administration’s Appeal Denied Letter (ADL), says GlobalData. The leading data and analytics company notes that tenapanor’s potential is based on its ability to target dialysis-dependent patients who are […]
Novartis’ Leqvio has potential to lead the cholesterol-lowering space due to its administration convenience, says GlobalData
Sales for Novartis’ Leqvio (inclisiran) for the treatment of high cholesterol may surpass those of Sanofi/Regeneron’s Repatha (evolocumab) and Amgen’s Praluent (alirocumab) by 2027 due to its administration convenience, according to GlobalData. The leading data and analytics company notes that Leqvio is in a better position compared to its competitors as it is administered by […]
The trauma fixation market will reach $5.9 billion by 2030 due to improving patient outcomes, says GlobalData
Trauma fixation devices are considered to be the essential first-line treatment for bone fractures. According to GlobalData analysis, the trauma fixation market is valued at $5.3 billion in 2021 and will reach $5.9 billion in 2030, with a Compound Annual Growth Rate (CAGR) of 1.3% from 2021 to 2030. According to GlobalData’s market model, ‘Trauma […]
Despite launch of seven pipeline agents, bipolar disorder market will see only modest growth due to persistent generic erosion, says GlobalData
The bipolar disorder market is expected to grow from $4.1 billion in 2020 to $4.9 billion by 2030 across the eight major markets (8MM*) at a compound annual growth rate (CAGR) of 1.7%, according to GlobalData, which notes that the main driver of growth will be the launch of seven new pipeline products throughout the […]
GlobalData partners with Snowflake to empower seamless access and delivery of its data
GlobalData’s Marketplace is now accessible via Snowflake’s cloud data platform, empowering seamless access and direct integration of GlobalData’s intelligence into customer applications and data operations. London – February 21, 2022 – GlobalData Plc (LSE: DATA), a leading intelligence platform for the world’s largest industries, has announced a partnership with Snowflake, a premier data warehouse built […]
Promising pipeline drugs to transform the Fragile X Syndrome treatment market by 2030, says GlobalData
By 2030, GlobalData highlights that promising pipeline drugs Zygel, zatolmilast, trofinetide, and acamprosate calcium SR are set to offer new treatment options for people with Fragile X Syndrome (FXS)—a rare genetic disorder that is the leading cause of inherited intellectual disability. The leading data and analytics company notes that these products will help propel the […]
Haplo-cord treatment may provide permanent cure for over 37.7 million HIV sufferers, says GlobalData
Following the recent news that the woman referred to as ‘the New York patient’, who received haplo-cord treatment four years ago, is now off HIV medication and remains asymptomatic and healthy: Sultan Ahmed, Infectious Disease Analyst at GlobalData, a leading data and analytics company, offers his view: “The haplo-cord transplant, conventionally used for cancer treatment, […]
Global chronic myeloid leukemia market set to decline due to most medication losing patent protection by 2030, says GlobalData
The chronic myeloid leukemia (CML) therapy market is dominated by tyrosine kinase inhibitors (TKIs) targeting aberrant BCR-ABL1. However, with all but one of the currently marketed BCR-ABL1 TKIs due to lose patent protection by 2030, the global market is set to decline from $4.25 billion in 2020 to $3.35 billion in 2030, says GlobalData. According […]
Diagnosed incident cases of cervical cancer in urban China to rise by 1.90% AGR during 2020-30, forecasts GlobalData
Due to lack of HPV vaccination program, the diagnosed incident cases of cervical cancer in urban China are expected to increase at an annual growth rate (AGR) of 1.90% between 2020 and 2030. China is followed by the US (0.78%), and the UK (0.34%), finds GlobalData, a leading data and analytics company. However, diagnosed incident […]
Anavex’s therapy for Rett syndrome shows promise, but questions remain over clinical trial endpoints, says GlobalData
The potential Food and Drug Administration (FDA) acceptance of Anavex Life Sciences’ AVATAR as a pivotal Phase III trial would have an important bearing on the Rett syndrome market, as it could enable blarcamesine to launch at a similar time as Neuren Pharmaceuticals’ trofenitide, which is a major future competitor, says GlobalData, a leading data […]
Delay in launch of indigenous COVID-19 vaccines by Japanese pharma will impact domestic market potential, says GlobalData
Pharma companies in Japan are still working to bring their first COVID-19 indigenous vaccine, though the pandemic has already completed two years in various parts of the world. As a result, any further delay in the launch of indigenous COVID-19 vaccines will impact domestic market potential, says GlobalData, a leading data and analytics company. According […]
GlobalData sees significant gap in digital marketing for obesity in Australia
Obesity is a key public health concern and a leading risk factor for other lifestyle-related illnesses in Australia. Currently, four key pharma companies offer marketed therapies for the treatment of obesity. However, digital support is limited to just Novo Nordisk and iNova Pharmaceuticals. Against this backdrop, other key players in Australia’s obesity market have significant […]
AI together with Big Data will be the most disruptive emerging technology duo in the pharmaceutical sector in 2022, says GlobalData
Despite being years away from exhibiting its full potential, artificial intelligence (AI), together with Big Data, stand out as a versatile combination to address challenges faced by the entire pharmaceutical value chain, says GlobalData, a leading data and analytics company. In GlobalData’s latest report, ‘The State of the Biopharmaceutical Industry – 2022’, AI, followed by […]
Takeda’s decision to terminate Eohilia opens the EoE market for other drugs in the pipeline, says GlobalData
Takeda’s decision to cease further support to launch Eohilia (for patients ages 11 years and above) to the eosinophilic esophagitis (EoE) market will result in the continued use of off-label proton pump inhibitors and corticosteroids in the first and second line of therapies. However, the termination of Eohilia is not expected to have any impact […]
Drug pricing and reimbursement-related concerns will remain the leading impediment to the pharmaceutical industry’s growth in 2022, says GlobalData
Drug pricing pressures will continue to hinder the growth of the pharmaceutical industry in 2022, forcing companies to reassess their pricing strategies and market focus, says GlobalData, a leading data and analytics company. In GlobalData’s latest report, ‘The State of the Biopharmaceutical Industry – 2022’, drug pricing and reimbursement constraints elicited the strongest responses from […]