Hypertrophic Cardiomyopathy Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

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Hypertrophic Cardiomyopathy (HCM) is a disease in which the heart muscle (myocardium) becomes abnormally thick (hypertrophied). The thickened heart muscles make it harder for the heart to pump blood. Symptoms include chest pain, especially during exercise, the sensation of rapid, fluttering, or pounding heartbeats, and heart murmur. HCM usually is inherited. Treatment includes beta blockers, calcium channel blockers and blood thinners.

The HCM pipeline drugs market research report provides comprehensive information on the therapeutics under development for Hypertrophic Cardiomyopathy, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history, and the latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for HCM and features dormant and discontinued projects.

HCM Pipeline Drugs Market Segmentation by Targets

Some of the targets of the HCM pipeline drugs market are Myosin, Myosin Binding Protein C Cardiac Type, cGMP Inhibited 3′,5′ Cyclic Phosphodiesterase A, G Protein Coupled Receptor Kinase 5, Myocyte Specific Enhancer Factor 2, Neprilysin, Short Transient Receptor Potential Channel 6, and Type 1 Angiotensin II Receptor.

HCM Pipeline Drugs Market Analysis, by Targets

HCM Pipeline Drugs Market Analysis, by Targets

For more HCM pipeline drugs market target insights, download a free report sample

HCM Pipeline Drugs Market Segmentation by Mechanism of Actions

Some of the mechanisms of action of the HCM pipeline drugs market are Myosin Inhibitor, Myosin Binding Protein C Cardiac Type Activator, cGMP Inhibited 3′,5′ Cyclic Phosphodiesterase A Inhibitor, G Protein Coupled Receptor Kinase 5 Inhibitor, Myocyte Specific Enhancer Factor 2 Inhibitor, Neprilysin Inhibitor, Short Transient Receptor Potential Channel 6 Blocker, and Type 1 Angiotensin II Receptor Antagonist.

HCM Pipeline Drugs Market Analysis, by Mechanism of Actions

HCM Pipeline Drugs Market Analysis, by Mechanism of Actions

For more mechanism of action insights into the HCM pipeline drugs market, download a free report sample

HCM Pipeline Drugs Market Segmentation by Routes of Administration

The key routes of administration in the HCM pipeline drugs market are oral and intravenous.

HCM Pipeline Drugs Market Analysis, by Routes of Administration

HCM Pipeline Drugs Market Analysis, by Routes of Administration

For more routes of administration insights into the HCM pipeline drugs market, download a free report sample

HCM Pipeline Drugs Market Segmentation by Molecule Types

The molecule types in the HCM pipeline drugs market are Small Molecule, Gene Therapy, Antisense Oligonucleotide, Recombinant Peptide.

HCM Pipeline Drugs Market Analysis, by Molecule Types

HCM Pipeline Drugs Market Analysis, by Molecule Types

For more molecule type insights into the HCM pipeline drugs market, download a free report sample

Competitive Landscape

Some of the key companies in the HCM pipeline drugs market are Bristol-Myers Squibb Co, DiNAQOR AG, Cytokinetics Inc, Cardior Pharmaceuticals GmbH, Algomedix Inc, BioMarin Pharmaceutical Inc, C&C BioPharma LLC, Celltrion Inc, Edgewise Therapeutics Inc, and Genome Biologics UG.

HCM Pipeline Drugs Market Analysis, by Companies

HCM Pipeline Drugs Market Analysis, by Companies

To know more about the HCM pipeline drugs market companies, download a free report sample

HCM Pipeline Drugs Market Report Overview

Key Targets Myosin, Myosin Binding Protein C Cardiac Type, cGMP Inhibited 3′,5′ Cyclic Phosphodiesterase A, G Protein Coupled Receptor Kinase 5, Myocyte Specific Enhancer Factor 2, Neprilysin, Short Transient Receptor Potential Channel 6, and Type 1 Angiotensin II Receptor
Key Mechanism of Actions Myosin Inhibitor, Myosin Binding Protein C Cardiac Type Activator, cGMP Inhibited 3′,5′ Cyclic Phosphodiesterase A Inhibitor, G Protein Coupled Receptor Kinase 5 Inhibitor, Myocyte Specific Enhancer Factor 2 Inhibitor, Neprilysin Inhibitor, Short Transient Receptor Potential Channel 6 Blocker, and Type 1 Angiotensin II Receptor Antagonist
Key Routes of Administration Oral and Intravenous
Key Molecule Types Small Molecule, Gene Therapy, Antisense Oligonucleotide, Recombinant Peptide
Key Companies Bristol-Myers Squibb Co, DiNAQOR AG, Cytokinetics Inc, Cardior Pharmaceuticals GmbH, Algomedix Inc, BioMarin Pharmaceutical Inc, C&C BioPharma LLC, Celltrion Inc, Edgewise Therapeutics Inc, and Genome Biologics UG

Scope

This report provides:

  • A snapshot of the global therapeutic landscape of Hypertrophic Cardiomyopathy.
  • Reviews of pipeline therapeutics for HCM by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • Pipeline products based on several stages of development ranging from pre-registration to discovery and undisclosed stages.
  • Descriptive drug profiles for the pipeline products which comprise product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • Reviews of key companies involved in HCM therapeutics and enlists all their major and minor projects.
  • Evaluation of HCM therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA), and molecule type.
  • All the dormant and discontinued pipeline projects.
  • Reviews of the latest news related to pipeline therapeutics for Hypertrophic Cardiomyopathy.

Reasons to Buy

  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with the potentially strong product portfolio and create effective counterstrategies to gain a competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Hypertrophic Cardiomyopathy.
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and their most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding HCM pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from the pipeline.

Algomedix Inc
BioMarin Pharmaceutical Inc
Bristol-Myers Squibb Co
C&C BioPharma LLC
Cardior Pharmaceuticals GmbH
Celltrion Inc
Cytokinetics Inc
DiNAQOR AG
Edgewise Therapeutics Inc
Genome Biologics UG
Haya Therapeutics SA
Igia Pharmaceuticals Inc
Imbria Pharmaceuticals Inc
Invivosciences Inc
Jaan Biotherapeutics LLC
Lead Discovery Center GmbH
LEXEO Therapeutics LLC
Novartis AG
Saliogen Therapeutics Inc
Tenaya Therapeutics Inc
Toa Eiyo Ltd

Table of Contents

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Hypertrophic Cardiomyopathy – Overview

Hypertrophic Cardiomyopathy – Therapeutics Development

Pipeline Overview

Pipeline by Companies

Pipeline by Universities/Institutes

Products under Development by Companies

Products under Development by Universities/Institutes

Hypertrophic Cardiomyopathy – Therapeutics Assessment

Assessment by Target

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Hypertrophic Cardiomyopathy – Companies Involved in Therapeutics Development

Algomedix Inc

BioMarin Pharmaceutical Inc

Bristol-Myers Squibb Co

C&C BioPharma LLC

Cardior Pharmaceuticals GmbH

Celltrion Inc

Cytokinetics Inc

DiNAQOR AG

Edgewise Therapeutics Inc

Genome Biologics UG

Haya Therapeutics SA

Igia Pharmaceuticals Inc

Imbria Pharmaceuticals Inc

Invivosciences Inc

Jaan Biotherapeutics LLC

Lead Discovery Center GmbH

LEXEO Therapeutics LLC

Novartis AG

Saliogen Therapeutics Inc

Tenaya Therapeutics Inc

Toa Eiyo Ltd

Hypertrophic Cardiomyopathy – Drug Profiles

(sacubitril + valsartan) – Drug Profile

Product Description

Mechanism Of Action

History of Events

8-MI – Drug Profile

Product Description

Mechanism Of Action

aficamten – Drug Profile

Product Description

Mechanism Of Action

History of Events

CDR-348T – Drug Profile

Product Description

Mechanism Of Action

CDR-641L – Drug Profile

Product Description

Mechanism Of Action

CK-271 – Drug Profile

Product Description

Mechanism Of Action

History of Events

CTG-20 – Drug Profile

Product Description

Mechanism Of Action

History of Events

dasatinib – Drug Profile

Product Description

Mechanism Of Action

History of Events

DINA-001 – Drug Profile

Product Description

Mechanism Of Action

History of Events

DINA-008 – Drug Profile

Product Description

Mechanism Of Action

DINA-009 – Drug Profile

Product Description

Mechanism Of Action

DINA-010 – Drug Profile

Product Description

Mechanism Of Action

DINA-011 – Drug Profile

Product Description

Mechanism Of Action

Drugs to Inhibit PDE3A1 for Hypertrophic Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

EDG-002 – Drug Profile

Product Description

Mechanism Of Action

GEN-387 – Drug Profile

Product Description

Mechanism Of Action

Gene therapy for Hypertrophic Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

GRK5 – Drug Profile

Product Description

Mechanism Of Action

HTX-001 – Drug Profile

Product Description

Mechanism Of Action

Hypertrophy Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

JN-210 – Drug Profile

Product Description

Mechanism Of Action

LX-2022 – Drug Profile

Product Description

Mechanism Of Action

History of Events

mavacamten – Drug Profile

Product Description

Mechanism Of Action

History of Events

MYK-224 – Drug Profile

Product Description

Mechanism Of Action

History of Events

MYK-581 – Drug Profile

Product Description

Mechanism Of Action

History of Events

ninerafaxstat – Drug Profile

Product Description

Mechanism Of Action

History of Events

Recombinant Peptides to Agonize MFN2 for Charcot Marie Tooth Disease Type IIA and Hypertrophic Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

Small Molecule for Cardiac Hypertrophy – Drug Profile

Product Description

Mechanism Of Action

Small Molecules for Hypertrophic Cardiomyopathy – Drug Profile

Product Description

Mechanism Of Action

History of Events

TN-201 – Drug Profile

Product Description

Mechanism Of Action

History of Events

TRPC6 ANTAGONIST – Drug Profile

Product Description

Mechanism Of Action

History of Events

TY-0305 – Drug Profile

Product Description

Mechanism Of Action

Hypertrophic Cardiomyopathy – Dormant Projects

Hypertrophic Cardiomyopathy – Product Development Milestones

Featured News & Press Releases

Aug 10, 2022: LianBio completes enrollment in pivotal phase 3 EXPLORER-CN trial of mavacamten in Chinese obstructive hypertrophic cardiomyopathy patients

Jun 13, 2022: Cytokinetics announces additional data from REDWOOD-HCM presented at the American Society of Echocardiography 33rd Annual Scientific Sessions

Jun 13, 2022: Cytokinetics announces additional results from REDWOOD-HCM to be presented at the American Society of Echocardiography 33rd Annual Scientific Sessions

May 23, 2022: Cytokinetics announces data from REDWOOD-HCM OLE presented as late breaking Science Presentations at the European Society of Cardiology Heart Failure 2022 Congress

May 09, 2022: LianBio Completes phase 1 pharmacokinetic study of mavacamten in Healthy Chinese Volunteers

Apr 29, 2022: BMS receives US FDA approval for Camzyos to treat cardiomyopathy

Apr 04, 2022: BMS’ mavacamten boosts cardiovascular outcomes in obstructive HCM study

Apr 02, 2022: Mavacamten demonstrated significant reduction in need for septal reduction therapy in symptomatic obstructive HCM patients in phase 3 VALOR trial

Apr 02, 2022: Cytokinetics announces results from cohort 3 of Redwood-HCM presented at American College of Cardiology 71st Annual Scientific Session

Mar 24, 2022: Cytokinetics announces presentations on aficamten at the American College of Cardiology 71st Annual Scientific Session & Expo

Mar 21, 2022: Bristol Myers Squibb to demonstrate the strength of its growing cardiovascular portfolio at the American College of Cardiology’s 71st annual scientific session

Mar 02, 2022: Cytokinetics announces Cohort 4 of REDWOOD-HCM is open to enrollment

Feb 23, 2022: Cytokinetics announces start of SEQUOIA-HCM, a phase 3 clinical trial of aficamten in patients with symptomatic obstructive hypertrophic cardiomyopathy

Feb 16, 2022: Jixing announces receipt of breakthrough therapy designation for AFICAMTEN in CHINA

Feb 16, 2022: Bristol Myers Squibb announces positive topline results from phase 3 VALOR-HCM trial, evaluating mavacamten in patients with obstructive hypertrophic cardiomyopathy who are eligible for septal reduction therapy

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

Table

List of Tables

Number of Products under Development for Hypertrophic Cardiomyopathy, 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Universities/Institutes, 2022

Products under Development by Companies, 2022

Products under Development by Companies, 2022 (Contd..1)

Products under Development by Universities/Institutes, 2022

Number of Products by Stage and Target, 2022

Number of Products by Stage and Mechanism of Action, 2022

Number of Products by Stage and Route of Administration, 2022

Number of Products by Stage and Molecule Type, 2022

Hypertrophic Cardiomyopathy – Pipeline by Algomedix Inc, 2022

Hypertrophic Cardiomyopathy – Pipeline by BioMarin Pharmaceutical Inc, 2022

Hypertrophic Cardiomyopathy – Pipeline by Bristol-Myers Squibb Co, 2022

Hypertrophic Cardiomyopathy – Pipeline by C&C BioPharma LLC, 2022

Hypertrophic Cardiomyopathy – Pipeline by Cardior Pharmaceuticals GmbH, 2022

Hypertrophic Cardiomyopathy – Pipeline by Celltrion Inc, 2022

Hypertrophic Cardiomyopathy – Pipeline by Cytokinetics Inc, 2022

Hypertrophic Cardiomyopathy – Pipeline by DiNAQOR AG, 2022

Hypertrophic Cardiomyopathy – Pipeline by Edgewise Therapeutics Inc, 2022

Hypertrophic Cardiomyopathy – Pipeline by Genome Biologics UG, 2022

Hypertrophic Cardiomyopathy – Pipeline by Haya Therapeutics SA, 2022

Hypertrophic Cardiomyopathy – Pipeline by Igia Pharmaceuticals Inc, 2022

Hypertrophic Cardiomyopathy – Pipeline by Imbria Pharmaceuticals Inc, 2022

Hypertrophic Cardiomyopathy – Pipeline by Invivosciences Inc, 2022

Hypertrophic Cardiomyopathy – Pipeline by Jaan Biotherapeutics LLC, 2022

Hypertrophic Cardiomyopathy – Pipeline by Lead Discovery Center GmbH, 2022

Hypertrophic Cardiomyopathy – Pipeline by LEXEO Therapeutics LLC, 2022

Hypertrophic Cardiomyopathy – Pipeline by Novartis AG, 2022

Hypertrophic Cardiomyopathy – Pipeline by Saliogen Therapeutics Inc, 2022

Hypertrophic Cardiomyopathy – Pipeline by Tenaya Therapeutics Inc, 2022

Hypertrophic Cardiomyopathy – Pipeline by Toa Eiyo Ltd, 2022

Hypertrophic Cardiomyopathy – Dormant Projects, 2022

Figures

List of Figures

Number of Products under Development for Hypertrophic Cardiomyopathy, 2022

Number of Products under Development by Companies, 2022

Number of Products under Development by Universities/Institutes, 2022

Number of Products by Targets, 2022

Number of Products by Stage and Targets, 2022

Number of Products by Mechanism of Actions, 2022

Number of Products by Stage and Mechanism of Actions, 2022

Number of Products by Routes of Administration, 2022

Number of Products by Stage and Routes of Administration, 2022

Number of Products by Molecule Types, 2022

Number of Products by Stage and Molecule Types, 2022

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