Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC 3.5.1.98) Drugs in Development by Therapy Areas and Indications, Stages, MoA, RoA, Molecule Type and Key Players, 2022 Update

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Histone Deacetylase 6 (HDAC6) gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. It also plays a central role in microtubule-dependent cell motility via the deacetylation of tubulin.

The HDAC6 pipeline market research report provides comprehensive information on the HDAC6 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research, and development history as well as the latest news and press releases. Additionally, the report provides an overview of key players involved in Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC 3.5.1.98) targeted therapeutics development with respective active and dormant or discontinued projects.

Key Therapy Areas in the HDAC6 Pipeline Products Market

The key therapy areas in the HDAC6 pipeline products market are oncology, central nervous system, genetic disorders, immunology, toxicology, respiratory, cardiovascular, gastrointestinal, infectious disease, and musculoskeletal disorders. Oncology has the highest number of pipeline products in the HDAC6 pipeline products market.

HDAC6 Pipeline Products Market Analysis by Therapy Areas

HDAC6 Pipeline Products Market Analysis by Therapy Areas

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Key Mechanisms of Action in the HDAC6 Pipeline Products Market

The key mechanism of action in the HDAC6 pipeline products market is Histone Deacetylase 6 Inhibitor.

Key Routes of Administration in the HDAC6 Pipeline Products Market

The key routes of administration in the HDAC6 pipeline products market are oral, parenteral, and topical.

HDAC6 Pipeline Products Market Analysis by Routes of Administration

HDAC6 Pipeline Products Market Analysis by Routes of Administration

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Key Molecule Types in the HDAC6 Pipeline Products Market

The key molecule types in the HDAC6 pipeline products market are small molecule and synthetic peptide.

HDAC6 Pipeline Products Market Analysis by Molecule Types

HDAC6 Pipeline Products Market Analysis by Molecule Types

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Major Companies in the HDAC6 Pipeline Products Market

Some of the major companies in the HDAC6 pipeline products market are Annji Pharmaceutical Co Ltd, ATP Biopharm, Augustine Therapeutics, Avstera Therapeutics Inc, Beijing Konruns Pharmaceutical Co Ltd, Bristol-Myers Squibb Co, Chong Kun Dang Pharmaceutical Corporation, Convalife, CStone Pharmaceuticals Co Ltd, and Curis Inc.

HDAC6 Pipeline Products Market Analysis by Companies

HDAC6 Pipeline Products Market Analysis by Companies

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HDAC6 Pipeline Products Market Report Overview

Key Therapy Areas Oncology, Central Nervous System, Genetic Disorders, Immunology, Toxicology, Respiratory, Cardiovascular, Gastrointestinal, Infectious Disease, and Musculoskeletal Disorders
Key Mechanisms of Action Histone Deacetylase 6 Inhibitor
Key Routes of Administration Oral, Parenteral, and Topical
Key Molecule Type Small Molecule and Synthetic Peptide
Major Companies Annji Pharmaceutical Co Ltd, ATP Biopharm, Augustine Therapeutics, Avstera Therapeutics Inc, Beijing Konruns Pharmaceutical Co Ltd, Bristol-Myers Squibb Co, Chong Kun Dang Pharmaceutical Corporation, Convalife, CStone Pharmaceuticals Co Ltd, and Curis Inc

Scope

  • The report provides a snapshot of the global therapeutic landscape for Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC 3.5.1.98)
  • The report reviews Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC 3.5.1.98) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
  • The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
  • The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
  • The report reviews key players involved in Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC 3.5.1.98) targeted therapeutics and enlists all their major and minor projects
  • The report assesses Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC 3.5.1.98) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
  • The report summarizes all the dormant and discontinued pipeline projects
  • The report reviews the latest news and deals related to Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC 3.5.1.98) targeted therapeutics

Reasons to Buy

  • Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage
  • Identify and understand the targeted therapy areas and indications for Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC 3.5.1.98)
  • Identify the use of drugs for target identification and drug repurposing
  • Identify potential new clients or partners in the target demographic
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Plan mergers and acquisitions effectively by identifying key players and their most promising pipeline therapeutics
  • Devise corrective measures for pipeline projects by understanding Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC 3.5.1.98) development landscape
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Annji Pharmaceutical Co Ltd
ATP Biopharm
Augustine Therapeutics
Avstera Therapeutics Inc
Beijing Konruns Pharmaceutical Co Ltd
Bristol-Myers Squibb Co
Chong Kun Dang Pharmaceutical Corporation
Convalife
CStone Pharmaceuticals Co Ltd
Curis Inc
Eikonizo Therapeutics Inc
Guangdong Zhongsheng Pharmaceutical Co Ltd
Hillstream BioPharma Inc
Jubilant Therapeutics Inc
Kancera AB
Karus Therapeutics Ltd
KYAN Therapeutics Inc
Medivir AB
Merck & Co Inc
Mycovia Pharmaceuticals Inc
OnKure Inc
Oryzon Genomics SA
Quimatryx SL
Shuttle Pharmaceuticals Inc
SK Biopharmaceuticals Co Ltd
Starwise Therapeutics LLC
Suzhou GenHouse Pharmaceutical Co Ltd
Tenaya Therapeutics Inc

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC

3.5.1.98) – Overview

Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC

3.5.1.98) – Therapeutics Development

Products under Development by Stage of Development

Products under Development by Therapy Area

Products under Development by Indication

Products under Development by Companies

Products under Development by Universities/Institutes

Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC

3.5.1.98) – Therapeutics Assessment

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC

3.5.1.98) – Companies Involved in Therapeutics Development

Annji Pharmaceutical Co Ltd

ATP Biopharm

Augustine Therapeutics

Avstera Therapeutics Inc

Beijing Konruns Pharmaceutical Co Ltd

Bristol-Myers Squibb Co

Chong Kun Dang Pharmaceutical Corporation

Convalife

CStone Pharmaceuticals Co Ltd

Curis Inc

Eikonizo Therapeutics Inc

Guangdong Zhongsheng Pharmaceutical Co Ltd

Hillstream BioPharma Inc

Jubilant Therapeutics Inc

Kancera AB

Karus Therapeutics Ltd

KYAN Therapeutics Inc

Medivir AB

Merck & Co Inc

Mycovia Pharmaceuticals Inc

OnKure Inc

Oryzon Genomics SA

Quimatryx SL

Shuttle Pharmaceuticals Inc

SK Biopharmaceuticals Co Ltd

Starwise Therapeutics LLC

Suzhou GenHouse Pharmaceutical Co Ltd

Tenaya Therapeutics Inc

Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC

3.5.1.98) – Drug Profiles

ACY-1083 – Drug Profile

Product Description

Mechanism Of Action

History of Events

ACY-738 – Drug Profile

Product Description

Mechanism Of Action

History of Events

ACY-775 – Drug Profile

Product Description

Mechanism Of Action

History of Events

ADV-300 – Drug Profile

Product Description

Mechanism Of Action

AJ-302 – Drug Profile

Product Description

Mechanism Of Action

History of Events

AJ-303 – Drug Profile

Product Description

Mechanism Of Action

History of Events

AVS-100 – Drug Profile

Product Description

Mechanism Of Action

History of Events

C-1A – Drug Profile

Product Description

Mechanism Of Action

citarinostat – Drug Profile

Product Description

Mechanism Of Action

History of Events

CKD-504 – Drug Profile

Product Description

Mechanism Of Action

History of Events

CKD-506 – Drug Profile

Product Description

Mechanism Of Action

History of Events

CKD-510 – Drug Profile

Product Description

Mechanism Of Action

History of Events

CKD-L – Drug Profile

Product Description

Mechanism Of Action

CS-3003 – Drug Profile

Product Description

Mechanism Of Action

History of Events

CVL-608 – Drug Profile

Product Description

Mechanism Of Action

History of Events

CX-1026 – Drug Profile

Product Description

Mechanism Of Action

History of Events

EKZ-001 – Drug Profile

Product Description

Mechanism Of Action

History of Events

fimepinostat – Drug Profile

Product Description

Mechanism Of Action

History of Events

GH-36 – Drug Profile

Product Description

Mechanism Of Action

HDAC6 – Drug Profile

Product Description

Mechanism Of Action

HSB-510 – Drug Profile

Product Description

Mechanism Of Action

History of Events

JBI-097 – Drug Profile

Product Description

Mechanism Of Action

History of Events

JBI-802 – Drug Profile

Product Description

Mechanism Of Action

History of Events

KA-2507 – Drug Profile

Product Description

Mechanism Of Action

History of Events

KAN-0440262 – Drug Profile

Product Description

Mechanism Of Action

History of Events

KYAN-001 – Drug Profile

Product Description

Mechanism Of Action

History of Events

MPT-0B291 – Drug Profile

Product Description

Mechanism Of Action

MPT-0G211 – Drug Profile

Product Description

Mechanism Of Action

History of Events

Nexturastat A – Drug Profile

Product Description

Mechanism Of Action

QTX-125 – Drug Profile

Product Description

Mechanism Of Action

History of Events

QTX-153 – Drug Profile

Product Description

Mechanism Of Action

History of Events

remetinostat – Drug Profile

Product Description

Mechanism Of Action

History of Events

ricolinostat – Drug Profile

Product Description

Mechanism Of Action

History of Events

RTSV-5 – Drug Profile

Product Description

Mechanism Of Action

History of Events

SE-7552 – Drug Profile

Product Description

Mechanism Of Action

History of Events

SKLB-23bb – Drug Profile

Product Description

Mechanism Of Action

History of Events

Small Molecule to Inhibit HDAC1 and HDAC6 for Breast Cancer – Drug Profile

Product Description

Mechanism Of Action

History of Events

Small Molecule to Inhibit HDAC1, HDAC3 and HDAC6 for Lung Adenocarcinoma – Drug Profile

Product Description

Mechanism Of Action

Small Molecule to Inhibit HDAC6 for Charcot-Marie-Tooth Disease Type II A – Drug Profile

Product Description

Mechanism Of Action

Small Molecule to Inhibit HDAC6 for Melanoma – Drug Profile

Product Description

Mechanism Of Action

Small Molecule to Inhibit HDAC6 for Sepsis – Drug Profile

Product Description

Mechanism Of Action

Small Molecules for Charcot-Marie-Tooth Disease – Drug Profile

Product Description

Mechanism Of Action

Small Molecules to Inhibit HDAC-6 for Autoimmune Disorders, Charcot-Marie-Tooth Disease and Pancreatic Cancer – Drug Profile

Product Description

Mechanism Of Action

Small Molecules to Inhibit HDAC6 for Alzheimer’s Disease – Drug Profile

Product Description

Mechanism Of Action

History of Events

Small Molecules to Inhibit HDAC6 for Glioblastoma – Drug Profile

Product Description

Mechanism Of Action

Small Molecules to Inhibit HDAC6 for Immunology and Oncology – Drug Profile

Product Description

Mechanism Of Action

Small Molecules to Inhibit HDAC6 for Oncology – Drug Profile

Product Description

Mechanism Of Action

Small Molecules to Inhibit HDAC6 for Rett Syndrome – Drug Profile

Product Description

Mechanism Of Action

History of Events

Small Molecules to Inhibit HDAC6 for Unspecified Indications – Drug Profile

Product Description

Mechanism Of Action

History of Events

SP-259 – Drug Profile

Product Description

Mechanism Of Action

Synthetic Peptides to Inhibit HDAC6 for Solid tumor, Fibrosis and Neurology – Drug Profile

Product Description

Mechanism Of Action

TN-301 – Drug Profile

Product Description

Mechanism Of Action

History of Events

vorinostat – Drug Profile

Product Description

Mechanism Of Action

History of Events

Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC

3.5.1.98) – Dormant Products

Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC

3.5.1.98) – Product Development Milestones

Featured News & Press Releases

Jul 06, 2022: Tenaya Therapeutics publishes preclinical data in science translational medicine detailing discovery of HDAC6 inhibitor for treatment of heart failure

May 20, 2022: Tenaya Therapeutics to present preclinical data on TN-301 HDAC6 inhibitor at European Society of Cardiology Heart Failure 2022 Conference

Apr 26, 2022: Jubilant Therapeutics doses first patient in phase I/II trial evaluating JBI-802, dual inhibitor of LSD1 and HDAC6, in patients with advanced solid tumors

Mar 11, 2022: AnnJi Pharmaceutical’s HDAC6 selective inhibitor received “Grass Roots” support program award sponsored by Boehringer Ingelheim, Taiwan

Feb 01, 2022: Hillstream BioPharma announces acceptance of abstract at AACR 2022 annual meeting highlighting HSB-510, a novel quatramer-based, first-in-class dual inhibitor of HDAC6 and PI3K-delta downregulating c-myc expression

Jan 06, 2022: Jubilant Therapeutics announces FDA clearance of IND for JBI-802, a novel dual LSD1 and HDAC6 inhibitor, for treatment of solid tumors

Nov 18, 2021: Results from investigator-initiated phase II clinical study of remetinostat in patients with squamous cell carcinoma published

Sep 30, 2021: Jubilant Therapeutics announces successful completion of Pre-IND meeting with FDA for its novel dual LSD1 and HDAC6 inhibitor JB1-802

Aug 16, 2021: Medivir strengthens the business development potential of remetinostat through renegotiated multi-party agreement

Aug 12, 2021: Positive data from the remetinostat phase II study in basal cell carcinoma published in Clinical Cancer Research

Aug 06, 2021: Medivir: First-in-class histone deacetylase inhibitor gel shows promise for the treatment of patients with basal cell carcinoma

Jul 29, 2021: Shuttle Pharma awarded a new patent for selective inhibitors for cancer treatment

Jul 13, 2021: Tenaya Therapeutics unveils preclinical research supporting product candidate for rare and prevalent heart disease indications at ESC Heart Failure 2021

May 20, 2021: Positive results from investigator-initiated phase II clinical study of remetinostat in patients with squamous cell carcinoma published

Dec 07, 2020: Jubilant Therapeutics announces efficacy and biomarker data at 62nd ASH Annual Meeting for its Novel Dual LSD1-HDAC6 Inhibitor for the Treatment of Hematological Cancers

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Products under Development by Stage of Development, 2022

Number of Products under Development by Therapy Areas, 2022

Number of Products under Development by Indications, 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Companies, 2022 (Contd..1)

Products under Development by Companies, 2022

Number of Products under Investigation by Universities/Institutes, 2022

Products under Investigation by Universities/Institutes, 2022

Number of Products by Stage and Mechanism of Actions, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Pipeline by Annji Pharmaceutical Co Ltd, 2022

Pipeline by ATP Biopharm, 2022

Pipeline by Augustine Therapeutics, 2022

Pipeline by Avstera Therapeutics Inc, 2022

Pipeline by Beijing Konruns Pharmaceutical Co Ltd, 2022

Pipeline by Bristol-Myers Squibb Co, 2022

Pipeline by Chong Kun Dang Pharmaceutical Corporation, 2022

Pipeline by Convalife, 2022

Pipeline by CStone Pharmaceuticals Co Ltd, 2022

Pipeline by Curis Inc, 2022

Pipeline by Eikonizo Therapeutics Inc, 2022

Pipeline by Guangdong Zhongsheng Pharmaceutical Co Ltd, 2022

Pipeline by Hillstream BioPharma Inc, 2022

Pipeline by Jubilant Therapeutics Inc, 2022

Pipeline by Kancera AB, 2022

Pipeline by Karus Therapeutics Ltd, 2022

Pipeline by KYAN Therapeutics Inc, 2022

Pipeline by Medivir AB, 2022

Pipeline by Merck & Co Inc, 2022

Pipeline by Mycovia Pharmaceuticals Inc, 2022

Pipeline by OnKure Inc, 2022

Pipeline by Oryzon Genomics SA, 2022

Pipeline by Quimatryx SL, 2022

Pipeline by Shuttle Pharmaceuticals Inc, 2022

Pipeline by SK Biopharmaceuticals Co Ltd, 2022

Pipeline by Starwise Therapeutics LLC, 2022

Pipeline by Suzhou GenHouse Pharmaceutical Co Ltd, 2022

Pipeline by Tenaya Therapeutics Inc, 2022

Dormant Products, 2022

Figures

List of Figures

Number of Products under Development by Stage of Development, 2022

Number of Products under Development by Therapy Areas, 2022

Number of Products under Development by Top 10 Indications, 2022

Number of Products by Stage and Mechanism of Actions, 2022

Number of Products by Routes of Administration, 2022

Number of Products by Stage and Routes of Administration, 2022

Number of Products by Molecule Types, 2022

Number of Products by Stage and Molecule Types, 2022

Frequently asked questions

Histone Deacetylase 6 (Protein Phosphatase 1 Regulatory Subunit 90 or HDAC6 or EC 3.5.1.98) Drugs in Development by Therapy Areas and Indications, Stages, MoA, RoA, Molecule Type and Key Players, 2022 Update standard reports
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