Heterozygous familial hypercholesterolemia (heFH) Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

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The Heterozygous familial hypercholesterolemia (heFH) pipeline drugs market research report provides comprehensive information on the therapeutics under development for Heterozygous familial hypercholesterolemia (heFH) (Metabolic Disorders), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history, and the latest news and press releases. Additionally, the report reviews key players involved in therapeutic development for heFH and features dormant and discontinued projects.

heFH Pipeline Drugs Market Segmentation by Targets

Some of the key targets of the heFH pipeline drugs market are Proprotein Convertase Subtilisin/Kexin Type 9, 3 Hydroxy 3 Methylglutaryl Coenzyme A Reductase, Angiopoietin Related Protein 3, ATP Citrate Synthase (ATP Citrate, Cholesteryl Ester Transfer Protein, and Type 1 Angiotensin II Receptor.

heFH Pipeline Drugs Market Analysis, by Targets

heFH Pipeline Drugs Market Analysis, by Targets

For more heFH pipeline drugs market target insights, download a free report sample

heFH Pipeline Drugs Market Segmentation by Mechanisms of Action

Some of the key mechanisms of action of the heFH pipeline drugs market are Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor, 3 Hydroxy 3 Methylglutaryl Coenzyme A Reductase Inhibitor, Angiopoietin Related Protein 3 Inhibitor, ATP Citrate Synthase (ATP Citrate Inhibitor, Cholesteryl Ester Transfer Protein Inhibitor, and Type 1 Angiotensin II Receptor Antagonist.

heFH Pipeline Drugs Market Analysis, by Mechanisms of Action

heFH Pipeline Drugs Market Analysis, by Mechanisms of Action

For more mechanism of action insights into the heFH pipeline drugs market, download a free report sample

heFH Pipeline Drugs Market Segmentation by Routes of Administration

The key routes of administration in the heFH pipeline drugs market are subcutaneous, intravenous, and oral.

heFH Pipeline Drugs Market Analysis, by Routes of Administration

heFH Pipeline Drugs Market Analysis, by Routes of Administration

For more routes of administration insights into the heFH pipeline drugs market, download a free report sample

heFH Pipeline Drugs Market Segmentation by Molecule Types

The key molecule types in the heFH pipeline drugs market are monoclonal antibody, gene therapy, small molecule, antisense RNAi oligonucleotide, and fusion protein.

heFH Pipeline Drugs Market Analysis, by Molecule Types

heFH Pipeline Drugs Market Analysis, by Molecule Types

For more molecule type insights into the heFH pipeline drugs market, download a free report sample

heFH Pipeline Drugs Market - Competitive Landscape

Some of the leading companies in the heFH pipeline drugs market are Verve Therapeutics Inc, Regeneron Pharmaceuticals Inc, Akeso Inc, Amgen Inc, Beijing Mabworks Biotech Co Ltd, Daewoong Pharmaceutical Co Ltd, Epicrispr Biotechnologies Inc, Esperion Therapeutics Inc, Innovent Biologics Inc, and LIB Therapeutics LLC.

heFH Pipeline Drugs Market Analysis, by Companies

heFH Pipeline Drugs Market Analysis, by Companies

To know more about the companies in the heFH pipeline drugs market, download a free report sample

heFH Pipeline Drugs Market Report Overview

Key Targets Proprotein Convertase Subtilisin/Kexin Type 9, 3 Hydroxy 3 Methylglutaryl Coenzyme A Reductase, Angiopoietin Related Protein 3, ATP Citrate Synthase (ATP Citrate, Cholesteryl Ester Transfer Protein, and Type 1 Angiotensin II Receptor
Key Mechanisms of Action Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor, 3 Hydroxy 3 Methylglutaryl Coenzyme A Reductase Inhibitor, Angiopoietin Related Protein 3 Inhibitor, ATP Citrate Synthase (ATP Citrate Inhibitor, Cholesteryl Ester Transfer Protein Inhibitor, and Type 1 Angiotensin II Receptor Antagonist
Key Routes of Administration Subcutaneous, Intravenous, and Oral
Key Molecule Types Monoclonal Antibody, Gene Therapy, Small Molecule, Antisense RNAi Oligonucleotide, and Fusion Protein
Leading Companies Verve Therapeutics Inc, Regeneron Pharmaceuticals Inc, Akeso Inc, Amgen Inc, Beijing Mabworks Biotech Co Ltd, Daewoong Pharmaceutical Co Ltd, Epicrispr Biotechnologies Inc, Esperion Therapeutics Inc, Innovent Biologics Inc, and LIB Therapeutics LLC

Scope

This report provides:

  • A snapshot of the global therapeutic landscape of Heterozygous familial hypercholesterolemia (heFH) (Metabolic Disorders).
  • Reviews of pipeline therapeutics for Heterozygous familial hypercholesterolemia (heFH) (Metabolic Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • Pipeline products based on several stages of development ranging from pre-registration to discovery and undisclosed stages.
  • Descriptive drug profiles for the pipeline products which comprise product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • Reviews of key companies involved in Heterozygous familial hypercholesterolemia (heFH) (Metabolic Disorders) therapeutics and enlists all their major and minor projects.
  • Evaluation of Heterozygous familial hypercholesterolemia (heFH) (Metabolic Disorders) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA), and molecule type.
  • All the dormant and discontinued pipeline projects.
  • Reviews of the latest news related to pipeline therapeutics for Heterozygous familial hypercholesterolemia (heFH) (Metabolic Disorders).

Reasons to Buy

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counterstrategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Heterozygous familial hypercholesterolemia (heFH) (Metabolic Disorders).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and their most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Heterozygous familial hypercholesterolemia (heFH) (Metabolic Disorders) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from the pipeline.

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Heterozygous familial hypercholesterolemia (heFH) – Overview

Heterozygous familial hypercholesterolemia (heFH) – Therapeutics Development

Pipeline Overview

Pipeline by Companies

Products under Development by Companies

Heterozygous familial hypercholesterolemia (heFH) – Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Heterozygous familial hypercholesterolemia (heFH) – Companies Involved in Therapeutics Development

Akeso Inc

Amgen Inc

Beijing Mabworks Biotech Co Ltd

Daewoong Pharmaceutical Co Ltd

Epicrispr Biotechnologies Inc

Esperion Therapeutics Inc

Innovent Biologics Inc

LIB Therapeutics LLC

NeuroBo Pharmaceuticals Inc

NewAmsterdam Pharma BV

Novartis AG

Regeneron Pharmaceuticals Inc

Shanghai Junshi Bioscience Co Ltd

Verve Therapeutics Inc

Heterozygous familial hypercholesterolemia (heFH) – Drug Profiles

alirocumab – Drug Profile

Product Description

Mechanism Of Action

bempedoic acid – Drug Profile

Product Description

Mechanism Of Action

ebronucimab – Drug Profile

Product Description

Mechanism Of Action

EPIC-221 – Drug Profile

Product Description

Mechanism Of Action

evinacumab – Drug Profile

Product Description

Mechanism Of Action

evolocumab – Drug Profile

Product Description

Mechanism Of Action

gemcabene – Drug Profile

Product Description

Mechanism Of Action

inclisiran – Drug Profile

Product Description

Mechanism Of Action

lerodalcibep – Drug Profile

Product Description

Mechanism Of Action

MIL-86 – Drug Profile

Product Description

Mechanism Of Action

obicetrapib – Drug Profile

Product Description

Mechanism Of Action

ongericimab – Drug Profile

Product Description

Mechanism Of Action

ST-103 – Drug Profile

Product Description

Mechanism Of Action

tafolecimab – Drug Profile

Product Description

Mechanism Of Action

VERVE-101 – Drug Profile

Product Description

Mechanism Of Action

Heterozygous familial hypercholesterolemia (heFH) – Dormant Projects

Heterozygous familial hypercholesterolemia (heFH) – Discontinued Products

Heterozygous familial hypercholesterolemia (heFH) – Product Development Milestones

Featured News & Press Releases

Sep 21, 2022: Verve Therapeutics announces clearance of clinical trial authorisation application by the United Kingdom Medicines and Healthcare Products Regulatory Agency for VERVE-101 in patients with heterozygous familial hypercholesterolemia

Aug 29, 2022: New Amgen data at ESC 2022 show long-term LDL-C lowering with REPATHA (evolocumab) was well-tolerated for more than 8 years

Aug 29, 2022: NewAmsterdam Pharma showcases leadership in cardiometabolic disease treatment in multiple presentations at ESC congress 2022

Aug 29, 2022: AMGEN to present new data at ESC Congress 2022 highlighting up To

8.5 years of Repatha (Evolocumab) safety and tolerability data in high-risk ASCVD patient populations

Jul 28, 2022: NewAmsterdam pharma doses first patient in phase 3 BROOKLYN clinical trial evaluating obicetrapib in patients with heterozygous familial hypercholesterolemia

Jul 12, 2022: Verve Therapeutics doses first human with an investigational in vivo base editing medicine, VERVE-101, as a potential treatment for heterozygous familial hypercholesterolemia

May 09, 2022: Verve Therapeutics reports additional VERVE-101 and GalNAc-Lipid Nanoparticle Delivery data in non-human primates at TIDES USA 2022

May 02, 2022: Esperion announces publication of CLEAR Harmony open-label extension study data for Bempedoic Acid in the American Journal of Cardiology

Apr 27, 2022: Amgen announces results from two open label extension studies of Repatha (evolocumab)

Apr 03, 2022: Innovent releases results of a phase 3 clinical study of IBI306 (PCSK-9 inhibitor) in Chinese patients with heterozygous familial hypercholesterolemia at the American College of Cardiology Annual Congress 2022

Feb 08, 2022: Leqvio therapy to lower cholesterol approved by FDA, IVX Health now accepting new Leqvio patients

Oct 15, 2021: Amgen’s evolocumab receives positive CHMP opinion for the treatment of Heterozygous familial hypercholesterolemia and Familial Hypercholesterolemia

Sep 24, 2021: FDA approves Repatha (evolocumab) in pediatric patients age 10 and older with heterozygous familial hypercholesterolemia

Aug 12, 2021: Innovent’s antibody therapy meets primary goal in Phase III HeFH trial

May 19, 2021: Verve Therapeutics announces Nature publication highlighting its use of base editing to potently and durably lower blood PCSK9 and LDL-C in non-human primates

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Products under Development for Heterozygous familial hypercholesterolemia (heFH), 2022

Number of Products under Development by Companies, 2022

Products under Development by Companies, 2022

Number of Products by Stage and Target, 2022

Number of Products by Stage and Mechanism of Action, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by Akeso Inc, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by Amgen Inc, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by Beijing Mabworks Biotech Co Ltd, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by Daewoong Pharmaceutical Co Ltd, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by Epicrispr Biotechnologies Inc, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by Esperion Therapeutics Inc, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by Innovent Biologics Inc, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by LIB Therapeutics LLC, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by NeuroBo Pharmaceuticals Inc, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by NewAmsterdam Pharma BV, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by Novartis AG, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by Regeneron Pharmaceuticals Inc, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by Shanghai Junshi Bioscience Co Ltd, 2022

Heterozygous familial hypercholesterolemia (heFH) – Pipeline by Verve Therapeutics Inc, 2022

Heterozygous familial hypercholesterolemia (heFH) – Dormant Projects, 2022

Heterozygous familial hypercholesterolemia (heFH) – Discontinued Products, 2022

Figures

List of Figures

Number of Products under Development for Heterozygous familial hypercholesterolemia (heFH), 2022

Number of Products under Development by Companies, 2022

Number of Products by Top 10 Targets, 2022

Number of Products by Stage and Top 10 Targets, 2022

Number of Products by Top 10 Mechanism of Actions, 2022

Number of Products by Stage and Top 10 Mechanism of Actions, 2022

Number of Products by Top 10 Routes of Administration, 2022

Number of Products by Stage and Top 10 Routes of Administration, 2022

Number of Products by Top 10 Molecule Types, 2022

Number of Products by Stage and Top 10 Molecule Types, 2022

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