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National Colorectal Cancer (CRC) Awareness Month is an opportunity to raise awareness about the disease and educate patients, especially about recurrence, one of the most important factors influencing survival. According to GlobalData, a leading data and analytics company, liquid biopsy could be one of the main technique to test for CRC recurrence as these tests […]
Addressing ESG issues may help pharma to repair its reputation
As pharmaceutical companies continue to grapple with issues ranging from lack of transparency on pricing, price gouging to questionable ethical practices and clinical data reporting processes, addressing environmental, social, and governance (ESG) issues will continue to be an important, and perhaps beneficial theme for the industry in 2021, says GlobalData a leading data and analytics company. In a recent GlobalData poll* it was highlighted that environmental issues were viewed as the most important ESG area […]
Bio/Pharma companies’ Q4 2020 market performance impacted by development of treatments or vaccines for COVID-19
The market performance of the top 20 Bio/Pharma companies is still being impacted by the COVID-19 pandemic, either positively for companies developing a vaccine for the disease or negatively for those working on a treatment, says GlobalData, a leading data and analytics company. Madeleine Roche, MSc, Analyst at GlobalData comments: “Drug sales for Q4 2020 heavily influenced company performance, with COVID-19 vaccines driving market cap growth, but COVID-19 therapeutics possibly causing a decline. The top 10 companies (Johnson & Johnson, F. Hoffmann-La Roche, Novartis, Merck & Co, Pfizer, AbbVie, Eli […]
Diagnosed prevalent cases of HIV to reach 2.1 million by 2029 in the 7MM
The diagnosed prevalent cases of human immunodeficiency virus (HIV) in the seven major markets (7MM*) are projected to increase from 1.87 million in 2019 to 2.1 million in 2029, with an annual growth rate (AGR) of 1.06%, according to GlobalData, a leading data and analytics company. The company’s latest report, ‘Human Immunodeficiency Virus (HIV): Epidemiology […]
VELREAL study results may bolster current use of Velphoro among CKD-Hyperphosphatemia patients on dialysis
Velphoro’s (sucroferric oxyhydroxide) recent VELREAL multicenter study showed a 20% decrease in serum phosphorus in addition to reduced parathyroid hormone level in chronic kidney disease (CKD) patients on dialysis. This study could be of high clinical value to physicians with dialysis patients looking to find an optimal treatment of choice for hyperphosphatemia (HP) and hyperparathyroidism, […]
SARS-CoV-2 mutations could make COVID-19 endemic
The recent SARS-CoV-2 virus variant in South Africa (B.1.351) underscores a critical weakness in combatting the COVID-19 epidemic and may prolong it indefinitely, says GlobalData, a leading data and analytics company. South Africa made headlines when it announced that it would be suspending AstraZeneca’s COVID-19 vaccine (AZD1222). The vaccine’s efficacy was below 25% in South […]
Success in Parkinson’s disease development pipeline relies on Roche’s prasinezumab overcoming recent string of failures
The Parkinson’s disease (PD) pipeline has been hit significantly with a string of failures among its most anticipated mid-stage pipeline candidates. This news presents a challenge for similar disease-modifying therapies (DMTs) undergoing development such as Roche’s prasinezumab. It also amplifies that a major unmet need remains in bringing DMTs and neuroprotective agents to this market, […]
Sales of injectable anti-HIV therapeutics will reach US$2bn in 2029
The human immunodeficiency virus (HIV) therapeutics market was worth an estimated $22.9bn across the seven major markets (7MM*) in 2019. The market is expected to grow at a Compound Annual Growth Rate (CAGR) of 2%, reaching $28bn in 2029, according to GlobalData, a leading data and analytics company. GlobalData’s latest report, ‘HIV Therapeutics: Global Drug Forecast and Market Analysis to 2029’, reveals that growth in the market will be driven by […]
EOC Pharma well-positioned to bring innovative oncology drugs to China, says GlobalData
China-based EOC Pharma has recently entered an in-licensing partnership with US-based biopharmaceutical company Aadi Bioscience for the development and commercialization of ABI-009 (Fyarro). This deal, along with the previous in-licensing deals, clearly highlights EOC Pharma’s strategy to bring innovative oncology therapies for Chinese patients, says GlobalData, a leading data and analytics company. Under the agreement, […]
Gilead and Galapagos discontinuing IPF Phase III front-runner is a major setback in the disease space
Gilead and Galapagos recently announced the discontinuation of the ISABELA Phase III clinical trials investigating ziritaxestat, a once daily autotaxin inhibitor formerly known as GLPG-1690, in patients with idiopathic pulmonary fibrosis (IPF). Due to IPF’s high clinical unmet needs, this discontinuation represents a major setback in the disease space, according to GlobalData, a leading data […]
Takeda continues collaboration run to bolster global immuno-oncology footprint, says GlobalData
The need to develop novel innovative cancer drugs at affordable prices is forcing large pharmaceutical firms to collaborate with biotech companies and academic institutions. Japan-based Takeda Pharmaceuticals too is focusing on strategic collaborations to bolster its global immuno-oncology (IO) footprint, says GlobalData, a leading data and analytics company. In January 2021, Takeda entered a broad […]
High cost of therapy and toxicity issues are the most important unmet needs in immuno-oncology
As of 2020, unmet needs in immuno-oncology (IO) revolve around three main pillars: Cost, efficacy and toxicity. While a multitude of pipeline agents are poised to address needs related to toxicity and efficacy, with this level of industrial investment highlighting their importance for the future of IO, there is little incentive to optimize for issues […]
Caladrius Biosciences’ US sales of CLBS16 in CMD to reach $346m by 2028, despite market entry hurdles
Caladrius Biosciences’ initiation of the Phase IIb FREEDOM trial of its autologous CD34+ stem cell therapy, CLBS16, in coronary microvascular dysfunction (CMD), is an important development milestone. While concerns regarding the therapy’s scalability, potential cost and durability of the treatment effect will impact its market uptake, the drug is forecast to generate US sales of $364m by 2028, according to GlobalData, a leading data and analytics company. Kelly Lambrinos, Managing Analyst at GlobalData, comments: “There are no drugs that specifically […]
Brexit deal secures UK access to €95.5bn research and innovation program, says GlobalData
Through the Brexit deal struck between the UK and EU on 24 December 2021, the UK will be part of Horizon Europe, the EU’s next framework program for research and innovation. The UK-EU trade deal will give the UK researchers and businesses access to Horizon Europe funding on equivalent terms as EU counterparts, including eligibility to […]
Over 60% of UK Lupus Nephritis cases are diagnosed late, says GlobalData
Over 60% of diagnosed prevalent cases of lupus nephritis in the UK in are seen in class IV and V, says GlobalData, a leading data and analytics company. It is, therefore, likely that the diagnosis of lupus nephritis is often delayed. Nneoma Okeke, Epidemiologist at GlobalData, comments: “This could be due to an initial misdiagnosis […]
Verana Health will strengthen Janssen’s presence in ophthalmology in long-term, says GlobalData
Janssen Pharmaceuticals has recently partnered with Verana Health, which is specialized in data analytics in the field of ophthalmology and urology. The collaboration can help Janssen to derive clinical and business insights that can be critical for the development of drugs and understanding current treatment paradigms in ophthalmology in the long-term, says GlobalData, a leading […]
American Indians and Alaska natives should be prioritized for COVID-19 vaccines, says GlobalData
COVID-19 relief and vaccine roll-out should prioritize American Indians and Alaska Natives (AI/AN) populations, as they are a marginalized group in the US healthcare and are more likely to be hospitalized with severe symptoms than the general population. If vaccine rollout can indeed reach 75% of the AI/AN population, it is hopeful the pandemic in […]
Tidepool Loop app will be game-changing for type 1 diabetes management
If Tidepool’s diabetes management app Tidepool Loop gains its 510(k) clearance from the Food and Drug Administration (FDA), it will have a significant impact on patients’ ability to attain glycemic control, says GlobalData, a leading data and analytics company. This is especially prominent as only 20-30% of type 1 diabetes (T1D) patients meet their glycemic […]
Keytruda set to overthrow Adcetris monotherapy in the transplant ineligible setting in Hodgkin’s lymphoma following EU and FDA nod, says GlobalData
The FDA and EMA’s recent positive opinions on the expanded use of Merck & Co’s Keytruda (pembrolizumab) has the drug all set to catch up to Seagen’s Adcetris (brentuximab vedotin) in the transplant ineligible setting, according to GlobalData, a leading data and analytics company. The expansion is also likely to have a significant impact on […]
New COVID-19 strains are causing clinical trial resumptions to slow
Many clinical trials were set to resume activity as the initial peak of the COVID-19 virus started declining. However, with the number of confirmed COVID-19 cases rising globally, especially in Western areas such as the US and Europe, along with two more infectious variants of COVID-19, this has led to increased restrictive measures and has […]