Likelihood of Approval and Phase Transition Success Rate Model – Avelumab in Metastatic Colorectal Cancer
Powered by
Unlock hidden opportunities in the LoA industry
Empower your strategies with our Likelihood of Approval and Phase Transition Success Rate Model – Avelumab in Metastatic Colorectal Cancer report and make more profitable business decisions.
This report provides you with the data that allows you to track and predict the specific likelihood of approval (LOA) and phase transition success rate (PTSR) of a drug using GlobalData’s proprietary machine learning algorithms developed using over 10 years of historical data.
Avelumab in Metastatic Colorectal Cancer Drug Details:
Avelumab (MSB-0010718C, Bavencio) is a programmed human IgG1 lambda monoclonal antibody. It is formulated as solution and concentrate solution for intravenous route of administration. Avelumab is indicated for the treatment of adults and pediatric patients 12 years and older with metastatic Merkel cell carcinoma. It is also indicated for the treatment of patients with locally advanced or metastatic urothelial carcinoma (UC) who have disease progression during or following platinum-containing chemotherapy, or who have disease progression within 12 months of neoadjuvant or adjuvant treatment with platinum-containing chemotherapy, in combination with axitinib is indicated for the first-line treatment of patients with advanced renal cell carcinoma (RCC), and for maintenance treatment of patients with locally advanced or metastatic urothelial carcinoma (UC) that has not progressed with first-line platinum-containing chemotherapy.Avelumab (MSB-0010718C) is under development for the treatment of advanced or metastatic squamous anal cancer (SCCAC), metastatic non-squamous non-small cell lung cancer, adenocarcinoma of the gastro esophageal junction, gastric cancer, homologous-recombination deficient (HRD) ovarian cancer, diffuse large b-cell lymphoma, non-small cell lung cancer, bladder cancer, metastatic transitional cell carcinoma of the urothelium including the bladder, urethra, renal pelvis, and ureter, epithelial ovarian cancer, fallopian tube cancer, peritoneal cancer, head and neck cancer squamous cell carcinoma, epithelial ovarian cancer, fallopian tube cancer, peritoneal cancer, TNBC, squamous non-small cell lung cancer, colorectal cancer, neuroendocrine carcinoma, renal pelvis cancer, upper urinary tract cancer and bladder cancer, urethral cancer, follicular lymphoma, hepatocellular carcinoma, metastatic hormone refractory (castration resistant, androgen-independent) prostate cancer, muscle invasive bladder cancer (MIBC), recurrent head and neck cancer squamous cell carcinoma, endometrial cancer, peripheral t-cell lymphomas (PTCL),anaplastic large cell lymphoma (ALCL),natural killer cell lymphomas, transformed mycosis fungoides, angioimmunoblastic t-cell lymphoma (AITL)/immunoblastic lymphadenopathy, angiosarcoma, glioblastoma (GBM),small-cell lung cancer, osteosarcoma, relapsed acute myeloid leukemia, refractory acute myeloid leukemia, malignant mesothelioma, hepatobiliary system tumor, adrenocortical carcinoma (adrenal cortex cancer), head and neck cancer squamous cell carcinoma, pancreatic cancer, mantle cell lymphoma, meningioma, squamous cell carcinoma, penile cancer and precancerous condition. It was also under development for the treatment of neuroendocrine gastroenteropancreatic tumors (GEP-NET), neuroendocrine tumors, renal cell carcinoma, Hodgkin lymphoma (B-Cell Hodgkin lymphoma), gastric cancer, adenocarcinoma of the gastroesophageal junction (third-line therapy), epithelial ovarian cancer (first line therapy, second-line therapy),fallopian tube cancer, peritoneal cancer, non-small cell lung cancer (second line therapy), cervical cancer, Merkel cell carcinomax, nasopharyngeal cancer, leiomyosarcoma, pancreatic ductal adenocarcinoma, relapsed /refractory multiple myeloma, colon cancer, central nervous system tumor, progressing tenosynovial giant cell tumor/pigmented villonodular synovitis, melanoma, glioma and head and neck cancer
Report Coverage
The data is segmented by drug name per indication and shows the current likelihood of approval for the drug compared to the indication benchmark and the industry benchmark.
The Likelihood of Approval data is updated regularly based on events that take place which impact the clinical development process and regulatory considerations. GlobalData’s proprietary machine learning models consider these events in real time, to produce quantitative changes to the LOA and PTSR along with qualitative reasoning why the likelihood of approval has changed.
Quick View – Avelumab LOA Data | |||||
Report Segments |
|
||||
Drug Name |
|
||||
Administration Pathway |
|
||||
Therapeutic Areas |
|
||||
Key Manufacturers |
|
||||
Drug Development Status |
|
Reasons to Buy
- Precise Likelihood of Approval and Phase Transition Success Rates: Our machine learning and proprietary models provide accurate predictions, helping you gauge the potential success of a drug in the regulatory process.
- Competitive Strategy Planning: Access information on LOA and PTSR for competitors’ drugs, allowing you to plan your clinical development, commercialisation and marketing strategies
- Event-driven Updates: Track event-driven changes in LOA and PTSR benchmarked against indication LOA/PTSR. Get the latest insights to adapt your strategies promptly!
- Well-informed Investment Decisions: This data helps you navigate the dynamic landscape of drug development and regulatory considerations.
Scope
- Drug Details: Drug name, Drug type, Intervention type
- Administration Pathway
- Therapeutic Areas
- Key Manufacturers
- Drug Development Status
This is an on-demand report that will be delivered upon request. The report will be delivered within 2 business days of the purchase, excluding weekends and holidays. Certain sections of the report may be removed or altered based on data availability and relevance.
Frequently asked questions
- Drugs which have been approved in the past 10 years
- Drugs which have failed during clinical development in the past 18 years
- Drugs which are currently in development
- Phase I, Phase II, Phase III, and Pre-Registration development stage
- Drugs must meet one of the following criteria to be included in the model:
- The developer has specified the US as an intended market for approval.
- The developer has not specified any country as an intended market for approval, i.e. the “Drug Geography” is listed as “Global”
- Innovator drugs and biosimilars
- Diagnostics, Imaging Agents, Biomarkers, stents and other drug delivery devices (covered in GlobalData’s Medical Intelligence Center).
- Nutraceuticals, dietary supplements, alternative medicines, imaging agents, radio emitter, transplants, transfusions, fillers, cosmetics, probiotics, antiseptics, antacids, mobilizing agents, veterinary drugs and drugs not seeking approval.
- Generic drugs
- Innovative drugs in Preclinical or Discovery Stage.
- Pipeline drugs sponsored by a Government or Institution.
- Drugs with a specific Drug Geography not the United States.
The probability of a drug ultimately receiving market authorization
The probability of a drug’s advancement to the next stage of clinical development
GlobalData’s Drug-Specific Likelihood of Approval (LoA) calculates the Phase Transition Success Rate (PTSR) and Likelihood of Approval (LoA) customized to individual drug. The model uses a combination of Machine Learning (ML) and a GlobalData proprietary algorithm to process data points from the Drugs, Clinical Trials, Regulatory Milestones, Company, and Financial databases.
Inclusion
Data Scope:
Drug Phase Scope:
Drug Geography Scope:
Drug Type Scope:
Entity Type Scope:
Only drugs in development by companies are included in the model.
Exclusion
Get in touch to find out about multi-purchase discounts
reportstore@globaldata.com
Tel +44 20 7947 2745