Asthma Marketed and Pipeline Drugs Assessment, Clinical Trials and Competitive Landscape

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Asthma, a heterogeneous disease, causes variable respiratory symptoms such as wheezing, shortness of breath, chest tightness, and cough. There are millions of diagnosed prevalent cases of asthma worldwide. Although its etiology is not fully understood, certain host and environmental factors are associated with an increased risk of developing the disease.

The asthma marketed and pipeline drugs market research report includes an assessment of the disease epidemiology, leading marketed products with sales forecast, pricing and reimbursement, late-to-mid-stage pipeline products with phase transition success rate (PTSR), and likelihood of approval (LoA) for asthma. The report also analyzes the clinical and commercial landscapes of asthma as well as an assessment of deals, future market catalysts, key market players, and the future competitive environment.

Leading Marketed Drugs in Asthma

The current leading marketed drugs in asthma include IL-4R and IL-5R antagonists, an IgE inhibitor, a CHRM3 antagonist, and ADRB2/glucocorticoid receptor agonists. Dupilumab, Omalizumab, and Mepolizumab are some of the drugs on the market. Regeneron Pharmaceuticals – Dupixent, F. Hoffmann-La Roche – Xolair, and Boehringer Ingelheim – Spiriva Respimat are some of the key brands involved in the production of these drugs for asthma.

Asthma Marketed Drugs Segmentation by Mechanism of Action

The majority of marketed drugs for asthma are receptor agonists and receptor antagonists. Receptor agonist, receptor antagonist, enzyme inhibitor, biological factor inhibitor, and ion channel blocker are some of the primary mechanisms of action in the marketed drugs for asthma.

Asthma Marketed Drugs Analysis, by Mechanism of Action, 2022 (%)

Asthma Marketed Drugs Analysis, by Mechanism of Action

For more MoA insights into asthma marketed drugs, download a free report sample

Asthma Marketed Drugs Segmentation by Molecule Type

The majority of the marketed drugs for asthma are small molecules. Biologic and polymer are the other two significant molecule types in the marketed drugs for asthma.

Asthma Marketed Drugs Analysis, by Molecule Type, 2022 (%)

Asthma Marketed Drugs Analysis, by Molecule Type

For more molecule type insights into the asthma marketed drugs, download a free report sample

Asthma Marketed Drugs Segmentation by Routes of Administration

More than half of the marketed drugs for asthma utilize an oral route of administration. The other four RoA in the marketed drugs for asthma are injection, inhalational, topical, and suppository.

Asthma Marketed Drugs Analysis, by Routes of Administration, 2022 (%)

Asthma Marketed Drugs Analysis, by Routes of Administration

For more RoA insights into the asthma marketed drugs, download a free report sample

Leading Pipeline Drugs in Asthma

In the asthma pipeline, most of the drugs currently in Phase III stage of clinical development are targeting ADRB2 or IL-4 and 5. Tezepelumab, PT027 (Albuterol + budesonide), Trelegy Ellipta, and Benralizumab are some of the primary pipeline drugs in asthma.

Asthma Pipeline Drugs Segmentation by Mechanism of Action

Mechanisms of action for asthma pipeline drugs are varied, with a large number of receptor antagonists, biological factor inhibitors, enzyme inhibitors, receptor agonists, and protein/peptide inhibitors. However, receptor antagonist has the maximum asthma pipeline drugs.

Asthma Pipeline Drugs Analysis, by Mechanisms of Action, 2022 (%)

Asthma Pipeline Drugs Analysis, by Mechanisms of Action

For more MoA insights into the asthma pipeline drugs, download a free report sample

Asthma Pipeline Drugs Segmentation by Molecule Type

Currently majority of drugs in various development stages are biologics. Small molecule, and Oligonucleotide are the other two molecule types found in pipeline drugs in asthma.

Asthma Pipeline Drugs Analysis, by Molecule Types, 2022 (%)

Asthma Pipeline Drugs Analysis, by Molecule Types

For more molecule type insights into the asthma pipeline drugs, download a free report sample

Asthma Pipeline Drugs Segmentation by Routes of Administration

Of the pipeline drugs undergoing development for asthma with a known route of administration, injectable, inhalational, and oral therapies are all common, while only topical therapies are uncommon. Majority of the asthma pipeline drugs are injectable.

Asthma Pipeline Drugs Analysis, by Routes of Administration, 2022 (%)

Asthma Pipeline Drugs Analysis, by Routes of Administration

For more RoA insights into the asthma pipeline drugs, download a free report sample

Top Sponsors in the Asthma Marketed and Pipeline Drugs Market

AstraZeneca has sponsored the highest number of clinical trials of all the clinical trials in asthma that were initiated over the past 10 years. GSK plc., Novartis AG, and Teva Pharmaceutical Industries Ltd are some of the other top sponsors in the clinical trials of asthma marketed and pipeline drugs market.

Asthma Marketed Drugs Market Report Overview

Key Mechanisms of Action (Marketed Drugs) Receptor Agonist, Receptor Antagonist, Enzyme Inhibitor, Biological Factor Inhibitor, and Ion Channel Blocker
Analysis Year 2022
Key Routes of Administration (Marketed Drugs) Injections, Oral, Topical, Inhalational, And Suppository
Key Molecule Types (Marketed Drugs) Small Molecule, Biologic, and Polymer

 

Asthma Pipeline Drugs Market Report Overview

Key Mechanisms of Action (Pipeline Drugs) Receptor Antagonists, Biological Factor Inhibitors, Enzyme Inhibitors, Receptor Agonists, and Protein/Peptide Inhibitors
Analysis Year 2022
Key Routes of Administration (Pipeline Drugs) Injection, Inhalational, Topical, and Oral
Key Molecule Types (Pipeline Drugs) Small Molecule, Oligonucleotide, and Biologic
Top Sponsors AstraZeneca, Genentech, Uriach, Faes Farma, Menarini, Sanofi, Novartis, Teva, and Celltri GSK plc., Novartis AG, and Teva Pharmaceutical Industries Ltd

Asthma Marketed Drugs Market MoA Overview ( No of Drugs in the Pipeline, 2022)

  • Receptor Agonist
  • Receptor Antagonist
  • Enzyme Inhibitor
  • Biological Factor Inhibitor
  • Ion Channel Blocker

Asthma Marketed Drugs Market RoA Overview( No of Drugs in the Pipeline, 2022)

  • Injections
  • Oral
  • Topical
  • Inhalational
  • Suppository

Asthma Marketed Drugs Market Molecule Types Overview( No of Drugs in the Pipeline, 2022)

  • Small Molecule
  • Biologic
  • Polymer

Asthma Pipeline Drugs Market MoA Overview ( No of Drugs in the Pipeline, 2022)

  • Receptor Antagonists
  • Biological Factor Inhibitors
  • Enzyme Inhibitors
  • Receptor Agonists
  • Protein/Peptide Inhibitors

Asthma Pipeline Drugs Market RoA Overview ( No of Drugs in the Pipeline, 2022)

  • Injection
  • Inhalational
  • Topical
  • Oral

Asthma Pipeline Drugs Market Molecule Types Overview ( No of Drugs in the Pipeline, 2022)

  • Small Molecule
  • Oligonucleotide
  • Biologic

Scope

GlobalData’s “Asthma Marketed and Pipeline Drugs Assessment, Clinical Trials and Competitive Landscape” combines data from the Pharma Intelligence Center with in-house analyst expertise to provide a competitive assessment of the disease marketplace.

Components of the report include:

  • Disease Landscape
  • Disease Overview
  • Epidemiology Overview
  • Treatment Overview
  • Marketed Products Assessment
  • Breakdown by Mechanism of Action, Molecule Type, Route of Administration
  • Product Profiles with Sales Forecast
  • Pricing and Reimbursement Assessment
  • Retail or Manufacturer Price of Products
  • Time to Pricing and Time to Reimbursement
  • Pipeline Assessment
  • Breakdown by Development Stage, Mechanism of Action, Molecule Type, Route of Administration
  • Product Profiles with Sales Forecast
  • Late-to-mid-stage Pipeline Drugs
  • Phase Transition Success Rate and Likelihood of Approval
  • Clinical Trials Assessment
  • Breakdown of Trials by Phase, Status, Virtual Components, Sponsors, Geography, and Endpoint Status
  • Enrolment Analytics, Site Analytics, Feasibility Analysis
  • Deals Landscape
  • Mergers, Acquisitions, and Strategic Alliances by Region
  • Overview of Recent Deals
  • Commercial Assessment
  • Key Market Players
  • Future Market Catalysts

Reasons to Buy

  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the Asthma market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global Asthma market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and strategic partnerships.

Table of Contents

1 Preface

1.1 Contents

1.2 Report Scope

1.3 List of Tables and Figures

1.4 Abbreviations

2 Key Findings

3 Disease Landscape

3.1 Disease Overview

3.2 Epidemiology Overview

3.3 Treatment Overview

4 Marketed Drugs Assessment

4.1 Leading Marketed Drugs

4.2 Overview by Mechanism of Action

4.3 Overview by Route of Administration

4.4 Marketed Drugs Profiles and Sales Forecasts

5 Pricing and Reimbursement Assessment

5.1 Manufacturer Price

5.2 Time to Pricing and Reimbursement

6 Pipeline Drugs Assessment

6.1 Phase III Pipeline Drugs

6.2 Overview by Development Stage

6.3 Overview by Molecule Type

6.4 Overview by Mechanism of Action

6.5 Overview by Route of Administration

6.6 Drug Specific Phase Transition Success Rate (PTSR) and Likelihood of Approval (LoA)

6.7 Therapy Area and Indication-specific PTSR and LoA

7 Clinical Trials Assessment

7.1 Historical Overview

7.2 Overview by Phase

7.3 Overview by Status

7.4 Overview by Phase for Ongoing and Planned Trials

7.5 Trials with Virtual Components

7.6 Geographic Overview

7.7 Single-Country and Multinational Trials by Region

7.8 Top 20 Sponsors with Breakdown by Phase

7.9 Top 20 Sponsors with Breakdown by Status

7.10 Overview by Endpoint Status

7.11 Overview by Race and Ethnicity

7.12 Enrollment Data

7.13 Top 20 countries for Trial Sites

7.14 Top 20 Sites Globally

7.15 Feasibility Analysis – Geographic Overview

7.16 Feasibility Analysis – Benchmark Models

8 Deals Landscape

8.1 Mergers, Acquisitions, and Strategic Alliances by Region

8.2 Recent Mergers, Acquisitions, and Strategic Alliances

9 Commercial Assessment

9.1 Key Market Players

10 Future Market Catalysts

11 Appendix

11.1 Methodology

11.2 Methodology – Sales Forecast

11.3 Methodology – Pricing and Reimbursement

11.4 Methodology – PTSR and LoA Analysis

11.5 About the Authors

11.6 Contact Us

11.7 Disclaimer

Frequently asked questions

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