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Bausch Health recently announced that it had entered into an agreement with Allegro to acquire an option to purchase all of the latter’s ophthalmology assets. This transaction will be a significant step for Bausch Health in its strategy to create a long-term growth opportunity, says GlobalData, a leading data and analytics company. Vinie Varkey, MSc, […]
Same day EC and Japanese MHLW wins for Gilead and Galapagos’ Jyseleca, but lost US revenues won’t be recovered
Gaining approval by the EC and Japanese Ministry of Health, Labour and Welfare (MHLW) on the same day for adults with moderate-to-severe active rheumatoid arthritis (RA) is a clear win for the developers of Jyseleca (filgotinib), however, this was at the heels of an FDA complete response letter (CRL). Given the importance of this market, […]
Pharma manufacturing across Southern India has strong M&A potential, says GlobalData
The pharma manufacturing in the three Southern Indian states of Karnataka, Tamil Nadu and Kerala, and Goa (Western India) has a high merger and acquisition (M&A) potential, given that 75% of pharma facilities in these states belong to companies with a single site in the region, says GlobalData, a leading data and analytics company. Adam […]
European dose manufacturing site purchases driven by solid dose’s low profitability
Three-fourths of dose manufacturing facilities acquired by dedicated CMOs in 2019 were located in Europe, according to an analysis of sites supplying the US, Canada, Europe, or Japan, says GlobalData, a leading data and analytics company. Adam Bradbury, Pharma Analyst at GlobalData, comments: “While European commercial dose facilities have been popular acquisitions for some time, […]
Oral GnRH antagonists could have market potential in female health space beyond endometriosis-related pain and uterine fibroid indications
Oral GnRH antagonists have off-label potential in the female infertility space, beyond the indications of endometriosis-associated pain and uterine fibroids, which constitute the main development focus for companies competing in the space, says GlobalData, a leading data and analytics company. Due to their novel oral formulation, the company notes that GnRH antagonists could replace subcutaneous […]
Competition intensifies in SMA market with new Evrysdi two-year data, says GlobalData
Following the news that Roche has announced new positive two-year data for Evrysdi (risdiplam) in infants with spinal muscular atrophy (SMA); Philippa Salter, Neurology Analyst at GlobalData, a leading data and analytics company, offers her view: “Having been approved earlier this year, Roche’s Evrysdi now reaches the market – albeit a whole four years behind […]
Competition intensifies in SMA market with new Evrysdi two-year data
Following the news that Roche has announced new positive two-year data for Evrysdi (risdiplam) in infants with spinal muscular atrophy (SMA); Philippa Salter, Neurology Analyst at GlobalData, a leading data and analytics company, offers her view: “Having been approved earlier this year, Roche’s Evrysdi now reaches the market – albeit a whole four years behind […]
PAH patients to benefit amid telemedicine regulatory changes
Following President Trump’s announced executive order directing the Department of Health and Human Services (HHS) to issue rules ensuring that specific regulatory changes to telemedicine will remain in place once the COVID-19 pandemic ends, HHS will need to healthcare access to rural areas and to create a novel value-based payment model to improve reimbursement, according […]
COVID-19 vaccine administered by nasal spray receives approval in China for Phase I study
Pharma companies around the world are exploring innovative approaches to develop therapeutics and vaccines against COVID-19. One of these innovations is using a nasal spray to deliver the vaccine and the intranasal spray vaccine being co-developed by Beijing Wantai Biological Pharmacy Enterprise with researchers from Xiamen University and Hong Kong University is the first of […]
Bispecific antibodies will start maturing after 2021 with estimated sales in oncology of $6bn by 2025
The clinical success of Amgen’s Blincyto has amplified the intensive pace of development for bispecific antibodies in oncology. According to GlobalData’s drugs database, there are 106 bispecific antibody molecules – with various targets – currently in the pipeline. Furthermore, there are 263 ongoing/planning to enroll clinical trials involving a bispecific antibody. Sakis Paliouras, PhD, Oncology […]
Global ALS market expected to grow to $1.04bn in 2029 driven by anticipated drug launches
The late-stage ALS pipeline has several promising therapies that look to address some of the unmet needs in the market. Pipeline strategies have focused on bringing first-in-class treatments to the market with the hope that they can at least extend patient survival, and, at best, have neuroprotective properties. This has led to a variety of different […]
Novartis’ intrathecal Zolgensma delay in older patients bodes well for competitors
Following a review of data from the Phase I STRONG study of the intrathecal (IT) formulation of Novartis’ one-off gene therapy Zolgensma (onasemnogene abeparvovec) in older patients with spinal muscular atrophy (SMA), the Food and Drug Adminstration (FDA) has requested a pivotal Phase III confirmatory study to further support the drug’s regulatory filing; Sarah Elsayed, […]
Crohn’s disease set to reach 1.6 million cases in 8MM by 2029
The diagnosed prevalent cases of Crohn’s disease (CD) in the eight major markets (*8MM) are projected to increase from 1,339,543 cases in 2019 to 1,629,940 cases in 2029, equating to an annual growth rate (AGR) of 2.17%, according to GlobalData, a leading data and analytics company. The natural course of CD, with low mortality, as well […]
vTV’s Alzheimer’s and type 2 diabetes therapy has some support for positive data but skepticism remains, says GlobalData
In light of another setback in the Alzheimer’s disease (AD) drug development field, with the failure of Roche and AC Immune’s antitau antibody, all eyes will be on results for vTv Therapeutics’ azeliragon for AD and type 2 diabetes; William Newton, Pharma Writer for the Investigative News team at GlobalData, offers his view: “Although azeliragon […]
Global opioid use disorder market to reach $3.7bn by 2028 driven by buprenorphine reformulations
The opioid use disorder (OUD) market is expected to grow from $1.6bn in 2018 to $3.7bn by 2028 across the eight major markets (8MM*) at a compound annual growth rate (CAGR) of 8.8%, according to GlobalData, a leading data and analytics company. The company’s latest report, ‘Opioid Use Disorder-Opportunity Analysis and Forecasts to 2028’, reveals […]
Amyotrophic lateral sclerosis set to increase to 65,900 cases in the 8MM in 2029 due to aging populations, says GlobalData
The diagnosed prevalent cases of amyotrophic lateral sclerosis (ALS) in the eight major markets (*8MM) is expected to increase from 57,800 cases in 2019 to 65,900 cases in 2029, at an annual growth rate (AGR) of 1.41%, according to GlobalData, a leading data and analytics company. The company’s latest report, ‘Amyotrophic Lateral Sclerosis: Epidemiology Forecast to […]
Pulmonary arterial hypertension set to increase to 68,200 cases in 7MM by 2029, says GlobalData
The diagnosed prevalent cases of pulmonary arterial hypertension (PAH) in the seven major markets (*7MM) is expected to increase from 67,400 cases in 2019 to 68,200 cases in 2029, at an annual growth rate (AGR) of 0.13%, according to GlobalData, a leading data and analytics company. The company’s latest report, ‘Pulmonary Arterial Hypertension: Epidemiology Forecast to […]
Positive CHMP opinion on Baricitinib in atopic dermatitis positions it to take on Dupixent, says GlobalData
Eli Lilly’s baricitinib, marketed as Olumiant in rheumatoid arthritis, has received a recommendation of approval from the European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) for moderate to severe adult atopic dermatitis (AD) patients, positioning the drug to take on Sanofi and Regeneron’s juggernaut Dupixent (dupilumab), says GlobalData, a leading data […]
Bars and nightclubs have increased risk of COVID-19 transmission, says GlobalData
Several COVID-19 outbreaks across the US since mid-June have been traced back to bars and nightclubs as the source of contagion. This coincides with a growing amount of evidence worldwide suggesting that indoor activities in areas with poor air circulation increases the risk for contracting COVID-19 – including preliminary results from a study in China […]
Trump’s executive order on drug pricing unlikely to have immediate impact on pharma industry, says GlobalData
One of the most worrying issues in regard to US healthcare is that the cost of treatment and therapeutics is unreasonably high – often to the point when care is unaffordable to many Americans. With the US often paying significantly more for drugs than other developed countries, how to achieve pricing parity is often the […]